Keywords: Synthesis; 4-Phenoxypyridine derivatives; 1,8-Naphthyridinone; Antiproliferative activity; c-Met; Flt-3;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Acute Myeloid Leukemia; BCL-2; c-KIT; FLT-3; Real-time PCR;
Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety
Keywords: Synthesis; Pyrrolo[2,3-b]pyridine derivatives; 1,8-Naphthyridin-2-one; Antiproliferative activity; c-Met; Flt-3;
Sorafenib: A potential therapeutic drug for hepatic fibrosis and its outcomes
Keywords: NAFLD; Non-alcoholic fatty liver disease; NASH; Non-alcoholic steatohepatitis3; ECM; Extracellular matrix; VEGF-R; Vascular endothelial growth factor receptor; PDGF-R; Platelet-derived growth factor receptor; c-KIT; c-kit proto-oncogene protein; FLT-3; FM
Impact of chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) on cancer treatment outcomes: An overview about well-established and recently emerging clinical data
Keywords: ABCC1/MRP; ATP binding cassette subfamily C member 1/ multidrug resistance protein; ABVD; doxorubicine-bleomycin-vinblastine-dacarbazine; AC; doxorubicin-cyclophosphamide; ANC; absolute neutrophil count; ASCO; American Society of Clinical Oncology; AUC; a
Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents
Keywords: Multiple receptor tyrosine kinase inhibitors; Antiangiogenic agents; Pyrimido[4,5-b]indole synthesis; Thymidylate synthase inhibitors; Combination chemotherapeutic potential in single agents; RTK; receptor tyrosine kinases; VEGF; vascular endothelial grow
Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis
Keywords: Dermatomyositis; Interstitial lung disease; Cytokine; Chemokine CX3CL1; Ab; antibody; ADM; amyopathic dermatomyositis; CT; computed tomography; CX3CL1; chemokine (C-X3-C motif) ligand 1; EGF; epidermal growth factor; FGF-2; fibroblast growth factors-2; Fl
Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics
Keywords: Breast cancer; Receptor tyrosine kinase; Small molecule inhibitor; Senescence; Polyploidy; mTOR signaling; Chemosensitivity; AXL; Greek word anexelekto; BCR; breakpoint cluster region; BRAF; B-Rapidly Accelerated Fibrosarcoma; DAPI; 4â²,6â²-diamidino-2-
Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia
Keywords: Leukemia; Aurora B; FLT-3; Acyluriedoindolin-2-one; Inhibitors; Structure–activity relationshipAML, acute myeloid leukemia; FLT3, faline McDonough sarcoma like tyrosine kinase 3; RTK, receptor tyrosine kinase; ITD, internal tandem duplication; ATP, adenin
Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor
Keywords: Aurora B; Kinase inhibitor; Indolin-2-one; Anticancer; Structure–activity relationshipFasL, Fas ligand; TEA, triethylamine; VEGFR, vascular endothelial growth factor; PDGFR, platelet-derived growth factor receptor; c-Met, MNNG HOS-transforming gene; Flt-3
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Keywords: PIM inhibitors; Scaffold hopping; Triazolopyridine; Hit to lead; Phosphorylation of BAD; FLT-3; Crystal structure; Docking; hERG Binding; Mechanism of action
Modification of a promiscuous inhibitor shifts the inhibition from γ-secretase to FLT-3
Keywords: Acute myeloid leukemia; FLT-3; Kinase inhibitor; γ-Secretase;
N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: Design, synthesis, and in vivo evaluation
Keywords: ATP; adenosine 5â²triphosphate; VEGF; vascular endothelial growth factor; EGF; epidermal growth factor; PDGF; platelet derived growth factor; RTK; receptor tyrosine kinase; KDR; kinase insert domain receptor; VEGFR-2; vascular endothelial growth factor r
Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors
Keywords: Azulene; FMS-like tyrosine kinase 3; FLT-3; Acute myeloid leukemia; AML
Plasma levels of FL and SDF-1 and expression of FLT-3 and CXCR4 on CD34+ cells assessed pre and post hematopoietic stem cell mobilization in patients with hematologic malignancies and in healthy donors
Keywords: PBSC; FLT-3; SDF-1; CXCR4; Adhesion molecules; Mobilization; CD34+ cells
Treatment of relapsed or refractory acute promyelocytic leukemia
Keywords: acute promyelocytic leukemia; arsenic trioxide; gemtuzumab ozogamicin; FLT-3; hematopoietic stem cell transplantation; autologous transplant; allogeneic transplant
Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases
Keywords: Kinase inhibitor; Oxazepine; FLT-3; Aurora
FLT-3: a new focus in the understanding of acute leukemia
Keywords: FLT-3; Leukemia; Targeted therapy;