دانلود مقالات ISI درباره Ggtase + ترجمه فارسی

آیا داروهای مهار کننده مسیر مونولونات نیز سلول های بنیادی سرطانی را هدف قرار می دهند؟

Could drugs inhibiting the mevalonate pathway also target cancer stem cells?

Keywords: Cancer stem-like cells; Mevalonate cascade; Ras; Rho; Stemness; Statins; Yap; ACAT; acetoacetyl-CoA transferase; acetyl-CoA; acetyl-coenzyme A; Arp2/3; actin-related protein 2/3 (actin polymerizing complex); BPs; bisphosphonates; CAMs; cell adhesion molec

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

مهار فعالیت پری زیلترانسفراز توسط استاتین ها در هر دو سلول های کبد و سلول های عضلانی سبب ایجاد سمیت سلولی نمی شود

Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity

Keywords: HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; FTase; farnesyl transferase; GGTase; geranylgeranyl transferase; Statin toxicity; Prenylation; Cholesterol; HMG COA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

مکمل رژیم غذایی روغن دانه کتان باعث کاهش اثر سیپلاتین بر روی کلیه های موش صحرایی می شود

Dietary supplementation of flaxseed oil ameliorates the effect of cisplatin on rat kidney

Keywords: ACPase; acid phosphatase; AKI; acute renal injury; ALP; alkaline phosphatase; BBM; brush border membrane; BBMV; brush border membrane vesicles; BUN; blood urea nitrogen; CP; cisplatin; CPFXO; cisplatin-flaxseed oil; FXO; flaxseed oil; FBPase; fructose-1,6

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

KRAS-Mutant non-small cell lung cancer: From biology to therapy

Keywords: BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Production of authentic geranylgeranylated KRAS4b using an engineered baculovirus system

Keywords: Prenylation; RAS; Geranylgeranylation; Protein production; Baculovirus; FNT; farnesyltransferase; GGTase; geranylgeranyltransferase; MBP; maltose-binding protein; FMe; farnesylated and methylated; GGMe; geranylgeranylated and methylated; GG; geranylgerany

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular genetics ‎characterization and homology modeling of the CHM gene mutation: A study on its association with choroideremia

Keywords: CHM; choroideremia; RPE; retinal pigment epithelium; REP-1; Rab escort protein-1; VA; visual acuity; OCT; optical coherence tomography; GGTase; geranylgeranyltransferase; ONL; outer nuclear layer; INL; inner nuclear layer; LCHADD; long-chain 3-hydroxyacyl

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on brush border membrane enzymes, carbohydrate metabolism and antioxidant system in rat intestine

Keywords: ACPase; acid phosphatase; ALP; alkaline phosphatase; BBM; brush border membrane; BBMV; BBM vesicles; CAT; catalase; CP; cisplatin; FBPase; fructose 1,6-bisphosphatase; G6Pase; glucose 6-phosphatase; G6PDH; glucose 6-phosphate dehydrogenase; GGTase; γ-glu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Prenylation differentially inhibits insulin-dependent immediate early gene mRNA expression

Keywords: Insulin; Gene expression; Transcription; Immediate early genes; Prenylation; FTase; Farnesyl transferase; GGTase; Geranylgeranyl transferase; HFPA; α-hydroxyfarnesylphosphonic acid; GGTI; Geranylgeranyl transferase inhibitor GGTI-286;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation

Keywords: statins; isoprenoids; protein prenylation; synaptic plasticity; hippocampus; long-term potentiation; aCSF; artificial cerebral spinal fluid; AD; Alzheimer's disease; Akt; protein kinase B; fEPSPs; field excitatory postsynaptic potentials; FPP; farnesyl py

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Vitamin C attenuates potassium dichromate-induced nephrotoxicity and alterations in renal brush border membrane enzymes and phosphate transport in rats

Keywords: AP; alkaline phosphatase; ARF; acute renal failure; BBM; brush border membrane; BBMV; BBM vesicles; BUN; blood urea nitrogen; Cu–Zn SOD; copper–zinc superoxide dismutase; Cr; chromium; GGTase; gamma-glutamyl transferase; GSH; glutathione; HEPES; N-2-hydro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Spectroscopic study of fluorescent peptides for prenyl transferase assays

Keywords: CMC; critical micelle concentration; DM; n-dodecyl-β-d-maltoside; DTT; dithiothreitol; FMOC; fluorenylmethoxycarbonyl; FPP; farnesyl pyrophosphate; FTase; farnesyl transferase; GGPP; geranylgeranyl pyrophosphate; GGTase; geranylgeranyl transferase; Km; a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular targets for altering radiosensitivity: Lessons from Ras as a pre-clinical and clinical model

Keywords: PTI; prenyltransferase inhibitors; FTase; farnesyltransferase; GGTase; Geranylgeranyl transferase; FTI; FTase inhibitor; GGTI; GGTase inhibitor; MAPK; mitogen activated protein kinase; PI3K; phosphatidylinositol 3′-kinase; RTK; receptor tyrosine kinase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه