دانلود مقالات ISI درباره GA، geldanamycin + ترجمه فارسی

غربالگری پروتئین شوک حرارتی مبتنی بر میکروارگانیسم

Microarray-based screening of heat shock protein inhibitors

Keywords: GA، geldanamycin; 17-AAG, 17-N-allylamino-17-demethoxygeldanamycin; BSA, bovine serum albumin; Cy3, carbocyanin 3; DMSO, dimethylsulfoxid; FITC, fluoresceinisothiocyanat; GA, geldanamycin; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HSP, heat shock protein;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Specificity in the actions of the UBR1 ubiquitin ligase in the degradation of nuclear receptors

Keywords: GA، geldanamycin; Ubiquitin ligase; Quality control; Degradation; Molecular chaperone; Hsp90; UBR1AR, androgen receptor; CHIP, C-terminal Hsp interacting protein; DMSO, dimethylsulfoxide; ER, estrogen receptor; GA, geldanamycin; GR, glucocorticoid receptor; HA, hemagglutin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines

Keywords: GA، geldanamycin; Actin remodeling; Cell matrix; Cell adhesion; Hypoxia; Radiation; Stress fibersCGM, complete growth medium; FAK, focal adhesion kinase; Erk, extracellular signal regulated kinase; FBS, fetal bovine serum; GA, geldanamycin; IR, ionizing radiation; Hsp, hea

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes

Keywords: GA، geldanamycin; CHC, Clathrin heavy chain; EGFR, Epidermal growth factor receptor; EEA1, Early endosome antigen 1; ESCRT, Endosomal sorting complex required for transport; GA, Geldanamycin; Hsp90, Heat shock protein 90; LAMP1, Lysosomal-associated membrane protein 1; PAE

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90

Keywords: GA، geldanamycin; 17-AAG, 17-allylamino-17-demethoxygeldanamycin; 17-DMAG, 17-dimethylaminoethylamino-17-demethoxygeldanamycin; DMF, dimethylformamide; DMSO, dimethylsulfoxide; GA, geldanamycin; HIF, hypoxia-inducable factor; HRMS, high resolution molecular ion determinati

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells

Keywords: GA، geldanamycin; 17AAG, 17-allylamino-17-demethoxy-geldanamycin; CFTR, cystic fibrosis transmembrane conductance regulator; DMSO, dimethyl sulfoxide; ERK, extracellular signal-regulated kinase; GA, geldanamycin; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK-3, glyc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT

Keywords: GA، geldanamycin; hTERT, human telomerase reverse transcriptase; Hsp90, heat shock protein 90; GA, geldanamycin; TRAP, telomeric repeat amplification protocol; LMB, leptomycin B; NES, nuclear export signal; ITAS, internal telomerase assay standard; RT-PCR, reverse transcri

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Functional characterization of orchardgrass endoplasmic reticulum-resident Hsp90 (DgHsp90) as a chaperone and an ATPase

Keywords: GA، geldanamycin; ATPase; Chaperone; Endoplasmic reticulum; Heat shock protein 90; Orchardgrass (Dactylis glomerata L.); ThermotoleranceBiP, 78 kDa binding protein; CS, citrate synthase; ER, endoplasmic reticulum; GA, geldanamycin; Grp, glucose-regulated protein; GST, glut

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Indirect participation of Hsp90 in the regulation of the cyclin E turnover

Keywords: GA، geldanamycin; Hsp90, heat shock protein 90; GA, geldanamycin; MG132, proteasome inhibitor (N-benzoyloxy-carbonyl (Z)-Leu-Leu-leucinal); CHX, cycloheximide; Cdk, cyclin-dependent kinase; PPIase, peptidylprolyl isomerase; PMSF, phenyl methyl sulfonyl fluoride; PBS, phosp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Role of oxidative stress in geldanamycin-induced cytotoxicity and disruption of Hsp90 signaling complex

Keywords: GA، geldanamycin; DMSO, dimethyl sulfoxide; Hsp90, heat shock protein 90; GA, geldanamycin; MEN, menadione; ROS, reactive oxygen species; NAC, N-acetylcysteine; MnTBAP, 4-[Mn(III) tetrakis-(4-benzoic acid)porphyrin chloride]; MTT, 3-(4,5-methylthiazol-2-yl)-2,5-diphenyltet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor β-activated kinase 1 (TAK1) in interleukin-1β-induced cell signaling

Keywords: GA، geldanamycin; Hsp90, heat shock protein 90; TAK1, transforming growth factor β-activated kinase 1; IL-1β, interleukin-1β; TNFα, tumor necrosis factorα; GA, geldanamycin; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor-κB; COX-2, cyclooxygenase-2; JNK, c-J

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Heat shock protein 90 regulates stabilization rather than activation of soluble guanylate cyclase

Keywords: GA، geldanamycin; cGMP, cyclic GMP; eNOS, endothelial NO synthase; GA, geldanamycin; hsp90, heat shock protein 90; NO, nitric oxide; PPAECs, porcine pulmonary artery endothelial cells; RD, radicicol; sGC, soluble guanylate cyclase; SMCs, smooth muscle cellsSoluble guanylat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Pharmacological induction of the heat shock response improves myelination in a neuropathic model

Keywords: GA، geldanamycin; PMP22, peripheral myelin protein 22; Schwann cell, SC; Wt, wild type; HSP, heat shock protein; DMSO, dimethylsulfoxide; GA, geldanamycin; HS, heat shock; CMT1A, Charcot–Marie–Tooth disease type 1A; P, postnatal; DRG, dorsal root ganglion; HSF1, heat shock

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Heat Shock Protein 90 Regulates Development in Dictyostelium discoideum

Keywords: GA، geldanamycin; Hsp90, heat shock protein 90; GA, geldanamycin; TRAP1, tumor-necrosis-factor-receptor-associated protein 1; Grp94, glucose-regulated protein 94; GFP, green fluorescent protein; 2D GE, two-dimensional gel electrophoresis; PDB, Protein Data Bank; PKBR1, pro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Geldanamycin induces G2 arrest in U87MG glioblastoma cells through downregulation of Cdc2 and cyclin B1

Keywords: GA، geldanamycin; Hsp90, heat shock protein 90; GA, geldanamycin; CHX, cycloheximide; DMSO, dimethyl sulfoxide; DMEM, Dulbecco's modified Eagle medium; PI, propidium iodide; FACS, fluorescence-activated cell sorter; Tyr 15, tyrosine 15; Thr 14, threonine 14Cell cycle arres

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Mechanistic Studies on Hsp90 Inhibition by Ansamycin Derivatives

Keywords: GA، geldanamycin; GA, geldanamycin; BDGA, 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-geldanamycin; 17-AAG, 17-allylamino-17-demethoxygeldanamycin; DMAG, 17-dimethyl-aminoethyl-17-demethoxygeldanamycin; ITC, isothermal calorimetry; TCEP, tris-(2-carboxyethyl) phosphineITC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Cystein cathepsin and Hsp90 activities determine the balance between apoptotic and necrotic cell death pathways in caspase-compromised U937 cells

Keywords: GA، geldanamycin; AIF, apoptosis inducing factor; AO, acridine orange; DiOC6(3), 3,3′-Dihexyiloxacarbocyanine iodide; FL, fluorescence; FSC, forward light scatter; GA, geldanamycin; Hsp90, heat shock protein 90 kDa; PARP, poly (ADP-rybose) polymerase; PI, propidium iodide;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Geldanamycin promotes nuclear localisation and clearance of PHOX2B misfolded proteins containing polyalanine expansions

Keywords: GA، geldanamycin; GA, geldanamycin; 17-AAG, allylaminogeldanamycin; GFP, green fluorescent protein; HSP, heat shock protein; 7-AAD, 7-amino-actinomycin D; 3-MA, 3-methyladenine; LC, lactacystin; R, rapamycin; MEM, minimal essential medium; FBS, fetal bovine serum; DMSO, di

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones

Keywords: GA، geldanamycin; PMP22, peripheral myelin protein 22; SC, Schwann cell; wt, wild type; HSP, heat shock protein; Lc, lactacystin; DMSO, dimethylsulfoxide; Stv, starvation; 3-MA, 3-methyladenine; GA, geldanamycin; HS, heat shock; GFP, green fluorescent protein; CMT1A, Charc

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Theileria-induced constitutive IKK activation is independent of functional Hsp90

Keywords: GA، geldanamycin; Ab, antibody; EMSA, electrophoretic mobility shift assay; GA, geldanamycin; Hsp90, heat shock protein 90; NEMO, NF-κB essential modulator; NF-κB, nuclear factor kappaB; IKK, IκBα kinase; TNF, tumor necrosis factorChaperone; Signal transduction; Parasite;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Interaction of pro-apoptotic protein HGTD-P with heat shock protein 90 is required for induction of mitochondrial apoptotic cascades

Keywords: GA، geldanamycin; 17-AAG, 17-(Allylamino)-17-demethoxygeldanamycin; DAPI, 4′,6′-diamidino-2-phenylindole; GA, geldanamycin; HIF-1α, hypoxia-inducible factor-1α; Hsp, heat shock protein; MMP, mitochondrial membrane potentialHGTD-P; 90-kDa heat shock protein; Apoptosis; Mito

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه