The anti-diabetic drug metformin inhibits vascular endothelial growth factor expression via the mammalian target of rapamycin complex 1/hypoxia-inducible factor-1α signaling pathway in ELT-3 cells
Keywords: HIF-1، عامل القایی هیپوکسی 1; VEGF, vascular endothelial growth factor; HIF-1, hypoxia inducible factor-1; PHD, prolylhydroxylase; HRE, hypoxia response element; PI3K, phosphatidyl inositol 3-kinase; mTORC1, mammalian target of rapamycin complex 1; mTOR, mammalian target of rapamycin;