Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity
Keywords: HLH، Helix-loop-helix; IKKβ, inhibitor of κB kinase b; NF-κB, nuclear factor-κB; NEMO, NF-κB essential regulator; TNF-α, tumor necrosis factor-α; HLH, helix-loop-helix; shRNA, small hairpin RNA; NBD, NEMO binding domain; HSP90, heat shock protein 90; KEAP-1, Kelch-like ECH-asso