دانلود مقالات ISI درباره Hsp90 + ترجمه فارسی

The role of protein synthesis in cell cycling and cancer

Keywords: Cell cycle; Elongation factor 2; Elongation factor 2 kinase; Apoptosis; Cancer; AMPK; AMP-activated Kinase; cAMP; cyclic AMP; PKA; Protein Kinase A; FLIP; FLICE-Like Inhibitor Protein; XIAP; X-linked Inhibitor of Apoptosis; EF2; Elongation Factor 2; cdc2/

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Heat shock protein 90 regulates the stability of MEKK3 in HEK293 cells

Keywords: Hsp90; MEKK3; Geldanamycin; MG-132; HEK293 cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line

Keywords: Hsp90; Neuroprotection; Novobiocin; Geldanamycin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of stress-related genes in tomato plants exposed to arsenic and chromium in nutrient solution

Keywords: As(V), arsenate; Cr, chromium; GR, glutathion reductase; MT, metallothioneinGlutathion reductase; Heavy metals; Hsp90; Lycopersicon esculentum; Metallothionein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold

Keywords: Hsp90; Cancer; Naphthoquinone; MCF-7; Anti-proliferation; High-throughput screening

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3β

Keywords: NDRG1; HSP90; SKG1; GSK3β; Geldanamycin; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake

Keywords: Multicellular spheroids; Positron Emission Tomography; HSP90; Breast cancer; Growth inhibition

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

The selenium to selenoprotein pathway in eukaryotes: More molecular partners than anticipated

Keywords: RNA–protein interaction; SBP2; SECIS; Selenocysteine; Selenocysteine synthase; Hsp90; Selenoprotein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The molecular chaperone heat shock protein-90 positively regulates rotavirus infection

Keywords: Rotavirus; NFκB; Akt; HSP90; 17-AAG; Geldanamycin analogs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Hsp90 and a tyrosine embedded in the Hsp90 recognition loop are required for the Fer tyrosine kinase activity

Keywords: Hsp90; Fer; Kinase activity; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of neurotoxic insecticides on heat-shock proteins and cytokine transcription in Chinook salmon (Oncorhynchus tshawytscha)

Keywords: Chlorpyrifos; Esfenvalerate; Sublethal effects; Hsp70; Hsp60; Hsp90; TGF-β; IL-1β; IGF-1; Mx-protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

Keywords: ALC; alveolar liquid clearance; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; BALF; broncholaveolar lavage fluid; DISC; death inducing signaling complex; Hsp90; heat shock protein 90; iNOS; inducible nitric oxide synthase; MLC; myosin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia

Keywords: Zebrafish; Cyclopia; Midline bifurcation; Squint; Nodal; Wnt5b; Wnt11; Hsp90;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

From protein–protein interaction to therapy response: Molecular imaging of heat shock proteins

Keywords: Molecular imaging; Heat shock protein; HSP70; HSP90; Reporter gene; Positron emission tomography

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

New developments in Hsp90 inhibitors as anti-cancer therapeutics: Mechanisms, clinical perspective and more potential

Keywords: Hsp90; Inhibitor; Cancer therapy; Client protein; Co-chaperone; Hsp70; Cdc37; 17-AAG; Tanespimycin; Derrubone; Shepherdin; Tubocapsenolide A; Celastrol

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53

Keywords: Hsp90; Microtubule; Acetylation; Akt; p53;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma

Keywords: Hsp90; ER stress; Bax; Ca2+; Mitochondrial membrane potential

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Knockdown of the co-chaperone Hop promotes extranuclear accumulation of Stat3 in mouse embryonic stem cells

Keywords: mESC; RNAi; Heat shock protein; Molecular chaperone; Hsp90; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)

Keywords: hsp90; Novobiocin; Coumarin inhibitors; Anti-tumour; Steroid receptors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Conformational significance of EH21A1–A4, phenolic derivatives of geldanamycin, for Hsp90 inhibitory activity

Keywords: Hsp90; Inhibitor; Ansamycin; Geldanamycin; Conformation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Protein phosphatase 5

Keywords: Phosphatase; Tetratricopeptide repeat protein; Protein phosphatase 5 (PP5, Ppp5); Phosphoprotein; Steroid receptor; Glucocorticoid receptor; Chaperone; HSP90; MAPK

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Cisplatin differently affects amino terminal and carboxyl terminal domains of HSP90

Keywords: HSP90; Molecular chaperone; Cisplatin; Aggregation prevention; Conformational change

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Keywords: Hsp90; Heat shock protein 90; Cancer therapeutic; Cancer inhibitor; X-ray structure; Her2; ATP; Carbazol-4-one; Benzamide; Hsp70

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone

Keywords: Dihydroxylphenyl amides; Hsp90; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Repression of Ah receptor and induction of transforming growth factor-β genes in DEN-induced mouse liver tumors

Keywords: ALDH3A1; aldehyde dehydrogenase-3A1; AHR; aryl hydrocarbon receptor; AHRE; aryl hydrocarbon receptor response element; AIP; AHR-interacting protein; ALL; acute lymphoblastic leukemia; ARA9; Ah receptor-associated protein 9; ARNT; aryl hydrocarbon receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Geldanamycin enhances hepatocyte growth factor stimulation of eNOS phosphorylation in endothelial cells

Keywords: HSP90; Geldanamycin; Akt; HGF; Nitric oxide; Endothelial nitric oxide synthase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner

Keywords: Parkinson's disease; PINK1; Hsp90; Cdc37; Proteasome; Stability

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Endothelial nitric oxide (NO) and its pathophysiologic regulation

Keywords: Nitric oxide; Hsp90; Cardiovascular disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant acute promyelocytic leukemia cells

Keywords: Acute promyelocytic leukemia; APL; 17AAG; Heat shock protein; HSP90; Apoptosis; Therapy; Geldanamycin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of Hsp90 Leads to Cell Cycle Arrest and Apoptosis in Human Malignant Pleural Mesothelioma

Keywords: Hsp90; 17-AAG; Cell cycle arrest; Apoptosis; Mesothelioma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1

Keywords: Melusin; CHORD containing proteins; Hsp90; Sgt1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Cadmium affects the expression of heat shock protein 90 and metallothionein mRNA in the Pacific oyster, Crassostrea gigas

Keywords: Cadmium; Gene expression; Hemolymph; HSP90; MT; Pacific oyster

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Development and validation of a rapid and sensitive high-performance liquid chromatography–mass spectroscopy assay for determination of 17-(allylamino)-17-demethoxygeldanamycin and 17-(amino)-17-demethoxygeldanamycin in human plasma

Keywords: 17-(Allylamino)-17-demethoxygeldanamycin; 17AAG; 17-(Amino)-17-demethoxygeldanamycin; 17AG; HSP90; LC–MS–MS

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Cloning, purification and characterization of the Caenorhabditis elegans small glutamine-rich tetratricopeptide repeat-containing protein

Keywords: Small glutamine-rich tetratricopeptide repeat-containing protein; SGT; TPR; Hsp70; Hsp90; Co-chaperone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Hsp90 inhibitors reduce influenza virus replication in cell culture

Keywords: Influenza viruses replication; RNA polymerase; Hsp90; Geldanamycin; 17 AAG; Antiviral agents

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities

Keywords: Hsp90; Online screening; Affinity chromatography; Inhibitors

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Histone deacetylase inhibitor SAHA induces ERα degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling

Keywords: HDACi; SAHA; ERα; Breast cancer; CHIP; Hsp90

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis of Hsp90 inhibitor dimers as potential antitumor agents

Keywords: Heat shock protein; Hsp90; PU3; Anticancer; Structure-based drug design

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Stability of the Hsp90 Inhibitor 17AAG Hydroquinone and Prevention of Metal‐Catalyzed Oxidation

Keywords: 17AAG; hydroquinone; Hsp90; copper; oxidation; human serum albumin; NQO1; reduction; stability; solubility;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells

Keywords: HDACI, histone deacetylase inhibitor; AML, acute myelogenous leukemia; ALL, acute lymphoblastic leukemia; PDGFR, platelet derived growth factor receptor; FLT3, fms-like tyrosine kinase 3AML; FLT3; HSP90; HDAC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Nuclear translocation of the phosphoprotein Hop (Hsp70/Hsp90 organizing protein) occurs under heat shock, and its proposed nuclear localization signal is involved in Hsp90 binding

Keywords: Hop; Heat shock protein; Phosphorylation; Hsp90; Co-chaperone; Nuclear localization signal;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential

Keywords: Resorcylic acid lactones (RALs); Kinase inhibitors; HSP90; Total synthesis; Combinatorial synthesis; Solid-phase synthesis; Polymer supported reagentsLactone de l'acide resorcyclique; Inhibiteurs de kinasas; HSP90; Synthèse total; Synthèse combinatoire; P

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Altered gene expression in busulfan-resistant human myeloid leukemia

Keywords: Busulfan; Myeloid leukemia; Drug resistance; Apoptosis; HSP90

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of

Keywords: hsp90; geldanamycin; ischemia/reperfusion; Akt; JNK3; neuroprotectionASK1, apoptosis signal-regulating kinase 1; CCA, common carotid artery; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; EBSS, Earl's balanced salt solution; ECA, external carotid ar

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

The EDGE hypothesis: Epigenetically directed genetic errors in repeat-containing proteins (RCPs) involved in evolution, neuroendocrine signaling, and cancer

Keywords: Repeat-containing proteins (RCPs); Neuroendocrine signaling; Evolution; Cancer; Epigenetics; Trans-generational epigenetics; Endocrine disruptors; Hsp90; Trinucleotide repeats

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

Anti-heat shock protein 90β antibodies are detected in patients with multiple sclerosis during remission

Keywords: Autoantibodies; Cerebrospinal fluid; Hsp90; Multiple sclerosis; Remission; Western blot

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Resistance to geldanamycin-induced apoptosis in differentiated neuroblastoma SH-SY5Y cells

Keywords: SH-SY5Y; GA; Hsp90; RA; p53;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Studies on the role of HtpG in the tetrapyrrole biosynthesis pathway of the cyanobacterium Synechococcus elongatus PCC 7942

Keywords: HtpG; Hsp90; HemE; Uroporphyrinogen decarboxylase; Tetrapyrrole; Thylakoid membrane

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Hsp90—From signal transduction to cell transformation

Keywords: Hsp90; Heat shock protein; Molecular chaperone; ATPase; Genetic capacitor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of the HAP1 gene involves positive actions of histone deacetylases

Keywords: Transcriptional repression; Hap1; Histone deacetylase; DNA-binding; CGG triplet; Ssa; Hsp90; Molecular chaperone;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه