Keywords: Formononetin; Daidzein; Solubility; Intermolecular interaction; Thermodynamic model; COSMO-RS;
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Keywords: Astragali radix; Astragaloside IV; Calycosin; Formononetin; Drug metabolizing enzymes; Efflux transporters;
Keywords: Propolis; Analgesics; Flavonoids; Formononetin; Inflammation.; ASA; acetylsalicylic acid; CI 95%; 95% confidence interval; Dexa; dexamethasone; ED50; median effective dose; FOR; formononetin; HERP; hydroalcoholic extract of red propolis; IL; interleukin;
Keywords: Antimycobacterial; Formononetin; Pharmacophore; Structure; Activity;
Neuroprotective effect of formononetin against TBI in rats via suppressing inflammatory reaction in cortical neurons
Keywords: Formononetin; Traumatic brain injury; Interleukin-10; Inflammation;
Formononetin inhibits neuroinflammation and increases estrogen receptor beta (ERβ) protein expression in BV2 microglia
Keywords: Formononetin; Neuroinflammation; NF-κB; ERβ;
Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells
Keywords: Formononetin; Astragalus membranaceus; Ovarian cancer; Mechanism;
Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model
Keywords: Formononetin; STAT; ROS; Multiple myeloma;
Formononetin attenuated allergic diseases through inhibition of epithelial-derived cytokines by regulating E-cadherin
Keywords: Formononetin; E-cadherin; IL-33; TSLP; Allergic disease;
Research articleFormononetin attenuates Aβ25-35-induced cytotoxicity in HT22 cells via PI3K/Akt signaling and non-amyloidogenic cleavage of APP
Keywords: amyloid β; Aβ; Alzheimer's disease; AD; estrogen receptor α; ERα; formononetin; Form; soluble amyloid precursor protein α; sAPPα; Alzheimer's disease; β-amyloid; Formononetin; APP; ERα; PI3K/Akt;
Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3Â cells via MAPK/Wnt signaling pathways
Keywords: Formononetin; Dithiocarbamate; Growth; Migration;
Quantification of isoflavonoids and triterpene saponins in Astragali Radix, the root of Astragalus membranaceus, via reverse-phase high-performance liquid chromatography coupled with integrated pulsed amperometric detection
Keywords: Astragali radix; Hwanggi-gyeji-omul-tang; Calycosin; Formononetin; Astragalosides; Integrated amperometric detection; Direct method;
Characterization and cytotoxicity of PLGA nanoparticles loaded with formononetin cyclodextrin complex
Keywords: Formononetin; 2-Hydroxypropyl-β-cyclodextrin; Inclusion complex; PLGA nanoparticles; Cytotoxicity;
Isoflavone formononetin from red propolis acts as a fungicide against Candida sp
Keywords: Bioassay-guided fractionation; Red propolis; Isoflavone; Formononetin; Candida
Antiproliferative effects of formononetin on human colorectal cancer via suppressing cell growth in vitro and in vivo
Keywords: Formononetin; Colorectal cancer; Signal pathway; Proliferation;
Molecular structure, spectral investigation (1H NMR, 13C NMR, UV–Visible, FT-IR, FT-Raman), NBO, intramolecular hydrogen bonding, chemical reactivity and first hyperpolarizability analysis of formononetin [7-hydroxy-3(4-methoxyphenyl)chromone]: A quantum
Keywords: Formononetin; FT-IR; FT-Raman; Hydrogen bonding; UV–Vis spectra; Reactivity descriptors
Two activators of in vitro fertilization in mice from licorice
Keywords: Sperm; Licorice; Glycyrrhizin; Insemination; Assisted reproductive technology (ART); Flavonoid; Polyphenol; Isoliquiritigenin; Formononetin;
Formononetin mediates neuroprotection against cerebral ischemia/reperfusion in rats via downregulation of the Bax/Bcl-2 ratio and upregulation PI3K/Akt signaling pathway
Keywords: Formononetin; Cerebral ischemia/reperfusion; ER-α; PI3K/Akt pathway; Bcl-2; Bax
Formononetin protects TBI rats against neurological lesions and the underlying mechanism
Keywords: Formononetin; Traumatic brain injury; Rat; Inflammation; Oxidative stress; Neuroprotection;
Alkylation of guanine by formononetin nitrogen mustard derivatives: A DFT study
Keywords: DNA alkylation; DFT; Aziridinium ion; MEP; MHP; Formononetin;
Isoflavone content and estrogenic activity of different batches of red clover (Trifolium pratense L.) extracts: An in vitro study in MCF-7 cells
Keywords: Biochanin A (PubChem CID: 5280373); Daidzein (PubChem CID: 5281708); Genistein (PubChem CID: 5280961); Formononetin (PubChem CID: 5280378); Estradiol (PubChem CID: 5757); Tamoxifen (PubChem CID: 2733526); 4-Hydroxytamoxifen (PubChem CID: 449459); Red clov
Antitumoural activity of Brazilian red propolis fraction enriched with xanthochymol and formononetin: An in vitro and in vivo study
