دانلود مقالات ISI درباره تعادل تعادل ثابت + ترجمه فارسی

Determine equilibrium dissociation constant of drug-membrane receptor affinity using the cell membrane chromatography relative standard method

Keywords: تعادل تعادل ثابت; Cell membrane chromatography; Equilibrium dissociation constant; Drug-membrane receptor affinity; Relative standard method;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

پراکسیس مهارکننده های پپتیکی توسط پروتئین هدف بوسیله انتقال پروتئین پپتید ایجاد می شود

Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition

Keywords: تعادل تعادل ثابت; Enzyme catalysis; Cyclic peptide; Protease inhibitor; Substrate; Crystal structure; uPA; urokinase-type plasminogen activator serine protease domain of uPA (residues 16-244); uPA16-244; equilibrium dissociation constant; KD; equilibrium inhibition con

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

تعیین مقدار تستوسترون با تداخل سنجی بیولوژیک

Quantitative determination of testosterone levels with biolayer interferometry

Keywords: تعادل تعادل ثابت; Biolayer interferometry; Comamonas testosteroni; DNA/protein interaction; Quantitative determination of testosterone; 3α-HSD/CR; 3α-hydroxysteroid dehydrogenase/carbonyl reductase; BIA; biomolecular interaction analysis; BLI; Biolayer interferometry; bp

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

مقدمه ای بر مکانیسم پروتئازی سریین بر اساس مشاهدات ساختاری از تبدیل یک مهار کننده پروتئاز پپتیدیل سرین به یک سوبسترا

Insights into the serine protease mechanism based on structural observations of the conversion of a peptidyl serine protease inhibitor to a substrate

Keywords: تعادل تعادل ثابت; uPA; urokinase-type plasminogen activator; uPA16-244; serine protease domain of uPA (residues 16-244); KD; equilibrium dissociation constant; Ki; equilibrium inhibition constant; PAB; p-aminobenzamidine; Serine proteases; uPA; Enzyme catalysis; Cyclic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

مقایسه پلت فرم های بیوسنسور در ارزیابی سینتیک اتصال آنتی بادی آنتی بادی بالینی

Comparison of biosensor platforms in the evaluation of high affinity antibody-antigen binding kinetics

Keywords: تعادل تعادل ثابت; Biacore; ProteOn; Octet; MX96; Antibody-antigen interactions; Optical biosensor; mAb; monoclonal antibody; SPR; surface plasmon resonance; BLI; Bio-Layer Interferometry; CFM; continuous flow microfluidics; PCSK9; proprotein convertase substilisin kexin ty

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2016 سفارش ترجمه

اشعه گامای یونیزه با دوز کم تاثیر بر همکاری پروتئین های اختصاصی آندروژن دارد

The low dose gamma ionising radiation impact upon cooperativity of androgen-specific proteins

Keywords: تعادل تعادل ثابت; Androgens; Androgenic receptor; Hexokinase; Ionising radiation; Testosterone-binding globulin; A; androgen(s); aa; amino acids; ABP; androgen-binding protein of rat i.e. rTeBG; AC; adenylate cyclase; AR; androgen receptor; ARC; androgen receptor complex;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

واکسیناسیون موش ها را از اختلال ناشی از متامفتامین در پاسخگویی به رفتار غذا محافظت می کند

Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food

Keywords: تعادل تعادل ثابت; AMP; (+)-amphetamine; Cys; L-cysteine; FI; fixed-interval schedule of behavioral reinforcement; FR; fixed-ratio schedule of behavioral reinforcement; [3H]-METH; (+)-[2′,6′-3H(n)]-methamphetamine; HSMO9; the METH-like hapten (S)-N-(2-(mercaptoethyl)-6-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Receptor partial agonism and method to express receptor partial activation with respect to novel Full Logistic Model of mixture toxicology

Keywords: تعادل تعادل ثابت; Receptor theory; Partial agonist; Mixture toxicology; Equilibrium dissociation constant; Efficacy; Drug potency;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Novel compounds TAD-1822-7-F2 and F5 inhibited HeLa cells growth through the JAK/Stat signaling pathway

Keywords: تعادل تعادل ثابت; RPMI; Roswell Park Memorial Institute; FBS; fetal bovine serum; IC50; 50%-growth inhibitory concentrations; RTCA; Real Time Cell Analysis; SPR; surface plasmon resonance; QCM; quartz crystal microbalance; KD; equilibrium dissociation constant; HeLa; TAD-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Construction of humanized anti-HER2 single-chain variable fragments (husFvs) and achievement of potent tumor suppression with the reconstituted husFv-Fdt-tBid immunoapoptotin

Keywords: تعادل تعادل ثابت; HER2; Immunogenicity; Humanized scFv; Immunoapoptotin; Targeted cancer therapy; Apoptosis; HER2; human epidermal growth factor receptor 2; scFv; single-chain variable fragment; husFv; humanized e23sFv; VL; light chain variable region; VH; heavy chain vari

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Overview of the detection methods for equilibrium dissociation constant KD of drug-receptor interaction

Keywords: تعادل تعادل ثابت; Equilibrium dissociation constant; Drug-receptor interaction; RBA; SPR; FRET; Affinity chromatography;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Interaction of cholera toxin B subunit with T and B lymphocytes

Keywords: تعادل تعادل ثابت; CT-B; cholera toxin B subunit; IFN-α; interferon-α; Kd; equilibrium dissociation constant; Ki; equilibrium inhibition constant; SEM; standard error of the mean; TM- α1; thymosin-α1; Protein; Peptide; Receptor; Cholera toxin B subunit; Lymphocyte;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Thermodynamics of interactions between mammalian cytochromes P450 and b5

Keywords: تعادل تعادل ثابت; Cytochrome P450; Cytochrome b5; SPR; Optical biosensor; Thermodynamics; Protein-protein interactions; CYP; ≿ytochrome P450; CYB5; ≿ytochrome b5; CYB5A and CYB5B; microsomal and mitochondrial isoforms of b5; SPR; surface plasmon resonance; RU; resonanc

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and binding characteristics of [3H]neuromedin N, a NTS2 receptor ligand

Keywords: تعادل تعادل ثابت; BH; Bolton-Hunter; Bmax; maximal number of the binding sites; BSA; bovine serum albumin; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; EC50; half maximal effective concentration; Emax; maximal stimulation (Efficacy); GDP; guanosine 5′-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength

Keywords: تعادل تعادل ثابت; CSP; Chemical-Shift Perturbations; Cbc1; cytochrome bc1; Cc; cytochrome c; CcO; cytochrome c oxidase; Cc1; cytochrome c1; (III); complex III; (IV); complex IV; DLS; dynamic light scattering; ET; electron transfer; KD; equilibrium dissociation constant; HS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome

Keywords: تعادل تعادل ثابت; AP; alternative pathway; aHUS; atypical hemolytic uremic syndrome; CP; classical pathway; CR1; complement receptor 1; DAF; decay accelerating factor; DDD; dense deposit disease; EM; electron microscopy; FB; factor B; FD; factor D; FH; factor H; FI; factor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Leukemia inhibitory factor (LIF)

Keywords: تعادل تعادل ثابت; Leukemia inhibitory factor; JAK/STAT/SOCS; LIF receptor; Embryonic stem cells; Pregnancy; Nerve and muscle; LIF; leukemia inhibitory factor; CNTF; ciliary neurotrophic growth factor; CT1; cardiotrophin 1; CLC; carditrophin-like cytokine; JAK; Janus kinase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

pH dependence of cyanide and imidazole binding to the heme domains of Sinorhizobium meliloti and Bradyrhizobium japonicum FixL

Keywords: تعادل تعادل ثابت; FixL; heme sensor protein found in nitrogen-fixing bacteria; FixLH; truncated version of FixL containing the soluble heme domain; BjFixL; FixL from Bradyrhizobium japonicum; BjFixLH; FixLH from Bradyrhizobium japonicum; SmFixL; FixL from Sinorhizobium mel

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

A surface plasmon resonance study of the intermolecular interaction between Escherichia coli topoisomerase I and pBAD/Thio supercoiled plasmid DNA

Keywords: تعادل تعادل ثابت; Surface plasmon resonance; Bacterial topoisomerase I; Supercoiled plasmid DNA; Capture covalent method; Equilibrium dissociation constant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Isolated noncatalytic and catalytic subunits of F1-ATPase exhibit similar, albeit not identical, energetic strategies for recognizing adenosine nucleotides

Keywords: تعادل تعادل ثابت; Mg(II); free magnesium ion; ATP; adenosine 5′-triphosphate; ADP; adenosine 5′-diphosphate; EDTA; ethylenediaminetetraacetic acid; Tris; 2-amino-2-(hydroxymethyl)propane-1,3-diol; MgCl2; magnesium chloride; ATPase; adenosine 5′-triphosphatase; TF1; F

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor

Keywords: تعادل تعادل ثابت; Boc; butoxycarbonyl; Bmax; receptor density; DMEM; Dulbecco's Modified Eagle's Medium; DMF; N,N-dimethylformamide; FBS; fetal bovine serum; GPCR; G protein-coupled receptor; HBTU; 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

Keywords: تعادل تعادل ثابت; HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; DHP; 6-hydroxymethyl-7,8-dihydropterin; DHPS; dihydropteroate synthase; SPR; surface plasmon resonance; KD; equilibrium dissociation constant; IC50; half maximal inhibitory concentration; AMPCPP;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

Keywords: تعادل تعادل ثابت; SARS-CoV; Severe Acute Respiratory Syndrome coronavirus; 3CLpro; 3 Chymotrypsin-like cysteine protease; MD; molecular dynamics; VS; virtual screening; CSM; computational solvent mapping; ROC; receiver operating characteristic; RMSD; root mean square devia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α

Keywords: تعادل تعادل ثابت; PPAR; peroxisome proliferator-activated receptor; LBD; ligand-binding domain; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescent resonance energy transfer; TG; triglyceride; HTG; hypertriglyceridemia; RXR; retinoid X receptor; EO; essentia

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes

Keywords: تعادل تعادل ثابت; LXR; liver X receptor; LBD; ligand-binding domain; RXR; retinoid X receptor; KD; equilibrium dissociation constant; EC50; the half maximal effective concentration; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescent resonance energy transfe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Lymphocyte glucocorticoid receptor expression level and hormone-binding properties differ between war trauma-exposed men with and without PTSD

Keywords: تعادل تعادل ثابت; PTSD; posttraumatic stress disorder; GR; glucocorticoid receptor; PBMCs; peripheral blood mononuclear cells; Bmax; number of glucocorticoid binding sites; KD; equilibrium dissociation constant; HPA axis; hypothalamic-pituitary-adrenocortical axis; CAPS-DX

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Supporting immunoassay design with biophysical tools

Keywords: تعادل تعادل ثابت; NGAL; Immunoassay; Microparticles; Equilibrium dissociation constant; Binding kinetics; Antibody; Chemiluminescence; Fluorescence

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Revealing multi-binding sites for taspine to VEGFR-2 by cell membrane chromatography zonal elution

Keywords: تعادل تعادل ثابت; Vascular endothelial growth factor receptor-2; Cell membrane chromatography; Equilibrium dissociation constant; Binding site; Sorafenib; Taspine

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Rapid affinity measurement of protein–protein interactions in a microfluidic platform

Keywords: تعادل تعادل ثابت; Binding affinity; Equilibrium binding constant; Equilibrium dissociation constant; GYROS; Gyrolab; KinExA; Antigen–antibody binding; Rapid affinity ranking

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Regular ArticleThe inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives

Keywords: تعادل تعادل ثابت; ECM; extracellular matrix; EDC; N-ethyl-N-(dimethylaminopropyl)-carbodiimide; FCS; fetal calf serum; HRP; horseradish peroxidase; KD; equilibrium dissociation constant; koff; dissociation rate constant (off-rate); kon; association rate constant (on-rate);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanism of transcription initiation by the yeast mitochondrial RNA polymerase

Keywords: تعادل تعادل ثابت; mtRNAP; mitochondrial RNAP; Ymt; yeast mitochondrial; Mtf1; mitochondrial transcription factor 1; nt; nucleotides; aa; amino acids; SAM; S-adenosyl-l-methionine; Kd; equilibrium dissociation constant; FRET; fluorescence resonance energy transfer; 2-AP; 2-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation

Keywords: تعادل تعادل ثابت; Pol β; DNA polymerase β; BER; base excision repair; AP; apurinic/apyrimidinic; APE1; AP endonuclease 1; dRP; deoxyribose phosphate; NEIL; Nei-like; WT; wild-type; Tet; tetracycline; MEF; mouse embryonic fibroblast; Hyg; hygromycin; SDS; sodium dodecyl s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The ribosome modulates the structural dynamics of the conserved GTPase HflX and triggers tight nucleotide binding

Keywords: تعادل تعادل ثابت; HflX; Nucleotide binding; Ribosome; Limited trypsinolysis; GTPase-activated state; Stopped-flow; P-loop; phosphate-binding loop; GEF; guanine nucleotide exchange factor; GAP; GTPase activating protein; GDI; guanine nucleotide dissociation inhibitor; EF; e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT

Keywords: تعادل تعادل ثابت; ADAR; adenosine deaminase that acts on RNA; ADAT; adenosine deaminase that acts on tRNA; AU; analytical ultracentrifugation; DIP1; Disconnected Interacting Protein 1; DIP1-c; longest DIP1 isoform; dsRBD; double-stranded RNA-binding domain; dsRNA; double-s

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

A comprehensive study on the putative δ-opioid receptor (sub)types using the highly selective δ-antagonist, Tyr-Tic-(2S,3R)-β-MePhe-Phe-OH

Keywords: تعادل تعادل ثابت; Bmax; receptor density; BNTX; 7-benzylidenenaltrexone; DADLE; [d-Ala2,d-Leu5]enkephalin; deltorphin II; Tyr-d-Ala-Phe-Glu-Val-Val-Gly-NH2; DOR-1; δ-opioid receptor; DOR-KO; δ-opioid receptor knock-out; DPDPE; Tyr-c[d-Pen-Gly-Phe-d-Pen]-OH; DSLET; Tyr-d-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

MALDI Immunoscreening (MiSCREEN): A method for selection of anti-peptide monoclonal antibodies for use in immunoproteomics

Keywords: تعادل تعادل ثابت; MiSCREEN; MALDI immunoscreening; mAbs; monoclonal antibodies; MALDI-TOF; matrix-assisted laser desorption/ionization time-of-flight; MS; mass spectrometry; SPR; surface plasmon resonance; SISCAPA; stable isotope standards and capture by anti-peptide antib

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Comparison of the results obtained by ELISA and surface plasmon resonance for the determination of antibody affinity

Keywords: تعادل تعادل ثابت; Fibronectin–antibody interaction; Surface plasmon resonance; Enzyme linked immunosorbent assay; Dissociation rate constant; Association rate constant; Equilibrium dissociation constant

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

The mechanism of action of tapasin in the peptide exchange on MHC class I molecules determined from kinetics simulation studies

Keywords: تعادل تعادل ثابت; ADT; average dwelling time; β2m; beta-2 microglobulin; CTL; cytotoxic T lymphocyte; ER; endoplasmic reticulum; GFP; Green Fluorescent Protein; k; reaction rate constant; KD; equilibrium dissociation constant; MHC; major histocompatibility complex; ODE; o

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Re-examining the proposed lectin properties of IL-2

Keywords: تعادل تعادل ثابت; 2-ME; 2-mercaptoethanol; BSA; bovine serum albumin; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; HSQC; heteronuclear single quantum correlation; IL-2; interleukin-2; KD; equilibrium dissociation c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Increased glutamate receptor gene expression in the cerebral cortex of insulin induced hypoglycemic and streptozotocin-induced diabetic rats

Keywords: تعادل تعادل ثابت; hypoglycemia; glutamate excitotoxicity; cerebral cortex; NMDA2B; mGluR5; ANOVA; analysis of variance; Bmax; maximal binding; CT; threshold cycle; IIH; insulin-induced hypoglycemia; Kd; equilibrium dissociation constant; mGluR; metabotropic glutamate recep

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The conserved residue Phe273(282) of PPARα(γ), beyond the ligand-binding site, functions in binding affinity through solvation effect

Keywords: تعادل تعادل ثابت; Peroxisome proliferator-activated receptor (PPAR); Mutation; Ligand-binding affinity; Solvation effect; Molecular dynamics; Surface plamon resonance (SPR); Transcriptional activation; PPAR; peroxisome proliferator-activated receptor; KD; equilibrium disso

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Measurement of the functional affinity constant of a monoclonal antibody for cell surface receptors using kinetic exclusion fluorescence immunoassay

Keywords: تعادل تعادل ثابت; KinExA; kinetic exclusion assay; ELISA; enzyme-linked immunosorbent assay; hIGFR; human insulin-like growth factor I receptor; NHS-PMMA beads; N-hydroxysuccinimide-polymethyl methacrylate beads; NSB; non-specific binding; Kd; equilibrium dissociation co

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه