Keywords: عنصر حساس به هیپوکسی; Hb; haemoglobin; HIF; hypoxia-inducible factor; HRE; hypoxia-responsive element; Differential isoform expression; Oxygen homeostasis; Proteomics; Stress response; Transcriptomics;
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Keywords: عنصر حساس به هیپوکسی; HRE; hypoxia-responsive element; HIF-1; hypoxia-inducible factor-1; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; siRNA; small interfering RNA; AMPK; 5â²-adenosine monophosphate-activated protein kinase; PBS; phosphate buffered sal
Keywords: عنصر حساس به هیپوکسی; 3â²UTR; 3â² untranslated region; Ago2; Argonaute 2; CCN5; cysteine-rich 61/connective tissue growth factor/nephroblastoma overexpressed 5; ChIP; chromatin immunoprecipitation; CUL2; cullin2; DGCR8; Di George syndrome critical region 8; DMNT; DNA methylt
The Hypoxia Mimetic Protocatechuic Acid Ethyl Ester Inhibits Synaptic Signaling and Plasticity in the Rat Hippocampus
Keywords: عنصر حساس به هیپوکسی; 2-OG; 2-oxoglutarate; aCSF; artificial cerebrospinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AP-5; (2R)-amino-5-phosphonovaleric acid; CA1; Cornu Ammonis 1; DFO; desferrioxamine; DIV; days in vitro; DMOG; dimethyloxal
Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness
Keywords: عنصر حساس به هیپوکسی; Ac; acetylated; BH3; Bcl2 homology 3; CM-H2-DCFDA; 5-(and 6)-chloromethyl-2,7-dichlorodihydrofluorescein diacetate acetyl ester; CoCl2·6H2O; cobalt chloride hexahydrate; Cyt c; cytochrome c; DAPI; (4â²,6-Diamidino-2-phenylindole Dilactate; ERK; extracel
PIM kinase (and Akt) biology and signaling in tumors
Keywords: عنصر حساس به هیپوکسی; PIM kinases; Akt; Oncogenes; Cancer; Therapeutic resistance; AML; acute myeloid leukemia; AMPK; AMP activated protein kinase; CXCR-4; C-X-C chemokine receptor type 4; EGFR; epidermal growth factor receptor; EBV; Epstein-Barr virus; FLT3; FMS-like ty
Cloning and characterization of hypoxia-inducible factor-1 subunits from Ascaris suum - A parasitic nematode highly adapted to changes of oxygen conditions during its life cycle
Keywords: عنصر حساس به هیپوکسی; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH; basic helix-loop-helix; CAD; C-terminal activation domain; C-TAD; C-terminal transactivation domain; FIH; factor inhibiting HIF; HIF; hypoxia-inducible factor; HRE; hypoxia-responsive element; N-
Dendritic cell reprogramming by the hypoxic environment
Keywords: عنصر حساس به هیپوکسی; DC; dendritic cells; pO2; partial oxygen pressure; MP; mononuclear phagocytes; BM; bone marrow; MDPs; common macrophage/DC precursors; CDPs; common DC precursors; pre-DCs; DC-restricted precursors; pDCs; plasmacytoid DCs; H-iDCs; hypoxic immature DCs; H-m
Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors
Keywords: عنصر حساس به هیپوکسی; AP; alkaline phosphatase; HIF; hypoxia inducible factor; HRE; hypoxia-responsive element; VEGF; vascular endothelial growth factor; Drug development; Cancer; Transcription factor; Hypoxia; Angiogenesis; Glycolysis;
Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms
Keywords: عنصر حساس به هیپوکسی; BACK; BTB and C-terminal kelch; bHLH; basic helix-loop-helix; BTB; broad-complex/tramtrack/bric-a-brac; HIF; hypoxia-inducible factor; HRE; hypoxia-responsive element; KLHL20; kelch-like 20; ODD; oxygen-dependent degradation; PAS; PER-ARNT-SIM; pVHL;
Adaptive haemoglobin gene control in Daphnia pulex at different oxygen and temperature conditions
Keywords: عنصر حساس به هیپوکسی; Haemoglobin concentration; Hypoxia; Hypoxia-responsive element; Oxygen affinity; Proteomics; Subunit
Research ArticleHuman carbonyl reductase 1 upregulated by hypoxia renders resistance to apoptosis in hepatocellular carcinoma cells
Keywords: عنصر حساس به هیپوکسی; CBR1; carbonyl reductase 1; HCC; hepatocellular carcinoma cell; HRE; hypoxia-responsive element; SDR; short chain dehydrogenase/reductase; ONE; 4-oxonon-2-enal; HIF-1α; hypoxia inducible factor-1α; TACE; transarterial chemoembolization; HO-1; heme oxyge
Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury
Keywords: عنصر حساس به هیپوکسی; Vascular Endothelial Growth Factor; Tumor Necrosis Factor; ITF/TFF3; Nitric Oxide Synthase; CDAD; C difficile-associated disease; DMOG; dimethyloxaloylglycine; HIF-1; hypoxia-inducible factor-1; HIF-1α(Epâ/â); targeted epithelial HIF-1αâ/â knock
Adenovirus-mediated brain-derived neurotrophic factor expression regulated by hypoxia response element protects brain from injury of transient middle cerebral artery occlusion in mice
Keywords: عنصر حساس به هیپوکسی; Adenovirus vector; Hypoxia-responsive element; Brain-derived neurotrophic factor; Cerebral ischemia; Mouse
Hammerhead ribozyme targeting human hypoxia inducible factor-1α gene effectively attenuates HeLa xenograft tumors
Keywords: عنصر حساس به هیپوکسی; CMV; cytomegalovirus; DMEM; Dulbeco's modified eagle medium; HIF-l; hypoxia inducible factor l; HRE; hypoxia-responsive element; mRNA; messenger RNA; mRz; mutant ribozyme; PAS; Per/Arnt/Sim; PBS; phosphate buffer solution; PCR; polymerase chain reaction;
Three-dimensional cell organization leads to almost immediate HRE activity as demonstrated by molecular imaging of MG-63 spheroids using two-photon excitation microscopy
Keywords: عنصر حساس به هیپوکسی; Three-dimensional tumor spheroid; Two-photon excitation microscopy; Hypoxia-responsive element; Hypoxia-inducible factor-1; Hypoxia; GFP-reporter vector