Keywords: Genotoxicity; Isoquercitrin; Enzymatically-modified isoquercitrin; Flavonol; DNA damage; Food additive; AGIQ; alpha-glycosyl isoquercitrin; CGTase; cyclodextrin glucanotransferase; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EFSA; Eur
مقالات ISI (ترجمه نشده)
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Keywords: 5-HTT; serotonin transporter; AA; active avoidance; CS; conditioned stimulus; PTSD; posttraumatic stress disorder; MD; major depression; 5-HTTLPR; serotonin transporter linked polymorphic region; ENU; ethyl-N-nitrosurea; Serotonin transporter gene; Stress
Keywords: AAV; adeno-associated virus; Arx; aristaless-related homeobox; BA; biliary atresia; BAC; bacterial artificial chromosome; BDL; bile duct ligation; CD; campomelic dysplasia; CDE; choline-deficient ethionine-supplemented diet; Cdx2; caudal type homeobox 2;
Keywords: AdoMet; S-adenosylmethionine; DHF; dihydrofolate; DHFR; DHF reductase; ENU; ethylnitrosourea; ESTR; Expanded Simple Tandem Repeat; FA; folic acid; MTHFR; 5,10-methylenetetrahydrofolate reductase; MN; micronucleus; CD24-; Pig-a mutant phenotype; NCE; normo
Keywords: High hydrostatic pressure; Rice; Mutagenesis; DNA strand damage; DMN; dimethylnitrosamine; HHP; high hydrostatic pressure; SDW; sterile distilled water; LMA; low-melting agarose; NMA; normal-melting agarose; ENU; ethylnitrosourea; UV; ultraviolet;
Leaves of Acer palmatum thumb. Rescues N-ethyl-N-nitrosourea (ENU)-Induced retinal degeneration in mice
Keywords: Retinal degeneration; Photoreceptor cell death; Acer palmatum thunb; N-ethyl-N-Nitrosourea (ENU); Herbal medicine; Anti-cell death effect; KIOM-2015E; Acer palmatum thumb.ethanol extract; ENU; N-ethyl-N-nitrosourea; RP; retinitis pigmentosa; AMD; age-rela
Developmental and extrahepatic physiological functions of SREBP pathway genes in mice
Keywords: AAV; adeno-associated virus; ACC; acetyl-CoA carboxylase; AD; Alzheimer's disease; ADD1; adipocyte determination- and differentiation-dependent factor 1; APP; amyloid precursor protein; Api6; apoptosis inhibitor 6; ApoE; apolipoprotein E; ATF6; activati
Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction
Keywords: Sulfogalactosylglycerolipid; Seminolipid; Lipidomics; Mass spectrometry; Lipid rafts; Male reproduction; Male fertility; APMs; anterior head plasma membrane vesicles; ARSA; arylsulfatase A; CGT; ceramide galactosyltransferase; CHO; Chinese hamster ovary c
IL-3 and GM-CSF modulate functions of splenic macrophages in ENU induced leukemia
Keywords: IL-3; interleukin-3; GM-CSF; granulocyte macrophage-colony stimulating factor; ENU; Nâ²-ethyl-Nâ²-nitrosourea; NO; nitric oxide; MCP-1; monocyte chemoattractant protein-1; IFN-γ; interferon-gamma; iNOS; inducible nitric oxide synthase; TLR-2; Toll-like
A point mutation in the extracellular domain of CD4 completely abolishes CD4 T cell development in C57BL/6 mouse
Keywords: CD4; T cell; Enu; Point mutation; Adoptive transfer;
Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance
Keywords: FFAR1/GPR40; Free fatty acids; Insulin secretion; ENU-mutated Ffar1; FFAR1 deficient mice; High fat diet; CD; regular chow diet; ENU; N-ethyl-N-nitrosourea; FFAR1; free fatty acid receptor 1; GIIS; glucose-induced insulin secretion; GLP-1; glucagon like p
Pyrene did not induce gene mutation in red blood cell Pig-a assay and PIGRET assay in rats
Keywords: Pyrene; Pig-a gene; Gene mutation; Red blood cells; Reticulocytes; %RET; percent of reticulocytes; APC; allophycocyanin; ENU; ethylnitrosourea; FITC; fluorescein isothiocyanate; GPI; glycosylphosphatidylinositol; JEMS; Japanese environmental mutagen socie
Red blood cell Pig-a assay and PIGRET assay in rats with azathioprine
Keywords: %RET; percent of reticulocytes; 6-MP; 6-mercaptopurine; APC; allophycocyanin; Aza; azathioprine; ENU; ethylnitrosourea; FITC; fluorescein isothiocyanate; GPI; glycosylphosphatidylinositol; HPRT; hypoxanthine-guanine phosphoribosyltransferase; IARC; intern
Evaluation of the PIGRET assay as a short-term test using a single dose of diethylnitrosamine
Keywords: Pig-a; phosphatidylinositol glycan complementation group A; DEN; diethylnitrosamine; ENU; N-ethyl-N-nitrosourea; MF; mutant frequency; RBC; red blood cell; RET; reticulocyte; Collaborative study in Japan; RBC Pig-a assay; PIGRET assay; Diethylnitrosamine;
Evaluation of mutagenicity of acrylamide using RBC Pig-a and PIGRET assays by single peroral dose in rats
Keywords: %RET; percent of reticulocyte; AA; acrylamide; APC; allophycocyanin; ENU; N-ethyl-N-nitrosourea; FITC; fluorescein isothiocyanate; GA; glycidamide; GPI; glycosylphosphatidylinositol; HSC; hematopoietic stem cell; JEMS; the Japanese Environmental Mutagen S
GnaqM1J: An ENU-Induced Mutant Allele Affecting Pigmentation in the Mouse
Keywords: ENU; N-ethyl-N-nitrosourea; Gnaq; guanine nucleotide binding protein alpha q polypeptide; M1J; Mutation 1 Jackson;
Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents
Keywords: AAG; alkyladenine DNA glycosylase; ATM; ataxia telangiectasia mutated; BER; base excision repair; BPD; break point dose; BMD; benchmark dose; BMDL; benchmark dose lower confidence limit; CSBP; computational systems biology pathway; DSB; double strand brea
Cytotoxic activity of T lymphocytes is induced upon stimulation with IL-3 plus GM-CSF in animal leukemia model
Keywords: ENU; N-ethyl-Nâ²-nitrosourea; rmIL-3; recombinant mouse interleukin-3; rmGM-CSF; recombinant mouse granulocyte-macrophage colony-stimulating factor; RT-PCR; real time polymerase chain reaction; PTK; protein tyrosine kinase; IFN-γ; interferon gamma; Leuk
Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles
Keywords: Single cell transcriptogenomics; ENU; Germline mutations; Somatic mutations; Next generation sequencing; Allelic exclusion;
Kinetics of micronucleus induction and cytotoxicity caused by distinct antineoplastics and alkylating agents in vivo
Keywords: MN-PCE; micronucleated polychromatic erythrocytes; aza-C; 5-aza-cytidine; BCNU; bis-chloroethyl-nitrosourea; BUS; busulfan; COL; colchicine; CP; cyclophosphamide; DMN; dimethylnitrosamine; ENU; ethylnitrosourea; MMC; mitomycin C; MNU; methylnitrosourea; V
Attenuation of mania-like behavior in Na+,K+-ATPase α3 mutant mice by prospective therapies for bipolar disorder: Melatonin and exercise
Keywords: ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; EDTA; ethylenediaminetetraacetic acid; EEG; electroencephalographic; ELISA; enzyme-linked immunosorbent assay; EMG; electromyographic; ENU; N-ethyl-N-nitrosourea; EPM; elevated plus maz
No evidence for transgenerational genomic instability in the F1 or F2 descendants of Mutaâ¢Mouse males exposed to N-ethyl-N-nitrosourea
Keywords: ENU; N-ethyl-N-nitrosourea; ESTR; expanded simple tandem repeat; MN; micronuclei; TGI; transgenerational genomic instability; Mouse; Germline; Mutation; Micronuclei;
Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich GckD217V mutants
Keywords: Maturity-onset diabetes of the young, Neonatal diabetes; Glucokinase; β-cell dysfunction; ENU; Experimental genetics
Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development
Keywords: Hpr; hypophosphatemic rickets; SAXS; small angle X-ray scattering; LB; lateral border; IF; infraspinous fossa; ENU; N-ethyl-N-nitrosourea; PBS; phosphate buffered saline; Ï; predominant direction of orientation; Ï; degree of orientation; N-ethyl-n-nitro
Characterization of a novel missense mutation on murine Pax3 through ENU mutagenesis
Keywords: White spotting; Neural tube defect; ENU; Pax3; Transactivation
ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans
Keywords: BLAST; Basic Local Alignment Search Tool; DCC; deleted in colorectal cancer; DNC; dorsal nerve cord; Dpy; dumpy; DTC; distal tip cell; Egl; egg laying defective; Enu; enhancer of Unc; Fra; frazzled; GFP; green fluorescent protein; myo; myosin heavy chain
In vivo studies in the mouse to define a threshold for the genotoxicity of EMS and ENU
Keywords: EMS; ENU; In vivo genotoxicity; Dose response; Threshold; Risk assessment
Evaluation of Macaca mulatta as a model for genotoxicity studies
Keywords: Rhesus monkey; Mutation; ENU; HPRT; PIG-A; Cloning; Flow cytometry; Lymphocytes; Erythrocytes
Forward genetic analysis of TLR-signaling pathways: An evaluation
Keywords: ENU; Mutagenesis; TLR; Innate immunity
Fresh and frozen–thawed sperm quality, nuclear DNA integrity, invitro fertility, embryo development, and live-born offspring of N-ethyl-N-nitrosourea (ENU) mice
Keywords: Mouse; Spermatozoa; DNA integrity; Cryopreservation; Fertility; Embryo; ENU; Mutation
An ENU-induced mutation in the lymphotoxin α gene impairs organogenesis of lymphoid tissues in C57BL/6 mice
Keywords: Lymph organogenesis; Lymph node; Spleen; Marginal zone; Leukocytosis; B1b; Bone marrow; Thymus; ENU;
Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis
Keywords: N-ethyl-N-nitrosourea mutagenesis; immunodeficiency; Zap70; IgE; rodents; B6; C57BL/6JIco; C3H; C3HeB/FeJ; ENU; N-ethyl-N-nitrosourea; LAT; Linker for activation of T cells; NK; Natural killer; PLC; Phospholipase C; OVA; Ovalbumin; TCR; T-cell receptor; W
A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud
Keywords: cis-regulatory element; MFCS1; Sonic hedgehog; Noncoding sequence; ENU; Mutagenesis; Single nucleotide polymorphism; Limb development; Axis formation
A single-molecule PCR approach to the measurement of induced expanded simple tandem repeat instability in vitro
Keywords: Mouse cell culture; Single-molecule PCR; ENU; Tandem repeat instability; ESTR
Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay
Keywords: Mutagenesis; Mutation; Mutation assay; Flow cytometry; CD59; CHO AL; Radiation; MNNG; EMS; UV; ENU; Benzo(a)pyrene; Chlorpheniramine maleate; Ethidium bromide; Hydrogen peroxide; Lead; Mitomycin C; Arsenic; Thalidomide; Tetrachloroethane; Asbestos; Colchi
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid
Keywords: Murine cell line; Mutation; Cell culture; Etoposide; ENU; Okadaic acid; Benzo(a)pyrene; Expanded simple tandem repeat; DNA instability; Single-molecule-PCR;
Animal carcinogenicity studies on radiofrequency fields related to mobile phones and base stations
Keywords: CDMA; code division multiple access; CEMFEC; acronym of the European project “Combined effects of electromagnetic fields with environmental carcinogens”; CNS; central nervous system; DAMPS; digital advanced mobile phone systems; DCS; digital personal
Chemoprevention of hepatocellular carcinoma: Use of tamoxifen in an animal model of hepatocarcinogenesis
Keywords: ENU; ethyl nitrosurea; H&E; hematoxylin and eosin; HCC; hepatocellular carcinoma;
Neurogenic tumors in rats induced by ethylnitrosourea
Keywords: Ethylnitrosourea; ENU; Brain tumors; Nerve tumors; Rats;
Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model
Keywords: APC; antigen-presenting cell; CTL; cytotoxic T lymphocyte; DC; dendritic cell; ENU; N-ethyl-N-nitrosourea; IFN; interferon; IL; interleukin; LT-β; lymphotoxin-β; MCMV; mouse cytomegalovirus; MyD88; myeloid differentiation antigen 88; TIR; Toll/IL-1 rece
Molecular characterization of ENU mouse mutagenesis and archives
Keywords: Genomics; Mouse genome; Mutation; Mutagenesis; ENU; Reverse genetics;
Mouse mutants as models for congenital retinal disorders
Keywords: animal model; retina; mouse; gene mutation; retinal degeneration; BBS; Bardet-Biedl syndrome; ENU; N-ethyl-N-nitrosourea; ERG; electroretinogram; LCA; Leber's congenital amaurosis; RP; retinitis pigmentosa; RPE; retinal pigment epithelium; STGD; Stargardt
Frequent retention of heterozygosity for point mutations in p53 and Ikaros in N-ethyl-N-nitrosourea-induced mouse thymic lymphomas
Keywords: ENU; Heterozygous mutation; p53; Ikaros;
Patulin-producing molds in corn silage and high moisture corn and effects of patulin on fermentation by ruminal microbes in continuous culture
Keywords: APDA; acid potato dextrose agar; cfu/g; colony forming units per gram; CYA; Czapeck yeast autolysate; PDA; potato dextrose agar; YES; yeast extract sucrose; DM; dry matter; OM; organic matter; CP; crude protein; NDF; neutral detergent fiber; ADF; acid det
New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant
Keywords: MMS; methyl methanesulfonate; EMS; ethyl methanesulfonate; MNU; methylnitrosourea; ENU; ethylnitrosourea; CNU; chloroethylnitrosourea; IR; ionizing radiation; MMC; mitomycin C; HR; homologous recombination; HRR; homologous recombinational repair; ROS; rea
Nitrogen Metabolism in the Rumen*
Keywords: rumen; nitrogen; metabolism; microbial; CHO; carbohydrate; EMPS; efficiency of microbial protein synthesis; ENU; efficiency of N utilization; FOM; fermented OM; TDN; total digestible nutrients;
Age-dependent sensitivity of Big Blue transgenic mice to the mutagenicity of N-ethyl-N-nitrosourea (ENU) in liver
Keywords: ENU; N-ethyl-N-nitrosourea; PNDs; postnatal days; MF; mutant frequency; DMSO; dimethylsulfoxide; Ethylnitrosourea; Age; Neonate; Mutagenicity; Transgenic mice; Sensitivity;
Utilization of macro-algae for enhanced CO2 fixation and biofuels production: Development of a computing software for an LCA study
Keywords: LCA; life cycle assessment; LCI; life cycle inventory; scCO2; supercritical carbon dioxide; MEA; monoethanolamine, HOCH2CH2NH2; SETAC; Society of Environmental Toxicology and Chemistry; SCFE; supercritical fluid extraction; Enet; net energy; Eric; energy