Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; Glu, glutamate; Ras, rat sarcoma proto-oncogenic G-protein; MEK, MAPK kinase; ERK, extracellular signal-related kinase; Rheb, RAS homolog enriched in brain; Mnk, MAP kinases phosphorylate; elF4E, eukaryotic initiation factor 4E; 4E-BP, eukaryotic translat
مقالات ISI ERK، kinase مرتبط با سیگنال خارج سلولی (ترجمه نشده)
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Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; (TNF)-α, tumor necrosis factor; ERK, extracellular signal-related kinase; TLR, toll-like receptors (TLRs); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor
Src/Syk/IRAK1-targeted anti-inflammatory action of Torreya nucifera butanol fraction in lipopolysaccharide-activated RAW264.7 cells
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; TNF-α, tumor necrosis factor α; ERK, extracellular signal-related kinase; TLR, Toll-like receptors; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-κB; AP
β-Caryophyllene alleviates d-galactosamine and lipopolysaccharide-induced hepatic injury through suppression of the TLR4 and RAGE signaling pathways
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ALT, alanine aminotransferase; BCP, β-caryophyllene; DAMP, damage-associated molecular patterns; Egr-1, early growth response protein 1; ERK, extracellular signal-related kinase; FHF, fulminant hepatic failure; GalN, d-galactosamine; HBSS, Hank’s balanced
MLK3 regulates fMLP-stimulated neutrophil motility
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; AKT, protein kinase B; AD, accumulated distance; APC, allophycocyanin; CRIB, cdc42/Rac-interactive binding; DMSO, dimethyl sulfoxide; EDTA, ethylenediaminotetraacetic acid; ERK, extracellular signal-related kinase; EtBr, ethidium bromide; FITC, fluorescei
Superantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ERK, Extracellular signal-related kinase; GAPDH, Glyceraldehyde 3-phosphate dehydrogenase; HSL, Hormone sensitive lipase; IL-6R, Interleukin-6 receptor; Iso, Isoprenaline; JAK, Janus activated kinase; PKB, Protein kinase B; RU, Resonance units; SEA, Staph
Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ROS, reactive oxygen species; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; ERK, extracellular signal-related kinase; Nrf2, nuclear-factor-E2-related factor 2; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; ER stress,
Dipterocarpus tuberculatus ethanol extract strongly suppresses in vitro macrophage-mediated inflammatory responses and in vivo acute gastritis
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; Dt-EE, ethanol extract of Dipterocarpus tuberculatus Roxb.; PGE2, prostaglandin E2; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; TNF-α, tumor necrosis factor-α; ERK, extracellular signal-related kinase; TLR, Toll-like receptors; NF-
AP-1 pathway-targeted inhibition of inflammatory responses in LPS-treated macrophages and EtOH/HCl-treated stomach by Archidendron clypearia methanol extract
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; (TNF)-α, tumour necrosis factor; ERK, extracellular signal-related kinase; TLR, Toll-like receptor (TLR); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-
Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ERK, extracellular signal-related kinase; γGCS, γ-glutamylcysteine synthetase; GSH, glutathione; HO-1, heme oxygenase 1; Keap1, Kelch-like ECH associating protein 1; m-CPBA, meta-chloroperoxybenzoic acid; Nrf2, Nuclear factor (erythroid-derived 2)-like 2;
JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; TNF-α, tumor necrosis factor α; ERK, extracellular signal-related kinase; TLR, Toll-like receptors; MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-κB; AP
The inhibitory effect of CIL-102 on the growth of human astrocytoma cells is mediated by the generation of reactive oxygen species and induction of ERK1/2 MAPK
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ERK, extracellular signal-related kinase; Cdks, cyclin-dependent kinases; ROS, reactive oxygen speciesCIL-102; Glioma; G2/M arrest; ROS; ERK; p70S6K
Nod2-Induced Autocrine Interleukin-1 Alters Signaling by ERK and p38 to Differentially Regulate Secretion of Inflammatory Cytokines
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; TLR; IBD; SalmonellaAIEC, adherent invasive Escherichia coli; ATP, adenosine triphosphate; BMDM, bone marrow-derived macrophages; CD, Crohn's disease; ERK, extracellular signal-related kinase; IL, interleukin; IL-1R, interleukin-1 receptor; IL-1Ra, interl
The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; BKCa channels, large-conductance calcium- and voltage-activated potassium channels; EDHF, endothelium-derived hyperpolarizing factor; eNOS, endothelial nitric oxide synthase; ER, estrogen receptor; ERK, extracellular signal-related kinase; GPER, G protein
Enhanced cocaine-conditioned place preference and associated brain regional levels of BDNF, p-ERK1/2 and p-Ser845-GluA1 in food-restricted rats
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; AMPA, α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; DA, dopamine; BDNF, brain-derived neurotrophic factor; ERK, extracellular signal-related kinase; NAc, nucleus accumbens; mPFC, medial prefrontal cortex; dHPC, dorsal hippocampus; FR, food-restricti
Actin cytoskeleton in myofibroblast differentiation: Ultrastructure defining form and driving function
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; α-SMA, α-smooth muscle actin; AKT, AKT/Protein Kinase B; ATP, adenosine triphosphate; ECM, extracellular matrix; EDA, extra domain A; EM, electron microscopy; ERK, extracellular signal-related kinase; FAK, focal adhesion kinase; GEF, guanine exchange fact
Bm-TFF2, a toad trefoil factor, promotes cell migration, survival and wound healing
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; TFF, trefoil factor; ERK, extracellular signal-related kinase; PARP, poly(ADP-ribose) polymerase; EGF, epidermal growth factor; DMEM, Dulbecco’s modified Eagle’s medium; FCS, fetal calf serum; BSA, bovine serum albumin; FITC, fluorescein 5(6)-isothiocyana
Electrochemical study of the intracellular transduction of vascular endothelial growth factor induced nitric oxide synthase activity using a multi-channel biocompatible microelectrode array
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; NO, nitric oxide; NOS, NO synthase; VEGF, vascular endothelial growth factor; L-NAME, NG-nitro-l-arginine methyl ester; MAP, mitogenic-activated protein; ERK, extracellular signal-related kinase; PI-3, phosphatidylinositol 3; PBS, phosphate buffered salin
Effects of (−)-Epicatechin on Myocardial Infarct Size and Left Ventricular Remodeling After Permanent Coronary Occlusion
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; cardioprotection; catechins; flavanols; infarction; ischemiaAKT, protein kinase B; CVD, cardiovascular disease; ERK, extracellular signal-related kinase; IR, ischemia–reperfusion; LV, left ventricle/ventricular; MI, myocardial infarction; PCO, permanent c
In vitro and in vivo anti-inflammatory effects of ethanol extract from Acer tegmentosum
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; (TNF)-α, tumour necrosis factor; ERK, extracellular signal-related kinase; TLR, Toll-like receptors (TLR); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor
Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ANGPTL4, angiopoietin-like 4; HASM, human airway smooth muscle; PKC, protein kinase C; PMA, phorbol-12-myristate-13-acetate; DAG, diacylglycerol; PDGFα, platelet-derived growth factor α; ERK, extracellular signal-related kinase; JNK, Jun N-terminal kinase
Delayed liver injury and impaired hepatocyte proliferation after carbon tetrachloride exposure in BPOZ2-deficient mice
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; BPOZ2, bood POZ containing gene type 2; CCl4, carbon tetrachloride; ERK, extracellular signal-related kinase; STAT3, signal transducer and activator of transcription protein 3; HGF, hepatocyte growth factor; IL-6, interleukin 6; TNF, tumor necrosis factor
Surgical ventricular reconstruction in mice: Elucidating potential targets for combined molecular/surgical intervention
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; EF, ejection fraction; ERK, extracellular signal-related kinase; FS, fractional shortening; JNK, Jun N-terminal kinase; LAD, left anterior descending coronary artery; LV, left ventricle; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricula
Oligomannose-coated liposomes activate ERK via Src kinases and PI3K/Akt in J774A.1 cells
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ERK, extracellular signal-related kinase; MAPK, mitogen-activated protein kinase; PI3K, phosphoinositide-3-kinaseERK; Liposome; Macrophage; MAP kinase; Oligomannose; PI3K; Src family kinases
In vitro and in vivo anti-inflammatory effects of taheebo, a water extract from the inner bark of Tabebuia avellanedae
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PG, prostaglandin; NO, nitric oxide; COX, cyclooxygenase; iNOS, inducible NO synthase; ERK, extracellular signal-related kinase; TLR, Toll-like receptors (TLR); MAPK, mitogen activated protein kinase; NF-κB, nuclear factor-κB; AP-1, activator protein-1; N
Effects of Ile164 Polymorphism of Beta2-Adrenergic Receptor Gene on Coronary Artery Disease
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; beta2-adrenergic receptor; single nucleotide polymorphism; vasodilationAd, adenoviral; AMI, acute myocardial infarction; B2AR, beta2-adrenergic receptor; CAD, coronary artery disease; DNA, deoxyribonucleic acid; ERK, extracellular signal-related kinase; I
The effect of nicotine in vitro on the integrity of tight junctions in Caco-2 cell monolayers
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ERK, Extracellular signal-related kinase; HPLC, High performance liquid chromatography; MAPK, Mitogen activated protein kinase; NFκB, Nuclear factor kappa B; TER, Transepithelial electrical resistance; UC, Ulcerative colitisNicotine; Ulcerative colitis; T
BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; BMP, bone morphogenetic protein; TGFβ, transforming growth factor beta; ERK, extracellular signal-related kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RT-PCR, reverse transcription polymerase chain reaction; DN, dominant negative; JP, juvenile
Insulin-like growth factors control cell migration in health and disease
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; ECM, extracellular matrix; EGF, epidermal growth factor; ER, estrogen receptor; ERK, extracellular signal-related kinase; EVT, extravillous trophoblast; FAK, focal adhesion kinase; FGF, fibroblast growth factor; FN, fibrinectin; KGF, keratinocyte growth f
NF-κB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acid
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; CLA, conjugated linoleic acid; COX-2, cyclooxygenase-2; CAN, conjugated nonadecadienoic acid; DMEM, Dulbecco's Modified Eagle's Medium; EIA, enzyme immunoassay; ERK, extracellular signal-related kinase; FBS, fetal bovine serum; G3PDH, glyceraldehyde-3-pho
Cross-linking of 4-1BB up-regulates IL-13 expression in CD8+ T lymphocytes
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; 4-1BB; IL-13; CD8+ T cells; CalcineurinTNF(R), tumor necrosis factor (receptor); TCR, T cell receptor; ERK, extracellular signal-related kinase; IL-13(R), interlukin-13 (receptor); APC, antigen presenting cell; CsA, cyclosporine A; IFN-γ, interferon-gamma
Cellular functions of cholesterol probed with optical biosensors
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; EGF, epidermal growth factor; EGFR, EGF receptor; ERK, extracellular signal-related kinase; OSBP, oxysterol-binding protein; MAPK, mitogen-activated protein kinase; mβCD, methyl-β-cyclodextrin; RWG, resonant waveguide grating; DMR, dynamic mass redistribu
Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: Roles of calcium, Src, Rho kinase, and the cytoskeleton
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; Ang II, angiotensin II; GPCR, G protein-coupled receptor; LPA, lysophosphatidic acid; MAP kinase, mitogen-activated protein kinase; ERK, extracellular signal-related kinase; PKC, protein kinase C; ROK, Rho-associated kinase; PP2, 4-amino-5-(4-chlorophenyl
Epidermal growth factor affects the synthesis and degradation of type I collagen in cultured human dermal fibroblasts
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; EGF, epidermal growth factor; ECM, extracellular matrix; PMSF, phenylmethylsulfonyl fluoride; ERK, extracellular signal-related kinase; MAPK, mitogen-activated protein kinase; MEK, mitogen-activated protein kinase kinase; MMPs, Matrix metalloproteinasesEG
Parathyroid hormone activates PKC-δ and regulates osteoblastic differentiation via a PLC-independent pathway
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; PTH, parathyroid hormone; PTH1R, PTH/PTHrP receptor; AC, adenylyl cyclase; PLC, phospholipase C; ERK, extracellular signal-related kinase; PKC, protein kinase C; DAG, diacylglycerol; IP3, inositol trisphosphate; PKA, protein kinase A; Epac, exchange prote
The intracellular genistein metabolite 5,7,3′,4′-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; DMSO, dimethyl sulfoxide; ERK, extracellular signal-related kinase; JNK, c-jun N-terminal kinase; MAPK, mitogen-activated protein kinase; PMSF, phenylmethylsulfonyl fluoride; SDS, sodium dodecyl sulfate; THIF, 5,7,3′,4′-tetrahydroxyisoflavoneGenistein; Br
TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells
Keywords: ERK، kinase مرتبط با سیگنال خارج سلولی; TAK1, transforming growth factor-β-activated kinase 1; TAB1, TAK1-binding protein 1; IL-2, interleukin-2; TCR, T cell receptor; MAPK, mitogen-activated protein kinase; JNK, c-Jun NH2-terminal kinase; ERK, extracellular signal-related kinase; MAP3K, MAPK k