Keywords: گیرنده های GABAA; Context; GABAA receptors; Zolpidem; Chlordiazepoxide;
مقالات ISI گیرنده های GABAA (ترجمه نشده)
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Keywords: گیرنده های GABAA; CCCs; cation-chloride transporters; GABAAR; GABAA receptors; SE; status epilepticus; CA1; cornus ammonis 1; DG; dentate gyrus; aCSF; artificial cerebrospinal fluid; sulfo-NH-SS-biotin; sulfosuccinimidyl-2-[biotinamido]ethyl-1,3-dithiopropionate; PBS; phos
Keywords: گیرنده های GABAA; Zolpidem; GABAA receptors; Antipsychotic-like effects; Animal models of psychosis; Rats
Keywords: گیرنده های GABAA; 5α-Reductase; Corticotropin-releasing hormone; GABAA receptors; Paraventricular nucleus; Progesterone; Testosterone;
Keywords: گیرنده های GABAA; (+)-borneol; Neuropathic pain; Inflammatory pain; GABAA receptors
Keywords: گیرنده های GABAA; 5α-DHPROG; 5α-dihydroprogesterone; CNS; central nervous system; GABAA receptors; γ-aminobutyric acid type A receptors; GC/MS; gas chromatography/mass spectrometry; 3α-HSOR; 3α-hydroxysteroid oxidoreductase; 3β-HSD; 3β-hydroxysteroid dehydrogenase;
Keywords: گیرنده های GABAA; GABAA receptors; Beta oscillations; Tonic current; Zolpidem; Fast spiking interneurons; Motor cortex; AHP; after-hyperpolarization; aCSF; artificial cerebrospinal fluid; CCh; carbachol; FS; fast spiking; Itonic; tonic inhibitory current; M1; primary motor
Keywords: گیرنده های GABAA; GABAA receptors; Valerenic acid derivatives; Behavioral analysis; 2-Microelectrode-voltage-clamp-technique; LC-MS/MS;
Keywords: گیرنده های GABAA; Genetic models; Absence epilepsy; Rats; WAG/Rij; Mice; Atypical absence models; Typical absence models; AY 9944; Sex differences; Puberty; Neurosteroids; Pregnancy; Ovarian cycle; GABAA receptors; Delta subunits; Alpha subunits
Keywords: گیرنده های GABAA; Picrotoxin (PubChem CID: 442292)Drosophila melanogaster; Locomotor activity; Seizures; GABAA receptors; Rdl; Picrotoxin; Methods
The endogenous agonist, β-alanine, activates glycine receptors in rat spinal dorsal neurons
Keywords: گیرنده های GABAA; β-alanine; Spinal dorsal horn; Glycine receptors; GABAA receptors; Whole-cell patch-clamp; Chloride current;
Structure and dynamics of neurosteroid binding to the α1β2γ2 GABAA receptor
Keywords: گیرنده های GABAA; GABAA receptors; Neurosteroids; α1β2γ2 heteropentamer; Binding sites; Docking, molecular dynamics simulation; Potentiation; Activation;
Sex differences in the synergistic effect of prior binge drinking and traumatic stress on subsequent ethanol intake and neurochemical responses in adult C57BL/6J mice
Keywords: گیرنده های GABAA; Predator odor; Anxiety; GABAA receptors; Corticotrophin releasing factor receptor 1; Prefrontal cortex; Hippocampus;
Automated radiosynthesis and purification of [18F]flumazenil with solid phase extraction
Keywords: گیرنده های GABAA; Fluorine-18; [18F]flumazenil; GABAA receptors; Positron emission tomography; Solid phase extraction; Automated GE TRACERlab FX N Pro synthesizer;
GABAA receptor: Positive and negative allosteric modulators
Keywords: گیرنده های GABAA; γ-Aminobutyric acid type A receptors; Inhibitory neurotransmission; CNS depressant drug target; Anxiolytics/sedatives/general anesthetics; Ethanol; GABA; γ-aminobutyric acid; GABAAR; GABAA receptors; LGIC; ligand-gated ion channels; PLGIC; pentameric LG
Early-life adversity selectively impairs α2-GABAA receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine
Keywords: گیرنده های GABAA; Early-life adversity; Early-life stress; GABAA receptors; Nucleus accumbens; Cocaine;
Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABAA receptor subunit expression and synaptic clustering
Keywords: گیرنده های GABAA; DG; dentate gyrus; EH; early handling; EPM; elevated plus maze; GABA; γ-aminobutyric acid; LD; laterodorsal; MS; maternal separation; NH; non-handled; PND; postnatal day; SS; somatosensory; GABAA receptors; Development; Early-life environment; Stress; In
Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics
Keywords: گیرنده های GABAA; Alphaxalone; Etomidate; Pentobarbital; Propofol; R-5-allyl-1-methyl-5-(m-trifluoromethyl-diazirynylphenyl) barbituric acid (R-mTFD-MPAB); S-1-methyl-5-propyl-5-(m-trifluoromethyl-diazirynylphenyl) barbituric acid (S-mTFD-MPPB); Tetrahydrodeoxycorticostero
Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors
Keywords: گیرنده های GABAA; GABAA receptors; Allosteric modulation; Ago-PAM; AA29504; TEVC electrophysiology;
Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors
Keywords: گیرنده های GABAA; Ago-PAM; allosteric agonist and positive allosteric modulator; C/R; concentration-response; ECD; extracellular domain; FMP; FLIPR Membrane Potential Blue; GABA; γ-Aminobutyric acid; GABAAR; GABAA receptor; methaqualone; 2-methyl-3-(o-tolyl)-quinazolin-4(
Review articleNeuroactive steroids and PTSD treatment
Keywords: گیرنده های GABAA; Neuroactive steroids; Allopregnanolone; Cortisol; Dehydroepiandrosterone; Pregnanolone; 5α-Reductase type I and type 2; 3α-hydroxysteroid dehydrogenase; GABAA receptors; Selective brain steroidogenic stimulants (SBSSs); Endocannabinoids; TSPO ligands; P
A new role for GABAergic transmission in the control of male rat sexual behavior expression
Keywords: گیرنده های GABAA; GABAA receptors; Bicuculline; VTA; Sexual inhibition; Sexual satiety; Male sexual behavior; Mesolimbic system; Sexual responding;
Characterization of 6-methoxyflavanone as a novel anxiolytic agent: A behavioral and pharmacokinetic approach
Keywords: گیرنده های GABAA; 6-Methoxyflavanone (PubChem CID: 97860); Flavonoid; 6-Methoxyflavanone; anxiety; GABAA receptors; elevated plus-maze; staircase anxiety test;
Physiological reviewNot a single but multiple populations of GABAergic neurons control sleep
Keywords: گیرنده های GABAA; Slow wave sleep; Paradoxical sleep; GABAa receptors; GABA; Glycine; Muscle atonia; EEG;
Gephyrin and the regulation of synaptic strength and dynamics at glycinergic inhibitory synapses
Keywords: گیرنده های GABAA; Glycine receptors; GABAA receptors; Inhibitory-excitatory balance; Postsynaptic density actin; Phosphorylation;
Antidepressant, anticonvulsant and antinociceptive effects of 3â²-methoxy-6-methylflavone and 3â²-hydroxy-6-methylflavone may involve GABAergic mechanisms
Keywords: گیرنده های GABAA; GABAA receptors; Flavonoids; Xenopus oocytes; Hot plate test; Forced swim test; Bicuculline;
Behavioural pharmacology of the α5-GABAA receptor antagonist S44819: Enhancement and remediation of cognitive performance in preclinical models
Keywords: گیرنده های GABAA; GABAA receptors; Cognitive performance; Behavioural pharmacology; S44819; Alpha5-GABAA antagonists;
The pervasive reduction of GABA-mediated synaptic inhibition of principal neurons in the hippocampus during status epilepticus
Keywords: گیرنده های GABAA; Status epilepticus; Pyramidal neuron; Dentate granule cell; GABAA receptors; Miniature inhibitory postsynaptic currents;
Short communicationAltered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2+/Q390X mice associated with epileptic encephalopathy
Keywords: گیرنده های GABAA; γ2 subunit; Gabrg2+/Q390X knockin (KI) mice; Gabrg2+/â knockout (KO) mice; Epileptic encephalopathy; Brainstem; GABAA receptors; Protein accumulation;
Surface expression of GABAA receptors in the rat nucleus accumbens is increased in early but not late withdrawal from extended-access cocaine self-administration
Keywords: گیرنده های GABAA; Abstinence; Biotinylation; Cocaine self-administration; GABAA receptors; Incubation of craving; Nucleus accumbens
Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital
Keywords: گیرنده های GABAA; GABAA receptors; Chloride channels; Electrophysiology; Xenopus oocyte; Anesthetics; Barbiturates; GABA; gamma-aminobutyric acid; GABAA receptor; gamma-aminobutyric acid type A receptor;
GABAergic regulation of the HPA and HPG axes and the impact of stress on reproductive function
Keywords: گیرنده های GABAA; Neurosteroids; Stress; GABAA receptors; KCC2; GnRH; Estrous; Puberty; LH; Allopregnanolone; THDOC; Tonic inhibition; Extrasynaptic; Gabrd;
Specificity protein 4 (Sp4) transcriptionally regulates inhibitory GABAergic receptors in neurons
Keywords: گیرنده های GABAA; COX; cytochrome c oxidase; Gabra; gene name for GABAA receptor subunit; Sp4; specificity protein 4; Gene regulation; Sp4; GABAA receptors; Gabra1; Gabra2; Gabra3;
La administración del antagonista GABAA bicuculina previene los efectos de la administración del agonista 5-HT1A 8-OH-DPAT en las propiedades discriminativas de la anfetamina
Keywords: گیرنده های GABAA; Anfetamina; Receptores GABAA; Receptores 5-HT1A; Adicción; Discriminación de drogas; Amphetamine; GABAA receptors; 5-HT1A receptors; Addiction; Drug discrimination;
Enhanced GABAergic inhibition in the premammillary nucleus of photorefractory turkey hens via GABAA receptor upregulation
Keywords: گیرنده های GABAA; AANAT; aralkylamine N-acetyltransferase; β-Actin; actin, beta; CT; circadian time; DA-Mel; dopamine-melatonin; GABA; γ-aminobutyric acid; GAD; glutamate decarboxylase; GnRH-I; gonadotropin-releasing hormone-I; HPRT1; hypoxanthine phosphoribosyltransfera
To what extent is it possible to dissociate the anxiolytic and sedative/hypnotic properties of GABAA receptors modulators?
Keywords: گیرنده های GABAA; Benzodiazepine; GABAA receptors; Subunits; Sedation; Anxiolytic; Tolerance5HT3, serotonin receptor subtypes 3; ACC, anterior cingulate cortex; AChR, acetylcholine receptor; AP2, clathrin-adaptor protein 2; BIG2, brefeldin-A-inhibited GDP/GTP exchange fact
Modulation of GABAA receptors by neurosteroids. A new concept to improve cognitive and motor alterations in hepatic encephalopathy
Keywords: گیرنده های GABAA; HE; hepatic encephalopathy; MHE; minimal hepatic encephalopathya; PCS; portacaval shunt; Hepatic encephalopathy; Hyperammonemia; GABAA receptors; Neuroteroids; Cognitive function; Motor coordination;
Characterization of the fast GABAergic inhibitory action of etifoxine during spinal nociceptive processing in male rats
Keywords: گیرنده های GABAA; Nociception; Pain; Spinal cord; In vivo electrophysiology; GABAA receptors; Synaptic plasticity;
Bud extracts from Tilia tomentosa Moench inhibit hippocampal neuronal firing through GABAA and benzodiazepine receptors activation
Keywords: گیرنده های GABAA; Tilia tomentosa Moench; Anxiolytic drug; Buds; GABAA receptors; Benzodiazepines; Microelectrode array (MEA);
Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site
Keywords: گیرنده های GABAA; GABAA receptors; Chloride channels; Electrophysiology; Xenopus oocyte; Benzodiazepine; Positive allosteric modulator; GABAA receptor; gamma-aminobutyric acid type A receptor; DMSO; dimethylsulfoxide; HEK; human embryonic kidney; SJM-3 (PubChem CID: 497135
Etomidate uniquely modulates the desensitization of recombinant α1β3δ GABAA receptors
Keywords: گیرنده های GABAA; EGTA; ethylene glycol tetraacetic acid; HEK; human embryonic kidney; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; THDOC; tetrahydrodeoxycorticosterone; GABAA receptors; δ subunit; concatemers; etomidate; desensitization; deactivation;
Modulatory effects of inosine, guanosine and uridine on lipopolysaccharide-evoked increase in spike-wave discharge activity in Wistar Albino Glaxo/Rijswijk rats
Keywords: گیرنده های GABAA; NF-κB; nuclear factor kappa B; A2AR; adenosine A2A receptor; Ado; adenosine; AP5; 2-amino-5-phosphonopentanoic acid; CNS; central nervous system; COX-2; cyclooxygenase-2; EEG; electroencephalogram; GABAA receptors; GABAA type of gamma-aminobutyric acid r
Absence epileptic activity changing effects of non-adenosine nucleoside inosine, guanosine and uridine in Wistar Albino Glaxo Rijswijk rats
Keywords: گیرنده های GABAA; A2A receptors; A2A type of Ado receptors; Ado; adenosine; ANOVA; analysis of variance; EEG recording; electroencephalographic recording; GABAA receptors; GABAA type of gamma-aminobutyric acid receptors; GDP; guanosine diphosphate; GMP; guanosine monophosp
Inhibition of microglia in the basolateral amygdala enhanced morphine-induced antinociception: Possible role of GABAA receptors
Keywords: گیرنده های GABAA; AUC; Area under the curve; GABA; Gamma-Aminobutyric acid; i.p.; intraperitoneal; %MPE; Percent of maximum possible effect; Minocycline hydrochloride (PubChem CID: 54685925); Morphine sulfate (PubChem CID: 5464280); Muscimol (PubChem CID: 4266); bicucullin
Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol
Keywords: گیرنده های GABAA; GABA, γ-aminobutyric acid; GABAA receptor, γ-aminobutyric acid type A receptor; 2-AG, 2-arachidonylglycerol; THDOC, tetrahydrodeoxycorticosteroneGABA (γ-aminobutyric acid); GABAA receptors; Honokiol; 4-O-Methylhonokiol
Benzodiazepine modulation of homomeric GABAAÏ1 receptors: Differential effects of diazepam and 4â²-chlorodiazepam
Keywords: گیرنده های GABAA; GABA; γ-aminobutyric acid; GABAA receptors; GABAARs; BDZs; benzodiazepines; TPMPA; (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid; TACA; trans-aminocrotonic acid; CACA; cis-aminocrotonic acid; CNS; central nervous system; TEVC; two electrode volta
Opposite role played by GABAA and GABAB receptors in the modulation of peristaltic activity in mouse distal colon
Keywords: گیرنده های GABAA; Distal colon; Peristaltic activity; Cholinergic contraction; GABAA receptors; GABAB receptors; Mouse
GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G)
Keywords: گیرنده های GABAA; GABAA receptors; Genetic epilepsy; Epilepsy mutation; γ2 subunit R177G mutation; Impaired assembly and trafficking; Protein degradation;
A Novel GABRG2 mutation, p.R136*, in a family with GEFSÂ + and extended phenotypes
Keywords: گیرنده های GABAA; CAE; childhood absence epilepsy; EEG; electroencephalogram; ER; endoplasmic reticulum; FS; febrile seizures; GEFSÂ +; generalised epilepsy with febrile seizures plus; GGE; genetic generalised epilepsy; JME; juvenile myoclonic epilepsy; PTC; premature tran
GABA-induced uncoupling of GABA/benzodiazepine site interactions is mediated by increased GABAA receptor internalization and associated with a change in subunit composition
Keywords: گیرنده های GABAA; GABAA receptors; GABA; benzodiazepine; uncoupling; endocytosis; BSA; bovine serum albumin; EDTA; ethylenediaminetetraacetic; FNZ; flunitrazepam; HRP; horseradish peroxidase; PBS; phosphate-buffered saline; PMSF; phenylmethylsulfonyl fluoride; RIPA; radioi