Keywords: آندومورفین 2; DOP; δ opioid receptor; EM-1; endomorphin-1; EM-2; endomorphin-2; i.c.v.; intracerebroventricular; i.p.; intraperitoneal; i.t.; intrathecal; KOP; κ opioid receptor; MOP; μ opioid receptor; MPE; maximum possible effect; s.c.; subcutaneous; Spinal antino
مقالات ISI آندومورفین 2 (ترجمه نشده)
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Keywords: آندومورفین 2; BBB; blood-brain barrier; Boc; tert-butyloxycarbonyl; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DAMGO; H-Tyr-d-Ala-Gly-NMePhe-Gly-ol; DCM; dichloromethane; DIEA; N,N-diisopropylethylamine; DOR; δ-opioid receptor; DPDPE; Tyr-c(d
Keywords: آندومورفین 2; β-FNA; β-funaltrexamine; ANOVA; analysis of variance; CIBP; Cancer-induced bone pain; DRG; dorsal root ganglion; EM2; endomorphin-2; EM2-IP; EM2-immunopositive; MOR; μ opioid receptor; PB; phosphate buffer; PBS; phosphate-buffered saline; POD; post-ope
Keywords: آندومورفین 2; AgOTf; silver triflate; BBB; blood-brain barrier; CDMT; 2-chloro-4,6-bis[3-(perfluorohexyl)propyloxy]-1,3,5-triazine; CNS; central nervous system; DMF; dimethylformamide; EM-2; endomorphin-2; Fmoc; N-(9-fluorenylmethyloxycarbonyl); GPI assay; guinea pig
Keywords: آندومورفین 2; Enzymatic synthesis; Organic solvent stable protease; Endomorphin-2; Thermodynamic control; In situ product removal;
Novel peptide inhibitor of dipeptidyl peptidase IV (Tyr-Pro-D-Ala-NH2) with anti-inflammatory activity in the mouse models of colitis
Keywords: آندومورفین 2; AMC; aminomethylcoumarin; CD; Crohn's disease; DIP; diprotin; DMSO; dimethyl sulfoxide; DPP; IV dipeptidyl peptidase IV; DSS; dextran sulfate sodium; EM-2; endomorphin-2; GAPDH; glycerylaldehyde-3-phosphate dehydrogenase; GI; gastrointestinal; GLP-1; gl
Cyclopeptide Dmt-[D-Lys-p-CF3-Phe-Phe-Asp]NH2, a novel G protein-biased agonist of the mu opioid receptor
Keywords: آندومورفین 2; EM-2; endomorphin-2; DPP IV; dipeptydyl peptidase IV; BRET assay; bioluminescence resonance energy transfer assay; Opioid receptors; Opioid peptides; Biased analogs; G protein-coupled receptors; β-Arrestins; Bioluminescence resonance energy transfer assa
Cardiovascular and respiratory activity of PK20, opioid and neurotensin hybrid peptide in anesthetized and awake rats
Keywords: آندومورفین 2; Hybrid peptide; Neurotensin; Endomorphin-2; Cardiorespiratory effects; Analgesic chimera;
Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues
Keywords: آندومورفین 2; BU72; 17-methyl-3-hydroxy-[5β,7β,3â²,5â²]-pyrrolidino-2â²[S]-phenyl-7α-methyl-6,14-endoetheno morphinan; CHO; Chinese hamster ovary; DPDPE; [D-Ala2-N-Me-Phe4-Gly-ol] enkephalin; EM-2; endomorphin-2; NMe; N-methyl; Opioid receptors; N-Methylated amin
Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance
Keywords: آندومورفین 2; Chimeric peptide; Endomorphin-2; Neuropeptide FF; Opioid; Antinociception; Non-tolerance; ANOVA; analysis of variance; AUC; area under the curve; β-FNA; beta-Funaltrexamine; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; CPA; conditio
Endomorphin-1 analogues (MELs) penetrate the blood-brain barrier and exhibit good analgesic effects with minimal side effects
Keywords: آندومورفین 2; Antinociception; Blood-brain barrier; Constipation; Endomorphin; Tolerance; BBB; bloodâbrain barrier; cAMP; cyclic adenosine monophosphate; CCI; chronic constriction injury; CNS; central nervous system; DOR; δ opioid receptor; EM-1; endomorphin-1; EM
Role of neurotensin and opioid receptors in the cardiorespiratory effects of [Ile9]PK20, a novel antinociceptive chimeric peptide
Keywords: آندومورفین 2; Hybrid peptide; Neurotensin; Endomorphin-2; Cardio-respiratory effects; Analgesic chimeraArg, arginine; Dmt, dimethyl-tyrosine; f, frequency of breathing; i.p., intraperitoneal injection; i.v., intravenous injection; Ile9, isoleucine9; MAP, mean arterial
Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity
Keywords: آندومورفین 2; Endomorphin-2; Opioid; Dmt; Analgesics;
Research reportNeuropeptide FF attenuates the acquisition and the expression of conditioned place aversion to endomorphin-2 in mice
Keywords: آندومورفین 2; CNS; central nervous system; CPA; conditioned place aversion; CPP; conditioned place preference; Dyn; dynorphin A (1-17); EM-1; endomorphin-1; EM-2; endomorphin-2; NAc; nucleus accumbens; NPFF; neuropeptide FF; MOP; mu-opioid; KOP; kappa-opioid; VTA; ve
