دانلود مقالات ISI درباره Hpxr + ترجمه فارسی

ارزیابی عصاره گینگو بیلوبا به عنوان فعال کننده گیرنده گلوکوکورتیکوئید انسانی

Evaluation of Ginkgo biloba extract as an activator of human glucocorticoid receptor

Keywords: CAR; constitutive androstane receptor; CYP2B6; cytochrome P450 2B6; CYP3A4; cytochrome P450 3A4; DMSO; dimethyl sulfoxide; GR; glucocorticoid receptor; HBSS; Hanks' balanced salt solution; hCAR; human constitutive androstane receptor; hGR; human glucoco

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Poly- and perfluorinated compounds activate human pregnane X receptor

Keywords: Poly- and perfluorinated compounds; PFCs; Human pregnane X receptor; hPXR; Reporter gene assays;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

QSAR development and profiling of 72,524 REACH substances for PXR activation and CYP3A4 induction

Keywords: AD; applicability domain; AOP; adverse outcome pathway; CYP; cytochrome P450; CYP3A4; human cytochrome P450 isoform 3A4; DTU; Technical University of Denmark; Food; National Food Institute; hPXR; full-length human Pregnane X Receptor; hPXR-LBD; human Preg

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease

Keywords: 3-Hydroxyflavone (PubChem CID: 11349); Galangin (PubChem CID: 5281616); Datiscetin (PubChem CID: 5281610); Kaempferol (PubChem CID: 5280863); Morin (PubChem CID: 5281670); Quercetin dihydrate (PubChem CID: 5284452); Isorhamnetin (PubChem CID: 5281654); Ta

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently

Keywords: CMV; cytomegalovirus; DBD; DNA-binding domain; GAL4; yeast regulatory protein GAL4; hPXR; human PXR; LBD; ligand-binding domain; NR1I2; nuclear receptor subfamily 1 group I member 2, a. k. a pregnane X receptor; pbPXR; polar bear PXR; PXR; pregnane X rece

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A ligand-entry surface of the nuclear receptor superfamily consists of the helix H3 of the ligand-binding domain

Keywords: hAR; human androgen receptor; hCAR; human constitutive androstane receptor; hCOUP-TFI; human chicken ovalbumin upstream promoter-transcription factor-I; hCOUP-TFII; human chicken ovalbumin upstream promoter-transcription factor-II; ssDAF-12; Strongyloides

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Effect on metabolic enzymes and thyroid receptors induced by BDE-47 by activation the pregnane X receptor in HepG2, a human hepatoma cell line

Keywords: PXR; pregnane X receptor; hPXR; human pregnane X receptor; PBDE; polybrominated diphenyl ethers; BDE-47; 2,2′,4,4′-tetra-bromodiphenyl ether; CYP3A4; cytochrome P450 3A4; TRs; thyroid receptors; TREs; thyroid hormone response elements; UGTs; uridine d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Effect of Chinese herbs on CYP3A4 activity and expression in vitro

Keywords: TCM; Traditional Chinese Medicine; PK; pharmacokinetic; CYP3A4; cytochrome P450 3A4; PD; pharmacodynamic; hPXR; human pregnane X receptor; Herb-drug interactions; Pharmacokinetics; Traditional Chinese Medicine; Oldenlandia diffusa; Rehmannia glutinosa;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors

Keywords: AOP; adverse outcome pathway; hCAR; human constitutive androstane receptor; mCAR; mouse constitutive androstane receptor; rCAR; rat constitutive androstane receptor; cDNA; complementary DNA; CITCO; 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldeh

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Research ReportPregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier

Keywords: ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; BCRP; breast cancer related protein; BMDP; brain multidrug resistance protein; CNS; central nervous system; Fumitremorgin; C; hPXR; human PXR; Mrp2; multidrug resistance-associ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

In silico identification of human pregnane X receptor activators from molecular descriptors by machine learning approaches

Keywords: hPXR; Machine learning approaches; Applicability domain;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway

Keywords: LPS; lipopolysaccharide; NS; normal saline; HCE1; human carboxylesterases 1; HCE2; human carboxylesterases 2; mCE1; mouse carboxylesterases 1; mCE2; mouse carboxylesterases 2; CYP450; cytochrome P450; DMEs; drug metabolism enzymes; PXR; pregnane X recepto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

N-1H-Benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists

Keywords: Nuclear receptor; hPXR; Docking; Drug design

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه