دانلود مقالات ISI درباره HLM ها + ترجمه فارسی

آزمایش اکسایشی واکنش پذیر آنزیمی برای ارزیابی اثر متابولیت های فوتوتوسیک

Enzymatic reactive oxygen species assay to evaluate phototoxic risk of metabolites

Keywords: HLM ها; CV; coefficients of variation; eROS; enzymatic reactive oxygen species; FA; fenofibric acid; FF; fenofibrate; HLMs; human liver microsomes; mROS; micellar reactive oxygen species; NaPB; sodium phosphate buffer; NBT; nitroblue tetrazolium; ROS; reactive ox

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic profiling of five flavonoids from Dragon's Blood in human liver microsomes using high-performance liquid chromatography coupled with high resolution mass spectrometry

Keywords: HLM ها; CYPs; cytochrome P450s; DB; Dragon's Blood; HLMs; human liver microsomes; HPLC-HR-MS; high performance liquid chromatography coupled with high resolution mass spectrometry; tR; retention time; Dragon's Blood; Human liver microsomes; HPLC-HR-MS; Metabolite

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

تعیین مشخصه-انتخاب به سمت طبقه بندی بر اساس شاخص تعامل

Set characterization-selection towards classification based on interaction index

Keywords: HLM ها; Choquet; Subset characterization; HLMS; Generalized Shapley index

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects

Keywords: HLM ها; CYPs; cytochrome P450s; HDIs; herb-drug interactions; HLMs; human liver microsomes; NADP＋; β-nicotinamide adenine dinucleotide phosphate; QSAR; quantitative structure activity relationship; CoMFA; comparative molecular field analysis; LC-MS; liquid c

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibitory Effects of Danshen components on CYP2C8 and CYP2J2

Keywords: HLM ها; Cytochrome P450; Inhibitory effects; Danshen; CYP2C8; CYP2J2; Herb-drug interactions; AA; arachidonic acid; CA; caffeic acid; Cry; cryptotanshinone; CYPs; Cytochrome P450 enzymes; DSS; danshensu; DI; dihydrotanshinone I; EETs; epoxyeicosatrienoic acids; F

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine

Keywords: HLM ها; Aconitum carmichaeli Debx.; Aconitum alkaloids; Pharmacokinetics; Herb-drug interactions; Toxicology; Personalized medicine; DMEs; drug-metabolizing enzymes; ETs; efflux transporters; BB; bioavailability barrier; DDAs; diester-diterpene alkaloids; MDAs; m

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells

Keywords: HLM ها; Acetylshikonin; CYP2J2; Inhibition; Anti-cancer; HLMs; human liver microsomes; HCC; Hepatocellular carcinoma; DMSO; dimethyl sulfoxide; G6P; glucose-6-phosphate; G6PDH; G6P dehydrogenase; NADP+; β-nicotinamide dinucleotide phosphate; EETs; Epoxyeicosatri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of diosmetin on nine cytochrome P450 isoforms, UGTs and three drug transporters in vitro

Keywords: HLM ها; Diosmetin; Cytochrome P450; UDP-glucuronyltransferases; Hepatic uptake transporters; Drug-drug interactions; CYPs; Cytochrome P450 enzymes; DDI; drug-drug interactions; HDI; herb-drug interactions; HLMs; human liver microsomes; NTCP; Na+-taurocholate cotr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast

Keywords: HLM ها; ADMET; absorption, distribution, metabolism, excretion, and toxicity; API; active pharmaceutical ingredient; CPR; NADPH-cytochrome P450 oxidoreductase; CYP; cytochrome P450; EMM; Edinburgh Minimal Medium; HLMs; human liver microsomes; RLU; relative lumine

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

k-maxitive fuzzy measures: A scalable approach to model interactions

Keywords: HLM ها; Choquet; Fuzzy measure; HLMS; Shapley; Möbius; k-order measures;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of ursolic acid

Keywords: HLM ها; Ursolic acid; UDP-glucuronosyltransferases; Metabolism pathway; Metabolism characterization; UA; ursolic acid; HLMs; human liver microsomes; HIMs; human intestinal microsomes; UGTs; UDP-glucuronosyltransferases; DDI; drug-drug interactions; RILD; Resear

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450

Keywords: HLM ها; AhR; Aryl Hydrocarbon Receptor; CCBs; calcium channel blockers; CYP; cytochrome P450; DEX; dexamethasone; DMSO; dimethysulfoxide; GR; Glucocorticoid Receptor; HLMs; human liver microsomes; PXR; pregnane X receptor; RIF; rifampicin; TCDD; 2,3,7,8 tetrachlo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Identification and characterization of reactive metabolites in myristicin-mediated mechanism-based inhibition of CYP1A2

Keywords: HLM ها; MBI; mechanism-based inhibition; RMs; reactive metabolites; CYPs; cytochrome P450 enzymes; GSH; reduced glutathione; HLMs; human liver microsomes; NADPH; β-nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt; MI complex; metabolite

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases

Keywords: HLM ها; HLMs; human liver microsomes; UGTs; UDP-glucuronosyltransferases; SGR; Structure-glucuronidation relationship; HPLC; high performance liquid chromatography; NADPH; nicotinamide adenine dinucleotide phosphate reduced; CYP450s; cytochrome P450s; PAPS; 3â€

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties

Keywords: HLM ها; CuAAC; copper-catalysed azide-alkyne cycloaddition; CE; carboxylesterase; c log P; calculated Log P; HLMs; human liver microsomes; HSA; human serum albumin; CYP450; cytochrome P450; Carbohydrate; Prodrug; Esterase; Metabolic stability; Click chemistr

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5

Keywords: HLM ها; CYP; cytochrome P450; CPR; cytochrome P450 reductase; CER; cerivastatin; AQ; amodiaquine; PAC; paclitaxel; RG; rosiglitazone; DEAQ; N-de ethyl amodiaquine; DLPC; L-α-dilauryl-sn-glycero-3-phosphocholine; HLMs; human liver microsomes; SIR EI+; selective i

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه