Scube activity is necessary for Hedgehog signal transduction in vivo
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Zebrafish; Muscle development
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Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis
Keywords: سیگنالینگ جادوگر; Primary cilia; Hedgehog signaling; Gli3; Osteoarthritis; Cartilage; Chondrocyte;
Adrenocortical stem and progenitor cells: Implications for adrenocortical carcinoma
Keywords: سیگنالینگ جادوگر; ACC, adrenocortical carcinoma; ACA, adrenocortical adenoma; ACT, adrenocortical tumor; FAdE, fetal adrenal enhancerStem cell; Adrenocortical carcinoma; Sf1; Hedgehog signaling; β-catenin; IGF2
Ligand-independent activation of the Hedgehog pathway displays non-cell autonomous proliferation during eye development in Drosophila
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Costal-2; Patched; Non-cell autonomous overgrowth;
Hh signaling regulates patterning and morphogenesis of the pharyngeal arch-derived skeleton
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Neural crest; Endoderm; Zebrafish; Morphogenesis
The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis
Keywords: سیگنالینگ جادوگر; IFT; intraflagellar transport; BBS; Bardet-Biedl syndrome; JATD; Jeune asphyxiating thoracic dystrophy; SRPIII; short rib polydactyly type III; ALP; alkaline phosphatase; BMP; bone morphogenetic protein; RUNX2; Runt-related transcription factor 2; OCN;
Hedgehog signaling displays a biphasic expression pattern during intestinal injury and repair
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Gastrointestinal injury; Small intestinal epithelium
Prevailing importance of the hedgehog signaling pathway and the potential for treatment advancement in sarcoma
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Sarcoma; Smoothened; Patched; Chondrosarcoma; Vismodegib
Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors
Keywords: سیگنالینگ جادوگر; Cyclopamine; Steroidal alkaloid; Cancer chemotherapy; Hedgehog signaling; Structure-activity relationships;
Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
Keywords: سیگنالینگ جادوگر; GLI3; Hedgehog signaling; Classical Hodgkin lymphoma; Immunohistochemistry
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened
Keywords: سیگنالینگ جادوگر; SmoM2; Ductal hyperplasia; Paracrine tissue interactions; Hedgehog signaling; Microenvironment; Notch signaling
Endothelin-2 is upregulated in basal cell carcinoma under control of Hedgehog signaling pathway
Keywords: سیگنالینگ جادوگر; Basal cell carcinoma; Endothelin-2; Hedgehog signaling;
Hedgehog signaling and gastrointestinal cancer
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Gastric epithelium; Intestine; Colon cancer; Gastric cancer; Gastrointestinal development;
Regulation of Smoothened by Drosophila G-protein-coupled receptor kinases
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; G-protein-coupled receptor kinase; Protein trafficking; Patched; Smoothened; Drosophila melanogaster;
Indian Hedgehog Regulates Intestinal Stem Cell Fate Through Epithelial−Mesenchymal Interactions During Development
Keywords: سیگنالینگ جادوگر; Hedgehog Signaling; ECM; MMP; BMPBMP, bone morphogenetic protein; ECM, extracellular matrix; Hh, hedgehog; Hhip, Hedgehog interacting protein; Ihh, Indian Hedgehog; ISC, intestinal stem cell; ISEMF, intestinal subepithelial myofibroblast; MMP, matrix meta
Modulators of the hedgehog signaling pathway
Keywords: سیگنالینگ جادوگر; Antitumor agents; Cyclopamine; Hedgehog signaling; AKT; protein kinase B; ALP; alkaline phosphatase; BCC; basal cell carcinoma; BCR-ABL1; breakpoint cluster region-Abelson murine leukemia; β-TrCP; β-transducin repeat containing protein; BMP; bone morpho
The long road to colorectal cancer therapy: Searching for the right signals
Keywords: سیگنالینگ جادوگر; Colorectal cancer; Signaling pathways; Biomarkers; Monoclonal antibodies; Tyrosine kinase inhibitors; IGF-1R; c-MET; Wnt signaling; Hedgehog signaling; Src family
UDP xylose synthase 1 is required for morphogenesis and histogenesis of the craniofacial skeleton
Keywords: سیگنالینگ جادوگر; Extracellular matrix; Zebrafish; Skeletogenesis; Cartilage; Perichondrium; Glycosaminoglycans; Heparan sulfate; Chondroitin sulfate; Proteoglycans; Hedgehog signaling; Neural crest; UDP-xylose synthase; FGF signaling
Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Pancreatic cancer; Mechanism; Anticancer treatment; Cyclopamine
Trafficking, development and hedgehog
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Trafficking; Rab23; Cilia; Intraflagellar transport; Patched; Smoothened; Gli; Sterols
Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Fetal liver; Hepatoblast
The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Drosophila development; Cubitus interruptus; Gli proteins; Parafibromin; Hyrax
Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent
Keywords: سیگنالینگ جادوگر; Primordial germ cell; Zebrafish; Hedgehog signaling; Smoothened; Cyclopamine;
Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer
Keywords: سیگنالینگ جادوگر; PSA; Cyclopamine; Prodrug; Hedgehog signaling; Peptides
Hedgehog Signalling in Androgen Independent Prostate Cancer
Keywords: سیگنالینگ جادوگر; Androgen-independent prostate cancer; Circulating tumour cells; Cyclopamine; Hedgehog signaling; LNCaP; PTCH
Crosstalk of hedgehog and Wnt pathways in gastric cancer
Keywords: سیگنالینگ جادوگر; Gastric cancer; Hedgehog signaling; Wnt signaling; Gli1; β-catenin
Hedgehog Signaling Pathway and Lung Cancer
Keywords: سیگنالینگ جادوگر; Hedgehog signaling; Lung cancer
Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3
Keywords: سیگنالینگ جادوگر; Ptchd3; Hedgehog signaling; Patched; Male germ cell-specific; Sperm; Midpiece
Novel Hedgehog pathway targets against basal cell carcinoma
Keywords: سیگنالینگ جادوگر; Skin cancer; Hedgehog signaling; Chemoprevention; Statins; Vitamin D; UV light; Ptch; Basal cell carcinoma
Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms
Keywords: سیگنالینگ جادوگر; Kinesin; Skeletal patterning; Hedgehog signaling; Intraflagellar transport
Discontinuous organization and specification of the lateral floor plate in zebrafish
Keywords: سیگنالینگ جادوگر; Neural patterning; Floor plate formation; Hedgehog signaling; Nkx2.2; Homeobox genes
Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened
Keywords: سیگنالینگ جادوگر; Clathrin; Endosomes; Hedgehog signaling; Patched; Skeletal muscle; Smoothened; Zebrafish
Wnt Signaling in Stem Cells and Non-Small-Cell Lung Cancer
Keywords: سیگنالینگ جادوگر; APC gene; β-catenin; Carcinogenesis; Disheveled proteins; Hedgehog signaling;
The ESC-E(Z) complex participates in the hedgehog signaling pathway
Keywords: سیگنالینگ جادوگر; Cellular memory; Epigenetics; Polycomb group; Enhancer of zeste; Extra sex combs; Knock-down; Cyclopia; hedgehog signaling; Histone methylation; Medaka;
Hedgehog signaling and cell cycle control in differentiating erythroid progenitors
Keywords: سیگنالینگ جادوگر; Cell cycle; Erythroid differentiation; Hedgehog signaling; CD34; CD36; Hemoglobinization;
Hedgehog signaling regulates expansion of pancreatic epithelial cells
Keywords: سیگنالینگ جادوگر; Pancreas; Islets; Hedgehog signaling; Pax4 promoter; ngn3;