دانلود مقالات ISI درباره DSB، شکست دو رشته DNA + ترجمه فارسی

RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects

Keywords: DSB، شکست دو رشته DNA; HR, homologous recombination; HDR, homology-directed (DNA) repair; DSB, DNA double-strand break; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; SSB, ssDNA binding protein; WT, wild-typeRAD51; Recombination; Homology-directed repair; Cancer; Varia

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Induction of DNA–protein cross-links by ionizing radiation and their elimination from the genome

Keywords: DSB، شکست دو رشته DNA; DPC, DNA–protein cross-link; rDPC, rapidly removed DPC; sDPC, slowly removed DPC; DSB, DNA double-strand break; rDSB, rapidly removed DSB; sDSB, slowly removed DSB; LET, linear energy transfer; ANCOVA, analysis of covariance; FITC, fluorescein isothiocyan

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The C-terminal region of Rad52 is essential for Rad52 nuclear and nucleolar localization, and accumulation at DNA damage sites immediately after irradiation

Keywords: DSB، شکست دو رشته DNA; CTR, C-terminal region; DIC, differential interference contrast; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; DSB, DNA double-strand break; HR, homologous recombination; NLS, nuclear localization signal; NHEJ, nonhomologous DNA-end-joining; S

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Structure and function of the DNA ligases encoded by the mammalian LIG3 gene

Keywords: DSB، شکست دو رشته DNA; BRCT, breast cancer susceptibility protein 1-related C-terminal; DBD, DNA binding domain; DNA PK, DNA-dependent protein kinase; DSB, DNA double-strand break; LIG, DNA ligase encoding gene; MLS, mitochondrial leader sequence; NEIL, Nei endonoclease VIII-li

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Cis-9,trans-11-conjugated linoleic acid affects lipid raft composition and sensitizes human colorectal adenocarcinoma HT-29 cells to X-radiation

Keywords: DSB، شکست دو رشته DNA; CLA, conjugated linoleic acid(s); DNA-PK, DNA-dependent protein kinase; DSB, DNA double-strand break; EGFR, epidermal growth factor receptor; FAME, fatty acid methyl ester(s); GC, gas chromatography; LA, linoleic acid; mFISH, multicolour fluorescence in s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

A new mechanism to ensure integration during LINE retrotransposition: A suggestion from analyses of the 5′ extra nucleotides

Keywords: DSB، شکست دو رشته DNA; ATM, ataxia-telangiectasia mutated; bp, base pair; DSB, DNA double-strand break; kbp, kilo base pair; LINE, long interspersed element; mRNA, messenger RNA; NHEJ, non-homologous end joining; ORF, open reading frame; RT, reverse transcriptase; TPRT, target-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity

Keywords: DSB، شکست دو رشته DNA; C, ceramide; CTGF, connective tissue growth factor; Doxo, doxorubicin; DHC, dihydro-ceramide; DHSph, dihydro-sphingosine; DSB, DNA double-strand break; GPT, glutamate pyruvate transaminase (= ALT); GLDH, glutamate dehydrogenase; gpx1, glutathione peroxida

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Accumulation of p21 proteins at DNA damage sites independent of p53 and core NHEJ factors following irradiation

Keywords: DSB، شکست دو رشته DNA; CDK, cyclin-dependent kinase; DIC, differential interference contrast; DNA-PK, DNA-dependent protein kinase; DSB, DNA double-strand break; HPV, human papillomaviruses; HR, homologous recombination; MLE, murine lung epithelial cell line; NHEJ, nonhomologou

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

DNA-binding properties of Smc6, a core component of the Smc5–6 DNA repair complex

Keywords: DSB، شکست دو رشته DNA; CV, column volume; DSB, DNA double-strand break; EMSA, electrophoretic mobility shift assay; HST, 9xHIS-3xStreptagII tag; SMC, Structural maintenance of chromosomes; dsDNA, double-stranded DNA; ssDNA, single-stranded DNADNA repair; Genome integrity; Struc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Mode of ATM-dependent suppression of chromosome translocation

Keywords: DSB، شکست دو رشته DNA; ATM, ataxia telangiectasia mutated; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-dependent protein kinase catalytic subunit; DSB, DNA double-strand break; IR, ionizing radiation; NHEJ, non-homologous end-joining; MMEJ, microhomology-mediated end-jo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells

Keywords: DSB، شکست دو رشته DNA; ATM, ataxia telangiectasia mutated; DSB, DNA double-strand break; NHEJ, nonhomologous DNA-end-joining; DNA-PK, DNA-dependent protein kinase; PTMs, Posttranslational protein modifications; MLE, murine lung epithelial; TSA, Tricostatin A; HDAC, histone deac

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

KARP-1 works as a heterodimer with Ku70, but the function of KARP-1 cannot perfectly replace that of Ku80 in DSB repair

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; KARP-1, Ku86 autoantigen related protein-1; NHEJ, non-homologous end-joining; NLS, nuclear localization signalDNA repair; KARP-1; Ku70; Ku80; Nuclear localization signal; Radiation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Influence of homologous recombinational repair on cell survival and chromosomal aberration induction during the cell cycle in γ-irradiated CHO cells

Keywords: DSB، شکست دو رشته DNA; CA, chromosomal aberration; DSB, DNA double-strand break; HRR, homologous recombinational repair; IR, ionizing radiation; NHEJ, non-homologous end-joining; SSA, single-strand annealingRadiosensitivity; Cell cycle; Homologous recombinational repair; Non-ho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells

Keywords: DSB، شکست دو رشته DNA; ActD, Actinomycin D; AT, Ataxia Telangiectasia; DSB, DNA double-strand break; IR, ionizing radiation; LMB, leptomycin B; NBS, Nijmegen Breakage Syndrome; α-PFT, α pifithrin; μ-PFT, μ pifithrin; PI, propidium iodideAtaxia Telangiectasia; Nijmegen Breakage

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Pathways for Double-strand Break Repair in Genetically Unstable Z-DNA-forming Sequences

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; NHEJ, non-homologous end-joining; HR, homologous recombination; ssDNA, single-stranded DNA; WT, wild type; LMPCR, linker-mediated PCR; Mt, Mycobacterium tuberculosisZ-DNA; DNA double-strand break; genetic instability; non-hom

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

Keywords: DSB، شکست دو رشته DNA; 8-oxo-dG, 8-oxo-7,8-dihydro-2′-deoxyguanosine; 8-oxoG, 8-oxoguanine; BER, base excision repair; DDR, DNA damage response; dNTP, deoxyribonucleotide triphosphate; DSB, DNA double-strand break; ETC, electron transport chain; hTERT, human telomeric reverse t

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Higher-order chromatin structure in DSB induction, repair and misrepair

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; γH2AX, histone H2AX phosphorylated on serine 139; PFGE, pulse-field gel electrophoreses; PI, post-irradiation; IR, ionizing radiation; IRIF, ionizing radiation-induced foci; RIDGE, regions of increased gene expression; antiRI

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Enhanced radiation damage in irradiated and non-irradiated bystander regions by co-exposure to myosmine

Keywords: DSB، شکست دو رشته DNA; MN, micronucleus; DSB, DNA double-strand break; LET, linear energy transfer; HPB, 4-hydroxy-1-(3-pyridyl)-1-butanone; keto acid, 4-oxo-4-(3-pyridyl)butanoic acid; RIBE, radiation-induced bystander effects; γ-H2AX, phosphorylated form of H2AX protein; c-PT

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

Keywords: DSB، شکست دو رشته DNA; DDR, DNA damage response; DSB, DNA double-strand break; IRIF, irradiation-induced foci; γIR, γ-ray irradiationSirt1; Tip60; H2AX; IR-induced foci (IRIF)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Tissue-specific DNA-PK-dependent H2AX phosphorylation and γ-H2AX elimination after X-irradiation in vivo

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; ECL, enhanced chemiluminescence; γ-H2AX, phosphorylated H2AXATM; DNA-PKcs; Histone H2AX phosphorylation; Ionizing radiation; SCID

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Modulation of the DNA-damage response to HZE particles by shielding

Keywords: DSB، شکست دو رشته DNA; Z, atomic number; HZE, high atomic number and high energy; LET, linear energy transfer; GCRs, galactic cosmic rays; DSB, DNA double-strand break; DDR, DNA-damage response; HSF, human skin fibroblast; PE, polyethylene; NSRL, NASA Space Radiation Research L

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Dynamic change of histone H2AX phosphorylation independent of ATM and DNA-PK in mouse skin in situ

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; ECL, enhanced chemiluminescence; ORS, outer root sheath; γ-H2AX, phosphorylated H2AXATM; DNA-PKcs; Histone H2AX phosphorylation; Ionizing radiation; Skin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Chemotherapy-related secondary leukemias: A role for DNA repair by error-prone non-homologous end joining in topoisomerase II — Induced chromosomal rearrangements

Keywords: DSB، شکست دو رشته DNA; topoII, DNA topoisomerase II; DSB, DNA double-strand break; NHEJ, non-homologous end joining; bcr, breakpoint cluster region; MAR, matrix association region; ChIP, chromatin immunoprecipitation; VP16, etoposide.AML1/RUNX1 gene; Breakpoint cluster region;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Elevated sodium chloride concentrations enhance the bystander effects induced by low dose alpha-particle irradiation

Keywords: DSB، شکست دو رشته DNA; d-NMMA, NG-methyl-d-arginine; l-NMMA, NG-methyl-l-arginine; DSB, DNA double-strand break; NO, nitric oxide; γ-H2AX, phosphorylated form of H2AX protein; RIBE, radiation-induced bystander effects; ROS, reactive oxygen species; MN, MicronucleiElevated NaCl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Rad52 and Rad59 exhibit both overlapping and distinct functions

Keywords: DSB، شکست دو رشته DNA; YFP, yellow fluorescent protein; CFP, cyan fluorescent protein; DSB, DNA double-strand break; HR, homologous recombination; dHJ, double Holliday junction; Hs, Homo sapiens; Sc, Saccharomyces cerevisiae; NLS, nuclear localization signalRad52; Rad59; Recomb

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Homologous recombination is involved in repair of chromium-induced DNA damage in mammalian cells

Keywords: DSB، شکست دو رشته DNA; AP site, apurinic/apyrimidinic site; BER, base excision repair; CA, chromosomal aberrations; DSB, DNA double-strand break; HAsT, hypoxanthine-l-azaserine-thymidine; HBSS, Hank's balanced salt solution; hprt, hypoxanthine-guanine phosphoribosyltransferase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

CeBRC-2 Stimulates D-loop Formation by RAD-51 and Promotes DNA Single-strand Annealing

Keywords: DSB، شکست دو رشته DNA; DSB, DNA double-strand break; NHEJ, non-homologous end joining; SSA, single-strand annealing; HR, homologous recombination; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; OB, oligonucleotide/oligosaccharide-binding; WT, wild-typeBRCA2; RAD51; rep

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

Keywords: DSB، شکست دو رشته DNA; ATM, ataxia telangiectasia mutated kinase; CHO, Chinese hamster ovary; DAPI, 4,6-diamidino-2-phenylindole; DNA-PK, DNA-dependent protein kinase; DSB, DNA double-strand break; HSF, human skin fibroblast; IR, ionizing radiation; PCD, programmed cell death;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه