Keywords: ERK، کیناز تنظیم شده خارج سلولی; Andro, andrographolide; ERK, extracellular regulated kinase; HCC, Hepatocellular carcinoma; HPLC, high pressure liquid chromatography; JNK, c-Jun N-terminal kinase; KEGG, Kyoto Encyclopedia Genes $amp Genomes; MPAKs, mitogen-activated protein kinases; miR
مقالات ISI ERK، کیناز تنظیم شده خارج سلولی (ترجمه نشده)
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Keywords: ERK، کیناز تنظیم شده خارج سلولی; AMP, antimicrobial peptide; ERK, extracellular regulated kinase; FU, functional unit; Hc, hemocyanin; Hc-d PO, hemocyanin-derived phenoloxidase; HSC, horseshoe crab; IgSF, immunoglobulin superfamily; LPS, lipopolysaccharide; PAMP, pathogen associated mole
Concomitant partial exon skipping by a unique missense mutation of RPS6KA3 causes Coffin–Lowry syndrome
Keywords: ERK، کیناز تنظیم شده خارج سلولی; CLS, Coffin–Lowry syndrome; RPS6KA3, Ribosomal Protein S6 Kinase Polypeptide 3; RSK2, ribosomal S6 kinase 2; RT-PCR, reverse transcription polymerase chain reaction; cDNA, complementary DNA; ATP, adenosine triphosphate; ERK, extracellular regulated kinase
Neuroprotective effects of pterostilbene against oxidative stress injury: Involvement of nuclear factor erythroid 2-related factor 2 pathway
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ANOVA, analysis of variance; ARE, antioxidant response element; CCK8, Cell Counting Kit-8; CO, carbon monoxide; DAPI, 4′,6-diamino-2-phenylindole; DMEM, Dulbecco's modified Eagle's medium; DMSO, dimethylsulfoxide; ERK, extracellular regulated kinase; FBS,
The neuron-astrocyte-microglia triad involvement in neuroinflammaging mechanisms in the CA3 hippocampus of memory-impaired aged rats
Keywords: ERK، کیناز تنظیم شده خارج سلولی; aCSF, artificial cerebrospinal fluid; AD, Alzheimer's disease; AL, acquisition latency; CA, Cornu Ammonis; CytC, cytochrome C; DAB, 3,3′-diaminobenzidine; ERK, extracellular regulated kinase; GABA, gamma-aminobutyric acid; GFAP, glial fibrillary acidic pr
α-Tocopherol suppresses antiangiogenic effect of δ-tocotrienol in human umbilical vein endothelial cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; DLD-1, human colorectal adenocarcinoma; ERK, extracellular regulated kinase; HPLC, high-performance liquid chromatography; HUVEC, human umbilical vein endothelial cell; PTEN, phosphatase and tensin homolog deleted from chromosome 10; RT-PCR, reverse trans
Enriched inorganic compounds in diesel exhaust particles induce mitogen-activated protein kinase activation, cytoskeleton instability, and cytotoxicity in human bronchial epithelial cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; DEP, diesel exhaust particles; DEP/HEX, diesel exhaust particles treated with hexane; MAPK, mitogen activated protein kinases; PAHs, polycyclic aromatic hydrocarbons; LDH, lactate dehydrogenase; ERK, extracellular regulated kinase; pERK, phosphorylated ex
MMP2 and MMP9 participate in S1P-induced invasion of follicular ML-1 thyroid cancer cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; HIF-1α, hypoxia inducible transcription factor 1α; LOX, lysyl oxidase; MMP, matrix metalloproteinase; PKC, protein kinase C; PI3K, phosphoinositide 3-kinase; S1P, sphingosine-1-phosphate; S1P1,3, S1P receptors 1 and 3;
Antiproliferative potential of a novel parthenin analog P16 as evident by apoptosis accompanied by down-regulation of PI3K/AKT and ERK pathways in human acute lymphoblastic leukemia MOLT-4 cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; AKT/PKB, protein kinase B; ERK, extracellular regulated kinase; IC50, half maximal inhibitory concentration; ICAD, inhibitor of caspase activated DNase; KRAS, Kirsten rat sarcoma viral oncogene homolog; MTT, 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetra
Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: Importance of the TACE/TGF-α/EGFR-pathway
Keywords: ERK، کیناز تنظیم شده خارج سلولی; 3-ABA, 3-aminobenzanthrone; 3-AF, 3-aminofluoranthene; 1-AP, 1-aminopyrene; COPD, chronic obstructive pulmonary disease; DEP, diesel exhaust particles; EGFR, epidermal growth factor receptor; ERK, extracellular regulated kinase; IL-8, interleukin-8; JNK,
Cannabinoid agonists increase the interaction between β-Arrestin 2 and ERK1/2 and upregulate β-Arrestin 2 and 5-HT2A receptors
Keywords: ERK، کیناز تنظیم شده خارج سلولی; 5-HT, 5-hydroxytryptamine; 5-HT2A, serotonin 2A; Δ9-THC, Δ9-tetrahydrocannabinol; ERK, extracellular regulated kinase; PFCx, prefrontal cortex; GPCR, G-protein coupled receptor; MAP, mitogen activated protein kinase; pERK, phosphorylated extracellular reg
Specific phosphorylation of αA-crystallin is required for the αA-crystallin-induced protection of astrocytes against staurosporine and C2-ceramide toxicity
Keywords: ERK، کیناز تنظیم شده خارج سلولی; AP, activating peptide; Cer, C2-ceramide; CRYAA, αA-crystallin; ERK, extracellular regulated kinase; LDH, lactate dehydrogenase; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinase; MH, myc-his; PAR-2, protease-activated receptor-2; STS,
Profound conformational changes of PED/PEA-15 in ERK2 complex revealed by NMR backbone dynamics
Keywords: ERK، کیناز تنظیم شده خارج سلولی; PED/PEA-15, phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes, 15 kDa; ERK, extracellular regulated kinase; DED, death effector domain; CSP, chemical shift perturbation; TROSY, transverse relaxation optimized spectroscopyNMR dynami
Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Resveratrol; cyclin D1; MAP kinases; Akt and Pak1 kinasePCNA, proliferation cell nuclear antigen; MAP kinase, Mitogen activated protein kinase; ERK, extracellular regulated kinase; GSK3β, glycogen synthase kinase 3β; Pak1, p21 activated kinase
Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Bcl-2, B-cell lymphoma 2; Cyt c, cytochrome c; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DMSO, dimethyl sulfoxide; DPI, dipheylene iodide; ERK, extracellular regulated kinase; JNK, c-Jun-N-terminal protein kinase; MAPK, mitogen-activated protein kinas
Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression
Keywords: ERK، کیناز تنظیم شده خارج سلولی; 7-CHO, 7-ketocholesterol; 25OHC, 25hydroxycholesterol; ERK, extracellular regulated kinase; JNK, Jun N-terminal kinase; IL-1β, interleukin1β; IL-6, interleukin 6; IL-8, interlerleukins-8 liver X receptor (LXR); MAPK, mitogen-activated proteinkinase; NF-κB
Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Mevalonate pathway; Small GTPases; Anticancer drugs; DNA damage response (DDR); Sarcoma cellsATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; Chk, checkpoint kinase; DDR, DNA damage response; ERK, extracellular regulated kinase; H2AX, histon
Differential expression of toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; Jnk, c-Jun NH2-terminal kinase; LBP, lipopolysaccharide binding protein; LPS, lipopolysaccharide; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor κB; PBMC, peripheral blood mononuclear cells; PCR, polymer
Early c-Jun N-terminal kinase-dependent phosphorylation of activating transcription factor-2 is associated with degeneration of retinal ganglion cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; activating transcription factor 2; c-Jun N-terminal kinase; programmed cell death; retinaATF-2, activating transcription factor 2; bZIP, basic domain leucine zipper; ERK, extracellular regulated kinase; GCL, ganglion cell layer; IPL, inner plexiform layer
Caveolin 1 is a marker of poor differentiation in Rhabdomyosarcoma
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Rhabdomyosarcoma; Skeletal muscle; Caveolin 1; Caveolin 3; ERK pathwayBSA, bovine serum albumin; DMEM, Dulbecco’s modified Eagle’s medium; DMSO, dimethylsulfoxide; ERK, extracellular regulated kinase; MAPK, mitogen-activated protein kinases; MEK, MAP/ERK
Snail transcription factors in keratinocytes: Enough to make your skin crawl
Keywords: ERK، کیناز تنظیم شده خارج سلولی; CK, calmodulin kinase; COX2, cyclooxygenase-2; ECM, extracellular matrix; EGFR, epidermal growth factor receptor; EMT, epithelial–mesenchymal transition; ERK, extracellular regulated kinase; GSK, glycogen synthase kinase; HNSCC, head and neck squamous cel
Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration
Keywords: ERK، کیناز تنظیم شده خارج سلولی; DMEM, Dulbecco’s Modified Eagle’s Medium; ER, estrogen receptor; ERK, extracellular regulated kinase; FBS, fetal bovine serum; FITC, fluoresceine iso thio cyanate; IGF-2, insulin-like growth factor-2; KO, knock out; PTP1B, protein tyrosine phosphatase-1B;
Mutation of tyrosine residue 857 in the PDGF β-receptor affects cell proliferation but not migration
Keywords: ERK، کیناز تنظیم شده خارج سلولی; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; Erk, extracellular regulated kinase; PAE, porcine aortic endothelial cell; PI3K, phosphatidylinositol 3-kinase; FBS, fetal bovine serum; SH2, Src homology 2; SHP-2, SH2-domain containing phosphat
Erk 5 is necessary for sustained PDGF-induced Akt phosphorylation and inhibition of apoptosis
Keywords: ERK، کیناز تنظیم شده خارج سلولی; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; Erk, extracellular regulated kinase; MAPK, mitogen activated protein kinase; PAE, porcine aortic endothelial cell; PI3-kinase, phosphatidylinositol 3-kinase; PKC, protein kinase C; FBS, fetal bov
The flavonoids luteolin and quercetagetin inhibit lipoteichoic acid actions on H9c2 cardiomyocytes
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; JNK, c-Jun N-terminal kinases; LTA, lipoteichoic acid; IL1β, Interleukin-1βFlavonoids; Lipoteichoic acid; Endocarditis; Mitogen-activated protein kinases; IL-1β; Rat heart embryonic cells
Echinacea purpurea extracts modulate murine dendritic cell fate and function
Keywords: ERK، کیناز تنظیم شده خارج سلولی; APC, antigen presenting cell; BMDC, bone marrow-derived dendritic cell; CFSE, carboxyfluorescein succinimidyl ester; COX, cyclooxygenase; DC, dendritic cell; ERK, extracellular regulated kinase; FITC, fluorescein isothiocyanate; JNK, c-Jun NH2 terminal ki
Rhizoctonia bataticola lectin (RBL) induces mitogenesis and cytokine production in human PBMC via p38 MAPK and STAT-5 signaling pathways
Keywords: ERK، کیناز تنظیم شده خارج سلولی; RBL, Rhizoctonia bataticola lectin; PBMC, Peripheral blood mononuclear cells; MAPK, Mitogen Activated Protein Kinase; ERK, Extracellular regulated kinase; JAK, Janus Kinase; STAT, Signal Transducers and Activators of Transcription; IL-2Rα, Interleukin-2 r
Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics
Keywords: ERK، کیناز تنظیم شده خارج سلولی; 5BrdU, 5-bromodeoxyuridine; AREG, amphiregulin; CDβgeo, COMMA-D β-geo cell line; EGF, epidermal growth factor; Erk, extracellular regulated kinase; MAPK, mitogen activated protein kinase; TGF-α, transforming growth factor-αAmphiregulin; Mammary; Mammosphe
Regulation of peripheral myelination by Src-like kinases
Keywords: ERK، کیناز تنظیم شده خارج سلولی; BSA, Bovine serum albumin; CNP, 2′-3′-cyclic nucleotide-2′-phosphodiesterase; CNS, central nervous system; DAPI, 4′,6-diamidino-2-phenylindole; DRGN, dorsal root ganglion neuron; ECM, extracellular matrix; ERK, extracellular regulated kinase; FAK, focal a
A current view of brain renin–angiotensin system: Is the (pro)renin receptor the missing link?
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Agt, angiotensinogen; Ang, angiotensin; AT1R, Ang II type 1 receptor; ACE, angiotensin converting enzyme; AVP, arginine-vasopressin; BP, blood pressure; ERK, extracellular regulated kinase; IML, intermediolateral cell column of the spinal cord; ICV, intra
Fibronectin induces matrix metalloproteinase-9 (MMP-9) in human laryngeal carcinoma cells by involving multiple signaling pathways
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Fibronectin; MMP-9; Laryngeal cancer; Signaling; InvasionAP-1, Activator protein-1; ECM, extracellular matrix; EMSA, Electrophoretic mobility shift assay; ERK, Extracellular regulated kinase; FAK, Focal adhesion kinase; FBS, fetal bovine serum; FITC, fluo
Regulatory mechanisms in lymphatic vessel contraction under normal and inflammatory conditions
Keywords: ERK، کیناز تنظیم شده خارج سلولی; SM, smooth muscle; MHC, myosin heavy chain; MLC, myosin light chain; MLCK, myosin light chain kinase; MLCP, myosin light chain phosphatase; TM, tropomyosin; CaD, caldesmon; ERK, extracellular regulated kinase; Tn, troponin; TXA2, thromboxane A2; PAR2, pro
Wound healing in the 21st century
Keywords: ERK، کیناز تنظیم شده خارج سلولی; cellular; molecular; novel findings; signal transduction; pH value; skin woundAGE, advanced glycation end product; Cyr61, cysteine-rich angiogenic inducer-61; ECM, extracellular matrix; EGF, epidermal growth factor; ERK, extracellular regulated kinase; FG
Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease
Keywords: ERK، کیناز تنظیم شده خارج سلولی; BMDM, bone marrow-derived macrophages; C2-ceramide, N-acetylsphingosine; C8-ceramide, N-octanoylsphingosine; C1P, ceramide-1-phosphate; DAG, diacylglycerol; ERK, extracellular regulated kinase; GSH, glutathione; LPP, lipid phosphate phosphatase; MAPK, mit
Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras
Keywords: ERK، کیناز تنظیم شده خارج سلولی; BAP31, B-lymphocyte receptor-associated protein 31; CMT2A, Charcot-Marie-Tooth type 2A neuropathy; Drp1, dynamin-related protein 1; ER, endoplasmic reticulum; ERK, extracellular regulated kinase; GAP, GTPase-activating protein; GEF, guanine exchange facto
Implication of protein tyrosine phosphatase 1B in MCF-7 cell proliferation and resistance to 4-OH tamoxifen
Keywords: ERK، کیناز تنظیم شده خارج سلولی; 4-OHT, 4-OH tamoxifen; DMEM, Dulbecco’s modified Eagle’s medium; ER, estrogen receptor; ERK, extracellular regulated kinase; FBS, fetal bovine serum; FITC, fluorescein isothiocyanate; KO, knockout; PTP1B, protein tyrosine phosphatase 1B; PTPase, protein t
Cytotoxicity of methoctramine and methoctramine-related polyamines
Keywords: ERK، کیناز تنظیم شده خارج سلولی; DAPI, 4′,6-diamidino-2-phenylindole; DENSPM, N1,N11-diethylnorspermine; ERK, extracellular regulated kinase; NAC, N-acetylcysteine; NMDA, N-methyl-d-aspartate; ODC, ornithine decarboxylase; SSAT, spermidine/spermine N1-acetyltransferaseMethoctramine; Poly
A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats
Keywords: ERK، کیناز تنظیم شده خارج سلولی; AKT/PKB, protein kinase B; ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; DEN, N-nitrosodiethylamine; ERK, extracellular regulated kinase; FBS, fetal bovine serum; GPx, glutathione peroxidase; GR, glutathione reductase;
Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ANOVA, analysis of variance; BSA, bovine serum albumin; CKD712, (S)-1(-α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; DMEM, Dulbecco's modified Eagle's medium; ECL, enhanced chemoluminescence; ERK, extracellular regulated kinase; FBS, fet
Bile Salts Control the Antimicrobial Peptide Cathelicidin Through Nuclear Receptors in the Human Biliary Epithelium
Keywords: ERK، کیناز تنظیم شده خارج سلولی; CDCA, chenodeoxycholic acid; ERK, extracellular regulated kinase; FXR, farnesoid X receptor; hBD-2, human β 2 defensins; PBC, primary biliary cirrhosis; PCR, polymerase chain reaction; VDR, vitamin D nuclear receptor; VDRE, VDR response element
Insulin induced alteration in post-translational modifications of histone H3 under a hyperglycemic condition in L6 skeletal muscle myoblasts
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Cat, Catalase; CM-DCF-DA, 5, 6-chloromethyl-2′,7′-dichlorofluorescein diacetate; DPI, diphenylene iodonium; ERK, extracellular regulated kinase; HAT, histone acetyltransferase; HDAC, histone deacetylase; MAPK, mitogen activated protein kinase; NOX, NADPH
Molecular modeling and crystal structure of ERK2–hypothemycin complexes
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; RAL, resorcylic acid lactone; MM, molecular mechanics; MD, molecular dynamicsHypothemycin; ERK2; Resorcylic acid lactones; Molecular modeling; Crystal structure
Eupatilin inhibits H2O2-induced apoptotic cell death through inhibition of mitogen-activated protein kinases and nuclear factor-κB
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; MAPK, mitogen-activated protein kinases; NAC, N-acetyl-cysteine; NF-κB, nuclear factor-κB; PMA, phorbol 12-myristate 13-acetate; ROS, reactive oxygen speciesEupatilin; H2O2; Apoptosis; Nuclear factor-κB; Mitogen-activa
Effects of PPAR agonists on proliferation and differentiation in human urothelium
Keywords: ERK، کیناز تنظیم شده خارج سلولی; Peroxisome proliferator-activated receptor; Differentiation; Proliferation; Epidermal growth factor; Bladder; Urothelium; Uroplakin; ClaudinAUM, asymmetric unit membrane; CK, cytokeratin; EGF, epidermal growth factor; ERK, extracellular regulated kinase;
Oxidative stress and vascular disease in diabetes: Is the dichotomization of insulin signaling still valid?
Keywords: ERK، کیناز تنظیم شده خارج سلولی; EPC, endothelial progenitor cells; ERK, extracellular regulated kinase; MAPK, mitogen-activated protein kinase; MetSyn, metabolic syndrome; MKKK, mitogen-activated protein kinase kinase kinase; PI3K, phosphoinositide 3-kinase; PKB, protein kinase B; PDK1,
Effects of mutant human Ki-rasG12C gene dosage on murine lung tumorigenesis and signaling to its downstream effectors
Keywords: ERK، کیناز تنظیم شده خارج سلولی; AC, adenocarcinomas; AD, adenomas; CCSP, Clara cell secretory protein; DOX, doxycycline; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; erk, extracellular regulated kinase; JNK, Jun kinase; MAPK, mitogen activated protein kinase; MEK, mitogen activated
Heat stress-induced heat shock protein 70 expression is dependent on ERK activation in zebrafish (Danio rerio) cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ERK, extracellular regulated kinase; Hsf, heat shock transcription factor; Hsp, heat shock protein; MAPK, mitogen-activated protein kinase; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; PDGF, pl
Regulation and functions of sphingosine kinases in the brain
Keywords: ERK، کیناز تنظیم شده خارج سلولی; CNS, central nervous system; DRG, dorsal root ganglion; EGF, epidermal growth factor; EGFR, EGF receptor; ERK, extracellular regulated kinase; E2, 17β-estradiol; FGF, fibroblast growth factor; GDNF, glial-derived nerve growth factor; HIF, hypoxia-inducibl
Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells
Keywords: ERK، کیناز تنظیم شده خارج سلولی; ANOVA, analysis of variance; BSA, bovine serum albumin; DMEM, Dulbecco's modified Eagle's medium; ECAM, endothelial cell adhesion molecule; ECGS, endothelial cell growth supplements; ECL, enhanced chemoluminescence; ERK, extracellular regulated kinase; FB
Respiratory long-term facilitation following intermittent hypoxia requires reactive oxygen species formation
Keywords: ERK، کیناز تنظیم شده خارج سلولی; plasticity; spinal cord; control of breathing; superoxide anionaCSF, artifical cerebrospinal fluid; AIH, acute intermittent hypoxia; BDNF, brain-derived neurotrophic factor; CIH, chronic intermittent hypoxia; ERK, extracellular regulated kinase; i.t., int