Keywords: HGF، عامل رشد هپاتوسیت; bFGF, basic fibroblast growth factor; CdM, conditioned medium; EGF, epidermal growth factor; ELISA, enzyme-linked immunosorbent assay; GFP, green fluorescent protein; HGF, hepatocyte growth factor; LVESP, left ventricle end systolic pressure; LVEDP, left
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Keywords: HGF، عامل رشد هپاتوسیت; α-SMA, alpha-smooth muscle actin; Tgfbr2, transforming growth factor –beta receptor 2; HGF, hepatocyte growth factor; ER, estrogen receptor; Her2, human epidermal growth factor receptor 2; CAF, carcinoma-associated fibroblast; HIF-1α, hypoxia inducible fa
Keywords: HGF، عامل رشد هپاتوسیت; Hypoxia-Inducible Factors; Liver Fibrosis; Kupffer Cells; Hepatic Stellate CellsBDL, bile duct ligation; CCl4, carbon tetrachloride; Ccr, C-C chemokine receptor; FGF, fibroblast growth factor; HGF, hepatocyte growth factor; HIFs, hypoxia-inducible factors
Keywords: HGF، عامل رشد هپاتوسیت; Liver; Hepatocyte; Tissue; Multi-scale; ModelingVLN, Virtual Liver Network; SOP, standard operating procedure; HGF, hepatocyte growth factor; PI3K, phosphatidylinositol 3 kinase; ODE, ordinary differential equation; IL1, interleukin 1; IL6, interleukin 6;
Keywords: HGF، عامل رشد هپاتوسیت; Abcg5, ATP-binding cassette transporters G5; BAs, bile acids; GI, gastrointestinal tract; LPS, lipopolysaccharide; PHx, partial hepatectomy; HGF, hepatocyte growth factor; NKT, natural kill T; IL, interleukin; I/R, ischemia/reperfusion; TGR5, G protein-co
Keywords: HGF، عامل رشد هپاتوسیت; DNA, deoxyribonucleic acid; EGF, epidermal growth factor; ERK1/2, extracellular signal-related kinase 1 and 2; FAH, fumarylacetoacetate hydrolase; FGF, fibroblast growth factor; HBEGF, heparin-binding EGF-like growth factor; HGF, hepatocyte growth factor;
Keywords: HGF، عامل رشد هپاتوسیت; CS, chitosan; DMSO, dimethyl sulfoxide; ECM, extracellular matrix; FBS, fetal bovine serum; HGF, hepatocyte growth factor; IGF, insulin like growth factor; MEM, minimum essential medium; PBS, phosphate buffered saline; PCL, polycaprolactone; PDGF, platele
Construction of a multicolor GeneScan analytical system to detect clonal rearrangements of immunoglobulin and T cell receptor genes in canine lymphoid tumors
Keywords: HGF، عامل رشد هپاتوسیت; GeneScan; Dog; lympHoma; Multicolor; PCRFNA, fine-needle aspirate; HGF, hepatocyte growth factor; IgH, immunoglobulin heavy chain; J region, joining region; TCRγ, T cell receptor γ-chain; V region, variable region
Blocking c-Met signaling enhances bone morphogenetic protein-2-induced osteoblast differentiation
Keywords: HGF، عامل رشد هپاتوسیت; ALP, alkaline phosphatase; BMP, bone morphogenetic protein; ERK, extracellular signal-regulated kinase; HGF, hepatocyte growth factor; MAPK, mitogen-activated protein kinase; MEK, MAPK/ERK kinase; PI3K, phosphatidylinositol-3-kinase; RA, rheumatoid arthri
Pazopanib as Third Line Therapy for Metastatic Renal Cell Carcinoma: Clinical Efficacy and Temporal Analysis of Cytokine Profile
Keywords: HGF، عامل رشد هپاتوسیت; kidney neoplasms; cytokines; pazopanib; biological markers; mortalityCFSE, carboxyfluorescein succinimidyl ester; CR, complete response; DOT2, therapy duration in second line setting; HGF, hepatocyte growth factor; IL, interleukin; mRCC, metastatic renal
VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner
Keywords: HGF، عامل رشد هپاتوسیت; GBM, glioblastoma; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; TGFβ, transforming growth factor beta; TGFβR, transforming growth factor beta receptor; HGF, hepatocyte growth factor; MET, mesenchymal epithe
MSP: An emerging player in metabolic syndrome
Keywords: HGF، عامل رشد هپاتوسیت; MSP, macrophage stimulating protein; HGF, hepatocyte growth factor; HGFL, hepatocyte growth like factor; NGF-γ, nerve growth factor-γ; EGF-BP, epidermal growth factor-binding protein; HGFA, hepatocyte growth factor activator; HAT, human airway trypsin-lik
Dynamic reciprocity in cell–scaffold interactions
Keywords: HGF، عامل رشد هپاتوسیت; ABM, acellular bladder matrix; ECM, extracellular matrix; ESC, embryonic stem cells; FGF2, fibroblast growth factor-2; HA, hyaluronic acid; HGF, hepatocyte growth factor; IGF-1, insulin-like growth factor-1; iPSC, induced pluripotent stem cells; MMP, matr
Targeting the Pro-Survival Protein MET with Tivantinib (ARQ 197) Inhibits Growth of Multiple Myeloma Cells 12
Keywords: HGF، عامل رشد هپاتوسیت; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK-3β, glycogen synthase kinase-3; HGF, hepatocyte growth factor; IC50, half maximal inhibitory concentration; MAPK, mitogen-activated protein kinase; MET, MNNG HOS transforming gene; MM, multiple myeloma;
Combined hypoxia inducible factor-1α and homogeneous endothelial progenitor cell therapy attenuates shunt flow–induced pulmonary arterial hypertension in rabbits
Keywords: HGF، عامل رشد هپاتوسیت; Congenital heart disease; pulmonary arterial hypertension; HIF-1α; endothelial progenitor cells; rabbitsEPC, endothelial progenitor cell; HGF, hepatocyte growth factor; HIF-1, hypoxia inducible factor-1; hHIF-1, human hypoxia inducible factor-1; PAH, pulm
Biomatrices for bladder reconstruction
Keywords: HGF، عامل رشد هپاتوسیت; AM, amniotic membrane; ADSC, adipose-derived stem cell; BM, bone marrow; BAM, bladder acellular matrix; bFGF, basic fibroblast growth factor; Ch, chitosan; ECM, extracellular matrix; EGF, epidermal growth factor; HGF, hepatocyte growth factor; GAG, glycos
SOMCL-863, a novel, selective and orally bioavailable small-molecule c-Met inhibitor, exhibits antitumor activity both in vitro and in vivo
Keywords: HGF، عامل رشد هپاتوسیت; HGF, hepatocyte growth factor; HUVEC, human umbilical vein endothelial cells; MVD, microvessel densityc-Met; SOMCL-863; Receptor tyrosine kinase; Cancer; Angiogenesis
Downregulation of hepatic stimulator substance during the early phase of liver regeneration inhibits E-cadherin expression in mice
Keywords: HGF، عامل رشد هپاتوسیت; ALR, augmenter of liver regeneration; AP, activator protein; C/EBP, CCAAT/enhancer-binding protein; ChIP, chromatin immunoprecipitation; EGF, epidermal growth factor; GFER, growth factor erv1; HGF, hepatocyte growth factor; HSS, hepatic stimulator substan
Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility
Keywords: HGF، عامل رشد هپاتوسیت; MTP, matriptase; NS/P, neural stem/progenitor; HGF, hepatocyte growth factor; PI3K, phosphatidylinositol-3-kinase; Akt, protein kinase BNeural stem cell; Migration; Hepatocyte growth factor; Transmembrane serine protease; Protein kinase signaling
Ethanolic extract of sharah, Plectranthus aegyptiacus, enhances healing of skin wound in rats
Keywords: HGF، عامل رشد هپاتوسیت; cDNA, complementary deoxyribonucleic acid; DEPC, diethyl pyrocarbonate; DNA, deoxyribonucleic acid; EGT, early granulation tissue; GT, granulation tissue; HGF, hepatocyte growth factor; c-Met, HGF-receptor; KX, ketamine–xylazine; M-MuLV, Moloney Murine Le
The role of microRNAs in melanoma
Keywords: HGF، عامل رشد هپاتوسیت; EZH2, enhancer of zeste homolog 2; HGF, hepatocyte growth factor; MITF, microphthalmia-associated transcription factor; NHEM, normal human epidermal melanocyte; YB1, Y box binding protein 1Melanoma; MicroRNA; Expression profiling; Target identification; B
Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor
Keywords: HGF، عامل رشد هپاتوسیت; α-SMA, α-smooth muscle actin; CAF, cancer-associated fibroblasts; 2D, two-dimensional; 3D, three-dimensional; ECM, extracellular matrix; EMT, epithelial–mesenchymal transition; HDF, natal human dermal fibroblast; HGF, hepatocyte growth factor; TGF-β, tran
Miniaturized pre-clinical cancer models as research and diagnostic tools
Keywords: HGF، عامل رشد هپاتوسیت; μCCA, microscale cell culture analog; CAM-DR, cell-adhesion mediated drug resistance; CTCs, circulating tumor cells; ECM, extracellular matrix; HGF, hepatocyte growth factor; Hh, Hedgehog; MSCs, mesenchymal stem cells; VEGF, vascular endothelial cells gro
Insulin infusion reduces hepatocyte growth factor in lean humans
Keywords: HGF، عامل رشد هپاتوسیت; ALT, alanine aminotransferase; CRP, C-reactive protein; GGT, γ-glutamyl transpeptidase; HGF, hepatocyte growth factor; WHR, waist to hip ratioObesity; Adipose tissue; Hyperinsulinemic–euglycemic clamp
EMT–MET in renal disease: Should we curb our enthusiasm?
Keywords: HGF، عامل رشد هپاتوسیت; α-SMA, alpha smooth muscle actin; Alk3, activin-like kinase 3, a BMP receptor; BMP, bone morphogenetic protein; EMT, epithelial–mesenchymal transition; FSP1, fibroblast specific protein 1; HGF, hepatocyte growth factor; HSP72, heat shock protein; Ilk, int
PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation
Keywords: HGF، عامل رشد هپاتوسیت; c-Cbl; Oncoprotein; Phosphorylation; Proteasomal degradation; PTK6; UbiquitinBrk, breast tumor kinase; EGF, epidermal growth factor; HGF, hepatocyte growth factor; PDGF, platelet-derived growth factor; PR, proline-rich; PTK, protein tyrosine kinase; RTK,
Met/HGF receptor activation is regulated by juxtamembrane Ser985 phosphorylation in hepatocytes
Keywords: HGF، عامل رشد هپاتوسیت; ALS, amyotrophic lateral sclerosis; BrdU, 5-bromo-2′-deoxyuridine; HGF, hepatocyte growth factor; MDC, monodansylcadaverine; PP2A, protein phosphatase 2A; RTK, receptor tyrosine kinase; TPA, 12-O-tetradecanoylphorbol-13-acetateGrowth factor; Liver injury;
The effect of pre-storage whole-blood leukocyte reduction on cytokines/chemokines levels in autologous CPDA-1 whole blood
Keywords: HGF، عامل رشد هپاتوسیت; AB, autologous blood; CPDA-1, citrate-phosphate-dextrose-adenine-1; EGF, Epidermal growth factor; b-FGF, basic fibroblast growth factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; HGF, hepatocyte growth factor; IFN, interferon; IL, interleu
Comparative analysis of gene expression profiles of acute hepatic failure and that of liver regeneration in rat
Keywords: HGF، عامل رشد هپاتوسیت; A, absent; AHF, acute hepatic failure; CCl4, carbon tetrachloride; HGF, hepatocyte growth factor; LR, liver regeneration; M, marginal; NC, normal control; P, present; PH, partial hepatectomy; RT-PCR, real-time polymerase chain reaction; SD, Sprague–Dawley
Recombinant human hepatocyte growth factor transfection alleviates hyperkinetic pulmonary artery hypertension in rabbit models
Keywords: HGF، عامل رشد هپاتوسیت; 9; 11; 18; 39Ad-hHGF, adenovirus coding with human hepatocyte growth factor; Ad-Null, adenovirus without hepatocyte growth factor gene; HGF, hepatocyte growth factor; LV, left ventricle; mPAP, mean pulmonary artery pressure; PAH, pulmonary artery hyperten
Biology and Clinical Applications of Pancreatic Cancer Stem Cells
Keywords: HGF، عامل رشد هپاتوسیت; Pancreatic Cancer Stem Cells; Tumor Microenvironment; Drug ResistanceALDH1, aldehyde dehydrogenase 1; CSC, cancer stem cells; EMT, epithelial–mesenchymal transition; HGF, hepatocyte growth factor; PDAC, pancreatic ductal adenocarcinoma; PCSC, pancreatic c
Higher fetuin-A, lower adiponectin and free leptin levels mediate effects of excess body weight on insulin resistance and risk for myelodysplastic syndrome
Keywords: HGF، عامل رشد هپاتوسیت; AML, Acute Myeloid Leukemia; BMI, Body Mass Index; BM, bone marrow; CMML, chronic myelomonocytic leukemia; FAB, French American British Classification; FLI, free leptin index; HGF, hepatocyte growth factor; IL-6, interleukin-6; IPSS, International Prognos
PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2
Keywords: HGF، عامل رشد هپاتوسیت; HCC, hepatocellular carcinoma cell; HGF, hepatocyte growth factor; ERK, extracellular signal-regulated kinases; PKC, protein kinase C; BIM, Bisindolymaleimide; EMT, epithelial mesenchymal transition; ConA, Concanavalin AERK; Paxillin; Rac; PKC; HGF; c-Met
Allogeneic Cardiospheres Safely Boost Cardiac Function and Attenuate Adverse Remodeling After Myocardial Infarction in Immunologically Mismatched Rat Strains
Keywords: HGF، عامل رشد هپاتوسیت; allogeneic cardiospheres; high therapeutic potential; safe administrationCDC, cardiosphere-derived cell; DNA, deoxyribonucleic acid; HGF, hepatocyte growth factor; IFN, interferon; IGF, insulin-like growth factor; IL, interleukin; LV, left ventricular; LV
The Gastrointestinal Tumor Microenvironment
Keywords: HGF، عامل رشد هپاتوسیت; CAC, colitis-associated cancer; CAF, cancer-associated fibroblast; CRC, colorectal cancer; CSC, colorectal cancer stem cell; DC, dendritic cell; EMT, epithelial-mesenchymal transition; GI, gastrointestinal; HGF, hepatocyte growth factor; IFN, interferon;
Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
Keywords: HGF، عامل رشد هپاتوسیت; Liver Cancer; Extracellular Matrix; Angiogenesis; ChemopreventionCSC, cancer stem cell; EC, endothelial cell; ECM, extracellular matrix; EGF, epidermal growth factor; FGF, fibroblast growth factor; HGF, hepatocyte growth factor; HIF-1, hypoxia-inducible f
Microenvironment and tumor cell plasticity: An easy way out
Keywords: HGF، عامل رشد هپاتوسیت; CA, carbonic anhydrases; CAFs, cancer-associated fibroblasts; ECM, extracellular matrix; EMT, epithelial–mesenchymal transition; EPC, endothelial precursor cell; HGF, hepatocyte growth factor; HIF-1, hypoxia-inducible factor-1; Keap-1, kelch-like ECH-asso
Recent preclinical evidence advancing cell therapy for Alzheimer's disease
Keywords: HGF، عامل رشد هپاتوسیت; AD, Alzheimer's disease; APP, amyloid precursor protein; BDNF, brain-derived neurotrophic factor; CD, cDNA; HGF, hepatocyte growth factor; NGF, neural growth factor; NSC, neural stem cell; SCF, stem cell factor; SDF-1, stromal cell-derived factor-1; VEGF,
Co-expression of hepatocyte growth factor and c-met in epithelial odontogenic tumors
Keywords: HGF، عامل رشد هپاتوسیت; AOT, adenomatoid odontogenic tumor; CCOT, calcifying cystic odontogenic tumor; DAB, diaminobenzidine; HGF, hepatocyte growth factor; KCOT, keratocystic odontogenic tumor; NK4, N-domain and kringle 4; PBS, phosphate buffered saline; TSLC1, tumor suppressor
Multikinase inhibitor sorafenib transiently promotes necrosis after radiofrequency ablation in rat liver but activates growth signals
Keywords: HGF، عامل رشد هپاتوسیت; RFA, radiofrequency ablation; HCC, hepatocellular carcinoma; HGF, hepatocyte growth factor; EGF, epidermal growth factor; VEGF, vascular endothelial growth factor; DAPI, 4′,6-diamidin-2′-phenylindoldihydrochloridRadiofrequency ablation; Sorafenib; Tissue
Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation
Keywords: HGF، عامل رشد هپاتوسیت; FTY720; Osteoblast; Rheumatoid arthritis; Sphingosine 1-phosphateALP, alkaline phosphatase; BMP, bone morphogenic protein; ERK, extracellular signal-regulated kinase; HGF, hepatocyte growth factor; MAPK, mitogen-activated protein kinase; MEK, MAPK/ERK kin
Serotonin: A double-edged sword for the liver?
Keywords: HGF، عامل رشد هپاتوسیت; Serotonin; Liver; Liver regeneration; Liver diseases5-HT, 5-hydroxytryptamine = serotonin; 5-HTP, 5 hydroxytryptophan; 5-HIAA, 5-hydroxyindol acetic acid; HCC, hepatocellular carcinoma; HSC, hepatic stellate cell; HGF, hepatocyte growth factor; IGF-1, ins
Exploring stemness gene expression and vasculogenic mimicry capacity in well- and poorly-differentiated hepatocellular carcinoma cell lines
Keywords: HGF، عامل رشد هپاتوسیت; VM, vasculogenic mimicry; HCC, hepatocellular carcinoma; EMT, epithelial–mesenchymal transition; CSCs, cancer stem cells; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor; MMPs, matrix metalloproteinases; qRT-PCR, quantitative rever
The roles of receptor tyrosine kinases and their ligands in the wound repair process
Keywords: HGF، عامل رشد هپاتوسیت; Ang, angiopoietin; DETC, dendritic epidermal T cell; EGF, epidermal growth factor; FGF, fibroblast growth factor; FGF-BP1, fibroblast growth factor binding protein 1; HB-EGF, heparin-binding epidermal growth factor; HGF, hepatocyte growth factor; IGF, ins
Age dependent forebrain structural changes in mice deficient in the autism associated gene Met tyrosine kinase
Keywords: HGF، عامل رشد هپاتوسیت; ANOVA, analysis of variance; bp, base pairs; CC, corpus callosum; ctx, cerebral cortex; HGF, hepatocyte growth factor; H,hipp, hippocampus; K–S, Kolmogorov–Smirnov; mm, millimeter; MRI, magnetic resonance imaging; P, postnatal day; PCR, polymerase chain r
Intramyocardial Injection of Platelet Gel Promotes Endogenous Repair and Augments Cardiac Function in Rats With Myocardial Infarction
Keywords: HGF، عامل رشد هپاتوسیت; biomaterials; endogenous recruitment; myocardial infarctionDMEM, Dulbecco's Modified Eagle's Medium; HGF, hepatocyte growth factor; IGF, insulin-like growth factor; LV, left ventricular; LVEF, left ventricular ejection fraction; MI, myocardial infarction;
Antiarrhythmic Potential of Mesenchymal Stem Cell Is Modulated by Hypoxic Environment
Keywords: HGF، عامل رشد هپاتوسیت; arrhythmia; mesenchymal stem cells; myocardial infarction; paracrine factorsAPD80, duration of the action potential at 80% repolarization; bFGF, basic fibroblast growth factor; CV, conduction velocity; Cx43, connexin 43; HGF, hepatocyte growth factor; IGF
PI3K signaling in the regulation of branching morphogenesis
Keywords: HGF، عامل رشد هپاتوسیت; BAD, Bcl-2-associated death promoter; ECM, extracellular matrix; EGF, epidermal growth factor; FGF, fibroblast growth factor; GDNF, glial cell line-derived neurotrophic factor; GPCR, G protein-coupled receptor; HGF, hepatocyte growth factor; MAPK, mitogen
Direct and Indirect Contribution of Human Embryonic Stem Cell–Derived Hepatocyte-Like Cells to Liver Repair in Mice
Keywords: HGF، عامل رشد هپاتوسیت; hES Cells; Hepatitis; Mouse Model; Stem Cell TherapyAd-luc, adenovirus expressing luciferase; BrdU, bromodeoxyuridine; DEX, dexamethasone; EB, embryoid body; ES, embryonic stem; GAS-6, growth arrest-specific 6; HGF, hepatocyte growth factor; HL, hepatocyt
Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways
Keywords: HGF، عامل رشد هپاتوسیت; HGF, hepatocyte growth factor; NAFLD/NASH, non-alcoholic fatty liver disease/steatohepatitis; ECM, extracellular matrix; MMP, matrix metalloproteinase; CCl4, carbon tetrachloride; TGF-β, transforming growth factor β; PDGF-β, platelet derived growth factor