Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; Isolated endothelial cells; Chronic exercise; RatCellules endothéliales isolées; Exercice chronique; RatAch, Acetylcholine; BH4, Tetrahydrobiopterin; ED, Endothelial Dysfunction; EDHF, Endothelium-Derived Hyperpolarizing Factor; eNOS, NO Synthase Endothel
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Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; AR, adenosine receptor; COX, cycloxygenase; DPCPX, 8-cyclopentyl-1,3-dipropylxanthine; DMSO, dimethyl sulphoxide; EDHF, endothelium-derived hyperpolarizing factor; KO, knockout; NS398, N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide; Ozagrel, (E)-3
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; Chlorogenic acid; Vasorelaxation; Endothelial pathways; Toxicitycga, chlorogenic acid; L-name, nω-nitro-l-arginine methyl ester; Ach, acetylcholine; No, nitric oxide; NOS, NO synthase; COX, cyclooxygenase; EDHF, endothelium-derived hyperpolarizing factor
NO synthase inhibition attenuates EDHF-mediated relaxation induced by TRPV4 channel agonist GSK1016790A in the rat pulmonary artery: Role of TxA2
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; ACh, acetylcholine; ANOVA, analysis of variance; EDHF, endothelium-derived hyperpolarizing factor; GSK, GSK1016790A; ICI192605, [4-(Z)-6-(2-0-chlrophenyl-4-Ohydroxyphenyl-1,3-dioxan-cis5-yl) hexenoic acid]; IKCa (KCa3.1), intermediate conductance potassiu
Uridine adenosine tetraphosphate is a novel vasodilator in the coronary microcirculation which acts through purinergic P1 but not P2 receptors
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; 8PT, 8-phenyltheophylline; COX, cycloxygenase; CYP 2C9, cytochrome P450 2C9; DMSO, dimethyl sulfoxide; EDHF, endothelium-derived hyperpolarizing factor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LNAME, Nω-nitro-l-arginine methyl ester HCl; NOS, nit
Flow (shear stress)-mediated remodeling of resistance arteries in diabetes
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; EDHF, endothelium-derived hyperpolarizing factor; FMD, flow-mediated dilation; NO, nitric oxide; ROS, reactive oxygen species; ONOO-, peroxinitrite anion; eNOS, endothelial NO-synthase; FMD, flow-mediated dilation; MMPs, metalloproteases; ECM, extracellul
NO and EDHF pathways in pulmonary arteries and veins are impaired in COPD patients
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; COPD, chronic obstructive pulmonary disease; EDHF, endothelium-derived hyperpolarizing factor; Indo, indomethacin; L-NNA, NG-nitro-l-arginine; NO, nitric oxide; eNOS, nitric oxide synthase; HbO, oxyhemoglobin; PMSF, phenylmethylsulfonyl fluoride; p-eNOS,
Role of inflammation in the regulation of coronary blood flow in ischemia and reperfusion: Mechanisms and therapeutic implications
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; 5-HT, serotonin; ACEI, angiotensin converting enzyme inhibitor; ACh, acetylcholine; AMI, acute myocardial infarction; CAD, coronary artery disease; CBF, coronary blood flow; CNP, C-type natriuretic peptide; EDHF, endothelium-derived hyperpolarizing factor
Endothelium-dependent nitroxyl-mediated relaxation is resistant to superoxide anion scavenging and preserved in diabetic rat aorta
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; ACh, acetylcholine; AS, Angeli's salt; 4-AP, 4-aminopyridine; BH4, tetrahydrobiopterin; cGMP, cyclic guanosine monophosphate; DEA, DEANONOate; DPI, diphenylene iodonium; EA, ethacrynic acid; EDHF, endothelium-derived hyperpolarizing factor; eNOS, endothel
Nitrite- and nitroxyl-induced relaxation in porcine coronary (micro-) arteries: Underlying mechanisms and role as endothelium-derived hyperpolarizing factor(s)
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; 4-AP, 4-aminopyridine; CRC, concentration–response curve; DEA-NONOate, diethylamine NONOate; EDHF, endothelium-derived hyperpolarizing factor; eNOS, endothelial NO synthase; IKCa/SKCa, intermediate-conductance and small-conductance Ca2+-activated K+-chann
The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; BKCa channels, large-conductance calcium- and voltage-activated potassium channels; EDHF, endothelium-derived hyperpolarizing factor; eNOS, endothelial nitric oxide synthase; ER, estrogen receptor; ERK, extracellular signal-related kinase; GPER, G protein
The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases ✩
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; AA, arachidonic acid; CYP, cytochrome P450; EETs, epoxyeicosatrienoic acids; HETEs, hydroxyeicosatetraenoic acids; DHETs, dihydroxyeicosatrienoic acids; EDHF, endothelium-derived hyperpolarizing factor; tPA, tissue plasminogen activator; cAMP, cyclic AMP;
Procyanidin-rich fractions from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endothelium-dependent relaxation involving NO and EDHF in porcine coronary artery
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; NO, Nitric oxide; EDHF, Endothelium-derived hyperpolarizing factor; l-NA, Nω-nitro-l-arginine; CTX, Charybdotoxin; APA, Apamin; SOD, Superoxide dismutase; GAE, Gallic acid equivalentParkia biglobosa (Mimosaceae); Polyphenols; Procyanidins; Vasorelaxant; C
Cellular electrophysiologic and mechanical evidence of superior vascular protection in pulmonary microcirculation by Perfadex compared with Celsior
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; BK, bradykinin; CI, confidence interval; EC, Euro-Collins; EDHF, endothelium-derived hyperpolarizing factor; HbO, oxyhemoglobin; Indo, indomethacin; L-NNA, N-nitro-L-arginine; NNONPG, non-nitric oxide and non-prostacyclin; NO, nitric oxide; PGI2, prostacy
Prostanoids and reactive oxygen species: Team players in endothelium-dependent contractions
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; ADP, adenosine diphosphate; cAMP, cyclic adenosine monophosphate; COX, cyclooxygenase; DETCA, diethyldithiocarbamic acid; EDCF, endothelium-derived contracting factor; EDHF, endothelium-derived hyperpolarizing factor; EDRF, endothelium-derived relaxing fa
Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; Ach, acetylcholine; BKCa, large-conductance calcium-activated potassium channels; EDHF, endothelium-derived hyperpolarizing factor; Emax, maximum effect elicited by the agonist; IKCa, intermediate calcium-activated potassium channels; KCa, calcium-activat
Inflammatory cytokines in vascular dysfunction and vascular disease
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; AAA, abdominal aortic aneurysm; AngII, angiotensin II; BP, blood pressure; CSF, colony stimulating factors; CRP, C-reactive protein (CRP); ECM, extracellular matrix; EC, endothelial cell; EDHF, endothelium-derived hyperpolarizing factor; ET-1, endothelin;
Role of the Endothelium in the Vascular Effects of the Thrombin Receptor (Protease-Activated Receptor Type 1) in Humans
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; ANOVA, analysis of variance; EDHF, endothelium-derived hyperpolarizing factor; L-NMMA, L-NG-monomethyl arginine citrate; NO, nitric oxide; PAI-1, plasminogen activator inhibitor type 1; PAR, protease-activated receptor; PGI2, prostacyclin; SNP, sodium nit
Vascular adaptation of the internal thoracic artery graft early and late after bypass surgery
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; CABG, coronary artery bypass grafting; CFR, coronary flow reserve; EDHF, endothelium-derived hyperpolarizing factor; ITA, internal thoracic artery; LAD, left anterior descending coronary artery; LV, left ventricular; NO, nitric oxide; SVG, saphenous vein
Impaired cAMP signaling does not account for the attenuated EDHF-mediated dilations in female rat middle cerebral artery
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; EC, endothelial cell; EDHF, endothelium-derived hyperpolarizing factor; MCA, middle cerebral artery; PSS, physiological salt solution; SMC, smooth muscle cellcAMP; Endothelium-derived hyperpolarizing factor; Gender; Rat; Vascular smooth muscle
Important Role of Endogenous Hydrogen Peroxide in Pacing-Induced Metabolic Coronary Vasodilation in Dogs In Vivo
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; CBF, coronary blood flow; DAR, diaminorhodamine-4M AM; DCF, 2′,7′-dichlorodihydrofluorescein diacetate; EDHF, endothelium-derived hyperpolarizing factor; H2O2, hydrogen peroxide; L-NMMA, NG-monomethyl-L-arginine; LAD, left anterior descending coronary art
Tamoxifen and estrogen attenuate enhanced vascular reactivity induced by estrogen deficiency in rat carotid arteries
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; CCA, common carotid artery; CTX, charybdotoxin; EDHF, endothelium-derived hyperpolarizing factor; HRT, hormone replacement therapy; IBX, iberiotoxin; l-NNA, NG-nitro-l-arginine; NO, nitric oxide; NOS, nitric oxide synthase; Ovx, ovariectomy or ovariectomi
Identification of a Cytochrome P450 2C9-Derived Endothelium-Derived Hyperpolarizing Factor in Essential Hypertensive Patients
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; ACH, acetylcholine; BDK, bradykinin; BP, blood pressure; COX, cyclooxygenase; CYP 2C, cytochrome P450 epoxygenase; EDHF, endothelium-derived hyperpolarizing factor; EET, epoxyeicosatrienoic acid; FBF, forearm blood flow; L-NMMA, NG-monomethyl-L-arginine;
Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; TNP-ATP, 2,4,6-trinitrophenyl (TNP)-ATP; EETs, epoxyeicosatrienoic acids; EDHF, endothelium-derived hyperpolarizing factor; GST, glutathione-S-transferase; AA, arachidonic acid; DHET, 11,12-dihydroxyeicosatrienoic acid; PIP2, phosphatidylinositol 4,5-bisp
Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response
Keywords: EDHF، فاکتور هیپرپولاریزاسیون حاصل از اندوتلیوم; 17-ODYA, 17-octadecynoic acid; ACh, acetylcholine; BKCa, large-conductance Ca2+-activated K+ channel; ChTX, charybdotoxin; COX, cyclooxygenase; EDCF, endothelium-derived contracting factor; EDHF, endothelium-derived hyperpolarizing factor; EDRF, endotheli