RhoA co-ordinates with heterotrimeric G proteins to regulate efficacy
Keywords: پروتئین G; G proteins; GTPases; GPCRs; Phosphatidic acid; Phospholipase D; Phospholipase C-β; RhoA;
مقالات ISI پروتئین G (ترجمه نشده)
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Multifaceted cardiac signal transduction mediated by G protein-coupled receptors: Potential target sites where an unambiguous attention is needed for exploring new drugs for cardiovascular disorders
Keywords: پروتئین G; GPCR; G proteins; CaM kinase II; RGS2; β-arrestin; EGFR; β-arrestin-biased ligands
Millimolar Mn2+ influences agonist binding to 5-HT1A receptors by inhibiting guanosine nucleotide binding to receptor-coupled G-proteins
Keywords: پروتئین G; 5-HT1A receptor; Manganese; Hippocampus; Cortex; G proteins; Guanosine nucleotides;
Competitive interaction of 5-HT1A receptors with G-protein subtypes in CHO cells demonstrated by RNA interference
Keywords: پروتئین G; siRNA; 5-HT1A receptor; G proteins; Agonist trafficking
Through scaffolding and catalytic actions nucleoside diphosphate kinase B differentially regulates basal and β-adrenoceptor-stimulated cAMP synthesis
Keywords: پروتئین G; NDPK; β-adrenoceptors; G proteins; cAMP; Histidine phosphorylation;
Contribution of G inhibitory protein alpha subunits in paradoxical hyperalgesia elicited by exceedingly low doses of morphine in mice
Keywords: پروتئین G; Antisense oligodeoxynucleotides; G proteins; Hot plate test; Hyperalgesia; Morphine; Immunoprecipitation;
Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20Â days after morphine withdrawal
Keywords: پروتئین G; AC; adenylyl cyclase; β-AR; β-adrenergic receptor; DADLE; [2-d-alanine, 5-d-leucine]enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DAMGO; [2-d-alanine, 4-N-methylphenylalanine, 5-glycinol]enkephalin = Tyr-d-Ala-Gly-N-methyl-Phe-Gly-ol; DOR; δ-opioid recepto
Elucidating biological risk factors in suicide: Role of protein kinase A
Keywords: پروتئین G; BDNF, brain-derived neurotrophic factor; CREB, cyclic adenosine monophosphate response element binding protein; PFC, prefrontal cortex; PKA, Protein kinase AAnimal models; Depression; G proteins; Human postmortem brain; Protein kinase A; Suicide
Fluorescence spectroscopy studies of HEK293 cells expressing DOR-Gi1α fusion protein; the effect of cholesterol depletion
Keywords: پروتئین G; β-CDX; β-cyclodextrin; DADLE; D-Ala2-D-Leu5 enkephalin; DMEM; Dulbecco's modified Eagle's medium; DOR; δ-opioid receptor; DOR-Gi1α cells; HEK293 cells stably expressing DOR-Gi1α (Cys351-Ile351) fusion protein; DPH; 1,6-diphenyl-1,3,5-hexatriene; DR
Valproate attenuates the development of morphine antinociceptive tolerance
Keywords: پروتئین G; MOR; mu opioid receptor; G proteins; heterotrimeric guanine nucleotide-binding proteins; GSK3β; glycogen synthase kinase 3β; GABA; γ-aminobutyric acid; Morphine tolerance; Mood stabilizer; Opioid; Glycogen synthase kinase;
Europium-labeled GTP as a general nonradioactive substitute for [35S]GTPγS in high-throughput G protein studies
Keywords: پروتئین G; G proteins; Eu-GTP; [35S]GTPγS; High throughput; Time-resolved fluorescence; G protein-coupled receptors;
Activation of STAT3 by specific Gα subunits and multiple Gβγ dimers
Keywords: پروتئین G; G proteins; G14; G16; Gβγ; STAT3
Gβγ is a negative regulator of AP-1 mediated transcription
Keywords: پروتئین G; Fos; G proteins; Transcription; Protein fragment complementation; Signalling
The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond
Keywords: پروتئین G; CNS; Central nervous system; COMT; catechol-o-methyl transferase; CYP; Cytochrome P450; DA; Dopamine; ED; Electrochemical detector; GABA; γ-Aminobutyric acid; G proteins; Guanine nucleotide binding proteins; GTP; Guanine triphosphate; HPLC; High performa
Enhancement of agonist binding to 5-HT1A receptors in rat brain membranes by millimolar Mn2+
Keywords: پروتئین G; 5-HT1A receptor; Manganese; Hippocampus; Cortex; G proteins;
Activators of G proteins inhibit GSK-3β and stabilize β-Catenin in Xenopus oocytes
Keywords: پروتئین G; GSK-3β; β-Catenin; G proteins; Wnt signaling;
Effect of olfactory bulbectomy on adenylyl cyclase activity in the limbic system
Keywords: پروتئین G; Adenylyl cyclase; Limbic system; Bulbectomy olfactory; G proteins
PI3Kγ activation by CXCL12 regulates tumor cell adhesion and invasion
Keywords: پروتئین G; CXCR4; CXCL12; Chemokines; Chemokine receptors; Adhesion; Invasion; PI3Kγ; G proteins
Sartan–AT1 receptor interactions: In vitro evidence for insurmountable antagonism and inverse agonism
Keywords: پروتئین G; Sartans; AT1 receptors; Insurmountable antagonism; Inverse agonism; G proteins; Cardiomyocytes
G protein-coupled receptors stimulation and the control of cell migration
Keywords: پروتئین G; G protein-coupled receptors; Migration; Actin remodeling; G proteins; Arrestin
In situ molecular level studies on membrane related peptides and proteins in real time using sum frequency generation vibrational spectroscopy
Keywords: پروتئین G; Sum frequency generation; SFG; Cell membrane; Antimicrobial peptide; Membrane protein; Lipid bilayer; Melittin; G proteins; Alamethicin; Tachyplesin I
G protein βγ dimer expression in cardiomyocytes: Developmental acquisition of Gβ3
Keywords: پروتئین G; G proteins; Cardiomyocytes; Development; Caveolae;
The specific activation of TRPC4 by Gi protein subtype
Keywords: پروتئین G; Transient receptor potential channel; Nonselective cation channel; TRPC4; TRPC5; TRPC6; TRPV6; G proteins
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex
Keywords: پروتئین G; Signal transduction; G proteins; Arf; GAP; Photoreceptor;
Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells
Keywords: پروتئین G; Gonadotropin receptors; G protein-coupled receptors; Src family kinases; Fyn; Arrestins; G proteins
Late-stage alterations in myofibrillar contractile function in a transgenic mouse model of dilated cardiomyopathy (Tgαq*44)
Keywords: پروتئین G; G proteins; Cardiac function; Heart failure; Transgenic mouse; Dilated cardiomyopathy; Protein kinase A (PKA); Protein kinase C; Troponin I; Phosphorylation;
Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling
Keywords: پروتئین G; Trafficking; G proteins; PWR spectroscopy; Functional selectivity
Membrane interactions of G proteins and other related proteins
Keywords: پروتئین G; G proteins; Ras proteins; GRK; Protein–lipid interaction; Posttranslational lipid modifications; Membrane lipid structure; Cell signaling
Differential regulation of cyclic AMP synthesis by estrogen in MCF7 cells
Keywords: پروتئین G; Estrogen receptor; Chronic and short-term estrogen treatment; cAMP; G proteins
Effects of local anesthetics on opioid inhibition of calcium current in rat dorsal root ganglion neurons
Keywords: پروتئین G; Local anesthetics; Opioids; G proteins; DRG neurons; Sensory neurons; Calcium channels
Constitutive activity and inverse agonism at the α1adrenoceptors
Keywords: پروتئین G; GPCR, G protein-coupled receptor; AR, adrenoceptor; CAM, constitutively active mutant; MD, molecular dynamicsAdrenoceptors; G protein-coupled receptors; G proteins; Constitutive activity; Inverse agonism; Molecular dynamics
Multiple sensory G proteins in the olfactory, gustatory and nociceptive neurons modulate longevity in Caenorhabditis elegans
Keywords: پروتئین G; C. elegans; G proteins; Sensory signaling; Longevity; Aging; Insulin/IGF-1 signaling; Dauer development
Involvement of Gq/11 in both integrin signal-dependent and -independent pathways regulating endothelin-induced neural progenitor proliferation
Keywords: پروتئین G; Neural progenitor cells; Endothelin; G proteins; Proliferation; Protein kinase C; Extracellular matrix; Paxillin;
The pga1 gene of Penicillium chrysogenum NRRL 1951 encodes a heterotrimeric G protein alpha subunit that controls growth and development
Keywords: پروتئین G; G proteins; Growth and development; Penicillium chrysogenum; Conidiogenesis; pga1 Gene expression
Regulation of G proteins by human 5-HT1a receptor TM3/i2 and TM5/i3 loop peptides
Keywords: پروتئین G; Serotonin; 5HT1a receptor; G proteins; Synthetic peptides; Cyclic AMP; [35S]γ-S-GTP
Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation
Keywords: پروتئین G; Dopamine D3 receptor; Antipsychotics; Schizophrenia; ERK 1/2; G proteins
Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function
Keywords: پروتئین G; G proteins; RGS5; Phosphorylation; Protein kinase C; GTPase-activating proteins
R4 RGS proteins: Regulation of G-protein signaling and beyond
Keywords: پروتئین G; G proteins; Signal transduction; RGS proteins3iL, 3rd intracellular loop; AC, adenylyl cyclase; AMF, aluminum magnesium fluoride; AR, adrenergic receptor; EGFR, epidermal growth factor receptor; GAP, GTPase accelerating protein; GIRK channel, G-protein re
Hypothesis: VPAC G protein-coupled receptors for vasoactive intestinal peptide constitute a dynamic system for signaling T cells from plasma membrane and nuclear membrane complexes
Keywords: پروتئین G; VIP; vasoactive intestinal peptide; GPCR; G protein-coupled receptor; VPAC1; type 1 VIP receptor; VPAC2; type 2 VIP receptor; T cell; T lymphocyte; LPA; lysophosphatidic acid; S1P; sphingosine 1-phosphate; LPA1; type 1 LPA receptor; iNOS; inducible nitric
Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins
Keywords: پروتئین G; Receptor–receptor interactions; Adenosine A1 receptor; Dopamine D1 receptor; G proteins; Adenylate cyclase; Sf9 cell line
Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon
Keywords: پروتئین G; serotonin; hypothalamus; prolactin; corticosterone; G proteins; rats; ANOVA; analysis of variance; (â)DOI; (â)-1-(2,5 dimethoxy-4-iodophenyl)-2-amino-propane HCl; HPA; hypothalamic-pituitary-adrenal axis; IOD; integrated optical density; PVN; hypo
Dexamethasone mimics the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia and compensates for morphine induced changes in G proteins gene expression
Keywords: پروتئین G; Morphine tolerance; Dexamethasone; G proteins; Gene expression; Rat
Probing rhodopsin–transducin interaction using Drosophila Rh1–bovine rhodopsin chimeras
Keywords: پروتئین G; Rhodopsin; Drosophila rhodopsin Rh1; Transducin; GPCR; G proteins; Phototransduction
Transducin subunit stoichiometry and cellular distribution in rod outer segments
Keywords: پروتئین G; Transducin; G Proteins; WD40-repeat proteins; Visual transduction;
Signaling pathways mediating chemotaxis in the social amoeba, Dictyostelium discoideum
Keywords: پروتئین G; Dictyostelium discoideum; Phosphoinositides; PI3K; PTEN; Chemotaxis; Cell migration; G proteins; G protein-coupled receptor; cAMP
Functional domains of the subtype 1 neurotensin receptor (NTS1)
Keywords: پروتئین G; NTS1; GPCR; G proteins; Agonist; Antagonist; Constitutive activity
Role of G proteins and ERK activation in hemin-induced erythroid differentiation of K562 cells
Keywords: پروتئین G; Erythroid differentiation; Hemin; G proteins; ERK1/2 phosphorylation; K562
Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5â²-O-(γ-thiotriphosphate) binding in rat striatal membranes
Keywords: پروتئین G; CHO; Chinese hamster ovary; EC50; the concentration eliciting the half-maximal stimulation; %Emax; the percent maximal increase above the basal binding; G protein; guanine nucleotide-binding regulatory protein; GTPγS; guanosine 5â²-O-(γ-thiotriphosphat
Regulation of cardiomyocyte signaling by RGS proteins: Differential selectivity towards G proteins and susceptibility to regulation
Keywords: پروتئین G; G proteins; RGS proteins; Cardiomyocytes; Hypertrophy; Signal transduction
Molecular pathways underlying the modulation of T-type calcium channels by neurotransmitters and hormones
Keywords: پروتئین G; T-type calcium channels; α1G; α1H; α1I; G proteins; Protein kinase; PKA; PKC; PKG; Calmoduline kinase II; Facilitation