Keywords: اثرات غذایی; Biorelevant dissolution testing; USP apparatus III (BioDis); USP apparatus IV (flow-through cell); Food effects; Zolpidem; PBPK modeling; Qgut; Deconvolution;
مقالات ISI اثرات غذایی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: اثرات غذایی; albumin; mathematical model; pharmacokinetics; protein binding; organic anion-transporting polypeptide transporters; food effects; hepatic transport; nonlinear pharmacokinetics; clinical pharmacokinetics; ADME; BA; bioavailability; BCS; biopharmaceutica
Keywords: اثرات غذایی; intestinal drug absorption; intestinal secretion; gastrointestinal; oral drug delivery; food effects; lipids; pH; phospholipids;
Keywords: اثرات غذایی; pharmacokinetics; physiologically based pharmacokinetic modeling; absorption; food effects; oral absorption; particle size;
Keywords: اثرات غذایی; Food effects; Nutraceuticals; Vitamins; Excipient emulsions; Delivery systems; Functional foods
Keywords: اثرات غذایی; amifampridine; food effects; pharmacokinetics; 3,4-diaminopyridine; 3,4-DAP; Lambert-Eaton Myasthenic Syndrome;
Keywords: اثرات غذایی; cocrystals; food effects; oral absorption; supersaturation; physicochemical properties; preformulation; solubility; surfactants; mathematical model; poorly water-soluble drugs;
Keywords: اثرات غذایی; intestinal absorption; salt selection; bioequivalence; biopharmaceutics classification system (BCS); in silico modeling; dissolution; food effects; formulation; gastrointestinal transit; oral absorption
Keywords: اثرات غذایی; chemical stability; solubility; degradation products; natural products; mathematical model; NMR spectroscopy; kinetics; particle size; food effects;
Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of ABT-493: A First-In-Human Study
Keywords: اثرات غذایی; clinical pharmacokinetics; bioavailability; cytochrome P450; food effects;
Mechanistic prediction of food effects for Compound A tablet using PBPK model
Keywords: اثرات غذایی; Food effects; PBPK; ACAT; Prediction; Pharmacokinetic;
Interaction of Peptide Transporter 1 With d-Glucose and l-Glutamic Acid; Possible Involvement of Taste Receptors
Keywords: اثرات غذایی; absorption; drug interactions; food effects; peptide transporter; membrane translocation;
Trospium chloride is absorbed from two intestinal “absorption windows” with different permeability in healthy subjects
Keywords: اثرات غذایی; Trospium chloride; Pharmacokinetics; Gastric infusion; Food effects; P-glycoprotein; OCT1;
Bile Salt Micelles and Phospholipid Vesicles Present in Simulated and Human Intestinal Fluids: Structural Analysis by Flow Field-Flow Fractionation/Multiangle Laser Light Scattering
Keywords: اثرات غذایی; drug transport; duodenum; intestinal absorption; intestinal secretion/transport; oral drug delivery; food effects; lipids; particle size; phospholipids;
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Keywords: اثرات غذایی; Preformulation; Food effects; Precipitation inhibitors; Amorphous; Biorelevant media; Bioavailability;
Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions
Keywords: اثرات غذایی; active transport; drug interaction; efflux pumps; food effects; flavonoids; genistein; glyceollin; intestinal absorption; intestinal metabolism; phytoestrogen;
Gastrointestinal Behavior of Weakly Acidic BCS Class II Drugs in Man-Case Study of Diclofenac Potassium
Keywords: اثرات غذایی; oral drug delivery; biopharmaceutics; clinical pharmacokinetics; gastrointestinal; supersaturation; precipitation; disposition; food effects; drug interaction; Biopharmaceutics Classification System (BCS);
Can dosage form-dependent food effects be predicted using biorelevant dissolution tests? Case example extended release nifedipine
Keywords: اثرات غذایی; Biorelevant dissolution testing; USP apparatus III (BioDis); USP apparatus IV (flow through cell); Food effects; Nifedipine; Clinical study; IVIVC; Extended release
Evaluation of the Use of Göttingen Minipigs to Predict Food Effects on the Oral Absorption of Drugs in Humans
Keywords: اثرات غذایی; food interaction; food effects; poorly soluble drugs; minipigs; bioavailability; pharmacokinetics;
Computational Fluid Dynamics Simulation of Hydrodynamics and Stresses in the PhEur/USP Disintegration Tester Under Fed and Fasted Fluid Characteristics
Keywords: اثرات غذایی; in vitro models; solid dosage form; mathematical model; oral drug delivery; food effects; biopharmaceutics; LADME; disintegration testing; computational fluid dynamics; hydrodynamics
In vitro biorelevant models for evaluating modified release mesalamine products to forecast the effect of formulation and meal intake on drug release
Keywords: اثرات غذایی; Biorelevant dissolution testing; USP apparatus III (BioDis); USP apparatus IV (flow through cell); Food effects; Mesalamine (5-ASA); Dose dumping;
Suitability of a Minipig Model in Assessing Clinical Bioperformance of Matrix and Multiparticulate Extended-Release Formulations for a BCS Class III Drug Development Candidate
Keywords: اثرات غذایی; controlled release; preclinical pharmacokinetics; pharmacokinetics; food effects; controlled delivery; formulation; in vitro/in vivo correlations (IVIVC);
Quantitative prediction of formulation-specific food effects and their population variability from in vitro data with the physiologically-based ADAM model: A case study using the BCS/BDDCS Class II drug nifedipine
Keywords: اثرات غذایی; Food effects; Simcyp ADAM model; Mechanistic modelling; In vitro-in vivo extrapolation; Oral formulation; PBPK;
Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine
Keywords: اثرات غذایی; Human intestinal fluids; Mouse; in situ intestinal perfusion; Food effects; Indinavir
Effects of particle size, food, and capsule shell composition on the oral bioavailability of dabrafenib, a BRAF inhibitor, in patients with BRAF mutation-positive tumors
Keywords: اثرات غذایی; dabrafenib; food effects; particle size; bioavailability; HPMC; gelatin; capsules; supersaturation; dissolution; clinical pharmacokinetics
Gastric pH and Gastric Residence Time in Fasted and Fed Conscious Beagle Dogs using the Bravo® pH System
Keywords: اثرات غذایی; gastrointestinal transit; residence time; transit time; food effects; oral absorption; Bravo® capsule; gastrointestinal pH; dog;
A Formulation Strategy for Gamma Secretase Inhibitor ELND006, a BCS Class II Compound: Development of a Nanosuspension Formulation with Improved Oral Bioavailability and Reduced Food Effects in Dogs
Keywords: اثرات غذایی; oral drug delivery; bioavailability; Biopharmaceutics Classification System (BCS); crystallinity; dissolution; food effects; solubility; pharmacokinetics; particle size; gamma secretase inhibitor; Alzheimer's disease;
A Randomized, Quadruple Crossover Single-Blind Study on Immediate Action of Chewed and Unchewed Low-Dose Acetylsalicylic Acid Tablets in Healthy Volunteers
Keywords: اثرات غذایی; absorption; clinical pharmacokinetics; clinical trials; food effects; formulation; gastrointestinal transit; pharmacodynamics; tablet; regulatory science
Drug Supersaturation in Simulated Human Intestinal Fluids Representing Different Nutritional States
Keywords: اثرات غذایی; supersaturation; solubility; gastrointestinal; precipitation; food effects;
Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form
Keywords: اثرات غذایی; Biorelevant dissolution tests; Bio-Dis; Flow-through cell; In vitro–in vivo correlations; Food effects; Diclofenac sodium
Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling
Keywords: اثرات غذایی; Food effects; Dissolution; Prediction; PBPK modeling; Celecoxib
Scintigraphic Study to Investigate the Effect of Food on a HPMC Modified Release Formulation of UK-294,315
Keywords: اثرات غذایی; UK-294,315; scintigraphy; food effects; modified release; pharmacokinetics;
Factors Influencing the Gastric Residence of Dosage Forms in Dogs
Keywords: اثرات غذایی; preclinical pharmacology; gastrointestinal transit; bioavailability; food effects; oral absorption;
Relative bioavailability of griseofulvin lyophilized dry emulsion tablet vs. immediate release tablet: A single-dose, randomized, open-label, six-period, crossover study in healthy adult volunteers in the fasted and fed states
Keywords: اثرات غذایی; Griseofulvin; Lyophilized dry emulsion tablets; In vivo absorption; Pharmacokinetics; Bioavailability; Food effects
Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption
Keywords: اثرات غذایی; Absorption; BCS; BDDCS; Disposition; Elimination; Food effects; Interplay; Transporter
Effect of Food Intake on the Oral Absorption of Poorly Water-Soluble Drugs: In Vitro Assessment of Drug Dissolution and Permeation Assay System
Keywords: اثرات غذایی; absorption; biopharmaceutics classification system (BCS); Caco-2 cells; dissolution; food effects; in vitro/in vivo correlations (IVIVC); permeability; solubility;