
																
																	High-level extracellular production of Rhizopus oryzae lipase in Pichia pastoris via a strategy combining optimization of gene-copy number with co-expression of ERAD-related proteins
																
																
																
															Keywords: تخمیر با چگالی بالا; Rhizopus oryzae lipase; Heterologous overexpression; Pichia pastoris; Combined strategy; High-density fermentation;