دانلود مقالات ISI درباره F508Del-Cftr + ترجمه فارسی

Therapeutic approaches to CFTR dysfunction: From discovery to drug development

Keywords: CFTR Cl− channel; F508del-CFTR; CFTR correctors; Pharmacological chaperones; Proteostasis regulators, artificial anion transporters (anionophores);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Resolvin D1 regulates epithelial ion transport and inflammation in cystic fibrosis airways

Keywords: Resolvin D1; Airway surface liquid layer; ENaC; F508del-CFTR; CF mice; CF alveolar macrophages;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Calumenin contributes to ER-Ca2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; ER; endoplasmic reticulum; CF; cystic fibrosis; SERCA; sarco/endoplasmic reticulum Ca2+ ATPase; PMCA; plasma membrane Ca2+ ATPase; TG; thapsigargin; F508del-CFTR; Calumenin; SERCA; ER Ca2+ homeost

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

SERCA and PMCA pumps contribute to the deregulation of Ca2 + homeostasis in human CF epithelial cells

Keywords: F508del-CFTR; PMCA; SERCA; Cystic fibrosis; Calcium signaling

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo

Keywords: Cystic fibrosis; F508del-CFTR; Modulators; Activators; Salivary secretion; Docking; Nucleotide binding domainsCF, cystic fibrosis; CFTR, cystic fibrosis transmembrane conductance regulator; CHO cells, Chinese hamster ovaries cells; CMGD, cyclic methylglyo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Evidence for alteration of calpain/calpastatin system in PBMC of cystic fibrosis patients

Keywords: CF, cystic fibrosis; CFTR, cystic fibrosis transmembrane conductance regulator; NHERF, Na+/H+ exchanger 3 regulatory factor; PBMC, peripheral blood mononuclear cellsCFTR; F508del-CFTR; Ca2+-dependent proteolysis; Calpain; NHERF-1; Ezrin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Dysfunction of mitochondria Ca2+ uptake in cystic fibrosis airway epithelial cells

Keywords: Ca2+ signalling; F508del-CFTR; Pharmacology; Mitochondria; Cystic fibrosis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Low temperature restoring effect on F508del-CFTR misprocessing: A proteomic approach

Keywords: F508del-CFTR; Low temperature; Protein trafficking; Therapeutic targets

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR

Keywords: Cystic fibrosis; Calcium signalling; Pharmacology; F508del-CFTR; Trafficking; Miglustat;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه