Keywords: EC ها، سلول های اندوتلیال; ASCs, adipose-derived stem cells; ECs, endothelial cells; vWF, von Willebrand factor
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Keywords: EC ها، سلول های اندوتلیال; Plasmodium; Innate immunity; Mononuclear phagocytesADCI, antibody-dependent cellular inhibition; CM, cerebral malaria; CT, cell traversal; DCs, dendritic cells; dLN, draining lymph node; E, erythrocyte; ECs, endothelial cells; EEF, exo-erythrocytic form;
Keywords: EC ها، سلول های اندوتلیال; ADMA, dimethylarginine; ECs, endothelial cells; ESAM, endothelial cell-selective adhesion molecule; ICAM-1, intercellular adhesion molecule 1; JAM, junction adhesion molecule; LDL, low density lipoprotein; MAdCAM-1, mucosal addressin cell adhesion molecul
Keywords: EC ها، سلول های اندوتلیال; CA, cerebral aneurysm; MMPs, matrix metalloproteinases; SMCs, smooth muscle cells; EPCs, endothelial progenitor cells; ECs, endothelial cells; ECFCs, endothelial colony-forming cells; MNCs, mononuclear cells; PBS, phosphate-buffered solution; DiI-acLDL, d
Keywords: EC ها، سلول های اندوتلیال; TSP, thrombospondin; EGF, epidermal growth factor like domains; SNP, single nucleotide polymorphism; ECs, endothelial cells; ECM, extracellular matrix; ES cell line, embryonic stem cell line; COMP, cartilage oligomeric matrix protein; GAG, glycosaminoglyc
Keywords: EC ها، سلول های اندوتلیال; Atherosclerosis; Artesunate; Inflammation; TNF-α; MCP-1ApoE, apolipoprotein e; WD, western-type diet; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; IL-8, interleukin-8; MCP-1, monocyte chemoattractant protein-1; ECs, endothelial cells; HUVECs, huma
Is insulin-like growth factor 1 (IGF-1) system an attractive target inflammatory bowel diseases? Benefits and limitation of potential therapy
Keywords: EC ها، سلول های اندوتلیال; AD, Alzheimer'sdisease; BMD, bone mineral density; CD, Crohn's disease; CRP, C-reactive protein; DM, diabetes mellitus; ECs, endothelial cells; eNOS, endothelial nitric oxide synthase; ERK 1/2, extracellular signal-regulated kinase 1/2; FFA, free fatty ac
Nicotinic acid inhibits NLRP3 inflammasome activation via SIRT1 in vascular endothelial cells
Keywords: EC ها، سلول های اندوتلیال; ASC, apoptosis-associated speck-like protein containing a CARD; ATP, adenosine triphosphate; CRP, C-reactive protein; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; IL, interleukin; LPS, lipopolysaccharide; MCP-1, monocyte chemota
MicroRNA-495 regulates the proliferation and apoptosis of human umbilical vein endothelial cells by targeting chemokine CCL2
Keywords: EC ها، سلول های اندوتلیال; CAD, coronary artery disease; CCK8, cell counting kit 8; Ct, threshold cycle; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; miRNAs, microRNAs; NC, negative control; qRT-PCR, quantitative RT-PCR; 3’ UTR, 3’ untranslated regionAthe
Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; GSI, γ-secretase inhibitor; Nox, NADPH oxidase; PTPs, phosphotyrosine phosphotases; DPI, diphenyl-iodide; NAC, N-acetylcysteine; DMSO, dimethyl sulfoxideNotch signaling; ROS; HUVECs;
γ-Irradiated cord blood MNCs: Different paracrine effects on mature and progenitor endothelial cells
Keywords: EC ها، سلول های اندوتلیال; BM, bone marrow; CB, cord blood; CB-MNCs, umbilical cord blood-derived MNCs; CM, conditioned medium; EBM2, endothelial basal medium; ECs, endothelial cells; ECFCs, endothelial-colony forming cells; EGF, epidermal growth factor; EGM2, endothelial complete
Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells
Keywords: EC ها، سلول های اندوتلیال; PCB2, procyanidin B2; NLRP3, NOD-like receptor family, pyrin domain containing 3; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; IL-1β, interleukin-1β; LPS, lipopolysaccharides; ROS, reactive oxygen species; AP-1, activator protei
β-Adrenoceptors differentially regulate vascular tone and angiogenesis of rat aorta via ERK1/2 and p38
Keywords: EC ها، سلول های اندوتلیال; β-ARs, β-adrenoceptors; CRCs, concentration–response curves; ECs, endothelial cells; ERK1/2, extracellular signal regulated kinase; FGF, fibroblast growth factor; MAPKs, mitogen activated protein kinases; NO, nitric oxide; PBS, phosphate buffered saline;
MicroRNA regulation of cancer metabolism: role in tumour suppression
Keywords: EC ها، سلول های اندوتلیال; ACL, ATP citrate lyase; CAT, catalase; CIV, complex IV; ECs, endothelial cells; ETC, electron transport chain; HIF, hypoxia-inducible factor; IDH, isocitrate dehydrogenase; IGF, insulin-like growth factor; IRS1, insulin receptor substrate-1; miRNA, microR
The disintegrin and metalloproteinase ADAM10 mediates a canonical Notch-dependent regulation of IL-6 through Dll4 in human endothelial cells
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; γSI, gamma-secretase inhibitor; SMCs, smooth muscle cells; NICD, Notch intracellular domain; MOI, multiplicity of infectionEndothelial cells; Inflammation; ADAM10; Notch pathway
Silicic acid in drinking water prevents age-related alterations in the endothelium-dependent vascular relaxation modulating eNOS and AQP1 expression in experimental mice: An immunohistochemical study
Keywords: EC ها، سلول های اندوتلیال; AQP-1, aquaporin-1; DAB, diaminobenzidine tetrahydrochloride; ECs, endothelial cells; eNOS, endothelial nitric oxide synthase; IOD, integrated optical density; NO, nitric oxide; Si, silicon; VSMCs, vascular smooth muscle cellsSilicon; Aorta; Kidney vessel
Crossing the wall: The opening of endothelial cell junctions during infectious diseases
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; BBB, blood brain barrier; CNS, central nervous system; VVO, vesicular vacuolar organelles; PECAM, platelet/endothelial cell adhesion molecule; ICAM, intracellular adhesion molecule; VCAM, vascular cell adhesion molecule; VEGF, vasc
The involvement of the monocytes/macrophages in chronic inflammation associated with atherosclerosis
Keywords: EC ها، سلول های اندوتلیال; LDL, low density lipoproteins; oxLDL, oxidized LDL; SMCs, smooth muscle cells; ECs, endothelial cells; TNF, tumor necrosis factor; IL, interleukin; M-CSF, macrophage colony stimulating factor; GM-CSF, granulocyte/macrophage colony stimulating factor; VCAM
Epicardial progenitor cells in cardiac regeneration and neovascularisation
Keywords: EC ها، سلول های اندوتلیال; (A)MI, (acute) myocardial infarction; BMSCs, bone marrow-derived haematopoietic stem cells; CPCs, cardiac progenitor cells; ECs, endothelial cells; (E)GFP, (enhanced) green fluorescent protein; EMT, epithelial to mesenchymal transition; EPDCS, epicardium-
Classification of mitocans, anti-cancer drugs acting on mitochondria
Keywords: EC ها، سلول های اندوتلیال; ANT, adenine nucleotide translocase; BH3, Bcl-2 homology-3; 3BP, 3-bromopyruvate; CI, complex I; DCA, dichloroacetate; 2DG, 2-deoxyglucose; ECs, endothelial cells; ETC, electron transport chain; G6P, glucose-6-phosphate; GSAO, 4-[N-(S-glutathionylacetyl)a
Src kinase-mediates androgen receptor-dependent non-genomic activation of signaling cascade leading to endothelial nitric oxide synthase
Keywords: EC ها، سلول های اندوتلیال; AR, androgen receptor; ARE, androgen-responsive element; ECs, endothelial cells; eNOS, endothelial nitric oxide synthase; PBS, phosphate buffered saline; PI3-kinase, phosphatidylinositol 3-kinase; testosterone-BSA, bovine serum albumin-coupled testosteron
Sepsis, thrombosis and organ dysfunction
Keywords: EC ها، سلول های اندوتلیال; APC, activated protein C; AT, antithrombin; DIC, disseminated intravascular coagulation; ECs, endothelial cells; EPCR, endothelial protein C receptor; HMGB-1, High Mobility Group Box-1; MODS, multiple organ dysfunction syndrome; PAI-1, plasminogen activat
Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats
Keywords: EC ها، سلول های اندوتلیال; SAH, subarachnoid hemorrhage; EBI, early brain injury; BBB, blood–brain barrier; ECs, endothelial cells; TJs, tight junctions; ZO-1, zonula occludens-1; Rock, Rho kinase; HF, hydroxyfasudil; ICA, internal carotid artery; PBS, phosphate-buffered saline; AN
Arterial shear stress augments the differentiation of endothelial progenitor cells adhered to VEGF-bound surfaces
Keywords: EC ها، سلول های اندوتلیال; VEGF, vascular endothelial cell growth factor; EPCs, endothelial progenitor cells; ECs, endothelial cells; MCs, mononuclear cells; PEVA, poly(ethylene-co-vinyl alcohol); HFIP, hexafluoroisopropanol; CDI, N,N′-carbonyl-diimidazoleVEGF; Endothelial progenit
Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells
Keywords: EC ها، سلول های اندوتلیال; Hcy, Homocysteine; HHcy, Hyperhomocysteinemia; HUVECs, Human umbilical vein endothelial cells; 5-aza-CdR, 5-aza-2′ deoxycytidine; 3-DZA, 3-deazadenosine; MSP, Methylation-specific PCR; ECs, Endothelial cells; PDGFs, Platelet-derived growth factors; VSMCs,
Atorvastatin preserves the integrity of endothelial adherens junctions by inhibiting vascular endothelial cadherin tyrosine phosphorylation
Keywords: EC ها، سلول های اندوتلیال; VE-cad, vascular endothelial cadherin; Tyr, tyrosine; ECs, endothelial cells; AJs, adherens junctions; IL-1β, interleukin-1β; MLC, myosin light chain; TEM, transendothelial migration; Pyk2, proline-rich tyrosine kinase 2; FPP, farnesyl pyrophosphate; GGPP
The arterial and cardiac epicardium in development, disease and repair
Keywords: EC ها، سلول های اندوتلیال; aPEO, arterial pro-epicardial organ; CMPCs, cardiomyocyte progenitor cells; ECs, endothelial cells; vPEO, venous pro-epicardial organ; VSMCs, vascular smooth muscle cellsCardiac development; Epicardium derived cells (EPDCs); Pericardium; Myocardial infarc
Inhibition of angiogenesis by S-adenosylmethionine
Keywords: EC ها، سلول های اندوتلیال; DNMT, DNA methyltransferase; EBM-2, endothelial basal medium; ECs, endothelial cells; EGM-2, endothelial growth medium; FBS, fetal bovine serum; HDAC, histone deacetylase; HUVEC, human umbilical vein endothelial cell; MTT, (3-(4,5-dimethyl-2-thiazolyl)-2,
Transcription factor COUP-TFII is indispensable for venous and lymphatic development in zebrafish and Xenopus laevis
Keywords: EC ها، سلول های اندوتلیال; COUP-TFII, Chicken Ovalbumin Upstream Promoter-Transcription Factor II; NR2F2, Nuclear Receptor 2F2; ECs, endothelial cells; vECs, venous ECs; LECs, lymphatic ECs; Fox, forkhead box; SoxF, SRY-related HMG box F; E, embryonic day; WISH, whole-mount in situ
Involvement of profilin-1 in angiotensin II-induced vascular smooth muscle cell proliferation
Keywords: EC ها، سلول های اندوتلیال; SHRs, spontaneously hypertensive rats; WKY, Wistar Kyoto rats; SBP, Systolic blood pressure; RASMCs, Rat aortic smooth muscle cells; VSMCs, vascular smooth muscle cells; Ang II, angiotensin II; ECs, endothelial cells; MTT, 3-(4,5-dim-ethylthiazol-2-yl)-2,
Cutaneous manipulation of vascular growth factors leads to alterations in immunocytes, blood vessels and nerves: Evidence for a cutaneous neurovascular unit
Keywords: EC ها، سلول های اندوتلیال; Ang1, angiopoietin; KCs, keratinocytes; VEGF, vascular endothelial growth factor; VEGFR2, vascular endothelial growth factor receptor 2; DNA, deoxyribonucleic acid; PCR, polymerase chain reaction; ECs, endothelial cells; CNU, cutaneous neurovascular unit;
Activating Notch signaling post-SCI modulates angiogenesis in penumbral vascular beds but does not improve hindlimb locomotor recovery
Keywords: EC ها، سلول های اندوتلیال; SCI, Spinal cord injury; ECs, endothelial cells; NICD, Notch intracellular domain; Jag, Jagged; Dll, Delta-like ligand; Hes, Hairy/Enhancer of Split; dpi, days post-injury; N1 Ab, anti-Notch1 antibody; Jag1-Fc, Jagged1-Fc chimeric protein; LEA, Lycopersic
Endothelial cells mediate the regeneration of hematopoietic stem cells
Keywords: EC ها، سلول های اندوتلیال; HSCs, hematopoietic stem cells; ECs, endothelial cells; BM, bone marrow
The effects of antimycin A on endothelial cells in cell death, reactive oxygen species and GSH levels
Keywords: EC ها، سلول های اندوتلیال; AMA, antimycin A; ECs, endothelial cells; CPAEC, calf pulmonary arterial endothelial cells; HUVEC, human umbilical vein endothelial cells; ROS, reactive oxygen species; MMP (ΔΨm), mitochondrial membrane potential; NADPH, nicotine adenine diphosphate; XO,
Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; TGF-beta1, transforming growth factor-beta1; OS, oxidative stress; ICAM-1, intercellular adhesion molecule-1; MCP-1, monocyte chemotactic protein-1Endothelial cell; ICAM-1; Macrophage migration; Oxidative stress; TGF-beta1; PKC-bet
American ginseng: Potential structure–function relationship in cancer chemoprevention
Keywords: EC ها، سلول های اندوتلیال; COX-2, cyclooxygenase-2; ECs, endothelial cells; IC50, 50% inhibitory concentration; MMP, matrix metalloproteinase; NF-κB, nuclear factor-κB; Pgp, P-glycoprotein; PPD, protopanaxadiol; PPT, protopanaxatriolAmerican ginseng; Panax quinquefolius; Asian gins
Anti-angiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells
Keywords: EC ها، سلول های اندوتلیال; ATC, anaplastic thyroid carcinoma; ECs, endothelial cells; VEGF, vascular endothelial growth factor; HUVECs, human umbilical vein endothelial cells; NF-κB, nuclear factor kappa B; uPA, urokinase-type plasminogen activator; FBS, fetal bovine serum; CBP, CR
Inflammation dysregulates Notch signaling in endothelial cells: Implication of Notch2 and Notch4 to endothelial dysfunction
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; HAECs, human arterial ECs; HUVECs, human umbilical vein ECs; ICD, intracellular domain; SMCs, smooth muscle cellsEndothelium; Inflammation; Notch; Cell signaling; Apoptosis; TNF
Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells
Keywords: EC ها، سلول های اندوتلیال; AU, arbitrary units; BMECs, bone marrow endothelial cells; di-LDL, diacetylated low-density lipoprotein; ECs, endothelial cells; EV, empty vector; FCS, fetal calf serum; hTERT, human telomerase reverse transcriptase; hTR, human telomerase RNA component; N
Total panax notoginsenosides prevent atherosclerosis in apolipoprotein E-knockout mice: Role of downregulation of CD40 and MMP-9 expression
Keywords: EC ها، سلول های اندوتلیال; apoE, apolipoprotein E; apoE-KO, apolipoprotein E-knockout; CD40, cell differentiation antigen 40; ECs, endothelial cells; IL, interleukin; LDL-C, low density lipoprotein cholesterol; MMP-9, matrix metalloproteinase 9; MФ, macrophages; oxLDL, oxidized low
Endothelial cells promote the proliferation of lymphocytes partly through the Wnt pathway via LEF-1
Keywords: EC ها، سلول های اندوتلیال; ECs, endothelial cells; LEF-1, lymphoid enhancer factor 1; HGM, highly mobility group; TCF, T-cell factorLEF-1; Endothelial cell; Lymphocyte; Proliferation; Apoptosis
The role of platelets CD40 ligand (CD154) in acute coronary syndromes
Keywords: EC ها، سلول های اندوتلیال; ACS, Acute coronary syndrome; ECs, endothelial cells; SMCs, smooth muscle cells; CD40L, CD40 ligand; CAD, coronary artery disease; AMI, acute myocardial infarction; UA, unstable angina; SA, stable angina; BMI, body mass index; WHR, waist hip ratio; SWMSI,
Coagulation dysregulation as a barrier to xenotransplantation in the primate
Keywords: EC ها، سلول های اندوتلیال; AHXR, acute humoral xenograft rejection; CC, consumptive coagulopathy; ECs, endothelial cells; fgl-2, fibrinogen-like protein 2; Gal, Gal α 1,3 Gal; GT-KO, α1,3-galactosyltransferase gene knocked out; HAR, hyperacute rejection; hCRP, human complement regu
Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: An in vitro study
Keywords: EC ها، سلول های اندوتلیال; BBB, blood-brain barrier; BSA, bovine serum albumin; ECs, endothelial cells; GCs, glial cells; OGD, oxygen glucose deprivation; PBS, phosphate-buffered saline; Pe, endothelial permeability coefficient; tPA, tissue plasminogen activatorBlood-brain barrier;
Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia
Keywords: EC ها، سلول های اندوتلیال; blood–brain barrier; stroke; gelatinases; stromelysin-1; extracellular matrix; MMP inhibitorsBBB, blood–brain barrier; BL, basal lamina; COX, cyclooxygenase; CSF, cerebrospinal fluid; ECs, endothelial cells; HIF-1α, hypoxia inducible factor-1α; IL-1β, int
Opposing actions of Notch1 and VEGF in post-natal cardiac valve endothelial cells
Keywords: EC ها، سلول های اندوتلیال; EMT, endothelial-to-mesenchymal transformation; ECs, endothelial cells; VICs, valve interstitial cells; EBM, endothelial cell basal medium; TGF-β, transforming growth factor-β; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor
Olmesartan blocks advanced glycation end products (AGEs)-induced angiogenesis in vitro by suppressing receptor for AGEs (RAGE) expression
Keywords: EC ها، سلول های اندوتلیال; PDR, proliferative diabetic retinopathy; AGEs, advanced glycation end products; RAGE, receptor for AGEs; VEGF, vascular endothelial growth factor; TNF-α, tumor necrosis factor-α; ECs, endothelial cells; BSA, bovine serum albumin; RT-PCR, reverse transcrip
Resistance to anti-xenogeneic response by combining α-Gal silencing with HO-1 upregulation
Keywords: EC ها، سلول های اندوتلیال; α1,3GT, α1,3-galactosyltransferase; α-Gal, Galα(1,3)Gal; CDC, complement dependent cytotoxicity; ECs, endothelial cells; FACS, fluorescence activated cell sorter; FCS, fetal calf serum; GS-IB4, griffonia simplicifolia isolectin B4; HINHS, heat-inactivated
Possibilities and potential roles of estrogen in the pathogenesis of proliferation hemangiomas formation
Keywords: EC ها، سلول های اندوتلیال; MMP-9, matrix metalloproteinase-9; sKitL, soluble Kit-ligand; VEGF, vascular endothelial growth factor; NO, nitric oxide; eNOS, endothelial nitric oxide synthase; EPCs, endothelial progenitor cells; HSCs, haematopoietic stem cells; ECs, endothelial cells;
Arterial–venous endothelial cell fate is related to vascular endothelial growth factor and Notch status during human bone mesenchymal stem cell differentiation
Keywords: EC ها، سلول های اندوتلیال; hMSCs, human bone mesenchymal stem cells; MSCs, mesenchymal stem cells; ECs, endothelial cells; VEGF, vascular endothelial growth factor; vWF, von Willebrand factorEndothelial cell; Mesenchymal stem cell; Arteries; Veins