The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism
Keywords: C6-NBD ceramide; 6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino) hexanoyl) sphingosine; Ac-DEVD-AMC; Ac-Asp-Glu-Val-Asp-aminomethylcoumarin; FCS; fetal calf serum; GCS; glucosylceramide synthase; GlcCer; glucosylceramide; MTT; 3-(4,5-dimethylthiazol-2-yl)