Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; HPLC, high performance liquid chromatography; SPE, solid phase extraction; FACE, fluorophore assisted carbohydrate electrophoresis; UDP, uridine diphosphate; GDP, guanosine diphosphate; CMP, cytosine monophosphate; TEAA, triethylamine acetate; APS, ammoni
مقالات ISI تولید ناخالص داخلی، گوانوزین دی فسفات (ترجمه نشده)
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Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Autophagy; Rab GTPase; Size exclusion chromatography; Thermodynamics; GST-pull downAtg, autophagy related proteins; ITC, isothermal titration calorimetry; GST, glutathione -S-transferase; SEC, size exclusion chromatography; GDP, guanosine diphosphate; GTP
Epigenetic regulation of G protein coupled receptor signaling and its implications in psychiatric disorders
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; GPCRs, Gprotein-coupled receptors; HDAC, histone deacetylase; CNS, central nervous system; GWAS, genome-wide association studies; GEFs, guanine nucleotide exchange factors; GDP, guanosine diphosphate; GTP, guanosine triphosphate; WHO, world health organiz
Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1)
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; 2-BP, 2-bromopalmitate; Cdc42, cell division control protein 42; DCFDA, 2′,-7′-dichlorofluorescein diacetate; GDP, guanosine diphosphate; GTP, guanosine triphosphate; GGTI, geranylgeranyl transferase inhibitor; GSIS, glucose stimulated insulin secretion;
Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Endosome; Pancreatitis; PIKfyve; TrypsinAP, adaptor protein; BFA, brefeldin A; CCK, cholecystokinin; CLP, constitutive-like pathway; DMEM, Dulbecco’s minimal essential medium; DMSO, dimethyl sulfoxide; EE, early endosome; GDP, guanosine diphosphate; GFP,
Characterization of 5-HT1A receptors and their complexes with G-proteins in budded baculovirus particles using fluorescence anisotropy of Bodipy-FL-NAN-190
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; G-protein, guanine nucleotide binding protein; GPCR, G-protein coupled receptor; 5-HT1A, 5-hydroxytryptamine (serotonin) receptor 1A; Sf9, Spodoptera frugiperda 9; GDP, guanosine diphosphate; GTPγS, guanosine 5′-O-[gamma-thio]triphosphate; 5-HT, 5-hydroxy
Dynamic and Thermodynamic Response of the Ras Protein Cdc42Hs upon Association with the Effector Domain of PAK3
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ASA, accessible surface area; CRIB, Cdc42/Rac interactive binding; CSA, chemical shift anisotropy; GAP, GTPase-activating protein; GDI, guanine nucleotide dissociation inhibitor; GDP, guanosine diphosphate; GEF, guanine nucleotide exchange factor; GTP, gu
Dynamic metabolic flux analysis of plant cell wall synthesis
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; NDP-sugars, nucleotide-sugars; Api, apiose; Ara, arabinose; Fuc, fucose; Fru, fructose; Gal, galactose; GalA, galacturonic acid; GDP, guanosine diphosphate; Glc, glucose; GlcA, glucuronic acid; Man, mannose; P, phosphate; Rha, Rhamnose; Xyl, xylose; Suc,
The rhodopsin-transducin complex houses two distinct rhodopsin molecules
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; b2AR, β2-adrenergic receptor; Bis–Tris propane, 1,3-bis[tris(hydroxymethyl)-methylamino]propane; CTF, contrast transfer function; DDM, n-dodecyl-β-d-maltoside; DSG, disuccinimidyl glutarate; DTT, dithiothreitol; GDP, guanosine diphosphate; GTP, guanosine
Uncoupling protein-2 expression and effects on mitochondrial membrane potential and oxidant stress in heart tissue
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ADP, adenosine diphosphate; AU, arbitrary unit; BSA, bovine serum albumin; DTNB, 5,5’dithio-bis-2-nitrobenzoic acid; EGTA, ethylene glycol tetraacetic acid; FU, fluorescent unit; GDP, guanosine diphosphate; KO, knockout; MIB, mitochondrial isolation buffe
Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ATC, anaplastic thyroid carcinoma; Epac, exchange protein directly activated by cAMP; FSK, forskolin; GEF, guanine nucleotide exchange factor; GDP, guanosine diphosphate; GTP, guanosine triphosphate; MDS, multidimensional scaling; PKA, protein kinase A; P
The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; BSA, bovine serum albumin; cAMP, cyclic 3′,5′-adenosine monophosphate; DPCPX, 1,3-dipropyl-8-cyclopentyl-1,3-dipropylxanthine; DTT, dithiothreitol; EGTA, etylene glycol-bis ((-aminoethyl ether); GDP, guanosine diphosphate; GPCR, G protein-coupled receptor
Formation of the immunogenic α1,3-fucose epitope: Elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Fucosyltransferase; CCD; Progress curve analysis; STD NMRFucTA, fucosyltransferase A; STD, saturation transfer difference; NMR, nuclear magnetic resonance; GDP, guanosine diphosphate; CCD, cross-reactive carbohydrate determinant; FUT8, core α1,6-fucosyltr
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; AAPCC, American Association of Poison Control Centers; BSA, bovine serum albumin; CB1R, cannabinoid 1 receptor; Δ9-THC, delta-9-tetrahydrocannabinol; GDP, guanosine diphosphate; GTPγS, guanosine 5′-O-[gamma-thio]triphosphate; GPCR, G-protein coupled recep
Endothelins & erectile dysfunction
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ED, erectile dysfunction; QoL, quality of life; CC, corpora cavernosa; Ca2+, calcium; ET, endothelin; ET-1, endothelin-1; ET-2, endothelin-2; ET-3, endothelin-3; SMCs, smooth muscle cells; GDP, guanosine diphosphate; GTP, guanosine triphosphate; cGMP, cyc
Cyclic di-GMP Activation of Polynucleotide Phosphorylase Signal-Dependent RNA Processing
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; c-di-GMP, cyclic diguanylic acid; DOS-RNC, Dos ribonucleoprotein complex; GTP, guanosine triphosphate; GDP, guanosine diphosphate; DosC, direct O2-sensing cyclase; DosP, direct O2-sensing phosphodiesterasedegradosome; EAL domain; GGDEF domain; oxygen sens
Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ADP, adenosine diphosphate; dNDP, deoxy-ribonucleoside diphosphate; GDP, guanosine diphosphate; h, hours; PNP, purine ribonucleoside phosphorylase; PPi, pyrophosphate; TDP, thymidine diphosphate; VAL, validamycin A; VO, validoxylamine A; UDP, uridine diph
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Ado, adenosine; ADP, adenosine diphosphate; AMP, adenosine monophosphate; ATP, adenosine triphosphate; BBB, blood brain barrier; Ca2+, calcium; Cl−, chloride; ECP, energy charge potential; GDP, guanosine diphosphate; GMP, guanosine monophosphate; GSH, glu
Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; TG2, transglutaminase 2; ATP, adenosine triphosphate; GDP, guanosine diphosphate; GTP, guanosine triphosphateTransglutaminase 2; Crystal structure; Adenosine triphosphate; ATP
Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [35S] guanosine 5′-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; autoradiography; G-protein; U-69593AcC, accumbens core; AcS, accumbens shell; BLA, basolateral amygdala; CO2, carbon dioxide; CPu, caudate putamen; DA, dopamine; G-protein, guanine nucleotide-binding protein; GDP, guanosine diphosphate; GTPγS, guanosine 5
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; ATP, adenosine triphosphate; ADP, adenosine diphosphate; Pi, inorganic orthophosphate; GTP, guanosine triphosphate; GDP, guanosine diphosphate; NAD+, nicotinamide adenine dinucleotide (oxidized form); NADH, nicotinamide adenine dinucleotide (reduced form)
Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; eIF4E; Translation initiation; Anticancer; Antifibrotic; CoMFA; CoMSIABn7-GMP, N7-benzylated guanosine monophosphate; GDP, Guanosine diphosphate; GTP, Guanosine triphosphate; EWG, Electron withdrawing group; EDG, Electron donating group; ESI-MS, Electrosp
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; IgG, immunoglobulin G; GTP, guanosine triphosphate; GDP, guanosine diphosphate; FITC, fluorescein isothiocyanate; ANS, 1-anilinonaphthalene-8-sulfonic acid; EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; DAMA–colchicine, N-deace
The R1441C mutation alters the folding properties of the ROC domain of LRRK2
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; DSF, differential scanning fluorimetry; CD, circular dichroism; GDP, guanosine diphosphate; GTP, guanosine triphosphate; LRRK2, leucine rich repeat kinase 2; ROC, Ras of complex proteins; PD, Parkinson's diseaseLRRK2; ROCO protein; GTPase; Parkinson's dis
Gtr1p differentially associates with Gtr2p and Ego1p
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; TOR, target of rapamycin; SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; GTP, Guanosine Triphosphate; GDP, Guanosine Diphosphate; DBD, DNA binding domain; AD, Activation Domain; HA, hemagglutinin; Mr, Molecular weight; PDB, Protein D
P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Ras; p120-RasGAP; SH2 domain; SH3 domainp120-RasGAP, Ras GTPase activating protein; GDP, guanosine diphosphate; GTP, guanosine triphosphate; GTPase, guanosine triphosphatase; GAP, GTPase-activating proteins; Dok, downstream of tyrosine kinase; PI-3K, phos
Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; DSP, digital signal processing; EIIP, electron–ion interaction potential; GDP, guanosine diphosphate; GTP, guanosine triphosphate; IC50, half maximal inhibitory concentration; MTs, microtubules; PDB, protein data bank; RSA, relative solvent accessibility;
Cloning and characterization of a salt stress-inducible small GTPase gene from the model grass species Lolium temulentum
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; COR413; Dehydration stress; GTPase; Lolium temulentum; Salt stressABA, abscisic acid; GTP, guanosine triphosphate; GDP, guanosine diphosphate; NaCl, sodium chloride; ORF, open reading frame; PCR, polymerase chain reaction; PEG, polyethylene glycol; RACE,
Compensatory and Long-Range Changes in Picosecond–Nanosecond Main-Chain Dynamics upon Complex Formation: 15N Relaxation Analysis of the Free and Bound States of the Ubiquitin-like Domain of Human Plexin-B1 and the Small GTPase Rac1
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; GAP, GTPase-activating protein; GEF, guanine exchange factor; GDI, GDP dissociation inhibitor; GDP, guanosine diphosphate; GMPPNP, guanosine-5′-[(β,γ)-imido]triphosphate triethylammonium salt; GTP, guanosine triphosphate; GTPase, guanosine 5′-triphosphata
Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; GEF, guanine nucleotide exchange factor; CRD, cysteine-rich domain; DH, Dbl homology; CR, conserved region; EM, electron microscopy; SAXS, small-angle X-ray scattering; GDP, guanosine diphosphate; GTP, guanosine triphosphate; PH, pleckstrin homology; GNE,
Molecular characterization and expression analysis of nine cotton GhEF1A genes encoding translation elongation factor 1A
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; cDNA, DNA complementary to RNA; EF, elongation factor; GhEF1A, cotton gene for translation elongation factor 1A; GTP, guanosine triphosphate; GDP, guanosine diphosphate; ORF, open reading frame; RT-PCR, reverse transcriptase-polymerase chain reaction; PGE
Transglutaminase 2 inhibitors and their therapeutic role in disease states
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Transglutaminase; Inhibitors; Chemical structures; Celiac sprue; Neurodegeneration; CancerECM, extracellular matrix; GDP, guanosine diphosphate; GPR56, G protein-coupled receptor 56; GTP, guanosine triphosphate; HLA, human leukocyte antigen; NF-κB, nuclea
Anisakis simplex: CO2-fixing enzymes and development throughout the in vitro cultivation from third larval stage to adult
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; Anisakis simplex; Nematode; Anisakiasis; pCO2; Development; CO2-fixation; Phosphoenolpyruvate carboxylase; Phosphoenolpyruvate carboxykinase; ATP, adenosine triphosphate; EDTA, ethylene diamine tetraacetic acid; GDP, guanosine diphosphate; IDP, inosine di
SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2′methyl-4′-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): A novel, potent and selective 5-HT1B receptor antagonist
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; 5-HT1B receptor; SB-616234-A; Human; Rat; Guinea pigCHO, Chinese hamster ovary; GDP, guanosine diphosphate; h, human; MAOI, monoamine oxidase inhibitor; PEI, polyethylenimine; SB-616234-A, 1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1
A Molecular-Mechanical Model of the Microtubule
Keywords: تولید ناخالص داخلی، گوانوزین دی فسفات; MT, microtubule; PF, protofilament; Rad, radian; GTP, guanosine triphosphate; GDP, guanosine diphosphate