Keywords: PTZ; pentylenetetrazol; SE; status epilepticus; KD; ketogenic diet; ND; normal control diet; FJB; Fluoro-jade B; MOMP; mitochondrial out-membrane permeabilization; mTOR; mammalian target of rapamycin; RAP; rapamycin; 3-MA; 3-methyladenine; ATG 5; autophag
مقالات ISI (ترجمه نشده)
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Keywords: TLE; temporal lobe epilepsy; SE; status epilepticus; CA1; Cornus Ammonis 1; DG; dentate gyrus; FJB; Fluoro-Jade B; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding adaptor molecule 1; EEG; electroencephalogram; SBDPs; α-spectrin brea
Keywords: TBI; Traumatic brain injury; TAI; traumatic axonal injury; CSF; cerebrospinal fluid; HI; hypoxic-ischemia; eCCI; electronically driven controlled cortical impact; PBS; phosphate-buffered saline; FJB; fluoro-jade B; Iba1; anti-ionized calcium-binding adapt
Keywords: ANOVA; analysis of variance; CCI; controlled cortical impact; FJB; fluoro-jade B; iNOS; inducible nitric oxide synthase; MWM; Morris water maze; NO; nitric oxide; PYC; pycnogenol; TBI; traumatic brain injury; Bioflavonoids; Head injury; Natural compounds;
Keywords: Morphine dependence; Ventral tegmental area; Substantia nigra; TH-positive cell; Fluoro-Jade B
Keywords: AGE; glycation end products; CV; cresyl violet; DAPI; 4â²,6-diamidino-2-phenylindole; DCF-DA; 2â²,7â²-dichlorofluorescein diacetate; F-JB; Fluoro-Jade B; GLO; glyoxalase; IPTG; isopropyl-β-D-thiogalactoside; JNK; c-Jun N-terminal kinase; MAPK; mitogen
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ANOVA; Analysis of variance; Aβ; amyloid β; bHLH; basic Helix-Loop-Helix; C4; complement C4; CLEAR; coordinated lysosomal expression and regulation; Cyba; cytochrome b-245 light chain; DW; d
Keywords: EDTA; ethylenediaminetetraacetic acid; FJB; Fluoro-Jade B; HSF1; heat shock factor 1; HSP; heat shock protein; PB; phosphate buffer; PBS; phosphate-buffered saline; PC; piriform cortex; SE; status epilepticus; HSP70; HSP90; epilepsy; priform cortex; hippo
Keywords: CD11b+; CD11b-positive; CNS; central nervous system; DG; dentate gyrus; EC; entorhinal cortex; EtOH; ethanol-treated; Morris water maze; MWM; Novel object recognition; NOR; FJB; Fluoro-Jade B; FJB+; FJB-positive; BrdU+; BrdU-positive; PBS; phosphate buffe
Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus
Keywords: AD; Alzheimer's disease; CA1; hippocampal Cornu Ammonis 1 area; ERK 1/2; extracellular signal-regulated protein kinases 1/2; F-J B; Fluoro-Jade B; IVD; ischemic vascular dementia; MBP; myelin basic protein; p-ERK1/2; phospho-ERK1/2; tGCI; transient gl
7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo
Keywords: Behavioural experiment; Electrophysiology; Glutamate receptor; Human pathogenic mutation; Ion channel; Pharmacology; AD; Alzheimer's disease; AMPA; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; ANOVA; Analysis of Variance; CAS; Czech Academy o
PKA-CREB-BDNF signaling pathway mediates propofol-induced long-term learning and memory impairment in hippocampus of rats
Keywords: cAMP; cyclic adenosine 3â²,5â² monophosphate; PKA; protein kinase A; CNS; central nervous system; CREB; cAMP response element-binding protein; BDNF; brain-derived neurotrophic factor; FJB; Fluoro-Jade B; MWM; Morris water maze; NeuN; neuronal nuclei ant
Critical role for Annexin A7 in secondary brain injury mediated by its phosphorylation after experimental intracerebral hemorrhage in rats
Keywords: ANXA7; Annexin A7; FJB; fluoro-jade B; ICH; intracerebral hemorrhage; NMDA receptor; N-methyl-d-aspartate receptor; PSD95; postsynaptic density protein 95; SBI; secondary brain injury; SD; Sprague Dawley; SNAP23; Synaptosome associated protein 23; SNAP25;
Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-β activated kinase-1 binding protein-1 signaling pathway
Keywords: COX-2; cyclooxygenase-2; DAPI; 4,6-diamino-2-phenyl indole; DHA; docosahexaenoic acid; EBI; early brain injury; EMSA; electrophoretic mobility shift assays; EPA; eicosapentaenoic acid; FJB; Fluoro-Jade B; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G
5-HT2C serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice
Keywords: EDTA; ethylenediaminetetraacetic acid; fEPSPs; field excitatory postsynaptic potentials; GSK-3β; glycogen synthase kinase-3β; FJB; fluoro-jade B; GFAP; glial fibrillary acidic protein; HFS; high frequency stimulation; 5-HIAA; 5-hydroxyindoloacetic acid;
Ischemic preconditioning protects hippocampal pyramidal neurons from transient ischemic injury via the attenuation of oxidative damage through upregulating heme oxygenase-1
Keywords: CO; carbon monoxide; CV; Cresyl violet; F-J B; Fluoro-Jade B; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxygenase-1; IPC; ischemic preconditioning; 8-OhdG; 8-hydroxy-2â²-deoxyguanosine; ROS; reactive oxygen species; ZnPP; zinc protoporphyrin IX.; Ischemiaâ
PSD-93 deletion inhibits Fyn-mediated phosphorylation of NR2B and protects against focal cerebral ischemia
Keywords: ACSF; artificial cerebrospinal fluid; co-IP; co-immunoprecipitation; EPSP; excitatory postsynaptic potential; FJB; fluoro-Jade B; i-LTP; ischemic long term potentiation; KO; knockout; MAGUK; membrane-associated guanylate kinase family; MCAO; middle cerebr
Hesperidin pretreatment protects hypoxia-ischemic brain injury in neonatal rat
Keywords: BBB; blood-brain barrier; DCFH-DA; 2â²,7â²-dichlorodihydro-fluorescein diacetate; DIV; days in vitro; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; FJB; fluoro-jade B; HI; hypoxia-ischemic; HIE; hypoxia-ischemic encephalopath
Periadolescent ethanol vapor exposure persistently reduces measures of hippocampal neurogenesis that are associated with behavioral outcomes in adulthood
Keywords: ANOVA; analysis of variance; BECs; blood ethanol concentrations; BrdU; Bromo-deoxy-Uridine; DCX; doublecortin; DG; hippocampal dentate gyrus; DTI; diffusion tensor imaging; FJB; Fluoro-Jade B; FST; forced swim test; GCL; granule cell layer; IHC; immunohis
Research ReportBi-lateral changes to hippocampal cholesterol levels during epileptogenesis and in chronic epilepsy following focal-onset status epilepticus in mice
Keywords: EEG; electroencephalographic; FJB; Fluoro-Jade B; KA; kainic acid; TUNEL; terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end-labeling; Brain; Kainic acid; Seizure; Chronic epilepsy; Cholesterol; Statins;
Combined diazepam and HDAC inhibitor treatment protects against seizures and neuronal damage caused by soman exposure
Keywords: Suberoylanilide hydroxamic acid; Valproic acid; Fluoro-Jade B; Hippocampus; Amygdala; Thalamus; Piriform; Cortex; Soman;
Research ReportNeuronal degeneration and gliosis time-course in the mouse hippocampal formation after pilocarpine-induced status epilepticus
Keywords: Epilepsy; Status epilepticus; Pilocarpine; Fluoro-jade B; Neurodegeneration; Astrocyte;
Comparison of immunoreactivities in 4-HNE and superoxide dismutases in the cervical and the lumbar spinal cord between adult and aged dogs
Keywords: Aging; Reactive oxygen species; Lipid peroxidation; NeuN; Fluoro-Jade B; SOD1; SOD2
Role of activating transcription factor 3 in ischemic penumbra region following transient middle cerebral artery occlusion and reperfusion injury
Keywords: Activating transcription factor 3; Cerebral ischemia; Caspase 3; HSP27; Bcl-xl; Fluoro-jade B
Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperLithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus
Keywords: Fluoro-Jade B; lithium pilocarpine; status epilepticus; immature brain; CA; cornu ammonis; DG; dentate gyrus; EEG; electroencephalogram; P; post natal day; Str Pyr; stratum pyramidale;
RelA/p65-serine 536 nuclear factor-kappa B phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus
Keywords: NF-κB; phosphorylation; status epilepticus; neuronal damage; neuronal survival; FJB; fluoro-jade B; IκB; inhibitor of NF-κB; NeuN; neuronal specific nuclear antigen; NF-κB; nuclear factor-kappa B; PB; phosphate buffer; PBS; phosphate-buffered saline;
Time course of neuronal damage in the hippocampus following lithium-pilocarpine status epilepticus in 12-day-old rats
Keywords: Immature rats; Degenerating cells; Fluoro-Jade B; Interneurons; Pyramidal cells
Toxicity assessment of pramipexole in juvenile rhesus monkeys
Keywords: PPX; pramipexole; DA; dopamine; PD; Parkinson's disease; RLS; restless leg syndrome; NCTR; National Center for Toxicological Research; OTB; operant test battery; DIUF; deionized ultra-filtered; MGSS; Multi-Generation Support System; GFAP; glial fibrillary
Pregnancy inhibits cell proliferation and neuroblast differentiation without neuronal damage in the hippocampal dentate gyrus in C57BL/6N mice
Keywords: Pregnancy; Gestation day; Neurogenesis; NeuN; TUNEL; Fluoro-Jade B; Ki67; Doublecortin
TTC, Fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion
Keywords: Fluoro-Jade B; Infarction; Ischemic stroke; Middle cerebral artery occlusion (MCAO); NeuN; Penumbra
Neurodegeneration and prolonged immediate early gene expression throughout cortical areas of the rat brain following acute administration of dizocilpine
Keywords: Egr-1; FosB; MK-801; neurodegeneration; retrosplenial cortex; somatosensory cortex; A-Cu-Ag; amino-cupric-silver; ENT; entorhinal cortex; FJB; fluoro-jade B; IEGs; immediate early genes; MK801; dizocilpine; NHS; normal horse serum; NMDA-A; N-methy
Neuroprotection achieved in the ischaemic rat cortex with l-kynurenine sulphate
Keywords: Neuroprotection; Kynurenic acid; Kynurenine; Global ischaemia; Fluoro-Jade B
Alcohol exposure on postnatal day 5 induces Purkinje cell loss and evidence of Purkinje cell degradation in lobule I of rat cerebellum
Keywords: Fetal alcohol syndrome; Third trimester; Cell death; Ethanol; Stereology; Fluoro-Jade B;
Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage
Keywords: astrocytes; blood; brain edema; hemispheric enlargement; reactive oxygen species; stroke; Avertin; 2-2-2 tribromoethanol; FJB; Fluoro-Jade B; GFAP; glial fibrillary acidic protein; HO; heme oxygenase; ICH; intracerebral hemorrhage; MPO; myeloperoxidase; N
Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice
Keywords: Fluoro-Jade B; Excitotoxicity; Endocannabinoid; [3H]-kainate autoradiography; Racine seizure scale; GABA
Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: An initial event in neuronal injury induction
Keywords: seizures; pilocarpine; neurotrophin receptors; hippocampus; co-immunoprecipitation; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,Nâ²,Nâ² tetra
Delayed neurodegeneration and early astrogliosis after excitotoxicity to the aged brain
Keywords: Aging; Brain; Neurodegeneration; Fluoro-Jade B; Edema; Astrogliosis; Experimental stroke; Excitotoxicity; Striatum
Neonatal administration of N-acetyl-l-aspartyl-l-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats
Keywords: NAAG; Quantitative morphology; TUNEL test; Fluoro-Jade B; Open field test
CD40L deletion delays neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
Keywords: APC; antigen presenting cells; BSA; bovine serum albumin; DAB; 3,3â²-diaminobenzidine; eNOS; endothelial nitric oxide synthase; FJB; Fluoro-Jade B; EAE; experimental autoimmune encephalomyelitis; HO-1; heme oxygenase-1; ICAM-1; intercellular adhesion mol
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures
Keywords: neuroprotection; neurodegeneration; cerebral ischemia; GLT-1; GLAST; GDNF; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-(1H,4H)-dione; dl-TBOA; dl-threo-beta-benzyloxyaspartate; FJ-B; Fluoro-Jade B; GDN
Gene profiling the response to kainic acid induced seizures
Keywords: Neurotransmitters, modulators, transporters, and receptors; Excitatory amino acids: excitotoxicity; Agt; angiotensinogen; Akt; protein kinase B; Aldr1; aldehyde reductase 1; ANPEP; alanyl aminopeptidase N; ATF4; activating transcription factor 4; Bax; BCl
Degenerative neuronal changes in the rat thalamus induced by status epilepticus at different developmental stages
Keywords: Status epilepticus; Lithium pilocarpine; Thalamus; Developing rats; Fluoro-Jade B;