
Keywords: ELISpot، آنزیم مرتبط ایمنی ایمپکت; ELISpot, enzyme-linked immunospot assay; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; IFNγ, interferon γ; IL5, interleukin 5; PBMC, peripheral blood mononuclear cells; SFC, spot forming cells; Th1, T helper 1; Th2, T helper 2Hepatitis B vac