Keywords: FP، قطبش فلورسانس; HIg, human immunoglobulin; SEM, scanning electron microscope; FT-IR, Fourier transform infrared; FP, fluorescence polarization; AIR, attenuated total reflection; H, heavy chains; L, light chains; Fab, fragment of antigen binding; Fc, crystallizable fragme
مقالات ISI FP، قطبش فلورسانس (ترجمه نشده)
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Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction
Keywords: FP، قطبش فلورسانس; AlphaScreen, amplified luminescent proximity homogeneous assay screen; BSA, bovine serum albumin; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; FP, fluorescence polarization; GB1, protein G B1 domain; HEPES, 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane
Selective inhibitors of Bcl-2 and Bcl-xL: Balancing antitumor activity with on-target toxicity
Keywords: FP، قطبش فلورسانس; FP, fluorescence polarization; SPR, surface plasmon resonance; FRET, fluorescence resonance energy transfer; LPA, luminescence proximity assayApoptosis; Protein–protein interactions; Bcl-2 family proteins; Selectivity
Helicase associated 2 domain is essential for helicase activity of RNA helicase A
Keywords: FP، قطبش فلورسانس; ADAR, adenosine deaminase acting on RNA; dsRNA, double-stranded RNA; dsDNA, double-stranded DNA; dsRBD, double-stranded RNA binding domain; FTSC, fluorescein-5-thiosemicarbazide; FP, fluorescence polarization; GST, Glutathione S-transferase; HA2, helicase
Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ
Keywords: FP، قطبش فلورسانس; PFCs, perfluorinated compounds; hPPARγ, human peroxisome proliferator-activated receptor γ; PFCAs, perfluorinated carboxylic acids; PFSAs, perfluorinated sulfonic acids; FTOHs, fluorotelomer alcohols; FP, fluorescence polarization; CD, circular dichroism;
Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma
Keywords: FP، قطبش فلورسانس; BHR, bronchial hyperresponsiveness; CD, Crohn's disease; FBAT, family based association test; FEV1, forced expiratory volume in 1 second; FP, fluorescence polarization; IFN, interferon; IgE, immunoglobulin E; IL, interleukin; indel, insertion–deletion pol
Molecular probes for the A2A adenosine receptor based on a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine scaffold
Keywords: FP، قطبش فلورسانس; AR, adenosine receptor; BODIPY, 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; CHO, chinese hamster ovary; CNS, central nervous system; DMF, N,N-dimethylformamide; EDC, N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide; FP, fluorescence polarization; HEK, human
Feasibility of gymnodimine and 13-desmethyl C spirolide detection by fluorescence polarization using a receptor-based assay in shellfish matrixes
Keywords: FP، قطبش فلورسانس; nAChR, nicotinic acetylcholine receptor; BSA, bovine serum albumin; α-BTX, α-bungarotoxin; FP, fluorescence polarization; GYM, gymnodimine; PBS, phosphate buffered saline; SPX, spirolideCyclic imines; Gymnodimine; Spirolide; Fluorescence polarization; Nic
Identification and characterization of a novel estrogenic ligand actinopolymorphol A
Keywords: FP، قطبش فلورسانس; BRET, bioluminescence resonance energy transfer; ERα, estrogen receptor α; ERβ, estrogen receptor β; LBD, ligand binding domain; FP, Fluorescence Polarization; HTS, high throughput screening; NPE, natural product extract; EDC, endocrine disrupting compoun
Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain
Keywords: FP، قطبش فلورسانس; IDA, iminodiacetate; F-GpYEEI, fluorescein-labeled GpYEEI; FP, fluorescence polarization; CD, circular dichroismPhosphopeptides; Metal chelation; Iminodiacetate group; SH2 domain; UV titration; Fluorescence polarization; Circular dichroism
Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150
Keywords: FP، قطبش فلورسانس; RNAP II, RNA polymerase II; pCTD, phosphorylated C-terminal domain; PDB, Protein Data Bank; SAD, single-wavelength anomalous dispersion; SeMet, selenomethionine; GST, glutathione S-transferase; FP, fluorescence polarization; MALS, multiangle light scatter
Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase
Keywords: FP، قطبش فلورسانس; FP, fluorescence polarization; Galf, galactofuranose; UDP, uridine 5'-diphosphate; UDP-Galp, UDP-galactopyranose; UGM, UDP-galactopyranose mutase; UDP-Glc, UDP-glucose; FAD, flavin adenine dinucleotide; STD, saturation transfer difference; UDP-Glcp, UDP-g
Modulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1α
Keywords: FP، قطبش فلورسانس; CBP, cAMP-response element-binding protein; CK2, casein kinase 2; C-TAD, C-terminal transactivation domain; FIH-1, factor inhibiting HIF-1α; FP, fluorescence polarization; HIF, hypoxia-inducible factor; VHL, von Hippel-Lindau proteinHypoxia-inducible fact
The high throughput screening of neuropeptide FF2 receptor ligands from Korean herbal plant extracts
Keywords: FP، قطبش فلورسانس; CRE, cAMP response element; ESI-MS, electrospray interface-mass spectrometry; FP, fluorescence polarization; GPCRs, G-protein coupled receptors; NPFF, neuropeptide FF; DMe NPFF, D-Tyr-Leu-(N-methyl)Phe-Gln-Pro-Gln-Arg-Phe-NH2; HTS, high throughput screeni
Recognition of a CXCR4 Sulfotyrosine by the Chemokine Stromal Cell-derived Factor-1α (SDF-1α/CXCL12)
Keywords: FP، قطبش فلورسانس; NOE, nuclear Overhauser effect; NOESY, NOE spectroscopy; HSQC, heteronuclear single quantum coherence; FP, fluorescence polarization; GAG, glycosaminoglycan; TOCSY, total correlation spectroscopyGPCR; tyrosine sulfonation; NMR; post-translational modifica
Structure of the SCAN Domain from the Tumor Suppressor protein MZF1
Keywords: FP، قطبش فلورسانس; MZF, myeloid zinc finger; GST, glutathione-S-transferase; ZFP, zinc finger protein; HSQC, heteronuclear single quantum coherence; FP, fluorescence polarization; NOE, nuclear Overhauser effect; NOESY, NOE spectroscopyNMR; fluorescence polarization; SCAN do
Critical factors in the development of fluorescence polarization-based peptide binding assays: An equilibrium study monitoring specific peptide binding to soluble HLA-A⁎0201
Keywords: FP، قطبش فلورسانس; 1HLA, human leukocyte antigen; sHLA, soluble HLA; MHC, major histocompatibility complex; β2m, β-2 microglobulin; TAP, transporter associated with antigen processing; FP, fluorescence polarization; mP, milli-polarization; FITC, fluorescein isothiocyanate;