دانلود مقالات ISI درباره Fingolimod + ترجمه فارسی

q-Space Myelin Map imaging for longitudinal analysis of demyelination and remyelination in multiple sclerosis patients treated with fingolimod: A preliminary study

Keywords: Multiple sclerosis; Fingolimod; Remyelination; MRI; q-Space Myelin Map;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Acute onset of fingolimod-associated macular edema

Keywords: Fingolimod; Macular edema; Carbonic anhydrase inhibitor; Intermediate uveitis; Multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)

Keywords: Sphingosine-1-phosphate; Sphingosine-1-phosphate 1; S1P1; Isoxazole; FTY720; Fingolimod;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod-induced leukoencephalopathy in a patient with neuromyelitis optica spectrum disorder

Keywords: Multiple sclerosis; Neuromyelitis optica spectrum disorder; Fingolimod; Leukoencephalopathy; MRI;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Mixed hemimicelles solid-phase extraction based on sodium dodecyl sulfate (SDS)-coated nano-magnets for the spectrophotometric determination of Fingolomid in biological fluids

Keywords: Fingolimod; Magnetic solid-phase extraction; Mixed-hemimicelles; Iron nanoparticles

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportFingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia

Keywords: Stroke; FTY720; Fingolimod; LTP; Sphingosine-1-phosphate;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Update on the cardiovascular profile of fingolimod in the therapy of relapsing-remitting multiple sclerosis (MS)

Keywords: Cardiovascular profile; Fingolimod; Relapsing-remitting; Multiple sclerosis (MS);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod ameliorates the development of experimental autoimmune encephalomyelitis by inhibiting Akt–mTOR axis in mice

Keywords: Multiple sclerosis; Experimental autoimmune encephalomyelitis; Fingolimod; mTOR; Treg cell; Th1 cell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The effectiveness of fingolimod in a Portuguese real-world population

Keywords: Multiple Sclerosis; Fingolimod; Relapsing/remitting; Second line treatment; Treatment Response; Outcome measurement

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A high throughput flow gradient LC–MS/MS method for simultaneous determination of fingolimod, fampridine and prednisone in rat plasma, application to in vivo perfusion study

Keywords: Polytherapy; Fingolimod; Fampridine; Phase 4; Multiple sclerosis; Pharmacokinetics; Perfusion

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatitis C virus (HCV) reactivation during fingolimod treatment for relapsing and remitting multiple sclerosis

Keywords: Fingolimod; Multiple sclerosis; Hepatitis C virus; Reactivation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod therapy modulates circulating B cell composition, increases B regulatory subsets and production of IL-10 and TGFβ in patients with Multiple Sclerosis

Keywords: Autoimmunity; B cell subsets; Cytokine; Fingolimod; Multiple sclerosis; Regulatory cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia

Keywords: Neonatal brain injury; Hyperoxia; Oligodendrocyte; White matter development; Fingolimod;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Research PaperThe multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration

Keywords: Fingolimod; FTY720; Multiple sclerosis; IEG; c-Fos; SRF; Sphingosine; Neurite growth; Growth cone; Axon regeneration; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Impact of a switch to fingolimod on depressive symptoms in patients with relapsing multiple sclerosis: An analysis from the EPOC (Evaluate Patient OutComes) trial

Keywords: BDI-II; Depression; Fingolimod; Multiple sclerosis; Patient-reported outcomes; Satisfaction;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiovascular effects of fingolimod: Relevance, detection and approach

Keywords: Multiple sclerosis; Fingolimod; Bradycardia; Atrioventricular block; Heart rateEsclerose múltipla; Fingolimod; Bradicardia; Bloqueio auriculoventricular; Frequência cardíaca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiovascular effects of fingolimod: Relevance, detection and approach

Keywords: Multiple sclerosis; Fingolimod; Bradycardia; Atrioventricular block; Heart rateEsclerose múltipla; Fingolimod; Bradicardia; Bloqueio auriculoventricular; Frequência cardíaca

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Fingolimod does not enhance cerebellar remyelination in the cuprizone model

Keywords: S1P; sphingosine 1-phosphate; Wr; weeks of recovery; β-APP; amyloid β precursor protein; IHC; immunohistochemistry; PL; Purkinje layer; GL; granule layer; FTY720; Fingolimod; Cuprizone; Cerebellum; Demyelination; Remyelination;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Effets indésirables oculaires des traitements systémiques : une mise à jour

Keywords: Effets indésirables oculaires; Thérapies ciblées anticancéreuses; Interféron; Étanercept; Fingolimod; Biphosphonate; Inhibiteurs de la phosphodiestérase; Topiramate; Nicorandil; Ocular adverse effects; Cancer target therapy; Fingolimod; Etanercept;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Sphingosine 1-phosphate signaling at the blood–brain barrier

Keywords: sphingosine 1-phosphate; blood–brain barrier; fingolimod; multiple sclerosis; neuroinflammation; astrocyte

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Fingolimod treatment promotes proliferation and differentiation of oligodendrocyte progenitor cells in mice with experimental autoimmune encephalomyelitis

Keywords: MS; multiple sclerosis; CNS; central nervous system; S1P; sphingosine 1-phosphate; BBB; blood-brain barrier; OPC; oligodendrocyte progenitor cell; Shh; sonic hedgehog; Smo; smoothened; EAE; experimental autoimmune encephalomyelitis; PLP; myelin proteoli

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Forced degradation of fingolimod: Effect of co-solvent and characterization of degradation products by UHPLC-Q-TOF-MS/MS and 1H NMR

Keywords: Fingolimod; UHPLC stability assay; Forced degradation; Stress studies; LC-MS/MS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Use of fingolimod in patients with relapsing remitting multiple sclerosis in Kuwait

Keywords: Multiple sclerosis; Fingolimod; Treatment; Outcome measures;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Short communicationChanges in Th17 and regulatory T cells after fingolimod initiation to treat multiple sclerosis

Keywords: Th17; Interleukin-17; Regulatory T cells; Multiple sclerosis; Fingolimod; Treatment;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Tumefactive demyelination and a malignant course in an MS patient during and following fingolimod therapy

Keywords: Multiple sclerosis; Immune-suppression; Side effects; Therapy; Fingolimod; Tumefective

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Research reportFingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment

Keywords: oAβ; oligomeric amyloid β; BDNF; brain-derived neurotrophic factor; NORT; novel-object recognition test; S1P; sphingosine-1-phosphate; S1PR; sphingosine-1-phosphate receptor; Trk; tropomyosin-related kinase; Fingolimod; Alzheimer's disease; Amyloid β;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Nuestra experiencia con fingolimod

Keywords: Bradicardia; Esclerosis múltiple remitente recurrente; Fingolimod; Seguridad cardiológica; Bradycardia; Relapsing Remitting Multiple Sclerosis; Fingolimod; Cardiac safety;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Investigation of immune and CNS-mediated effects of fingolimod in the focal delayed-type hypersensitivity multiple sclerosis model

Keywords: Blood-brain barrier; Central nervous system; Delayed-type hypersensitivity model; Fingolimod; Lesion; Multiple sclerosis; BBB; blood-brain barrier; BCG; bacillus Calmette-Guérin; CNS; central nervous system; DTH; delayed-type hypersensitivity; DTPA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Cost minimisation analysis of fingolimod vs. natalizumab as a second line of treatment for relapsing-remitting multiple sclerosis

Keywords: Relapsing-remitting multiple sclerosis; Efficiency; Cost minimisation analysis; Fingolimod; Natalizumab; Spain; Esclerosis múltiple remitente-recurrente; Eficiencia; Minimización costes; Fingolimod; Natalizumab; España;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Análisis de minimización de costes entre fingolimod y natalizumab en segunda línea de tratamiento de esclerosis múltiple remitente-recurrente

Keywords: Esclerosis múltiple remitente-recurrente; Eficiencia; Minimización costes; Fingolimod; Natalizumab; EspañaRelapsing-remitting multiple sclerosis; Efficiency; Cost minimisation analysis; Fingolimod; Natalizumab; Spain

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Treatment with the Immunomodulator FTY720 (Fingolimod) Significantly Reduces Renal Inflammation in Murine Unilateral Ureteral Obstruction

Keywords: kidney; ureteral obstruction; fingolimod; inflammation; fibrosisCXCL1, chemokine (C-X-C motif) ligand 1; EMT, epithelial-mesenchymal transition; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IL, interleukin; MCP-1, monocyte chemoattractant protein-1; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Impact of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod: Subgroup analyses of the Fingolimod Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis (FREEDOMS) study

Keywords: Disease-modifying therapy; Fingolimod; Multiple sclerosis; Sphingosine 1-phosphate receptor modulator; Treatment history; Relapse rate;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Effect of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod vs. interferon β-1a intramuscular: Subgroup analyses of the Trial Assessing Injectable Interferon vs. Fingolimod Oral in Relapsing-Remitting Multipl

Keywords: Disease-modifying therapy; Fingolimod; Interferon; Multiple sclerosis; Sphingosine 1-phosphate receptor modulator; Relapse rate;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

First-dose effects of fingolimod after switching from injectable therapies in the randomized, open-label, multicenter, Evaluate Patient OutComes (EPOC) study in relapsing multiple sclerosis

Keywords: Multiple sclerosis; Fingolimod; First-dose effects; Transient bradycardia; Patient outcomes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Fingolimod in relapsing multiple sclerosis: An integrated analysis of safety findings

Keywords: AV; atrioventricular; FREEDOMS; FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis; HPS; haemophagocytic syndrome; LRTI; lower respiratory tract infection; MS; multiple sclerosis; PML; progressive multifocal leukoencephalopathy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Outcomes of switching directly to oral fingolimod from injectable therapies: Results of the randomized, open-label, multicenter, Evaluate Patient OutComes (EPOC) study in relapsing multiple sclerosis

Keywords: Fingolimod; Multiple sclerosis; Satisfaction; Fatigue; Depression

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Second generation S1P pathway modulators: Research strategies and clinical developments

Keywords: Immunomodulator; S1P modulator; S1P1; Fingolimod

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice

Keywords: Fingolimod; ST-968; ST-1071; Sphingosine 1-phosphate; Endothelial cells; Permeability; Multiple sclerosis; AUC; area under the curve; BBB; blood brain barrier; BSA; bovine serum albumin; CHO; Chinese hamster ovary; DMEM; Dulbecco's modified Eagle medium;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis

Keywords: Sphingosine-1-phosphate; B cells; migration; autoimmunity; circulation; fingolimod; FTY720; primary immunodeficiencies; ALL; Acute lymphoblastic leukemia; B-CLL; B-cell chronic lymphocytic leukemia; BCR; B-cell receptor; BFP; Blue fluorescent protein; BTK

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2014 سفارش ترجمه

Varicella vaccination after fingolimod: A case report

Keywords: Fingolimod; Multiple sclerosis; Varicella zoster virus; Shingles; Varicella zoster vaccine; Immunosuppression;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

HDL drug carriers for targeted therapy

Keywords: HDL; high-density lipoprotein; SR-BI; scavenger receptor class B type I; eNOS; endothelial nitric oxide synthase; miRNAs; microRNAs; S1PRs; sphingosine 1-phosphate receptors; S1P; sphingosine 1-phosphate; PGI2; prostaglandin I2; COX-2; cyclooxygenase-2; F

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Fingolimod: Direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy

Keywords: S1P; Fingolimod; Experimental autoimmune encephalitis; Multiple sclerosis; Neuroprotection; Sphingosine 1-phosphate receptor modulator; Lysophospholipids;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage

Keywords: Intracerebral hemorrhage; Fingolimod; Lymphocyte; Inflammation; Neuroprotection; Brain edema; Behavior;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Rebound exacerbation multiple sclerosis following cessation of oral treatment

Keywords: Multiple sclerosis; Fingolimod; BG12; Rebound

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Fingolimod phosphate promotes the neuroprotective effects of microglia

Keywords: Fingolimod; Microglia; Pro-inflammatory cytokine; Neurotrophic factor; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of efficacy, safety and tolerability of fingolimod in patients with the relapsing form of multiple sclerosis – 12-month observation. A preliminary report

Keywords: fingolimod; multiple sclerosis – relapsing-remitting form (RRMS)fingolimod; stwardnienie rozsiane – postać rzutowo-remisyjna (RRMS)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Nuevos tratamientos para la esclerosis múltiple

Keywords: Esclerosis múltiple; Alemtuzumab; Cladribina; Daclizumab; Dalfampridina; Dimetil fumarato; Fingolimod; Laquinimod; Rituximab; TeriflunomidaMultiple sclerosis; Alemtuzumab; Cladribine; Daclizumab; Dalfampridine; Dimethyl fumarate; Fingolimod; Laquinimod; R

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The structure and function of the S1P1 receptor

Keywords: sphingosine 1-phosphate receptor; receptor structure; fingolimod; FTY720; multiple sclerosis

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Visual Issues in Multiple Sclerosis

Keywords: Diplopia; Fingolimod; Internuclear ophthalmoplegia; Multiple sclerosis; Nystagmus; Optic neuritis; Optical coherence tomography;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis of novel therapeutic agents for the treatment of multiple sclerosis: A brief overview

Keywords: Multiple sclerosis; T- and B-lymphocytes; Fingolimod; Laquinimod; Cladribine; TeriflunomideMS, multiple sclerosis; CNS, central nervous system; RRMS, relapsing remitting MS; PPMS, primary progressive MS; SPMS, secondary progressive MS; PRMS, progressive r

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه