Keywords: AIPC; Androgen-independent prostate cancer; AKAP1; cAMP signaling; AML; acute myeloid leukemia; BAK; Bcl-2 homologous antagonist killer; BAX; Bcl-2-associated X protein; BCL-2; B-cell lymphoma 2; BMRP; BCL-2 interacting mitochondrial ribosomal protein; C7
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy
Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac
Original ResearchA phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours
Keywords: De-differentiated liposarcoma; HDM2; MDM2; p53; Pharmacokinetics; Pharmacodynamics; SAR405838; Solid tumours;
Variant of BCL3 gene is strongly associated with five-year survival of non-small-cell lung cancer patients
Keywords: BCL3; B-cell CLL/lymphoma 3; NSCLC; non-small-cell lung cancer; RelA; v-rel avian reticuloendotheliosis viral oncogene homolog A; RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; c-Rel; v-rel avian reticuloendotheliosis viral oncogene hom
Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1α stabilization/nuclear translocation in bone metastasis from breast carcinoma
Keywords: EMT; epithelial-mesenchymal transition; MET; mesenchymal-epithelial transition; HIF-1; hypoxia inducible factor-1; TAZ; transcriptional co-activator with PDZ-binding motif; YAP; Yes-associated protein; Wwox; WW-domain containing oxidoreductase; MDM2;
Substituted piperidines as HDM2 inhibitors
Keywords: HDM2; MDM2; p53; Substituted piperidine; Small molecule inhibitor; Cancer; Oncology;
Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization
Keywords: Human herpesvirus-6B; p53; U19; Virus-cell interactions; HDM2;
Inhibitors of the p53/hdm2 protein-protein interaction-path to the clinic
Keywords: p53; hdm2; hdmx; Protein-protein interaction; Anticancer agent;
BCL11B tumor suppressor inhibits HDM2 expression in a p53-dependent manner
Keywords: BCL11B; HDM2; p53; p53-HDM2 feedback loop; Tumor suppressor;
Long isoform of ErbB3 binding protein, p48, mediates protein kinase B/Akt-dependent HDM2 stabilization and nuclear localization
Keywords: Akt; ErbB3 binding protein (Ebp1); HDM2; Oncogene;
Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway
Keywords: Phospholipase D; mTOR; HDM2; Serum- and glucocorticoid-induced kinase 1
Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system
Keywords: Hdm2; Hdmx; Protein-protein interactions; Genetic selection; Cyclic peptides;
HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma
Keywords: Neuroblastoma; HDM2; p53; p73; Noxa; Apoptosis
West Nile virus capsid protein interaction with importin and HDM2 protein is regulated by protein kinase C-mediated phosphorylation
Keywords: Apoptosis; Capsid; HDM2; Importin; Phosphorylation; PKC
Stereochemical studies of hexylitaconic acid, an inhibitor of p53–HDM2 interaction
Keywords: VCD; Enantiomers; p53; HDM2; Enantioseparation; α-Alkyl carboxylic acid
A low dose pre-irradiation induces radio- and heat-resistance via HDM2 and NO radicals, and is associated with p53 functioning
Keywords: p53; HDM2; NO; Radio-resistance; Heat-resistance;
β-Peptides with improved affinity for hDM2 and hDMX
Keywords: Protein–protein interactions; β-Peptides; Peptidomimetics; Inhibitors; Foldamer; p53; hDM2; Cancer
N-Acylpolyamine inhibitors of HDM2 and HDMX binding to p53
Keywords: HDMX; HDM2; Cancer; Protein-protein interactions;
Hdm2 and Nitric Oxide Radicals Contribute to the P53-Dependent Radioadaptive Response
Keywords: Radiobiology; p53; Hdm2; NO; Radioadaptive response;
Detection of HDM2 and VEGF co-expression in cancer cell lines: novel effect of HDM2 antisense treatment on VEGF expression
Keywords: HDM2; VEGF; Co-expression; Antisense oligonucleotide; Cancer
Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design
Keywords: HDM2; p53; Protein–protein interaction; HDM2 antagonist; Pharmacokinetic; Structure-based drug design
Enantiomerically pure 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists
Keywords: Hdm2; Protein–protein interaction; p53
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity
Keywords: Hdm2; p53; Benzodiazepinedione
(R)-Roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosis
Keywords: (R)-Roscovitine; CYC202; Seliciclib; Nutlin-3; Apoptosis; p53; HDM2; Cyclin; Cyclin-dependent kinase; Cancer
Expression of cyclooxygenase-2 in colorectal adenocarcinoma is associated with p53 accumulation and hdm2 overexpression
Keywords: COX-2; p53; HDM2; Colorectal adenocarcinoma
Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B
Keywords: S100B; Calcium-binding protein; S100 protein; p53; Hdm2; Mdm2
HDM2 negatively affects the Chk2-mediated phosphorylation of p53
Keywords: Chk2; p53; HDM2; Protein kinase; Phosphorylation
1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2-p53 interaction: discovery and SAR
Keywords: 1,4-Benzodiazepine-2,5-diones; p53; HDM2; Thermofluor; Fluorescence polarization peptide displacement assay; p53-HDM2 interaction;
Activated Akt expression in breast cancer: Correlation with p53, Hdm2 and patient outcome
Keywords: HER-2; Hdm2; Immunohistochemistry; p53; Phospho-Akt;