Keywords: گیرنده H4 هیستامینین; Mast cells; Histamine; Histamine H4 receptor; Chemotaxis;
مقالات ISI گیرنده H4 هیستامینین (ترجمه نشده)
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Activation of ERK/CREB pathway in noradrenergic neurons contributes to hypernociceptive phenotype in H4 receptor knockout mice after nerve injury
Keywords: گیرنده H4 هیستامینین; Neuropathic pain; Histamine H4 receptor; ERK; CREB; Spinal noradrenergic neurons; (ATF3); activating transcription factor 3; (CREB); cAMP response element-binding protein; (DβH); dopamine beta-hydroxylase; (ERK); Extracellular signal-regulated kinases;
Functional histamine H3 and adenosine A2A receptor heteromers in recombinant cells and rat striatum
Keywords: گیرنده H4 هیستامینین; A2AR; Adenosine A2A receptor; cAMP; Cyclic adenosine monophosphate; D1R; Dopamine D1 receptor; D2R; Dopamine D2 receptor; dMSNs; Direct pathway striatal medium-sized spiny neurons; GABA; γ-Aminobutyric acid; GPCRs; G-protein coupled receptors; H2R; Hista
Preliminary study of histamine H4 receptor expressed on human CD4+ T cells and its immunomodulatory potency in the IL-17 pathway of psoriasis
Keywords: گیرنده H4 هیستامینین; AP; active psoriasis; DAPI; 4â²,6-diamidino-2-phenylindole; ELISA; enzyme-linked immunosorbent assay; H4R; histamine H4 receptor; IL; interleukin; IP; inactive psoriasis; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBMC; peripheral
The HRH4 rs11662595 mutation is associated with histamine H4 receptor dysfunction and with increased epithelial-to-mesenchymal transition progress in non-small cell lung cancer
Keywords: گیرنده H4 هیستامینین; CI; confidential interval; EMT; epithelial-to-mesenchymal transition; HR; hazard ratio; HRH4; histamine H4 receptor; MAF; minor allele frequency; NSCLC; Non-small cell lung cancer; OS; overall survival; PFS; progression-free survival; SNP; single-nucleoti
Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists
Keywords: گیرنده H4 هیستامینین; Histamine; Histamine H4 receptor; Asthma; Atopic dermatitis;
A search for presynaptic inhibitory histamine receptors in guinea-pig tissues: Further H3 receptors but no evidence for H4 receptors
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Histamine H3 receptor; Guinea-pig atrium; Presynaptic receptor; Noradrenaline release; Acetylcholine release;
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor-H1/H4-receptor selectivity
Keywords: گیرنده H4 هیستامینین; Histamine H1 receptor; Histamine H4 receptor; Diaminopyrimidines; Dual H1R/H4R ligands; Molecular dynamics;
Role of histamine H4 receptor ligands in bleomycin-induced pulmonary fibrosis
Keywords: گیرنده H4 هیستامینین; COX-2; cyclooxygenase-2; H4R; histamine H4 receptor; 8OHdG; 8-hydroxy-2⿲-deoxyguanosine; JNJ7777120; 1-[(5-chloro-1H-indol-2yl)carbonyl]-4methylpiperazine; MPO; myeloperoxidase; PGE2; prostaglandin E2; ROS; reactive oxygen species; TBARS; thiobarbituric
The histamine H4-receptor and the central and peripheral nervous system: A critical analysis of the literature
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Nervous system; Neuron; Microglia; Antibody specificity; Publication bias; A 943931; H4R antagonist (4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine); ACh; acetylcholine; AKT; protein k
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs
Keywords: گیرنده H4 هیستامینین; Histamine H1 receptor; Histamine H4 receptor; Dual/selective H1R/H4R ligands; Dual hH1R/h5-HT2AR ligands; Oxazepine derivatives; Oxepine derivatives;
Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells
Keywords: گیرنده H4 هیستامینین; Clozapine; Agranulocytosis; HL-60 cells; Histamine H4 receptor; Apoptosis;
Proinflammatory role of the histamine H4 receptor in dextrane sodium sulfate-induced acute colitis
Keywords: گیرنده H4 هیستامینین; Experimental colitis; Histamine H4 receptor; Histamine; Cytokines; Inflammatory bowel diseases
Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics
Keywords: گیرنده H4 هیستامینین; Ligand binding pathway; Histamine H4 receptor; Histamine; Molecular dynamics;
(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; 1,3,5-Triazin-2-amines; 4-Methylpiperazines; Anti-inflammatory properties; PATVLDHTCBKUPZ-AATRIKPKSA-N;
Functional characterization of histamine H4 receptor on human mast cells
Keywords: گیرنده H4 هیستامینین; LAD-2; Laboratory of allergic diseases 2; HMC-1; Human mast cell line-1; MCP-1/CCl2; Monocyte chemo attractant protein-1; H4R; Histamine H4 receptor; MC; Mast cells; LTB4; Leukotriene B4; CyLTs; Cysteinyl leukotrienes; cAMP; Cyclic AMP; RANTES; Regulated
Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; 4-Methylpiperazines; 2,4,6-Trisubstituted 1,3,5-triazines; Anti-inflammatory propertiesWWJYDYWCKUZUPY-UHFFFAOYSA-N; JLCGALNAVFMRDY-UHFFFAOYSA-N
MinireviewExpression of the histamine H4 receptor in dermal and articular tissues
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Keratinocytes; Dermal fibroblasts; Chondrocytes; Synoviocytes; Pruritus; Dermatitis; Rheumatoid arthritis; Osteoarthritis;
A novel series of histamine H4 receptor antagonists based on the pyrido[3,2-d]pyrimidine scaffold: Comparison of hERG binding and target residence time with PF-3893787
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; GPCR; Pyrido[3,2-d]pyrimidine; hERG; Residence time; PF-3893787;
Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics
Keywords: گیرنده H4 هیستامینین; Histamine; H4R antagonist; GPCR; Binding kinetics; Fragment optimization; GPCRs; G protein-coupled receptors; H1R; histamine H1 receptor; H2R; histamine H2 receptor; H3R; histamine H3 receptor; H4R; histamine H4 receptor; SAR; structure-activity relatio
Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A
Keywords: گیرنده H4 هیستامینین; Fragment-based lead discovery (FBLD); Chemogenomics; Serotonin 5-HT3A receptor; Histamine H4 receptor; Dual activity ligand; G-protein coupled receptor (GPCR); Ligand gated ion channel (LGIC);
PerspectiveThe histamine H4 receptor: Targeting inflammatory disorders
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Antagonist; Allergy; Autoimmune disease; Inflammation; Immunology;
Histamine H4 receptor antagonist reduces dermal inflammation and pruritus in a hapten-induced experimental model
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Atopic dermatitis; Pruritus; Skin inflammation; JNJ7777120; Mast cell
Pulmonary, Gastrointestinal and Urogenital PharmacologySelective histamine H3 and H4 receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach
Keywords: گیرنده H4 هیستامینین; Histamine H3 receptor; Histamine H4 receptor; Binding; Gastric lesions; HCl;
Mepyramine–JNJ7777120-hybrid compounds show high affinity to hH1R, but low affinity to hH4R
Keywords: گیرنده H4 هیستامینین; Histamine H1 receptor; Histamine H4 receptor; Mepyramine; JNJ7777120; Hybrid compounds; Molecular dynamics
N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands
Keywords: گیرنده H4 هیستامینین; Histamine H3 receptor; Histamine H4 receptor; Imidazole carbamates
Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: Effects of substitution about the rigidifying ring
Keywords: گیرنده H4 هیستامینین; Histamine; Histamine H4 receptor
Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates
Keywords: گیرنده H4 هیستامینین; Histamine H3 receptor; Histamine H4 receptor; Imidazole derivatives
Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: Synthesis, pharmacological evaluation, and cross-target QSAR studies
Keywords: گیرنده H4 هیستامینین; Histamine H3 receptor; Histamine H4 receptor; GPCR; Cross-target QSAR; Selectivity; Clobenpropit analogs
Histamine H4 receptor–RGS fusion proteins expressed in Sf9 insect cells: A sensitive and reliable approach for the functional characterization of histamine H4 receptor ligands
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Fusion protein; RGS protein; Steady-state GTPase assay; Constitutive activity; Gi-proteins
Electrophysiology-based analysis of human histamine H4 receptor pharmacology using GIRK channel coupling in Xenopus oocytes
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; GIRK channel; Thioperamide; Clobenpropit; Xenopus oocyte; Voltage-clamp
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus
Keywords: گیرنده H4 هیستامینین; Histamine; histamine H1 receptor; histamine H4 receptor; pruritus; mast cellsH1R, Histamine H1 receptor; H2R, Histamine H2 receptor; H3R, Histamine H3 receptor; H4R, Histamine H4 receptor; H4R−/−, Histamine H4 receptor knockout; H4R+/+, Histamine H4 recep
The histamine H4 receptor: A novel modulator of inflammatory and immune disorders
Keywords: گیرنده H4 هیستامینین; Histamine H4 receptor; Immune cell function; Inflammation; Asthma; PruritusAHR, airway hyperresponsiveness; H4R, histamine H4 receptor; H3R, histamine H3 receptor; H2R, histamine H2 receptor; H1R, histamine H1 receptor; IBD, inflammatory bowel disease; IL
Suppression of ischemia/reperfusion liver injury by histamine H4 receptor stimulation in rats
Keywords: گیرنده H4 هیستامینین; Histamine; Histamine H4 receptor; Liver ischemia; Portal vein; (Rat)