Keywords: Brazilian red propolis; BRP-IV fraction; Xanthochymol; Formononetin; Murine melanoma model; Haematological cancer;
Cardiovascular pharmacologyAntihypertensive effect of formononetin through regulating the expressions of eNOS, 5-HT2A/1B receptors and α1-adrenoceptors in spontaneously rat arteries
Keywords: Formononetin; Antihypertension; α1-adrenoceptor; 5-HT2A/1B receptor; Endothelial nitric oxide synthase;
Anti-amyloidogenic effects of soybean isoflavones in vitro: Fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils
Keywords: Aβ; amyloid β-protein; AFM; atomic force microscopy; AU; arbitrary unit; CD; circular dichroism; CSF; cerebrospinal fluid; Dai; daidzein; DTT; dithiothreitol; EM; electron microscopy; Equ; (±)-Equol; EM; emission; EX; excitation; fAβs; Aβ fibrils; Fo
Synthesis and antitumor activity of formononetin nitrogen mustard derivatives
Keywords: Formononetin; Nitrogen mustard; Synthesis; Cytotoxicity; Cell cycle; Apoptosis;
PAMPA permeability, plasma protein binding, blood partition, pharmacokinetics and metabolism of formononetin, a methoxylated isoflavone
Keywords: Formononetin; Isoflavone; Permeability; Protein binding; RBC uptake; Pharmacokinetics;
Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways
Keywords: Formononetin; Wound repair; Early growth response factor (Egr)-1; Extracellular signal-regulated kinase (ERK) 1/2; p38 mitogen-activated protein kinase
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Keywords: Incubation pretreatment; Endogenous enzyme; Negative-pressure cavitation extraction; Calycosin; Formononetin; Radix Astragali
Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin
Keywords: Enrichment; Calycosin; Formononetin; Radix Astragali residues; Antioxidant activity; Macroporous resins
Method development and validation for isoflavones quantification in coffee
Keywords: Isoflavones; Daidzein; Genistein; Formononetin; coffee; Hydrolysis; HPLC; Diode-array
Isoflavones isolated from red clover (Trifolium pratense) inhibit smooth muscle contraction of the isolated rat prostate gland
Keywords: Smooth muscle contractility; Genistein; Formononetin; Biochanin A; Chemical fractionation
Quantitative determination of formononetin and its metabolite in rat plasma after intravenous bolus administration by HPLC coupled with tandem mass spectrometry
Keywords: Formononetin; Daidzein; Rat plasma; Validation; LC–MS/MS; Pharmacokinetics
Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways
Keywords: Formononetin; Nitric oxide; Vasorelaxation; BKCa and KATP channels
Biphasic positive effect of formononetin on metabolic activity of human normal and osteoarthritic subchondral osteoblasts
Keywords: Formononetin; Osteoarthritis; Subchondral osteoblasts; Osteogenic; Inflammatory mediators
Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover)
Keywords: Formononetin; Isoflavone; Estrogenic effect; Antioxidant effect; Trifolium pratense (red clover)
Formononetin promotes early fracture healing through stimulating angiogenesis by up-regulating VEGFR-2/Flk-1 in a rat fracture model
Keywords: Formononetin; VEGF; VEGF receptor; Osteogenesis; Bone healing
Tissue distribution of isoflavones in ewes after consumption of red clover silage
Keywords: Isoflavones; Formononetin; Biochanin A; Daidzein; Equol; Red clover; Ewe; Tissue distribution; Bioavailability
Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor
Keywords: Isoflavones; Biochanin A; Formononetin; AhR; Aryl hydrocarbon receptor; Indole compounds
Human serum albumin interaction with formononetin studied using fluorescence anisotropy, FT-IR spectroscopy, and molecular modeling methods
Keywords: Formononetin; Human serum albumin; Fluorescence anisotropy; FT-IR spectroscopy
Analysis of formononetin from black cohosh (Actaea racemosa)
Keywords: Formononetin; Black cohosh; Actaea racemosa; Cimicifuga racemosa; TLC; HPLC-PDA; LC-MS; Analysis
Identification and determination of major flavonoids in rat serum by HPLC-UV and HPLC-MS methods following oral administration of Dalbergiaodorifera extract
Keywords: Dalbergia odorifera; Flavonoids; (3R)-4â²-methoxy-2â²,3,7-trihydroxy-isoflavanone; Vestitone; Formononetin; Sativanone;
Influence of a flavonoid (formononetin) on mycorrhizal activity and potato crop productivity in the highlands of Peru
Keywords: Aluminum (Al); Arbuscular mycorrhizal fungi (AMF); Biofertilizers; Formononetin; Glomus spp.; Gigaspora spp.; Isoflavonoid; Phosphorus (P); Solanum tuberosum L;
Amplified fragment length polymorphism and metabolomic profiles of hairy roots of Psoralea corylifolia L.
Keywords: Psoralea corylifolia; Papilionaceae; Hairy roots; Metabolomics; AFLP; Isoflavonoids; Formononetin;