Keywords: Antiproliferative activity; Diarylamide; Diarylurea; ERK kinase; Melanoma; Quinoline;
مقالات ISI (ترجمه نشده)
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Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
Keywords: Mitogen-activated protein kinases; Extracellular signal-regulated kinase; ERK inhibitor; ERK kinase; Cancer therapy; Drug resistance;
Neurosteroid metabolites of testosterone and progesterone differentially inhibit ERK phosphorylation induced by amyloid β in SH-SY5Y cells and primary cortical neurons
Keywords: Allopregnanolone; Androstanediol; Neuroprotection; ERK kinase; GABA; Amyloid; Neurosteroids;
Monoamine receptor agonists, acting preferentially at presynaptic autoreceptors and heteroreceptors, downregulate the cell fate adaptor FADD in rat brain cortex
Keywords: FADD and p-FADD; FLIP-L; Monoamine depletion; Monoamine receptor agonists and antagonists; MEK-ERK signaling; Neuroplasticity; AMPT; α-methyl-DL-p-tyrosine; ANOVA; analysis of variance; DISC; death inducing signaling complex; DMSO; dimethyl sulfoxide;
Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice
Keywords: DRGs; dorsal root ganglia; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; GAPDH; glyceraldehyde3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; IBA-1; ionized calcium binding adapter molecule 1; IL-1β; interleukin-1
Crosstalk between cdk5 and MEK-ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain
Keywords: BCA; bicinchoninic acid; cAMP; cyclic AMP; cdk5; cyclin-dependent kinase 5; ctx; cerebral cortex; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of 32Â kDa; DMSO; dimethyl sulphoxide; ECL; enhanced chemiluminescence; ERK; extracellular signal-regul
Berberine acutely activates the glucose transport activity of GLUT1
Keywords: Berberine; Glucose uptake; GLUT1; ERK kinase; AMPK
New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studies
Keywords: 1,3,4-Triarylpyrazole; Melanoma; Diarylurea; Diarylamide; B-RAF kinase; ERK kinase
Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening
Keywords: MPTP; Pioglitazone; Rosiglitazone; Ciglitazone; Troglitazone; Amplex Red; KNIME; MOE-Dock; ERK kinase; PPAR-γ
Involvement of ORL1 receptor and ERK kinase in the orphanin FQ-induced nociception in the nucleus accumbens of rats
Keywords: Orphanin FQ (OFQ); Nociception; Opioid receptor-like (ORL1) receptor; Nucleus accumbens (NAc); ERK kinase; Hindpaw withdrawal latency;
Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner
Keywords: Metallothionein-III; Heme oxygenase-1; NF-E2 related factor 2; Phosphatidylinositol 3-kinase; ERK kinase; neuroprotection; Parkinson's disease
In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)?
Keywords: ALK, Anaplastic Lymphoma Kinase; RPTPβ, Receptor Tyrosine Phosphatase Beta; mAb, monoclonal antibody; Pleiotrophin, Pleiotrophin; FN, Fibronectin.ALK; Pleiotrophin; ERK kinase; Glioblastoma; Neuroblastoma