دانلود مقالات ISI درباره خب، ججس + ترجمه فارسی

NF-κB-dependent transcriptional upregulation of cyclin D1 exerts cytoprotection against hypoxic injury upon EGFR activation

Keywords: خب، ججس; NF-κB, nuclear factor-κB; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; PI3K, phosphatidylinositol-3-kinase; MAPK, mitogen-activated protein kinases; Hh, hedgehog; STAT3, signal transducer and activator of transcription 3Nuclear fa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and synergizes with antimicrotubule drugs

Keywords: خب، ججس; Apoptosis; Cell death; Arsenic trioxide; Noxa; Hedgehog; RhabdomyosarcomaATO, arsenic trioxide; CI, combination index; FCS, fetal calf serum; FDA, Food and Drug Administration; Hh, Hedgehog; HPI, Hh pathway inhibitors; MDR, multi-drug resistance; MTT, (3-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Sonic hedgehog improves ischemia-induced neovascularization by enhancing endothelial progenitor cell function in type 1 diabetes

Keywords: خب، ججس; Type 1 diabetes; Sonic hedgehog pathway; Endothelial progenitor cells; Neovascularization; AKT/GSK-3βShh, sonic hedgehog; EPCs, endothelial progenitor cells; STZ, streptozocin; Hh, hedgehog; BM, bone marrow

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular Control of Atypical Protein Kinase C: Tipping the Balance between Self-Renewal and Differentiation

Keywords: خب، ججس; PKC, protein kinase C; aPKC, atypical protein kinase C; PrE, primitive endoderm; NB, neuroblast; Par, partitioning defective; Pros, Prospero; Brat, brain tumor; GMC, ganglion mother cell; Cdk2, cyclin-dependent kinase 2; HH, hedgehog; Ptch, patched; Smo,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of Evc2 in craniofacial tissues and craniofacial bone defects in Evc2 knockout mouse

Keywords: خب، ججس; EvC, Ellis-van Creveld; EVC2, Ellis-van Creveld 2; WT, wild type; KO, knockout; Het, heterozygous; IRES, internal ribosomal entry site; β-gal, β-galactosidase; IHC, immunohistochemistry; Hh, hedgehog; Smo, Smoothened; Ptch1, Patched1; SuFu, suppressor of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitors

Keywords: خب، ججس; AKT, protein kinase B; BCC, basal cell carcinoma; CNS, central nervous system; GPCR, G protein-coupled receptor; HBA, hydrogen bond acceptor; Hh, Hedgehog; MB, medulloblastoma; mTOR, mammalian target of rapamycin; N-G-L, NIH3T3-GRE-Luc reporter gene assay

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Spatial and temporal distribution of Patched-related protein in the Drosophila embryo

Keywords: خب، ججس; Drosophila; Patched-related; Hemocyte; EmbryogenesisSSD, sterol-sensing domain; HMGCR, HMG CoA reductase; SCAP, SREBP cleavage activating protein; NPC1, Niemann–Pick disease type C1; Ptc, Patched; Disp, Dispatched; Hh, Hedgehog; Ptr, Patched-related; SREB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

bantam miRNA is important for Drosophila blood cell homeostasis and a regulator of proliferation in the hematopoietic progenitor niche

Keywords: خب، ججس; PSC, posterior signaling center; Antp, Antennapedia; Col, Collier; Hh, hedgehog; HSC, hematopoietic stem cell; InR, insulin-like receptor; col-Gal4, P85col-Gal4; Foxo, forkhead-related transcription factor; Bam, bag of marbles; Rbf, retinoblastoma-family

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Miniaturized pre-clinical cancer models as research and diagnostic tools

Keywords: خب، ججس; μCCA, microscale cell culture analog; CAM-DR, cell-adhesion mediated drug resistance; CTCs, circulating tumor cells; ECM, extracellular matrix; HGF, hepatocyte growth factor; Hh, Hedgehog; MSCs, mesenchymal stem cells; VEGF, vascular endothelial cells gro

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Novel and recurrent EVC and EVC2 mutations in Ellis-van Creveld syndrome and Weyers acrofacial dyostosis

Keywords: خب، ججس; Ellis van Creveld syndrome; Weyers acrofacial dyostosis; EVC; EVC2AVCD, atrioventricular canal defect; CA, common atrium; CHD, congenital heart defect; EvCS, Ellis van Creveld syndrome; Hh, Hedgehog; MLPA, Multiplex Ligation-dependent Probe Amplification;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment

Keywords: خب، ججس; Pancreatic Stellate Cells; Pancreatic Cancer; Inflammation; Immune SurveillanceACh, acetylcholine; CTGF, connective tissue growth factor; ECM, extracellular matrix; GEM, genetic-engineered mouse; Hh, Hedgehog; HSC, hepatic stellate cell; IL, interleukin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Control of Cell Identity in Pancreas Development and Regeneration

Keywords: خب، ججس; Pancreas; Development; Regeneration; Cell IdentityArx, Aristaless homeobox gene; Cpa1, carboxypeptidase A1; Fgf, fibroblast growth factor; Hh, hedgehog; Ngn3, neurogenin-3; PDA, pancreatic ductal adenocarcinoma; PDL, pancreatic duct ligation; Ptf, pancrea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways

Keywords: خب، ججس; JATD, Jeune asphyxiating thoracic dystrophy; SRP, Short-rib polydactyly; OA, Osteoarthritis; IFT, Intraflagellar transport; Ptch1, Patched 1; Smo, Smoothened; Hh, Hedgehog; Shh, Sonic Hh; shRNA, Small hairpin RNA; BMSC, Bone marrow-derived stromal cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells

Keywords: خب، ججس; Hh, hedgehog; mESCs, mouse embryonic stem cells; sqRT-PCR, semi-quantitative reverse transcriptase polymerase chain reactionEmbryonic stem cell; Gli; Microarray; Mouse; Oct3/4; Transcriptional heterogeneity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma

Keywords: خب، ججس; Hedgehog; Pancreatic cancer; Development; Stroma; mRNA-SeqCDA, cysteine deaminase; EDIL3, EGF-like repeats and discoidin I-like domains 3; GSEA, gene set enrichment analysis; HH, Hedgehog; ITGB4, integrin beta 4; PDAC, pancreatic ductal adenocarcinoma; PL

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin

Keywords: خب، ججس; Hh, hedgehog; smo, smoothened; rShh, recombinant sonic hedgehog; PI3K, phosphatidylinositol 3-kinase; mTOR, mammalian target of rapamycin; GSK3β, Glycogen synthase kinase 3β; AML, acute myeloid leukemiaHedgehog/Gli; mTOR; AML; GANT61; Rapamycin; Apoptosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

A novel role for FOXA2 and SHH in organizing midbrain signaling centers

Keywords: خب، ججس; bi, Bilaterally electroporated; CYC, Cyclopamine; DI, Diencephalon; E, Embryonic day; EP, Electroporated; FP, Floor plate; HH, Hedgehog; H&H, Hamburger & Hamilton; HB, Hindbrain; hn, Hensen's Node; LFP, Lateral floor plate; MB, Midbrain; me, Mesendoderm;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening

Keywords: خب، ججس; Hh, Hedgehog; HPE, holoprosencephaly; CLP, cleft lip and palate; Ptc1, Patched; Smo, Smoothened; Shh, Sonic Hedgehog; MEF, mouse embryonic fibroblastsHedgehog signaling; Cyclopamine; Small molecule screening; Birth defects

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Intestinal stem cells and epithelial–mesenchymal interactions in the crypt and stem cell niche

Keywords: خب، ججس; Ascl2, achaete scutelike 2; BMP, bone morphogenetic protein; CBC, crypt base columnar; GFP, green fluorescent protein; Hh, Hedgehog; ISC, intestinal stem cell; Lgr, leucine-rich repeat containing G-protein-coupled receptor; mRNA, messenger RNA; MSC, mesen

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

Keywords: خب، ججس; Shh, sonic hedgehog; Smo, smoothened; Ptch1, Patched-1; Hh, Hedgehog; HMEC, human mammary epithelial cells; FTase II, H-Cys-4-Abz-Met-OH; GST, glutathione S transferase; GFP, green fluorescent protein; MEK, mitogen-activated protein kinase kinase; Erk, ex

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Stability study of the human G-protein coupled receptor, Smoothened

Keywords: خب، ججس; GPCR, G-Protein Coupled Receptor; hSmo, Smoothened; MAP, Multitag Affinity Purification; DDM, dodecyl-β-D-maltoside; FS, fluorinated surfactant; SPR, surface plasmon resonance; RU, resonance unit; Hh, Hedgehog; HA, hemagglutinin; CPN, cyclopamineHeterolog

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway

Keywords: خب، ججس; Hh, hedgehog; Gli, glioma-associated oncogene homolog; Smo, smoothened; Ptch1, patched 1; SuFu, suppressor of fused; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; Gli-Luc, Gli-responsible firefly luciferase; HATU, 2-(1H-7-azabenzo[d][1,2,3]triazol-1-yl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Indian Hedgehog Regulates Intestinal Stem Cell Fate Through Epithelial−Mesenchymal Interactions During Development

Keywords: خب، ججس; Hedgehog Signaling; ECM; MMP; BMPBMP, bone morphogenetic protein; ECM, extracellular matrix; Hh, hedgehog; Hhip, Hedgehog interacting protein; Ihh, Indian Hedgehog; ISC, intestinal stem cell; ISEMF, intestinal subepithelial myofibroblast; MMP, matrix meta

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Pancreatic Duct Glands Are Distinct Ductal Compartments That React to Chronic Injury and Mediate Shh-Induced Metaplasia

Keywords: خب، ججس; Pancreatic Duct Glands; Sonic Hedgehog; PanIN; GI MetaplasiaBrdU, bromodeoxyuridine; CP, chronic pancreatitis; GI, gastrointestinal; Hh, hedgehog; HPDE cells, human pancreatic ductal epithelial cells; PanIN, pancreatic intraepithelial neoplasia; PAS, Peri

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Geometric control of tissue morphogenesis

Keywords: خب، ججس; AP, anterior–posterior; Bcd, Bicoid; Dpp, Decapentaplegic; DV, dorsal–ventral; ECM, extracellular matrix; FGF, fibroblast growth factor; GDNF, glial cell-derived neurotrophic factor; Hh, hedgehog; TGFβ, transforming growth factor-β; 2D, two-dimensional; 3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Functional studies of membrane-bound and purified human Hedgehog receptor Patched expressed in yeast

Keywords: خب، ججس; Hh, Hedgehog; Shh, Sonic Hedgehog; hSmo, human Smoothened; hPtc, human Patched; AOX1, alcohol oxidase 1; PMSF, phenylmethylsulfonyl fluoride; CBD, calmodulin binding domain; HA, hemagglutinin A; PCR, polymerase chain reaction; SDS-PAGE, sodium dodecyl sul

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Reduced Level of Smoothened Suppresses Intestinal Tumorigenesis by Down-Regulation of Wnt Signaling

Keywords: خب، ججس; Apc, adenomatous polyposis coli; Gli, glioma-associated oncogene homologue; Hh, Hedgehog; Smo, Smoothened

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas

Keywords: خب، ججس; HH, hedgehog; NSCLC, non-small cell lung cancer; FOXM1, Forkhead Box M1; SHH, sonic hedgehog; PTCH1, patched1; SMO, Smoothened; SCLC, small cell lung cancer; SuFu, suppressor of fusedGLI; FOXM1; Hedgehog; NSCLC; PTCH1; SHH; SMO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning

Keywords: خب، ججس; Dhh, Desert Hedgehog; E, embryonic day; Hh, Hedgehog; Ihh, Indian Hedgehog; ME, muscularis externa; MM, muscularis mucosa; Ptch, Patched; Shh, Sonic Hedgehog; SM, smooth muscle; SMA, smooth muscle actin; Smo, Smoothened; VACTERL, vertebral, anal, cardiac,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Nucleocytoplasmic transport as a driver of mammalian gametogenesis

Keywords: خب، ججس; ACT, activator of CREM in the testis; AR, androgen receptor; CREB, cyclic AMP response element binding protein; CREM, cyclic AMP response element modulator; dpc, days post coitum; dpp, days post partum; Hh, hedgehog; IMP, importin; NES, nuclear export sig

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

The Role of the Visceral Mesoderm in the Development of the Gastrointestinal Tract

Keywords: خب، ججس; BMP, bone morphogenetic protein; E, embryonic day; ECM, extracellular matrix; ENS, enteric nervous system; FGF, fibroblast growth factor; GC, glucocorticoid; GI, gastrointestinal; Hh, Hedgehog; IGF, insulin-like growth factor; ISEMF, intestinal subepithel

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Hedgehog Signal Activation in Gastric Pit Cell and in Diffuse-Type Gastric Cancer

Keywords: خب، ججس; DHH, Desert hedgehog; GLI, glioma-associated oncogene homolog; Hh, Hedgehog; IHH, Indian hedgehog; KRT8, cytokeratin 8; PCNA, proliferating cell nuclear antigen; PTCH, patched; RT-PCR, reverse-transcription polymerase chain reaction; SHH, Sonic hedgehog;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه