Keywords: BA; bile acid; BEI; biliary excretion index; BSEP/Bsep; bile salt export pump; CsA; cyclosporine A; DILI; drug-induced liver injury; DMSO; dimethyl sulfoxide; E217βG; estradiol-17β-D-glucuronide; FBS; fetal bovine serum; GFP; green fluorescent protein;
مقالات ISI (ترجمه نشده)
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Structural patterns of the human ABCC4/MRP4 exporter in lipid bilayers rationalize clinically observed polymorphisms
Keywords: 6-MP; 6-mercaptopurine; ABC; ATP-binding cassette; ADV; adefovir; AZT; azidothymidine; BLOSUM; blocks substitution matrix; CFTR; cystic fibrosis transmembrane conductance regulator; Chol; cholesterol; cryo-EM; cryo-electronic microscopy; DMAV; dimethylars
Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport
Keywords: drug transport; drug interactions; organic anion-transporting polypeptide transporters; hepatocytes; hepatic transport; pharmacokinetics; physiologically based pharmacokinetic modeling; AUC; area under the plasma concentration-time curve; CsA; cyclosporin
Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban
Keywords: drug interactions; solute transporters; organic anion transporters (OAT); pharmacokinetics/pharmacodynamics; renal transport; BCRP; breast cancer resistance protein; CCK8; cholecystokinin-8; E217βG; estradiol 17β-D-glucuronide; E-sul; estrone 3-sulfate;
Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions
Keywords: AsIII; arsenite; AsV; arsenate; As2O3; arsenic trioxide; ABC; ATP-binding cassette; CFTR; cystic fibrosis transmembrane conductance regulator; DAPI; 4â²,6-diamidino-2-phenylindole; DMAV; dimethylarsinic acid; DMAIII; dimethylarsinous acid; E217βG; 17β-
Substrate translocation and stimulated ATP hydrolysis of human ABC transporter MRP3 show positive cooperativity and are half-coupled
Keywords: CDCF; 5(6)-carboxy-2â²,7â²-dichlorofluorescein; DDM; n-dodecyl β-d-maltoside; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; E217βG; β-estradiol 17-(β-d-glucuronide); LTC4; leukotriene C4; MRP; multidrug resistance-associated protein; MTX; methotrex
Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter
Keywords: MRP; multidrug resistance protein; ABC; ATP-binding cassette; MSD; membrane spanning domain; NBD; nucleotide binding domain; LTC4; leukotriene C4; E217βG; 17β-estradiol 17β-d-glucuronide; CL; cytoplasmic loop; MTX; methotrexate; HEK; human embryonic ki
Human renal organic anion transporters: Characteristics and contributions to drug and drug metabolite excretion
Keywords: Kidney; Organic anions; Transport; Human; Excretion; α-KG; α-ketoglutarate; aa; amino acid; ABCC; Family C of the ATP-binding cassette superfamily; AG; acetaminophen glucuronide; BBM; brush border membrane; BLM; basolateral membrane; DHEAS; dehydroepian
Directional trans-epithelial transport of organic anions in porcine LLC-PK1 cells that co-express human OATP1B1 (OATP-C) and MRP2
Keywords: BSA; bovine serum albumin; DHEAS; Dehydroepiandrosterone-sulfate; E217βG; 17β-estradiol-17β-glucuronide; E1S; estrone 3-sulfate; FBS; fetal bovine serum; HA; hemagglutinin; HBSS; Hanks balanced salt solution; MDCK; Mardin Darby canine kidney cells; M
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas
Keywords: ABC; ATP-binding cassette; MRP; multidrug resistance protein; BCRP; breast cancer resistance protein; LTC4; leukotriene C4; E217βG; 17β-estradiol-17-β-(d-glucuronide); NBD; nucleotide binding domain; MSD; membrane spanning domain; TM; transmembrane; CL
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites
Keywords: ABC; ATP-binding cassette; MRP; multidrug resistance protein; GSH; glutathione; MTX; methotrexate; LTC4; leukotriene C4; E217βG; 17β-estradiol 17β-(d-glucuronide); E13SO4; estrone 3-sulfate; NNAL; 4-(methylnitrosamino)1-(3-pyridyl)-1-butanol; DTT; dith