Orexin-A increases cell surface expression of AMPA receptors in the striatum
Keywords: اعتیاد به مواد مخدر; Orexin-A; AMPA receptor; Synaptic plasticity; Drug addiction
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Lower glutamate levels in rostral anterior cingulate of chronic cocaine users — A 1H-MRS study using TE-averaged PRESS at 3 T with an optimized quantification strategy
Keywords: اعتیاد به مواد مخدر; Drug addiction; Neurotransmitter; Relaxation; J-coupling
Normal and pathological personality characteristics in subtypes of drug addicts undergoing treatment
Keywords: اعتیاد به مواد مخدر; Drug addiction; Drug addict typologies; Psychopathological dimensions; Normal personality traits; Personality disorder traits
Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: Specific deficits in ‘waiting’ versus ‘stopping’
Keywords: اعتیاد به مواد مخدر; Impulsivity; Delay-discounting; Stop-signal reaction time; Autoshaping; Drug addiction; Attention-deficit hyperactivity disorder
Dopamine receptors in the learning, memory and drug reward circuitry
Keywords: اعتیاد به مواد مخدر; Drug addiction; Cocaine; Striatum; Conditioning; Nucleus accumbens
Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in μ, δ and κ opioid receptors
Keywords: اعتیاد به مواد مخدر; drug addiction; autoradiography; alternative splicing; ENUENU, N-ethyl-N-nitrosourea; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; N/OFQ, nociceptin/orphanin FQ; NOPr, nociceptin/orphanin FQ opioid peptide receptor; N.S, non-significant; oprl1, opioid
(1R, 3S)-(−)-Trans-PAT: A novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity
Keywords: اعتیاد به مواد مخدر; Drug addiction; Drug discovery; Obesity; Psychiatric disorder; Serotonin 5-HT2 receptor
Modelling human drug abuse and addiction with dedicated small animal positron emission tomography
Keywords: اعتیاد به مواد مخدر; Positron emission tomography; Drug addiction; Dopamine; Dopamine receptors; Noradrenaline; DAT; Impulsivity; Nucleus accumbens; Striatum; Cocaine
Different affective response to opioid withdrawal in adolescent and adult mice
Keywords: اعتیاد به مواد مخدر; Morphine; Dependence; Age-related differences; Forced swim test (FST); Locomotion; Drug addiction
Patients usagers d'opiacés : accueil et prise en charge au sein des services d'urgence. Audit en Gironde au sein des principaux services d'urgence et auprès des entités spécialisées en addictologie
Keywords: اعتیاد به مواد مخدر; Addictologie; Audit de pratique; Buprénorphine; Dépendance aux opiacés; Méthadone; Prise en charge; Toxicomanies; Traitement de substitution; Urgences; Drug addiction; Audit; Buprenorphine; Opiate addiction; Methadone; Management; Drug abuse; Treatmen
Orexin-A acts on the paraventricular nucleus of the midline thalamus to inhibit locomotor activity in rats
Keywords: اعتیاد به مواد مخدر; Orexin; Hypocretin; Midline thalamic nuclei; Paraventricular nucleus of thalamus; Locomotion; Morphine; Arousal; Drug addiction; Sensitization
Conditioned cues and the expression of stimulant sensitization in animals and humans
Keywords: اعتیاد به مواد مخدر; Conditioned inhibition; Conditioning; Dopamine; Drug addiction; Drug self-administration; Excitatory Pavlovian conditioning; Facilitation; Occasion setters; Sensitization
Sex differences in the self-administration of cannabinoids and other drugs of abuse
Keywords: اعتیاد به مواد مخدر; Sex; Gender differences; Gonadal hormones; Self-administration; Drug addiction; Relapse
Neurotrophic factors and structural plasticity in addiction
Keywords: اعتیاد به مواد مخدر; Growth factors; Drug addiction; Dendritic spines; Brain derived neurotrophic factor; Nerve growth factor; Intracellular signaling; Neurotrophic factors; Morphine; Cocaine; Reward; Relapse; Actin polymerization; Neuron Morphology; ERK; Akt; PI3 kinase; NF
Nicotinic receptor ligands reduce ethanol intake by high alcohol–drinking HAD-2 rats
Keywords: اعتیاد به مواد مخدر; Drug addiction; Nicotinic receptor; Alcohol consumption; Selectively bred rats; Cytisine; Lobeline
Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodents
Keywords: اعتیاد به مواد مخدر; GABA-B receptor; Nicotine self-administration; Place conditioning; Reinstatement; Relapse; Drug addiction
Fentanyl, but not haloperidol, entrains persisting circadian activity episodes when administered at 24- and 31-h intervals
Keywords: اعتیاد به مواد مخدر; Fentanyl; Haloperidol; Drug addiction; Drug abuse; Circadian rhythms; Locomotor entrainment; Drug anticipation; Ensuing activity; Wheel running
Viral vector approaches to modify gene expression in the brain
Keywords: اعتیاد به مواد مخدر; Viral vectors; Synaptic plasticity; Learning and memory; Drug addiction; AMPAR; CREB
kappa-Opioid receptor signaling and brain reward function
Keywords: اعتیاد به مواد مخدر; Dynorphins; Neuropeptides; Brain reward function; Negative mood state; Drug addiction
Neurobiological mechanisms of the reinstatement of drug-conditioned place preference
Keywords: اعتیاد به مواد مخدر; Conditioned place preference; Reinstatement; Drug priming; Stress; Drug addiction
Tat-3L4F does not significantly affect spatial learning and memory
Keywords: اعتیاد به مواد مخدر; Tat-3L4F; Learning and memory; Morris water maze; Drug addiction; 5-HT2C receptor; Cannabinoid; PTEN
A Single Dose of Nicotine Enhances Reward Responsiveness in Nonsmokers: Implications for Development of Dependence
Keywords: اعتیاد به مواد مخدر; Anhedonia; drug addiction; nicotine; nonsmokers; reward; reward responsiveness;
Toxicomanie chez la femme enceinte. Prise en charge spécialisée à Port-Royal entre 1998 et 2007
Keywords: اعتیاد به مواد مخدر; Sage-femme; Maternité; Substances psychoactives et grossesse; Toxicomanie; Ãquipe d'addictologie; Midwife; Maternity; Psychoactive substances and pregnancy; Drug addiction; Drug addiction team;
Increased Expression of 5-HT6 Receptors in the Nucleus Accumbens Blocks the Rewarding But Not Psychomotor Activating Properties of Cocaine
Keywords: اعتیاد به مواد مخدر; Conditioned place preference; drug addiction; psychomotor stimulant; rat; serotonin; viral-mediated gene transfer
Opposing roles for the nucleus accumbens core and shell in cue-induced reinstatement of food-seeking behavior
Keywords: اعتیاد به مواد مخدر; pavlovian conditioning; instrumental learning; drug addiction; relapse; ratAP, anteroposterior; BLA, basolateral amygdale; CS, conditioned stimulus; DV, dorsoventral; ML, mediolateral; NAc, nucleus accumbens; PFC, prefrontal cortex; PIT, pavlovian-to-inst
The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization
Keywords: اعتیاد به مواد مخدر; Basal ganglia; Hippocampus; Anandamide; 2-Arachidonoylglycerol; Psychostimulant; Rimonabant; Drug addiction; Mouse
The CB1 cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus
Keywords: اعتیاد به مواد مخدر; Basal ganglia; Drug addiction; Craving; CB1 receptor; Mouse
Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: Role of μ-opioid receptors
Keywords: اعتیاد به مواد مخدر; mesolimbic system; drug addiction; postsynaptic currents; APV; dl-2-amino-5-phosphono-valeric acid; BIC; bicuculline; CGP 52432; 3-[[(3,4-dichlorophenol) methyl] amino] propyl] diethoxymethyl) phosphinic acid; DA; dopaminergic; DAMGO; Tyr-d-Ala-Gly-N-Me-P
SPECT neuroimaging in translational research of CNS disorders
Keywords: اعتیاد به مواد مخدر; SPECT/CT imaging; MicroPET imaging; CNS disorders; Gene-manipulated mice; Spatial resolution; Dopamine; Serotonin; Cerebral blood flow; Drug addiction; Parkinson's disease
Differential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: Implications for understanding the “switch” to opiate addiction
Keywords: اعتیاد به مواد مخدر; post-translational processing; opiates; endorphin; TRH; hypothalamus; drug addiction; AHiAL; anterolateral nucleus of the amygdala; ATF-1; activation transcription factor-1; CRE; cyclic AMP-response element; CREM; cAMP response element modulator; CRH; cor
School-based prevention for illicit drugs use: A systematic review
Keywords: اعتیاد به مواد مخدر; Drug addiction; Prevention; School-based programs; Systematic review; Effectiveness; RCT; Cochrane collaboration
Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology
Keywords: اعتیاد به مواد مخدر; Heteromerization; Striatum; Dopamine receptor; CB1 receptor; Adenosine receptor; mGluR5; 5-HT1A receptor; Galanin receptor; Parkinson's disease; Schizophrenia; Drug addiction; Depression; Treatment strategy;
Drug fluency: A potential marker for cocaine use disorders
Keywords: اعتیاد به مواد مخدر; Semantic memory; Cocaine; Drug addiction; Salience; Cue-reactivity; Craving; Prefrontal cortex
Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells
Keywords: اعتیاد به مواد مخدر; Drug Addiction; Oxidative stress; Protein oxidation; Inflammatory; Drug abuse
Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABAB receptors
Keywords: اعتیاد به مواد مخدر; GABAB positive allosteric modulators; GS39783; Drug addiction
Are all drug addicts impulsive? Effects of antisociality and extent of multidrug use on cognitive and motor impulsivity
Keywords: اعتیاد به مواد مخدر; Drug addiction; Impulsivity; Antisocial; Polysubstance use; Multidrug use; Decision-making
Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction
Keywords: اعتیاد به مواد مخدر; emotional Stroop interference; inhibitory control; cognitive conflict; attention bias; drug addiction; fMRI BOLDACC, anterior cingulate cortex; BOLD, blood-oxygenation level dependent; cdACC, caudal–dorsal anterior cingulate cortex; DSM-IV, Diagnostic and
Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function
Keywords: اعتیاد به مواد مخدر; Dopamine D1 receptor; Dopamine D2 receptor; Adenosine A1 receptor; Adenosine A2A receptor; Heteromeric receptor complexes; Parkinson's disease; Schizophrenia; Drug addiction
Rostral-caudal differences in the effects of intra-VTA muscimol on cocaine self-administration
Keywords: اعتیاد به مواد مخدر; Operant responding; Reinforcement; Drug abuse; Drug addiction; Motivation; Cocaine; Self-administration; Progressive ratio; Fixed ratio;
The role of different subregions of the basolateral amygdala in cue-induced reinstatement and extinction of food-seeking behavior
Keywords: اعتیاد به مواد مخدر; pavlovian conditioning; instrumental learning; drug addiction; relapse; rat; BLA; basolateral amygdala; CS; conditioned stimulus; FR; fixed ratio; VR; variable ratio;
Neonatal immune system activation with lipopolysaccharide enhances behavioural sensitization to the dopamine agonist, quinpirole, in adult female but not male rats
Keywords: اعتیاد به مواد مخدر; Immune activation; Endotoxin; Lipopolysaccharide; Neonatal; Sex differences; Sensitization; Dopamine agonist; Quinpirole; Drug addiction; Locomotor activity
Regulation of fosB and ΔfosB mRNA expression: In vivo and in vitro studies
Keywords: اعتیاد به مواد مخدر; PTB, polypyrimidine tract binding protein; AP-1, activator protein-1; PMA, phorbol 12-myristate 13-acetate; PC12 cells, rat adrenal pheochromocytoma cellsΔFosB; PTB; Splicing; Drug addiction; Stress; mRNA
The effect of practice on a sustained attention task in cocaine abusers
Keywords: اعتیاد به مواد مخدر; fMRI BOLD; Adaptation; Practice effects; Prefrontal cortex; Alertness; Drug abuse; Drug addiction; Salience; Reward;
Rationality and drug use: An experimental approach
Keywords: اعتیاد به مواد مخدر; C91; D81; D91; I12; Drug addiction; Experiments; Time; Risk;
Drug addiction: Pathways to the disease and pathophysiological perspectives
Keywords: اعتیاد به مواد مخدر; Drug addiction; Definition physiopathology
The attribution of incentive salience to a stimulus that signals an intravenous injection of cocaine
Keywords: اعتیاد به مواد مخدر; Pavlovian conditioning; Drug addiction; Conditioned stimuli; Autoshaping; Sign-tracking; Motivation
Odor perception in patients with mood disorders
Keywords: اعتیاد به مواد مخدر; Odor; Depression; Anorexia; Alcoholism; Drug addiction
Particularités des infections ostéoarticulaires chez les patients VIH positifs et les toxicomanes
Keywords: اعتیاد به مواد مخدر; VIH; Toxicomanie; Arthrite; Spondylodiscite; Ostéite; VIH infection; Drug addiction; Arthritis; Spondylodiscitis; Osteitis;
18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats
Keywords: اعتیاد به مواد مخدر; 18-Methoxycoronaridine; α-Conotoxin AuIB; Mecamylamine; Morphine; Medial habenula; Interpeduncular nucleus; Nicotine receptors; Drug addiction
Post-training amphetamine administration enhances memory consolidation in appetitive Pavlovian conditioning: Implications for drug addiction
Keywords: اعتیاد به مواد مخدر; Pavlovian conditioning; Amphetamine; Drug addiction; Memory consolidation; Learning; Post-training; Classical conditioning