
Design and synthesis of new potent anticancer benzothiazole amides and ureas featuring pyridylamide moiety and possessing dual B-RafV600E and C-Raf kinase inhibitory activities
Keywords: Anticancer activity; Benzothiazole; Urea; Amide; Pyridylamide; B-RafV600E; C-Raf; ATCC; American tissue culture collection; CDI; 1,1'-carbonyldiimidazole; CLogP; Calculated LogP (Partition coefficient); DIPEA; N,N-diisopropylethylamine; DTT; Dithiothreito