دانلود مقالات ISI درباره Erk5 + ترجمه فارسی

تشخیص یک مهارکننده بسیار انتخابی از کینازهای آئورورا

Characterization of a highly selective inhibitor of the Aurora kinases

Keywords: PLK4; Polo-like kinase 4; FACS; fluorescence activated cell sorting; DMSO; dimethylsulfoxide; AML; acute myeloid leukemia; T-ALL; T-cell acute lymphoblastic leukemia; ABL1; Abelson Tyrosine-Protein Kinase 1; LRRK2; Leucine Rich Repeat Kinase 2; BRD4; Brom

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

سیگنالینگ گیرنده نوروتروپین محلی و دراز مدت: اندوسوم ها نه تنها حمل کننده برای حمل آکسون هستند

Local versus long-range neurotrophin receptor signalling: Endosomes are not just carriers for axonal transport

Keywords: Neurotrophins; Signalling endosome; Endosome acidification; Trk receptors; Membrane motility; Receptor internalization; AP-2; adaptor protein complex 2; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; EEA1; early endo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

اضافه بار دوره موجب تنظیم دیافراگماتوگرافی بین موادی گالیالی سیکلاز محلول قلب در هیپرتروفی عصبی و نارسایی قلبی می شود

Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure

Keywords: Cav3; caveolin-3; Cav3+LR; caveolin-3 enriched lipid raft, caveolae; cGMP; cyclic guanosine monophosphate; DEA/NO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate, diethylamine NONOate; ERK5; extracellular signal regulated kinase 5; LR; l

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Neurotrophin-3 provides neuroprotection via TrkC receptor dependent pErk5 activation in a rat surgical brain injury model

Keywords: Surgical brain injury; Brain edema; Neurotrophin 3; Tropomyosin related kinase receptor C; Extracellular signal related kinase 5; SBI; Surgical brain injury; BBB; Blood brain barrier; NT-3; Neurotrophin 3; TrkC; Tropomyosin related kinase receptor C; MAPK

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

The MEK5/ERK5 mitogen-activated protein kinase cascade is an effector pathway of bone-sustaining bisphosphonates that regulates osteogenic differentiation and mineralization

Keywords: ANOVA; analysis of variance; ANT; adenine-nucleotide-translocase; ALPL; alkaline phosphatase; Apppl; ATP analogue triphosphoric acid-1-adenosine-5′yl ester 3-(3-methylbut-3-enyl) ester; BP; bisphosphonate; EC; endothelial cell; eNOS; endothelial nitric

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice

Keywords: Puerarin; Monocyte adhesion; Atherosclerosis; Endothelial cell; ERK5; KLF2;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms

Keywords: ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The platelet phenotype in patients with ST-segment elevation myocardial infarction is different from non-ST-segment elevation myocardial infarction

Keywords: ERK5; extracellular-signal-regulated kinase 5; MI; myocardial infarction; MMP9; matrix metalloproteinase 9; NSTEMI; non-ST-segment myocardial infarction; ROC; receiver operator characteristic; STEMI; ST-segment myocardial infarction;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Mangiferin protects osteoblast against oxidative damage by modulation of ERK5/Nrf2 signaling

Keywords: MAN; Osteoblast; Oxidative damage; ERK5; Nrf2;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration

Keywords: LBP; lower back pain; IVDD; intervertebral disc degeneration; NP; nucleus pulposus; AF; annulus fibrosus; ECM; extracellular matrix; MiRNA; microRNA; BCL2; B-cell lymphoma-2; HUST; Huazhong University of Science and Technology; IVD; intervertebral disc; M

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease

Keywords: COR; C-terminal of Ras; CSF; cerebral spinal fluid; DAT-1; dopamine transporter-1; ERK5; extracellular-signal-regulated kinase 5; ExAC; Exome Aggregation Consortium; GTPase; Guanosine Triphosphate Hydrolase; LoF; loss of function; LRRK2; leucine-rich repe

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Src-family tyrosine kinases and the Ca2 + signal

Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Sub-cellular localization specific SUMOylation in the heart

Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2017 سفارش ترجمه

Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells

Keywords: DDIAS; ERK5; MEF2B; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Lab resourceScutellarin attenuates vasospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats

Keywords: eNOS; Erk5; Scutellarin; Subarachnoid hemorrhage; Vasospasm;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-200b-3p suppresses epithelial-mesenchymal transition and inhibits tumor growth of glioma through down-regulation of ERK5

Keywords: Has-miR-200b-3p (miR-200b-3p); ERK5; Glioma; EMT; Invasion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Mapping the response of human fibroblast growth factor 21 (FGF21) promoter to serum availability and lipoic acid in HepG2 hepatoma cells

Keywords: ACTB; β-actin; CPT1A; carnitine palmitoyltransferase 1α; CBP; CREB binding factor; CREB; cAMP response element-binding protein; DHLA; DL-α-dihydrolipoic acid; Elk-1; ETS domain-containing Elk-1; Elk-4; ETS domain-containing Elk-4 (aka SAP-1); ENCODE; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion

Keywords: DDIAS; DNA damage induced apoptosis suppressor; EGF; epidermal growth factor; MEK5; mitogen-activated protein kinase kinase; ERK5; extracellular signal-regulated kinase 5; MEF2; myocyte enhancer factor 2; hNoxin; human noxin; NFAT; nuclear factor of activ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

Keywords: Oxidative phosphorylation (OXPHOS); Mitochondria; miR-23; ERK5; MEF2; Antioxidant response elements (ARE)

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to Imatinib by regulation of cell cycle and apoptosis-associated members via NF-κB and ERK5 signaling pathway

Keywords: CIAPIN1; K562 cells; Imatinib; ERK5; NF-κB

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleMelatonin exerts protective effect on N2a cells under hypoxia conditions through Zip1/ERK pathway

Keywords: Melatonin; N2a cells; Zip1; ERK1/2; ERK5; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

ERK5 regulates basic fibroblast growth factor-induced type 1 plasminogen activator inhibitor expression and cell proliferation in lung fibroblasts

Keywords: bFGF; ERK5; PAI-1; Fibroblasts; Pulmonary fibrosis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Identification and expression profiles of ERK2 and ERK5 in large yellow croaker (Larimichthys crocea) after temperature stress and immune challenge

Keywords: ERK2; ERK5; Large yellow croaker; Subcellular localization; Temperature stress; Immune challenge

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage

Keywords: MAPK; ERK5; ERK1/2; M-CSFR; Vitamin D; AML;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease

Keywords: αSyn; alpha-synuclein; ALP; autophagy/lysosomal degradation pathway; CSF; cerebral spinal fluid; ERK5; extracellular-signal-regulated kinase 5; IL; interleukin; KI; knock-in; KO; knockout; LPS; lipopolysaccharide; LRRK2; leucine rich repeat kinase 2; MHC

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

ERK 5/MAPK pathway has a major role in 1α,25-(OH)2 vitamin D3-induced terminal differentiation of myeloid leukemia cells

Keywords: 1,25D; 1α,25(OH)2 vitamin D3; AML; acute myeloid leukemia; CC; cell cycle; VDD; vitamin D derivative; BIX; BIX02189; PD; PD98059; U0; U0126; XMD; XMD8-92; Vitamin D derivatives; ERK5; ERK1/2; MAPK inhibitors; Acute myeloid leukemia (AML); Cell differenti

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The role of ERK1, 2, and 5 in dopamine neuron survival during aging

Keywords: Brain; Aging; ERK5; ERK1/2; Striatum; Substantia nigra; Ventral tegmental area; Fischer-344xBrown Norway F1 hybrids (F344xBN F1); MAP kinases;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Statins protect human endothelial cells from TNF-induced inflammation via ERK5 activation

Keywords: AMI; acute myocardial infarction; DCFDA; dihydrodichlorofluorescin diacetate; ECs; endothelial cells; ERK5; extracellular-signal-regulated kinase 5; HAECs; human aortic endothelial cells; HMG CoA; hydroxy-3-methylglutaryl coenzyme A; ICAM-1; intercellular

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Keywords: ERK5 inhibitor; Kinase selectivity; Benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-one; BMK1; big MAP kinase 1; DIEA; N,N-diisopropylethylamine; DCAMKL2; doublecortin and CaM kinase-like 2; DMA; N,N-dimethylacetamide; EGF; epidermal growth factor; ERK5; extrace

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-143 functions as a tumor suppressor in human esophageal squamous cell carcinoma

Keywords: miRNAs, microRNAs; ESCC, esophageal squamous cell carcinoma; NESTs, normal esophageal squamous tissues; ERK-5, extracellular signal regulated kinase-5; MAPK, mitogen-activated protein kinaseEsophageal cancer; microRNA-143; microRNA-145; ERK5; Tumor suppre

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Extracellular-regulated-kinase 5-mediated renal protection against ischemia–reperfusion injury

Keywords: MAPK; ERK5; Western blot; Mobility shift; Viral transduction; IR injury

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Myocyte enhancer factor 2 (MEF2) tethering to muscle selective A-kinase anchoring protein (mAKAP) is necessary for myogenic differentiation

Keywords: mAKAP; muscle specific A-kinase anchoring protein; MEF2; myocyte enhancer factor 2; PKA; protein kinase A; PDE4D3; phosphodiesterases type 4D3; ERK5; big mitogen-activated protein kinase; GFP; green fluorescent protein; NFAT; nuclear factor of activated T

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes

Keywords: GEnC, glomerular endothelial cells; GFB, glomerular filtration barrier; llLSS, laminar shear stress; EnC, endothelial cell; KLF2, Kruppel-like factor 2; TM, thrombomodulin; VASP, vasodilator-stimulated phosphoproteinLaminar shear stress; Glomerulus; ERK5;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs)

Keywords: MAPK; ERK5; p21; p27; CDK; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

MEK5/ERK5 pathway: The first fifteen years

Keywords: Mitogen-activated protein kinase; Big-mitogen activated protein kinase; Erk5; Cellular signaling; Epithelial-to-mesenchymal transition; Kinase inhibitors

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of MEK5 by BIX02188 induces apoptosis in cells expressing the oncogenic mutant FLT3-ITD

Keywords: FLT3; MEK5; ERK5; Apoptosis; Proliferation; Receptor tyrosine kinase; Acute myeloid leukemia;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

MEK5/ERK5/mef2: A novel signaling pathway affected by hepatitis C virus non-enveloped capsid-like particles

Keywords: HCVne; Hepatitis C non-enveloped capsid-like particles; EGF; epidermal growth factor; MAPKs; Mitogen Activated Protein Kinases; UO126; Selective inhibitor of both MEK1 and MEK2; PD98059; Specific inhibitor of the activation of mitogen-activated protein ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells

Keywords: Bladder cancer; MicroRNA-143; Tumor suppressor; ERK5; AktmRNA, messenger RNA; cDNA, complementary DNA; PCR, polymerase chain reaction; siRNA, small interfering RNA; UTR, untranslated region; RISC, RNA-induced silencing complex; Ago2, Argonaute 2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation

Keywords: MAPK; ERK1/2; JNK; p38; ERK5; Nuclear translocation

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway

Keywords: MEK5; ERK5; Inhibitor; Benzimidazole

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Structure-activity relationships of benzimidazole-based selective inhibitors of the mitogen activated kinase-5 signaling pathway

Keywords: MEK; MEK5; ERK; ERK5; Benzimidazole; Hoechst 33258;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Hypertrophic response to angiotensin II is mediated by protein kinase D-extracellular signal-regulated kinase 5 pathway in human aortic smooth muscle cells

Keywords: Angiotensin II; PKD; ERK5; Human aortic smooth muscle cells; Hypertrophy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

ERK1/2, but not ERK5, is necessary and sufficient for phosphorylation and activation of c-Fos

Keywords: ERK1/2; ERK5; Fos; JNK; Jun; MEF2D; p38

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells

Keywords: MiRNA-143; Apoptosis; Fas; Jurkat T-cell; ERK5;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of pharmacological inhibitors of the MEK5/ERK5 pathway

Keywords: MEK5; ERK5; Kinase inhibitors; Pharmacological inhibitors

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5

Keywords: DUSP6; ERK1/2; ERK5; MKP-3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells

Keywords: BMK1; Cell migration; Cell proliferation; ERK5; Hepatic fibrosis; Hepatic stellate cells; Mitogen-activated protein kinase; MAPK7; Platelet-derived growth factor; Signal transduction

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Research ReportThe activation of extracellular signal-regulated protein kinase 5 in spinal cord and dorsal root ganglia contributes to inflammatory pain

Keywords: MAPKs; mitogen-activated protein kinases; ERK5; extracellular signal-regulated protein kinase 5; DRG; dorsal root ganglion; CFA; complete Freund's adjuvant; CREB; cAMP response-element binding protein; ERK1/2; extracellular signal-regulated kinase 1/2; JN

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells

Keywords: ERK5; Insulin; Angiotensin-II; Vascular smooth muscle cells; MEF2C;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway

Keywords: Grifolin; Cell cycle; ERK1/2; ERK5

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه