دانلود مقالات ISI درباره HD، بیماری هانتینگتون + ترجمه فارسی

Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases

Keywords: HD، بیماری هانتینگتون; AD, Alzheimer's Disease; APP, amyloid precursor protein; Aβ, amyloid β peptide; KGDHC, α-ketoglutarate dehydrogenase complex; ETC, electron transport chain; Htt, huntingtin; HD, Huntington's Disease; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3NP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats

Keywords: HD، بیماری هانتینگتون; antioxidant; mitochondrial dysfunction; montelukast; neurotoxicity; oxidative stress3-NP, 3-nitro propionic acid; CMC, carboxy methyl cellulose; CysLTs, cysteinyl leukotrienes; EGTA, ethylene glycol tetraacetic acid; HD, Huntington's disease; HEPES, 4-(2-

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

The transition metals copper and iron in neurodegenerative diseases

Keywords: HD، بیماری هانتینگتون; AD, Alzheimer's disease; PD, Parkinson's disease; HD, Huntington's disease; ALS, amyotrophic lateral sclerosis; ROS, reactive oxygen species; ATP7A, copper-transporting P-type ATPase; TfR, transferrin receptor; DMT1, divalent metal transporter 1; Abeta, a

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

Keywords: HD، بیماری هانتینگتون; HD, Huntington's disease; mPTP, mitochondrial permeability transition pore; CsA, cyclosporin AHuntington disease; Mitochondria; Calcium; Mitochondrial Membrane potential; Permeability transition pore

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular cloning and characterization of the common marmoset huntingtin gene

Keywords: HD، بیماری هانتینگتون; HD, Huntington's disease; Htt, huntingtn; RNAi, RNA interference; cDNA, complementary DNA; PBMC, peripheral blood mononuclear cell; RT, reverse transcription; PCR, polymerase chain reaction; ORF, open reading frame; APP, amyloid precursor protein; GAPDH,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Rule learning, visuospatial function and motor performance in the HdhQ92 knock-in mouse model of Huntington's disease

Keywords: HD، بیماری هانتینگتون; CRF, continuous reinforcement; HD, Huntington's disease; PR, progressive ratioHuntington's disease; Delayed alternation; Progressive ratio; Operant; Taste preference; 9-Hole box; HdhQ92/Q92

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease

Keywords: HD، بیماری هانتینگتون; endocannabinoid; CB1; R6/1 mice; dopamine; GABA; neurodegenerationDAB, 3,3-diaminobenzidine tetrahydrochloride; DNA, Deoxyribonucleic acid; HD, Huntington's disease; i.p., intraperitoneal; LC/MS/MS, liquid chromatography tandem mass spectrometry; MRM, mul

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Partial ablation of mu-opioid receptor rich striosomes produces deficits on a motor-skill learning task

Keywords: HD، بیماری هانتینگتون; mu opioid receptor; striosomes; rotarod; striatum; motor; Huntington's diseaseDS, dermorphin-saporin; HD, Huntington's disease; MOR, mu opioid receptor; SAL1, saline; SAP, saporin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

Keywords: HD، بیماری هانتینگتون; DLST, dihydrolipoyl succinyl transferase; DLD, dihydrolipoamide dehydrogenase; OGDH, α-ketoglutarate dehydrogenase; KGDHC, α-ketoglutarate dehydrogenase complex; AD, Alzheimer's disease; HD, Huntington's disease; PD, Parkinson's disease; 8OH2dG, 8-hydroxy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

The neurobiology of brain and cognitive reserve: Mental and physical activity as modulators of brain disorders

Keywords: HD، بیماری هانتینگتون; AD, Alzheimer's disease; BCR, brain and cognitive reserve; BDNF, brain-derived neurotrophic factor; EE, environmental enrichment; GDNF, glial cell-derived neurotrophic factor; HD, Huntington's disease; VEGF, vascular endothelial growth factorBrain reserve

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Natural and lesion-induced apoptosis in the rat striatum during development

Keywords: HD، بیماری هانتینگتون; ABC, avidin–biotin peroxidase complex; AD, Alzheimer's disease; BDNF, brain-derived neurotrophic factor; E, embryonic day; GABA, γ-aminobutyric acid; HD, Huntington's disease; ir, immunoreactive; MSNs, medium spiny neurons; NGS, normal goat serum; NT-3, n

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Prediction of deleterious non-synonymous single nucleotide polymorphisms of genes related to ethanol-induced toxicity

Keywords: HD، بیماری هانتینگتون; BH4, tetrahydrobiopterin; EGF, epidermal growth factor; GABA, γ-aminobutyric acid; GABRA2, GABAA2 receptor; GCH1GTP, cyclohydrolase 1; HD, Huntington's disease; MAPK, mitogen-activated protein kinase; NO, nitric oxide; nsSNP, non-synonymous single nucleot

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: Involvement of phospholipaseCγ activity and glutamate receptor expression

Keywords: HD، بیماری هانتینگتون; NMDA receptor; hippocampus; learning; neurotrophin; plasticity; R6/1 miceaCSF, artificial cerebrospinal fluid; BDNF, brain-derived neurotrophic factor; fEPSP, field excitatory postsynaptic potential; HD, Huntington's disease; HFS, high-frequency condition

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

Findings of preserved implicit attention in methamphetamine dependent subjects

Keywords: HD، بیماری هانتینگتون; AD, Alzhemier's Disease; ANOVA, analysis of variance; AR, attend-repetition; IR, ignore repetition; MA, methamphetamine; ms, milliseconds; NART, National Adult Reading Test; NEU, neutral; HD, Huntington's Disease; RTs, reaction times; SCID, Structured Cli

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid

Keywords: HD، بیماری هانتینگتون; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; BSA, bovine serum albumin; CDK, cyclin-dependent kinase; CyD1, cyclin D1; CyE, cyclin E; HD, Huntington's disease; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; PV

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats

Keywords: HD، بیماری هانتینگتون; GABA, γ-aminobutyric acid; GSH, reduced glutathione; HD, Huntington's disease; MDH, malondialdehyde; 3-NP, 3-nitropropionic acid; SDH, succinate dehydrogenase; TGB, tiagabine.Biochemical parameters; Behavioral parameters; Huntington's disease; 3-nitroprop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease

Keywords: HD، بیماری هانتینگتون; HD, Huntington's Disease; HTT, human Huntington's disease gene; htt, huntingtin; CREB, cAMP response element-binding protein; Sp1, specificity protein 1; CBP, CREB-binding protein; TBP, TATA binding box protein; COUP-TF, chicken ovalbumin upstream promote

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Golgi apparatus and neurodegenerative diseases

Keywords: HD، بیماری هانتینگتون; GA, Golgi apparatus; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; CJD, Creutzfeldt-Jacob disease; MSA, multiple system atrophy; PD, Parkinson's disease; SCA2, spinocerebelar ataxia type 2; NPC, Niemann-Pick type C; HD, Huntington's disease

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity

Keywords: HD، بیماری هانتینگتون; 3-NP, 3-nitropropionic acid; TNF-alpha, tissue necrosis factor-alpha; ATP, adenosine triphosphate; NMDA, N-methyl-d-aspartate; HD, Huntington's disease; MPTP, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; HPLC, high performance liquid chromatography; MDA,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

The effect of feedback on non-motor probabilistic classification learning in Parkinson's disease

Keywords: HD، بیماری هانتینگتون; BDI, Beck Depression Inventory; BG, basal ganglia; DA, dopamine; FB, feedback; HD, Huntington's disease; H&Y, Hoehn & Yahr; MMSE, Mini Mental State Examination; MTL, medial temporal lobe; NART, National Adult Reading Test; PA, paired associate; PD, Parkin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

Keywords: HD، بیماری هانتینگتون; climbing; running wheel; psychiatric; atrophy; gliosis; DARPP-32DARPP-32, dopamine and cyclic AMP-regulated phosphoprotein with molecular weight 32 kDa; GFAP, glial fibrillary acidic protein; HD, Huntington's disease; KI, knock-in; PBS, phosphate-buffered

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

Role of mTOR in physiology and pathology of the nervous system

Keywords: HD، بیماری هانتینگتون; Aβ, β-amyloid; AD, Alzheimer's disease; BDNF, brain-derived neurotrophic factor; HD, Huntington's disease; CD, cortical displasia; 4E-BP1, eIF-4E binding protein; KO, knockout; NF1, type I neurofibromatosis; p70S6K, p70 ribosomal S6 kinase; PD, Parkinson'

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease

Keywords: HD، بیماری هانتینگتون; HD, Huntington's Disease; UHDRS, Unified Huntington's Disease Rating Scale; MRI, Magnetic Resonance Imaging; fMRI, functional Magnetic Resonance Imaging; DTI, Diffusion Tensor Imaging; DWI, Diffusion Weighted Imaging; CAG, cytosine–adenine–guanine; WM, wh

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner

Keywords: HD، بیماری هانتینگتون; FEN1, Flap endonuclease 1; Rad, Radiation sensitive; HD, Huntington's disease; DM1, Myotonic dystrophy type 1; SDS, Sodium dodecyl sulfate; PAGE, Polyacrylamide gel electrophoresis; MAT, Mating type locus; YAC, Yeast artificial chromosome; SCA, Spinocereb

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Time-related changes in constitutive and inducible nitric oxide synthases in the rat striatum in a model of Huntington's disease

Keywords: HD، بیماری هانتینگتون; cNOS, constitutive nitric oxide synthase; eNOS, endothelial nitric oxide synthase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HD, Huntington's disease; iNOS, inducible nitric oxide synthase; nNOS, neuronal nitric oxide synthase; NO, nitric oxide; NM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Drug targeting of dysregulated transcription in Huntington's disease

Keywords: HD، بیماری هانتینگتون; HD, Huntington's Disease; Htt, Huntingtin; IND, Investigational New Drug; HAT, Histone Acetyl Transferase; HDAC, Histone deacetylase; SAHA, Suberoylanilide hydroxamic acid; Sir2, Silent Information Regulator (Sirtuin); SirT1, Sirtuin 1; SirT2, Sirtuin 2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Glycolipid and ganglioside metabolism imbalances in Huntington's disease

Keywords: HD، بیماری هانتینگتون; 2,3-SPG, 2,3-sialosylparagloboside; B2M, β-2-microglobulin; CBP, carbohydrate binding protein; Ct, threshold cycle; GalNAc, N-acetylgalactosamine; HD, Huntington's disease; HPRT, hypoxanthine guanine phosphoribosyl transferase; LD1, 9-O-acetyl disialolact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease

Keywords: HD، بیماری هانتینگتون; APC, adenomatous polyposis coli; GPCR, G protein-coupled receptor; HD, Huntington's disease; DRPLA, dentato and rubral pallidoluysian atrophy; SBMA, spinal and bulbar muscular atrophy; SCA, spinocerebellar ataxia; HPRT, hypoxanthine phosphoribosyl transfe

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

The corticostriatal pathway in Huntington's disease

Keywords: HD، بیماری هانتینگتون; HD, Huntington's disease; CAG, (cytosine adenine guanine) DNA triplet sequence coding for glutamine; YAC, yeast artificial chromosome; Tg, transgenic; MSSN, medium-sized spiny neuron; NMDA, N-methyl-d-aspartate; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazol

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2007 سفارش ترجمه

Cholesterol dysfunction in neurodegenerative diseases: Is Huntington's disease in the list?

Keywords: HD، بیماری هانتینگتون; CNS, central nervous system; HD, Huntington's disease; 24-OH-Chol, 24S-hydroxycholesterol; ApoE, apolipoprotein E; SLOS, Smith–Lemli–Opitz syndrome; AD, Alzheimer's disease; Aβ, beta-amyloid; NPC, Niemann–Pick disease; HIP14, huntingtin interacting protei

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Modulating apoptosis as a target for effective therapy

Keywords: HD، بیماری هانتینگتون; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; DR, death receptor; HD, Huntington's disease; IAPs, inhibitor of apoptosis proteins; IDDM, insulin-dependent diabetes mellitus; ND, neurodegenerative diseases; NODm, non-obese diabetic mice; PD,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه