6-Substituted quinolines as RORγt inverse agonists
Keywords: RORγt; Retinoic acid-related orphan nuclear receptor gamma t; Th17; IL-17;
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Imbalance of Th17 and Treg in peripheral blood mononuclear cells of active tuberculosis patients
Keywords: Active tuberculosis; Th17; Treg; IL-17; IL-10;
Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway
Keywords: PPPP; palmoplantar pustular psoriasis; NPPPP; non-pustular palmoplantar psoriasis; Psoriasis; Palmoplantar psoriasis; Palmoplantar pustular psoriasis; IL-17; IL-23; Skin biopsies;
IL-17 for therapy
Keywords: Psoriasis; Autoimmunity; IL-17; IL-17 receptor; IL-17 neutralizing monoclonal antibodies;
Serum IL-10, IL-17 and IL-23 levels as “bioumoral bridges” between dyslipidemia and atopy
Keywords: Atopy; Children; Dyslipidemia; IL-10; IL-17; IL-23;
HMGB1 redox during sepsis
Keywords: CBP; CREB-binding protein; DAMPs; damage-associated molecular patterns; G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte macrophage colony-stimulating factor; HK2; Human Kidney Proximal Tubule cells - type 2; HMGB1; high mobility group bo
Research articleCXCL13 regulates the trafficking of GluN2B-containing NMDA receptor via IL-17 in the development of remifentanil-induced hyperalgesia in rats
Keywords: CXCL13; CXCR5; IL-17; GluN2B; Remifentanil-induced hyperalgesia;
Expanding biological activities of Ts19 Frag-II toxin: Insights into IL-17 production
Keywords: Tityus serrulatus; Ts19 Frag-II; Biochemical parameters; Cytokines; IL-17; Proinflammatory;
Skin-infiltrating, interleukin-22-producing T cells differentiate pediatric psoriasis from adult psoriasis
Keywords: IL-17; IL-22; immunophenotype; pediatric psoriasis; psoriasis; BSA; body surface area; IFN-γ; interferon γ; IL; interleukin; TNF-α; tumor necrosis factor α; T regs; regulatory T cells; UCSF; University of California, San Francisco;
Aneurysmal subarachnoid hemorrhage lead to systemic upregulation of IL-23/IL-17 inflammatory axis
Keywords: IL-23; IL-17; Aneurysmal subarachnoid hemorrhage; Inflammation; Cytokines; Early brain injury;
Formula PSORI-CM01 inhibits the inflammatory cytokine and chemokine release in keratinocytes via NF-κB expression
Keywords: PSORI-CM01; formula PSORI-CM01; PCM01CS; serum contained PSORI-CM01; IMQ; imiquimod; PASI; Psoriasis Area Severity Index; IFN-γ; interferon-γ; HE; Hematoxylin and eosin; IL-6; interleukin 6; IL-8; interleukin 8; IL-12; interleukin 12; IL-17; interleukin
IL-23/Th17 targeted therapies in SAPHO syndrome. A case series
Keywords: SAPHO syndrome; IL-23; IL-17; Treatment; Ustekinumab; Secukinumab;
Evaluation of profile and functionality of memory T cells in pulmonary tuberculosis
Keywords: PBMC; peripheral blood mononuclear cells; IL-17; interleukin-17; IL-2; interleukin-2; IFN- ɣ; Interferon-gamma; TNF-α; tumor necrosis factor-alpha; Mtb; Mycobacterium tuberculosis; Mtb-Ags; antigens of the strain H37Rv of Mycobacterium tuberculosis; TB;
IL-17 axis accelerates the inflammatory progression of obese in mice via TBK1 and IKBKE pathway
Keywords: Obesity; IL-17; TBK1; Il-17; interleukin-17; TBK1; tank binding kinae-1; IKBKE; IκB kinase subunit epsilon;
CCAAT/Enhancer-binding protein β promotes pathogenesis of EAE
Keywords: C/EBPβ; Transcription factor; EAE; IL-17; Th17; IL-23R;
The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice
Keywords: Dimethyl fumarate (PubChem CID: 637568); FTY720 (PubChem CID: 107969); Nrf2; EAE; IL-17; IL-6;
Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin
Keywords: Curcumin; IL-17; Imiquimod; Inflammation; In vitro model; HaCaT; Psoriasis;
IL-17 contributes to the pathogenesis of obliterative bronchiolitis via regulation of M1 macrophages polarization in murine heterotopic trachea transplantation models
Keywords: OB; obliterative bronchiolitis; H&E; hematoxylin-eosin; HTT; heterotopic trachea transplantation; KO; knock-out; LPS; lipopolysaccharide; WT; wild-type; BMDMs; bone marrow-derived macrophages; IL-17; Macrophages; Obliterative bronchiolitis; Trachea transp
Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice
Keywords: UC; Ulcerative colitis; BJOE; Brucea javanica oil emulsion; SASP; Sulfasalazine; AZA; Azathioprine; TNF-α; Tumor necrosis factor-α; IL-1β; Interleukin-1β; IL-6; Interleukin-6; IL-8; Interleukin-8; IL-17; Interleukin-17; IFN-γ; Interferon-γ; MPO; mye
Shear stress inhibits IL-17A-mediated induction of osteoclastogenesis via osteocyte pathways
Keywords: IL-17; interleukin-17; OPG; osteoprotegerin; RANKL; receptor activator of nuclear factor κ-B ligand; TNF-α; tumor necrosis factor-α; BMM; bone marrow-derived macrophage; ERK; extracellular signal-regulated kinase; STAT3; signal transducer and activator
The therapeutic effects of Yongdamsagan-tang on autoimmune hepatitis models
Keywords: AIH; autoimmune hepatitis; IL-17; interleukin 17; Th17; Th17 cells; YST; Yongdamsagan-tang; GS; Gentiana scabra; TGF-β1; transforming growth factor-b; Col-a1(I); collagen type 1; α-SMA; a-smooth muscle actin; LPS; Escherichia coli lipopolysaccharide; MA
Trikatu, an herbal compound ameliorates rheumatoid arthritis by the suppression of inflammatory immune responses in rats with adjuvant-induced arthritis and on cultured fibroblast like synoviocytes via the inhibition of the NFκB signaling pathway
Keywords: Rheumatoid arthritis; Trikatu; Fibroblast-like synoviocytes; Inflammatory mediators; IL-17; NFкB;
An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis
Keywords: Epidermis; ichthyosis; inflammation; autosomal recessive congenital ichthyosis; congenital ichthyosiform erythroderma; lamellar ichthyosis; Netherton syndrome; epidermolytic ichthyosis; skin; IL-17; TNF-α; AD; Atopic dermatitis; AMP; Antimicrobial peptid
Levels of peripheral Th17 cells and serum Th17-related cytokines in patients with multiple sclerosis: A meta-analysis
Keywords: Multiple sclerosis; Th17 Cells; IL-17; IL-10;
Abnormal CD161+ immune cells and retinoic acid receptor-related orphan receptor γt-mediate enhanced IL-17F expression in the setting of genetic hypertension
Keywords: Hypertension; innate immune system; Toll-like receptor; retinoic acid receptor-related orphan receptor γt; digoxin; T cells; TH17; CD161; IL-17; spontaneously hypertensive rat; gene expression; nAChR; Nicotinic acetylcholinergic receptor; PE; Phycoeryt
β-Defensin 2 is a responsive biomarker of IL-17A-driven skin pathology in patients with psoriasis
Keywords: IL-17; psoriasis; secukinumab; β-defensin 2; biomarker; dermal interstitial fluid; microperfusion; psoriatic arthritis; ankylosing spondylitis; rheumatoid arthritis; multiple sclerosis; autoimmunity; AS; Ankylosing spondylitis; BD-2; β-Defensin 2; CD; C
Osteopontin inhibition of miR-129-3p enhances IL-17 expression and monocyte migration in rheumatoid arthritis
Keywords: OPN; IL-17; Osteoblasts; Arthritis; Rheumatoid arthritis; Osteoarthritis;
Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade
Keywords: Cytokines; IL-17; Neutrophils; MDSC; PD-1; Resistance;
Local and systemic Th17 immune response associated with advanced stage colon cancer
Keywords: Colorectal cancer; Inflammation; Th17; IL-17; Biomarkers;
Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue
Keywords: ConA; Concanavalin A; OA-5-HT; oleoyl serotonin; SA-5-HT; stearoyl serotonin; PA-5-HT; palmitoyl serotonin; AA-5-HT; arachidonoyl serotonin; AEA; arachidonoyl ethanolamide (anandamide); DHA; docosahexaenoic acid; DHA-5-HT; docosahexaenoyl serotonin; DHEA;
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt
Keywords: RORγt; Retinoic acid-related orphan nuclear receptor gamma t; Agonist; Neutral antagonist; Inverse agonist; Th17; IL-17;
Extracellular miR-145, miR-223 and miR-326 expression signature allow for differential diagnosis of immune-mediated neuroinflammatory diseases
Keywords: MicroRNAs; Multiple sclerosis; Neuromyelitis optica spectrum disorder; Neuropsychiatric systemic lupus erythematosus; Immune-mediated neuroinflammatory diseases; AQP4; aquaporin-4; CD47; cluster of differentiation 47; cDNA; complementary DNA; EDSS; expand
Nrf2 signaling pathway: Pivotal roles in inflammation
Keywords: ARE; antioxidant response element; CBP; cAMP-response-element-binding protein binding protein; COX-2; cyclooxygenase 2; Gclc; glutamate cysteine ligase catalytic subunit; Gclm; glutamate cysteine ligase regulatory subunit; GSH; glutathione; HO-1; heme oxy
Pathophysiology of IL-33 and IL-17 in allergic disorders
Keywords: IL-17; IL-33; Allergic diseases;
A possible role for IL-17 in Clarkson's disease
Keywords: Children; Clarkson's disease; IL-17; Systemic capillary leak syndrome;
IL-23/IL-17/G-CSF pathway is associated with granulocyte recruitment to the lung during African swine fever
Keywords: ASF; IL-17; IL-23; G-CSF; Granulocytes;
Myocardial fibrosis seen through the lenses of T-cell biology
Keywords: Foxp3; Forkhead box P3; IFN-γ; Interferon-gamma; IL-4; Interleukin-4; IL-5; Interleukin-5; IL-10; Interleukin-10; IL-13; Interleukin-13; IL-17; Interleukin-17; NOS2; Inducible Nitric Oxide Synthase; Teff; Effector T-cell; Th; T-helper cell; Treg; Regulat
Positive fungal quantitative PCR and Th17 cytokine detection in bronchoalveolar lavage fluids: Complementary biomarkers of hypersensitivity pneumonitis?
Keywords: Hypersensitivity pneumonitis; Interstitial lung disease; Bronchoalveolar fluid; IL-17; IL-23; Fungal QPCR; Eurotium amstelodami; Wallemia sebi;
Correlation between nerve growth factor and tissue expression of IL-17 in leprosy
Keywords: Nerve grown factor; IL-17; Cytokines; Immunopathology
Increased IL-17 and 22 mRNA expression in pediatric patients with otitis media with effusion
Keywords: Otitis media with effusion (OME); IL-17; IL-22;
Increased RUNX1 expression in patients with immune thrombocytopenia
Keywords: Immune thrombocytopenia; Runt-related transcription factor 1; Retinoic acid receptor-related orphan receptor-γt; IL-17;
Short communicationPredominance of Th1 response, increase of megakaryocytes and Kupffer cells are related to survival in Trypanosoma cruzi infected mice treated with Lycopodium clavatum
Keywords: Trypanosoma cruzi; Lycopodium clavatum; Megakaryocytes; Kupffer cells; Th1 response; Th1; T helper cell type 1; Th2; T helper cell type 2; TNF-α; tumor necrosis factor alpha; IFN-γ; Interferon gama; IL-10; Interleukin 10; IL-4; Interleukin 4; IL-17; Int
Research paperRole of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines
Keywords: Th17 cells; Leishmania; Vaccine; IL-17;
Brief CommunicationInterleukin 17 signaling drives Type I Interferon induced proliferative crescentic glomerulonephritis in lupus-prone mice
Keywords: Systemic lupus erythematosus; Type I Interferon; IL-17; Crescentic glomerulonephritis; Lupus;
Relation between serum IL-17 level and risk of osteoporotic fracture in premenopausal rheumatoid arthritis patients: Clinical, radiological and laboratory studies
Keywords: IL-17; FRAX; Osteoporotic fractures; Rheumatoid arthritis; Premenopausal females
CD25 signaling regulates the function and stability of peripheral Foxp3+ regulatory T cells derived from the spleen and lymph nodes of mice
Keywords: Treg; CD25; Foxp3; IL-17; IR;
IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease
Keywords: EAE; experimental autoimmune encephalomyelitis; HCV; hepatitis C virus; IRF; interferon regulatory factor; RORγ; retinoic acid receptor-related orphan receptor gamma; CD8+; IL-17; Tc17; Inflammation; Disease;
Emerging roles of the Th17/IL-17-axis in glomerulonephritis
Keywords: T-helper 17; IL-17; Glomerulonephritis;
Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice via Jak3/Stat3 signaling pathway
Keywords: Psoriasis; Th17; IL-17; Imiquimod; Astilbin; Inflammation;
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties
Keywords: RORc; RORγ; Inverse agonist; IL-17; PBMCs; Oxa-sultam