Effect of potent endomorphin degradation blockers on analgesic and antidepressant-like responses in mice
Keywords: آندومورفین 2; Endomorphin-1; Endomorphin-2; Enzymatic hydrolysis; μ-Opioid receptors; Analgesic effect; Antidepressant-like effect;
The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro
Keywords: آندومورفین 2; Endomorphin-1; Endomorphin-2; Deltorphin I; Angiogenesis; HUVEC
Effects of transgene-mediated endomorphin-2 in inflammatory pain
Keywords: آندومورفین 2; Inflammatory pain; Opiates; Endomorphin-2; Gene therapy; Herpes simplex virus;
In vitro and in vivo characterization of opioid activities of C-terminal esterified endomorphin-2 analogs
Keywords: آندومورفین 2; Endomorphin-2; C-terminal esterified analogs; Colonic contraction; Cardiovascular response; Antinociception
Characteristic fragmentation behavior of the analogs of endomorphin-2 with phenylglycine in position 3 or 4 by ESI-FT tandem mass spectrometry
Keywords: آندومورفین 2; Endomorphin-2; Opioid peptide analogs; Phenylglycine; ESI-FT MS;
Endogenous opioid peptides, endomorphin-1 and -2 and deltorphin I, stimulate angiogenesis in the CAM assay
Keywords: آندومورفین 2; Endomorphin-1; Endomorphin-2; Deltorphin I; Angiogenesis; CAM
Role of GABAB receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats
Keywords: آندومورفین 2; GABAB receptor; Nucleus accumbens; Dopamine efflux; Endomorphin-1; Endomorphin-2; (Rat)
Role of GABAA receptors in the endomorphin-1-, but not endomorphin-2-, induced dopamine efflux in the nucleus accumbens of freely moving rats
Keywords: آندومورفین 2; GABAA receptor; Nucleus accumbens; Dopamine efflux; Endomorphin-1; Endomorphin-2; (Rat)
Structure-activity study of endomorphin-2 analogs with C-terminal modifications by NMR spectroscopy and molecular modeling
Keywords: آندومورفین 2; Endomorphin-2; C-terminal modification; Conformation; NMR spectroscopy; Molecular modeling;
Structure–activity relationships of modified C-terminal endomorphin-2 analogues by molecular dynamics simulations
Keywords: آندومورفین 2; Endomorphin-2; Structure–activity-relationship; AM1 calculations; Molecular dynamics simulation; Rotamer-combination approach
Conformational analysis of endomorphin-2 analogs with phenylalanine mimics by NMR and molecular modeling
Keywords: آندومورفین 2; Endomorphin-2; Conformation; NMR; Molecular modeling;
Opioid receptor binding and antinociceptive activity of the analogues of endomorphin-2 and morphiceptin with phenylalanine mimics in the position 3 or 4
Keywords: آندومورفین 2; Endomorphin-2; Morphiceptin; Phenylalanine mimics; Structure–activity relationships; Opioid peptide analogues
Structure-activity relationships of novel endomorphin-2 analogues with N-O turns induced by α-aminoxy acids
Keywords: آندومورفین 2; Endomorphin-2; Opioid peptide; N-O turn; α-Aminoxy acid; Simulation;
Structure-activity relationship of the novel bivalent and C-terminal modified analogues of endomorphin-2
Keywords: آندومورفین 2; Endomorphin-2; Dimerization; Modification; Structure-activity relationship; Opioid peptide;
Effects of synchronous or asynchronous electroacupuncture stimulation with low versus high frequency on spinal opioid release and tail flick nociception
Keywords: آندومورفین 2; Endomorphin-2; Dynorphin; Acupuncture; Electroacupuncture stimulation; Opioids; Synergy;
Reduced suppression of CO2-induced ventilatory stimulation by endomorphins relative to morphine
Keywords: آندومورفین 2; Neurotransmitters, modulators, transporters, and receptors; Opioids: anatomy, physiology, and behavior; EM1; endomorphin-1; EM2; endomorphin-2; DAMGO; Tyr-d-Ala-Gly-MePhe-Gly-ol; MS; morphine sulfate; HCVR; hypercapnic ventilatory response; MOR; mu-opioid
Mu-opioid receptor is present in dendritic targets of Endomorphin-2 axon terminals in the nuclei of the solitary tract
Keywords: آندومورفین 2; endogenous opioid; extrasynaptic receptors; pain; electron microscopy; confocal microscopy; BDA; biotinylated dextran amine; BSA; bovine serum albumin; Endo2; Endomorphin-2; ir; immunoreactive/immunoreactivity; MOR; mu-opioid receptor; MOR1; cloned mu-opi