Keywords: AEA; anandamide; BS; behavioral sensitization; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CL; conditioned locomotion; Coc; cocaine; CPP; conditioned place preference; CS+; positive conditioned stimulus; CS-; neutral conditioned st
مقالات ISI (ترجمه نشده)
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Keywords: 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABA; activity-based anorexia; ACC1; acetyl coenzyme-A carboxylase-1; AEA; N-arachidonoylethanolamine; AN; anorexia nervosa; ARC; arcuate nucleus; BBB; blood-brain barrier; BED; binge eating disorder; BN;
Lysophosphatidylcholine and its phosphorothioate analogues potentiate insulin secretion via GPR40 (FFAR1), GPR55 and GPR119 receptors in a different manner
Keywords: Lysophosphatidylcholine (LPC); GPR40 (FFAR1); GPR55; GPR119; Insulin secretion; [Ca2+]i; intracellular calcium ions concentration; cAMP; cyclic AMP; GSIS; glucose-stimulated insulin secretion; GPCR; G protein coupled receptor; IBMX; 3-isobutyl-1-methylxan
Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119
Keywords: GLP-1; glucagon-like peptide-1; GPCR; G protein-coupled receptor; Oleoyl-LPI; Oleoyl-lysophosphatidylinositol; T2D; type 2 diabetes; Lysophosphatidylinositol (LPI); Glucagon-like peptide-1 (GLP-1); GPR119; GPR55; L-cells; Mixed colonic preparation;
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Adipocytes spectrum - From homeostasia to obesity and its associated pathology
Keywords: Acrp30 (AdipoQ); adiponectin gene; AdipoR; adiponectin receptor; AGE; angiotensinogen; ALP; alkaline phosphatase; Ang II; angiotensin II; Angptl2; angiopoietin-like protein-2; Aqp7; aquaporin-7; aP2; adipocyte-specific fatty acid binding protein 2 gene; A
Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists
Keywords: Diabetes; N-methoxyamide derivative; GPR119; Treatment;
Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents
Keywords: Xanthine derivatives; Dual ligands; DPP-IV; GPR119; Merged pharmacophores;
Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity
Keywords: GPR119; Cardiovascular disease; Diabetes; Fatty acids;
Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists
Keywords: GPR119; GDIR; APD597; Diabetes;
Discovery of structurally novel, potent and orally efficacious GPR119 agonists
Keywords: GPCR agonists; GPR119; Pyrazolopyrimidines; Type 2 diabetes
Synthesis and biological evaluation of thienopyrimidine derivatives as GPR119 agonists
Keywords: Diabetes; Thienopyrimidine; GPR119; Treatment;
Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists
Keywords: GPR119; Agonists; Oxadiazole; Constrain; Free fraction;
Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists
Keywords: GPR119; Agonist; Type 2 diabetes;
Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists
Keywords: GPR119; GPCR; Agonist; Type 2 diabetes; Oral glucose tolerance test;
Novel tricyclic pyrazolopyrimidines as potent and selective GPR119 agonists
Keywords: GPCR agonists; GPR119; Tricyclic pyrazolopyrimidines; Type 2 diabetes;
Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists
Keywords: GPR119; Agonist; Type 2 diabetes;
From partial to full agonism: Identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor
Keywords: GPR119; Intrinsic activity; Conformational restriction;
Novel GPR119 agonist AS1669058 potentiates insulin secretion from rat islets and has potent anti-diabetic effects in ICR and diabetic db/db mice
Keywords: Insulin secretion; GPR119; Type 2 diabetes; cAMP; Pancreatic β-cell;
Synthesis and SAR studies of bicyclic amine series GPR119 agonists
Keywords: GPR119; GPR119 agonist; Bicyclic amine; Indanone; Basic nitrogen; oGTT; scGTT
Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile
Keywords: GPR119; GPCR; Diabetes; Lead optimization
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor
Keywords: GPR119; Diabetes; Gauche effect; Configurational entropy; Metabolism
Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice
Keywords: GPR119; G protein-coupled receptor 119; GSIS; glucose-stimulated insulin secretion; T2DM; type 2 diabetes mellitus; SU; sulfonylurea; GPCR; G protein-coupled receptor; GLP-1; glucagon-like peptide-1; HEK; human embryonic kidney; LPC; lysophosphatidylcholi
Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: Predominant localization in pancreatic polypeptide-secreting PP-cells
Keywords: Gpr119; Oleoylethanolamide; Pancreatic polypeptide