Keywords: Succinate; GPR91; Relaxation; Aorta; Endothelium; Prostanoids; Nitric oxide
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition
Keywords: Metformin; Liver fibrosis; Succinate; GPR91;
miR-758 mediates oxLDL-dependent vascular endothelial cell damage by suppressing the succinate receptor SUCNR1
Keywords: oxLDL; oxidized low-density lipoprotein; p-STAT3; phosphorylated STAT3; ROS/RNS; reactive oxygen species and active nitrogen; DLK1; delta-like 1â¯homologue; RTL1; retrotransposon-like 1; DIO3; iodothyronine deiodinase 3; SUCNR1; succinate receptor 1; GPR
Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis
Keywords: AOA; aminooxyacetate; CAC; citric acid cycle; GPCR; G protein-coupled receptors; GPR91; G-protein-coupled receptor 91; HIF-1α; hypoxia-inducible transcription factor-1α; HUVECs; human umbilical vein endothelial cells; LC/MS; liquid chromatography/mass s
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Keywords: GPR91; SUCNR1; Metabolite receptor; GPCR; Drug discovery; Virtual screening; Chemical design;
Succinate, increased in metabolic syndrome, activates GPR91 receptor signaling in urothelial cells
Keywords: Succinate; GPR91; Overactive bladder; Cell culture; Urothelial cells;
Insight into SUCNR1 (GPR91) structure and function
Keywords: SUCNR1; GPR91; Succinate; Ischemia–reperfusion injury; Hypertension; Diabetes(GPCRs), G protein-coupled receptors family; (SUCNR1), succinate receptor 1; (AA), amino acids; (7TM), seven transmembrane domains; (ECLs), extracellular loops; (ICLs), intracell
Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells
Keywords: Succinate; GPR91; Hepatic stellate cell; Nonalcoholic fatty liver disease;
Burst of succinate dehydrogenase and α-ketoglutarate dehydrogenase activity in concert with the expression of genes coding for respiratory chain proteins underlies short-term beneficial physiological stress in mitochondria
Keywords: ACH; acetylcholine; ADR; adrenaline; CBCh; cytobiochemical; CS; citrate synthase; HST; harmful stress; ISC; isocitric acid; MAL; malonate; NBT; nitroblue tetrazolium; OAA; oxaloacetate; PNMT; phenylethanolamine N-methyltransferase; PES; psychoemotional st
Discovery of a potent and selective small molecule hGPR91 antagonist
Keywords: GPR91; Succinate; hGPR91 antagonist; Structure–activity relationship; Pharmacodynamic effect
Succinate is a paracrine signal for liver damage
Keywords: GPR91; Succinate receptor; Stellate cells; Liver; Ischemia; Signal transduction