Keywords: Folate pathway; Trypanosomatids; Structure-based drug design; Selective inhibition; Enzyme inhibitor; Anti-parasitic drug; PTR1; Pteridine reductase 1; DHFR; Dihydrofolate reductase; dUMP; Deoxyuridine monophosphate; dTMP; Deoxythymidine monophosphate; hD
مقالات ISI (ترجمه نشده)
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Keywords: AMP; adenosine 5â²-monophosphate; ADP; adenosine 5â²-diphosphate; ATP; adenosine 5â²-triphosphate; CMP; cytidine 5â²-monophosphate; CDP; cytidine 5â²-diphosphate; CTP; cytidine 5â²-triphosphate; dCMP; 2â²-deoxycytidine 5â²-monophosphate; dCTP; 2â
Keywords: HIV; human immunodeficiency virus; LTBI; latent tuberculosis infection; MDR-TB; multidrug-drug resistant tuberculosis; Mtb; Mycobacterium tuberculosis; TMPK; thymidine monophosphate kinase; dTMP; thymidine 5â²-monophosphate; dTDP; thymidine 5â²-diphosph
Keywords: Diagenesis; Bacteria; Biopolymers; DOP; DTMP; Guanabara Bay;
Neoadjuvant systemic treatment for breast cancer in Italy: The Italian Society of Surgical Oncology (SICO) Breast Oncoteam survey
Keywords: Neoadjuvant; Breast cancer; Multidisciplinary; Breast surgery; Pathological complete response; NAT; NeoAdjuvant systemic Treatment; SICO; Italian Society of Surgical Oncology; DTMP; Diagnostic Therapeutic and Healthcare Management Protocol; QoL; Quality o
ZH-1 enhances the anticancer activity of gemcitabine via deoxyribonucleotide synthesis and apoptotic pathway against A549 cells
Keywords: Gemcitabine; ZH-1; Apoptosis; Deoxyribonucleotides; Intrinsic apoptotic pathway; ATCC; American Type Culture Collection; ATP; adenosine-triphosphate; ATP13C15N; trioctylamine, 1,1,2-trichlorotrifluoroethane, stable isotope labeled adenosine-13C1015N5-trip
Glutathione metabolism links FOXRED1 to NADH:ubiquinone oxidoreductase (complex I) deficiency: A hypothesis
Keywords: ABC; ATP-binding cassette; ADH3; alcohol dehydrogenase 3; ALDH; aldehyde dehydrogenase; CFTR; cystic fibrosis transmembrane conductance regulator; CPS1; carbamoyl phosphate synthase; DMGDH; dimethylglycine dehydrogenase; DHF; dihydrofolate; DMGO; dimethyl
Redesigning the leaving group in nucleic acid polymerization
Keywords: 3-phosphono-l-Ala; 3-phosphono-l-alanine; ALG; alternative leaving groups; ADP; adenosine diphosphate; AMP; adenosine monophosphate; ATP; adenosine triphosphate; CoASH; coenzyme A; dCMP; deoxycytidine monophosphate; dGMP; deoxyguanosine monophosphate; DNA
Redox status and heavy metal risk in intertidal sediments in NW Spain as inferred from the degrees of pyritization of iron and trace elements
Keywords: Diagenesis; Suboxic marine sediments; Pyrite; DTMP; Trace metals; Mariculture
Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target
Keywords: SHMT; serine hydroxymethyltransferase; PfSHMT; Plasmodium falciparum serine hydroxymethyltransferase; Pv; P. vivax; dTMP; deoxythymidine 5â²-monophosphate; H4folate; (6RS)-tetrahydrofolate; CH2-H4folate; 5,10-methylenetetrahydrofolate; CH3-H4folate; 5-me
Methylenetetrahydrofolate reductase (MTHFR) C677T and thymidylate synthase promoter (TSER) polymorphisms in Indonesian children with and without leukemia
Keywords: ALL; acute lymphoblastic leukemia; CH2-THF; 5,10-methylenetetrahydrofolate; DDH; double distilled water; DHF; dihydrofolate; DHFR; dihydrofolate reductase; dTMP; deoxythymidine monophosphate; dTTP; deoxythymidine triphosphate; dUMP; deoxyuridine monophosp
The degree of trace metal pyritization in subtidal sediments of a mariculture area: Application to the assessment of toxic risk
Keywords: Diagenesis; Anoxic marine sediments; Pyrite; DTMP; Trace element; Shallow coastal environment
The theoretical study of one-carbon unit transfer with H2O participation from imidazolidine to dUMP analogue
Keywords: Folate cofactor; One-carbon unit transfer; ONIOM; dUMP; dTMP
Metabolic regulation and chemotherapy
Keywords: GPRT; guanine phosphoribosyltransferase (EC 2.4.2.8); IMP DH; inosine 5'-monophosphate dehydrogenase (EC 1.1.1.205); IP3; inositol-1; 4; 5-trisphosphate; MTX; methotrexate; NCI; National Cancer Institute; R-5-P; ribose-5-phosphate; PI; 1-phosphatidylino
Inhibition of thymidine phosphorylase (PD-ECGF) from SD-lymphoma by phosphonomethoxyalkyl thymines
Keywords: (S)-HPMPC; 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-cytosine; (R)-PMPA; 9-(R)-[2-(phosphonomethoxy)propyl]adenine; PME; 9-[2-(phosphonomethoxy)ethyl]; PMEDAP; 9-[2-(phosphonomethoxy)ethyl]-2,6-diamino-purine; PMEG; 9-[2-(phosphonomethoxy)ethyl]guanine
Entamoeba histolytica: Observations on metabolism based on the genome sequence
Keywords: TCA; tricarboxylic acid; PFOR; pyruvate:ferredoxin oxidoreductase; ATP; adenosine triphosphate; NAD; nicotinamide adenine dinucleotide; BLAST; basic local alignment search tool; ACS; acetyl-coA synthase; dTMP; deoxythymidine monophosphate; dUMP; deoxyurid
Bis(pivaloyloxymethyl) thymidine 5â²-phosphate is a cell membrane-permeable precursor of thymidine 5â²-phosphate in thymidine kinase deficient CCRF CEM cells
Keywords: POM; pivaloyloxymethyl; POM2; bis(pivaloyloxymethyl); TdR; thymidine; ddT; dideoxythymidine; dTMP; thymidine 5â²-phosphate; ddTMP; dideoxythymidine 5â²-phosphate; dTTP; thymidine 5â²-triphosphate; NTP; nucleoside triphosphate; CCRF CEM; human acute leu
Subunit complementation of thymidylate synthase in Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase
Keywords: Pf; Plasmodium falciparum; Lc; Lactobacillus casei; DHFR; dihydrofolate reductase; TS; thymidylate synthase; DHFR-TS; dihydrofolate reductase-thymidylate synthase; dUMP; deoxyuridine 5â²-monophosphate; dTMP; deoxythymidine 5â²-monophosphate; CH2H4folate
Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-κB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on human hepatoma cell
Keywords: IdUrd; iododeoxyuridine; TS; thymidylate synthase; 5-FU; 5-fluorouracil; PDTC; pyrrolidinodithiocarbamte; PB; phenylbutyrate; PBS; phosphate buffered saline; DMEM; Dulbecco's modified Eagle's medium; dUMP; deoxyuridine monophosphate; dTMP; thymidine monop
Trace elements in biodeposits and sediments from mussel culture in the RÃa de Arousa (Galicia, NW Spain)
Keywords: Aquaculture; Mussel; Biodeposits; Sediments; Trace elements; Pyritization; RÃa; Galicia; AVS; Acid Volatile Sulfide; DOP; degree of pyritization of Fe; DTMP; degree of trace metal pyritization;
Monitoring fluoropyrimidine metabolism in solid tumors with in vivo 19F magnetic resonance spectroscopy
Keywords: ACC; advanced colorectal cancer; ADEPT; antibody-directed enzyme-prodrug therapy; BAU; 5-benzylacyclouridine; B0; static magnetic field; Beff; effective magnetic field; CNDP; 3-cyano-2,6-dihydroxypyridine; 5â²-DFCR; 5â²-deoxy-5-fluorocytidine; 5â²-DFUR
Folate and its preventive potential in colorectal carcinogenesis.
Keywords: Pte; pteroic acid; PteGlu; pteroylglutamic acid or folic acid; PteGlun; pteroylpolyglutamates or folates; H2PteGlun; 7,8-dihydrofolate; H4PteGlun; 5,6,7,8-tetrahydrofolates; 5-CH3-H4PteGlun; 5-methyl-tetrahydrofolate; 5-HCO-H4PteGlun; 5-formyl-tetrahydrof