A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase Fold
Keywords: EPK, eukaryotic protein kinase; ELK, eukaryote-like kinase; PDK1, phosphoinositide-dependent kinase 1; PDB, Protein Data Bank; CDK2, cyclin-dependent kinase 2; PKA, protein kinase A; Bicine, N,N-bis(2-hydroxyethyl)glycine; ASA, solvent-accessible surface