Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; BSA, bovine serum albumin; CB, calbindin; CeM, medial part of the central nucleus of amygdala; ChAT, choline acetyltransferase; CLSM, confocal laser scanning light microscopy; CR, calretinin; EPN, entopeduncular nucleus; GAD, glutamic acid decarboxylase;
مقالات ISI GAD، اسید گلوتامیک دکربوکسیلاز (ترجمه نشده)
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Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Ab, antibody; BMI, body mass index; CXCL1, chemokine ligand 1; DPT-1, Diabetes Prevention Trial 1; DPTRS, DPT-1 risk score; ER, endoplasmic reticulum; GAD, glutamic acid decarboxylase; HLA, human leukocyte antigen; IA2, insulinoma antigen 2; IAA, insulin
Repeated forced swim stress affects the expression of pCREB and ΔFosB and the acetylation of histone H3 in the rostral ventromedial medulla and locus coeruleus
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ABC, avidin-biotin-peroxidase complex; BSA, bovine serum albumin; CBP, CREB-binding protein; CCK, cholecystokinin; CFA, complete Freund’s adjuvant; CREB, cAMP response element-binding protein; FS, forced swim stress; GAD, glutamic acid decarboxylase; HAT,
Postnatal development and sensory experience synergistically underlie the excitatory/inhibitory features of hippocampal neural circuits: Glutamatergic and GABAergic neurotransmission
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA, analysis of variance; DR, dark-reared; fEPSPs, field excitatory postsynaptic potential; GABA, Gamma-amino-butyric acid; GAD, Glutamic acid decarboxylase; HFS, High frequency stimulation; L
Linkage disequilibrium with HLA-DRB1-DQB1 haplotypes explains the association of TNF-308G>A variant with type 1 diabetes in a Brazilian cohort
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ANOVA, analysis of variance; CI, confidence interval; DN, diabetic nephropathy; DNA, deoxyribonucleic acid; GAD, glutamic acid decarboxylase; HbA1C, glycated hemoglobin; HDL, high density lipoprotein; HLA, human leukocyte antigen; HWE, Hardy–Weinberg equi
Frameshift mutations in the insulin gene leading to prolonged molecule of insulin in two families with Maturity-Onset Diabetes of the Young
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Diabetes; MODY; insulin gene; mutationBMI, body mass index; DCCT, Diabetes Control and Complications Trial; ER, endoplasmatic reticulum; GAD, glutamic acid decarboxylase; GCK, glucokinase; HNF1A, hepatocyte nuclear factor 1-alpha; HNF4A, hepatocyte nuclea
Immunological GABAergic interactions and therapeutic applications in autoimmune diseases
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CIA, collagen-induced arthritis; EAE, experimental autoimmune encephalomyelitis; GABA, gamma-aminobutyric acid; GABAAR, type A GABA receptor; GABABR, type B GABA receptor; GABA-T, GABA transaminase; GAD, glutamic acid decarboxylase; GAT, GABA transporter;
Menin regulates spinal glutamate-GABA balance through GAD65 contributing to neuropathic pain
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; aCSF, artificial cerebral spinal fluid; CNS, central nervous system; EPSCs, excitatory post-synaptic currents; GABA, γ-aminobutyric acid; GAD, glutamic acid decarboxylase; GAD65-rAAV2, glutamic acid decarboxylase 65-recombinant adeno-associated virus vect
nNOS inhibition during profound asphyxia reduces seizure burden and improves survival of striatal phenotypic neurons in preterm fetal sheep
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Asphyxia; Basal ganglia; nNOS; Neuroprotection; Preterm fetus; SeizuresCaBF, carotid arterial blood flow; ChAT, choline acetyl transferase; CP, cerebral palsy; EEG, electroencephalography; GAD, glutamic acid decarboxylase; HI, hypoxia-ischemia; nNOS, neur
A case of childhood stiff-person syndrome with striatal lesions: A possible entity distinct from the classical adult form
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; DWI, diffusion-weighted imaging; GAD, glutamic acid decarboxylase; SPECT, single-photon emission computed tomography; SPS, stiff-person syndromeChild; Diffusion-weighted imaging; MRI; SPECT; Stiff-person syndrome; Striatum
Cadmium exposure in relation to insulin production, insulin sensitivity and type 2 diabetes: A cross-sectional and prospective study in women
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; BMI, Body mass index; GAD, Glutamic acid decarboxylase; HOMA-IR, Homeostasis model assessment-estimated insulin resistance; IGT, Impaired glucose tolerance; NGT, Normal glucose tolerance; OGTT, Oral glucose tolerance testCadmium; Type 2 diabetes; Glucose
Epigenetic control of neurotransmitter expression in olfactory bulb interneurons
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; acH3, acetylated Histone H3; ChIP, chromatin immunoprecipitation; GABA, gamma aminobutyric acid; GAD, glutamic acid decarboxylase; HDAC, histone deacetylase; NRSE, neural restrictive silencer elements; OB, olfactory bulb; qPCR, quantitative polymerase cha
Adolescent female C57BL/6 mice with vulnerability to activity-based anorexia exhibit weak inhibitory input onto hippocampal CA1 pyramidal cells
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; AN, anorexia nervosa; ABA, activity-based anorexia; BSA, bovine serum albumin; CON, control mice; DAB, 3,3′-diaminobenzidine-hydrochloride; FAA, food anticipatory activity; FR, food restriction; GAD, glutamic acid decarboxylase; GFP, green fluorescent pro
Development of an ultra-sensitive enzyme immunoassay for human insulin autoantibodies
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ICT-EIA, immune-complex transfer enzyme immunoassay; ELISA, enzyme-linked immunosorbent assay; BSA, bovine serum albumin; DNP, 2,4-dinitrophenyl; FI, fluorescence intensity; GAD, glutamic acid decarboxylase; IA-2, insulinoma-associated antigen-2; LADA, la
Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; AMPA, α-amino-3-hydroxy-5-methylisoxazole-4-propionate; DA, dopamine; DOPAC, dihydroxyphenyl acetic acid; HVA, homovanilic acid; 5-HT, 5-hydroxytriptamine; 5-HIAA, 5-hydroxyindoleacetic acid; GAD, glutamic acid decarboxylase; GFAP, glial fibrillary acidic
Immunohistochemical evidence for synaptic release of GABA from melanin-concentrating hormone containing varicosities in the locus coeruleus
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Cy, cyanine; GAD, glutamic acid decarboxylase; Geph, gephyrin; LC, locus coeruleus; LDCV, large dense core vesicles; MCH, melanin-concentrating hormone; NA, noradrenaline; Orx, orexin; PS, paradoxical sleep; REM, rapid eye movement; SSV, small synaptic ve
1H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CPMG, Carr-Purcell-Meiboom-Gill; FIDs, free induction decays; GABA, gamma-aminobutyric acid; GAD, glutamic acid decarboxylase; M-Ins, myo-inositol; NAA, N-acetyl aspartate; NAc, nucleus accumbens; NMDA, N-methyl-d-aspartate; NMR, nuclear magnetic resonanc
Targeting inhibitory neurotransmission in tinnitus
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CSF, cerebrospinal fluid; DCN, dorsal cochlear nucleus; FBN, Fischer Brown Norway; GABA, γ-aminobutyric acid; GABARAP, GABAA receptor associated protein; GAD, glutamic acid decarboxylase; GlyR, glycine receptor; GABAAR, GABAA receptor; GABA-T, GABA transa
Differential molecular regulation of glutamate in kindling resistant rats
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; EAAC-1, excitatory amino acid carrier-1; GABA, gamma-aminobutyric acid; GAD, glutamic acid decarboxylase; GLAST, glutamate-aspartate transporter; GLT-1, glutamate transporter-1; GS, glutamine synthetase; PAG, phosphate-activated glutaminase; PTZ, pentylen
GCKR mutations in Japanese families with clustered type 2 diabetes
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; GAD, glutamic acid decarboxylase; GCKR, glucokinase regulator; HLOD, heterogeneity logarithm of the odds; HNF4α, Hepatocyte Nuclear Factor 4α; LOD, logarithm of the odds; MAF, minor allele frequency; MODY, maturity onset diabetes of the young; RFLP, restr
Developmental plasticity of auditory cortical inhibitory synapses
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ACx, auditory cortex; BDNF, brain-derived neurotrophic factor; CHL, conductive hearing loss; FS, fast-spiking; GABA, gamma-aminobutyric acid; GAD, glutamic acid decarboxylase; IC, inferior colliculus; IPSC, inhibitory postsynaptic current; IPSP, inhibitor
Contribution of metabotropic GABAB receptors to neuronal network construction
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CNS, Central Nervous System; CREB, cAMP Response Element Binding protein; BDNF, Brain-Derived Neurotrophic Factor; GIRK, G-protein activated inwardly rectifying potassium channel; GABA, γ-Amino-Butyric Acid; GAD, Glutamic Acid Decarboxylase; IP3, Inositol
Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases – An unrevealed role in downregulation of Th17 cells
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Pre-ligand assembly domain; Th17; NOD mice; Experimental autoimmune encephalomyelitisPLAD, pre-ligand assembly domain; GAD, glutamic acid decarboxylase; MOG, myelin oligodendrocyte glycoprotein; PLN, pancreatic lymph node; APCs, antigen presenting cells;
IL-7 uniquely maintains FoxP3+ adaptive Treg cells that reverse diabetes in NOD mice via integrin-β7-dependent localization
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; Diabetes; Regulatory T cell; NOD mouse; IL-7; Integrin-β7T1D, Type 1 diabetes mellitus; NOD, Non-Obese Diabetic; PLN, Pancreatic lymph node; B6, C57BL/6J; GAD, glutamic acid decarboxylase; IA, insolenoma antigen; ZnT8, islet zinc transporter; Treg, Regula
GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; 4AP, 4-aminopyridine; BIC, bicuculline; CA1 and CA3, Cornus Ammonis subfield 1 and 3; [Cl−]i, intracellular Cl− concentration; DG, dentate gyrus; EC, entorhinal cortex; GAD, glutamic acid decarboxylase; [K+]i, intracellular K+ concentration; LLD, long-las
The sexual difference of aging-associated functional degradation in visual cortical cells of rats
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; GABA, gamma-aminobutyric acid; CFF, critical flicker frequency; PSTHs, poststimulus time histograms; GAD, glutamic acid decarboxylase; ChAT, choline acetyltransferase; AI, adaptation indexAging; Sexual difference; Rat; Signal-to-noise ratio; Visual cortex
Ethanol increases GABA release in the embryonic avian retina
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CNS, central nervous system; EAA, excitatory amino acids; EtOH, ethanol; FASD, fetal alcohol spectrum desorder; GABA, γ-aminobutyric acid; GAD, glutamic acid decarboxylase; GAT1, GABA transporter 1; INL, inner nuclear layer; NMDA, n-methyl d-aspartate; NR
Acanthosis Nigricans Identifies Youth at High Risk for Metabolic Abnormalities
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; AN, Acanthosis nigricans; AN+, With acanthosis nigricans; AN−, Without acanthosis nigricans; BMI, Body mass index; DM, Diabetes mellitus; GAD, Glutamic acid decarboxylase; HDL, High-density lipoprotein; HOMA-IR, Homeostasis model assessment of insulin res
D2 and D4 dopamine receptor mRNA distribution in pyramidal neurons and GABAergic subpopulations in monkey prefrontal cortex: implications for schizophrenia treatment
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; calbindin; co-localization; glutamatergic neurons; in situ hybridization; parvalbuminCB, calbindin; DLPFC, dorsolateral PFC; GAD, glutamic acid decarboxylase; OFC, orbitofrontal cortex; PBS, phosphate-buffered saline; PFC, prefrontal cortex; PV, parvalbum
Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; aCSF, Artificial cerebro-spinal fluid; CV, Coefficient of variation; GABA, γ-amino-butyric acid; GAD, Glutamic acid decarboxylase; GAT, GABA transporter; GAT-1, GABA transporter type 1; GAT-3, GABA transporter type 3; GP, Globus pallidus; GPe, External se
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; VNC, vestibular nucleus complex; CE, cerebellum; VOR, vestibulo-ocular reflex; 5-HT, 5-hydroxytryptamine; GABA, γ–aminobutyric acid; GAD, glutamic acid decarboxylase; NMDA, N-methyl-d-aspartate; AMPA, α-amino-3-hydroxyl-5-methyl; NOS, nitric oxide synthas
Loss of spinal glycinergic neurons is not necessary for development of neuropathic pain in transgenic mice expressing enhanced green fluorescent protein in glycinergic neurons
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; neuropathic pain; glycinergic transmission; cell death; chronic constriction injuryCCI, chronic constriction injury; EGFP, enhanced green fluorescent protein; GAD, glutamic acid decarboxylase; GlyT, glycine transporter; IPSC, inhibitory postsynaptic curre
Peptidylarginine deiminases and the pathogenesis of rheumatoid arthritis: A reflection of the involvement of transglutaminase in coeliac disease
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ACPA, anti-citrullinated peptide antibody; CD, coeliac disease; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; EMA, endomysial antibodies; FXIII, factor XIII; GAD, glutamic acid decarboxylase; MTX, methotrexate; PAD, peptidylarginine deiminas
Postnatal changes in expression of vesicular glutamate transporters in the main olfactory bulb of the rat
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; VGLUT1; VGLUT2; development; in situ hybridization; immunohistochemistryABC, avidin–biotin–peroxidase complex; DIG, digoxigenin; E, embryonic day; EPL, external plexiform layer; FISH, fluorescence in situ hybridization; GAD, glutamic acid decarboxylase; G
Effects of the food contaminant semicarbazide following oral administration in juvenile Sprague–Dawley rats
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ADC, azodicarbonamide; CNS, central nervous system; ECM, extracellular matrix; EFSA, European Food Safety Authority; GABA, gamma-aminobutyric acid; GAD, glutamic acid decarboxylase; PND, postnatal day; SAP, stretched-attend postures; SD, standard deviatio
Behavioral and degeneration changes in the basal forebrain systems of aged rats: A quantitative study in the region of the basal forebrain after levo-acetyl-carnitine treatments assessed by Abercrombie estimation
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ACh, acetylcholine; BF, basal forebrain; ChAT, choline acetyltransferase; DAB, 3′-3′-diaminobenzidine; DBB, diagonal band of Broca; GAD, glutamic acid decarboxylase; GP, globus pallidus; LHa, lateral anterior hypothalamus; LPOA, lateral preoptic area; MCP
Neurochemistry of bulbospinal presympathetic neurons of the medulla oblongata
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; 5HT, 5-hydoxytryptamine (serotonin); Cal, calbindin; CART, cocaine- and amphetamine-regulated transcript; DBH, dopamine-beta-hydroxylase; ENK, enkephalin; EPSP, excitatory postsynaptic potential; GAD, glutamic acid decarboxylase; GLY, glycine; ir, immunor
Evidence That Increased 5-HT Release Evokes Region-Specific Effects on Blood-Oxygenation Level-Dependent Functional Magnetic Resonance Imaging Responses in the Rat Brain
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; fMRI; BOLD; 5-HT; fenfluramineBOLD, blood oxygenation level dependent; fMRI, functional magnetic resonance imaging; EACC1, excitatory amino acid carrier 1; GAD, glutamic acid decarboxylase; pCPA, p-chlorophenylalanine; PET, positron emission tomography; R
The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ACh, acetylcholine; ChAT, choline acetyltransferase; DKO, double knockout; GAD, glutamic acid decarboxylase; PCA, perchloric acid; SDS, sodium dodecyl sulphate; SV2A, synaptic vesicle protein 2A; VAChT, vesicular acetylcholine transporter; VGAT, vesicular
Temporal and topographic alterations in expression of the α3 isoform of Na+,K+-ATPase in the rat freeze lesion model of microgyria and epileptogenesis
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; sodium pump; cortical malformation; pyramidal cell; parvalbumin-containing interneuron; epilepsy; injuryCT, contralateral; DEPC, diethyl pyrocarbonate; FL, freeze lesion; GAD, glutamic acid decarboxylase; IR, immunoreactivity; P, postnatal day; PV, parval
Maps of cardiovascular and respiratory regions of rat ventral medulla: Focus on the caudal medulla
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; AP, arterial pressure; C1, cervical segment 1; CMM, caudal midline medulla; CPA, caudal pressor area; CVLM, caudal ventrolateral medulla; cVRG, caudal ventral respiratory group; GABA, gamma amino butyric acid; GAD, glutamic acid decarboxylase; GiDa, gigan
Altered synchrony and connectivity in neuronal networks expressing an autism-related mutation of neuroligin 3
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; neuronal activity; neuronal communication; complexity; lacunarity; calcium imaging; neuronal degenerationASD, autism spectrum disorders; BSA, bovine serum albumin; CFP, pECFP-C1; EBS, extracellular bath solution; GAD, glutamic acid decarboxylase; I/E, inh
GABAergic and glycinergic interneuron expression during spinal cord development: Dynamic interplay between inhibition and excitation in the control of ventral network outputs
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CNS, central nervous system; CPG, central pattern generator; E, embryonic age; ECl, chloride reversal potential; P, postnatal day; IR, immuno-reactive; GAD, glutamic acid decarboxylase; BDNF, brain-derived neurotrophic factor; 5-HT, 5-hydroxytryptamine, s
Incidence of children with slowly progressive form of type 1 diabetes detected by the urine glucose screening at schools in the Tokyo Metropolitan Area
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; LADA, latent autoimmune diabetes in adults; SPT1D, slowly progressive form of type 1 diabetes; OGTT, oral glucose tolerance test; ICA, islet cell antibodies; GAD, glutamic acid decarboxylase; BMI, body mass index; JDF U, Juvenile Diabetes Foundation units
Gene delivery GAD500 autoantigen by AAV serotype 1 prevented diabetes in NOD mice: Transduction efficiency do not play important roles
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; GAD, glutamic acid decarboxylase; NOD, non-obese diabetic; AAV, adeno-associated virusAutoimmune diabetes; Gene therapy; AAV-1; AAV-2
The effect of electroacupuncture on spontaneous recurrent seizure and expression of GAD67 mRNA in dentate gyrus in a rat model of epilepsy
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; EA, electroacupuncture; SRS, spontaneous recurrent seizure; DG, dentate gyrus; St36, Zusanli; GCL, granule cell layer; GAD, glutamic acid decarboxylase; TLE, temporal lobe epilepsy; SE, status epilepticus; MOD, mean density opticalEpilepsy; Electroacupunc
Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; ANOVA, analysis of variance; CMV, cytomegalovirus; EBV, Epstein-Barr virus; GAD, glutamic acid decarboxylase; HS, human serum; IA-2, insulinoma-associated protein 2; IGRP, islet glucose-6-phosphatase catalytic subunit related protein; MP, matrix protein;
GABAB receptors role in cell migration and positioning within the ventromedial nucleus of the hypothalamus
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; hypothalamic development; migration; GABAB receptors; estrogen receptors; arcuate nucleusARC, arcuate nucleus; BDNF, brain-derived neurotrophic factor; E, embryonic day; ER, estrogen receptor; GAD, glutamic acid decarboxylase; GFP, green fluorescent prote
Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; aab, autoantibodies; cpm, counts per minute; GAD, glutamic acid decarboxylase; GADA, autoantibodies to glutamic acid decarboxylase; IA-2, insulinoma antigen 2; IA-2A, autoantibodies to insulinoma antigen 2; IAA, autoantibodies to insulin; IC50, 50% inhibi
Characterization of green fluorescent protein-expressing retinal cells in CD 44-transgenic mice
Keywords: GAD، اسید گلوتامیک دکربوکسیلاز; CD44; retina; amacrine cell; ganglion cell; transgenic miceCD44, cluster of differentiation 44; ChAT, choline acetyltransferase; EGFP, enhanced green fluorescent protein; GAD, glutamic acid decarboxylase; GFP, green fluorescent protein; INL, inner nuclear