Keywords: Allergy; immunology; innate; inflammation; food allergy; asthma; mast cell; eosinophil; ozone; IL-33; extracellular vesicles; AERD; Aspirin-exacerbated respiratory disease; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; DP1;
مقالات ISI (ترجمه نشده)
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Keywords: Respiratory syncytial virus; helminths; Heligmosomoides polygyrus; type I interferon; microbiome; cDC; Conventional dendritic cell; HES; Heligmosomoides polygyrus excretory-secretory; IL-4R; IL-4 receptor; ISG; Interferon-stimulated gene; mCRAMP; Murine c
Keywords: Biomarkers; Checkpoint molecules; Cytokines; Glioblastoma; Immunotherapy; Microbiome; Mutational landscape; CB; Cintredekin besudotox; CNS; Central nervous system; CTLA-4; Cytotoxic T lymphocyte antigen 4; CyTOF; Cytometry by time-of-flight; EGFR; Epiderm
Keywords: Food allergy; microbiome; microbiota; regulatory TÂ cells; tolerance; anaphylaxis; IgE; 16S rDNA; IL-4 receptor; Foxp3; Forkhead box protein 3; GF; Germ free; HC-AN; Hierarchical clustering-average-neighbor; IL-4R; IL-4 receptor; iTreg; Induced regulatory
The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma
Keywords: Allergic asthma; Notch signaling; Gata3; TH2 immunity; house dust mite; recombination signal-binding protein for IgJκ region; stapled α-helical peptide derived from mastermind-like 1; BAL; Bronchoalveolar lavage; BHR; Bronchial hyperreactivity; DC; De
Interleukin-13/interleukin-4 receptor pathway is crucial for production of Sda-sialomucin in mouse small intestinal mucosa by Nippostrongylus brasiliensis infection
Keywords: Mucin; Il-13; Il-4R; Nematode; Nippostrongylus brasiliensis; Sda antigen;
IL-4R suppresses airway inflammation in bronchial asthma by inhibiting the IL-4/STAT6 pathway
Keywords: Bronchial asthma; Airway inflammation; IL-4; STAT6; IL-4R;
Interleukin-4 receptor-targeted delivery of Bcl-xL siRNA sensitizes tumors to chemotherapy and inhibits tumor growth
Keywords: Bcl-xL; BPEI-SPION; Chemotherapy; IL-4R; siRNA;
Mechanisms of allergy and clinical immunologyRhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation
Keywords: RhoA; T-cell metabolism; glycolysis; TH2 differentiation; allergic airway inflammation; BAL; Bronchoalveolar lavage; BrdU; 5-Bromo-2-deoxyuridine; CD62L; CD62 ligand; 2-DG; 2-Deoxy-D-glucose; ECAR; Extracellular acidification rate; IL-4R; IL-4 receptor; m
IL-4 production by group 2 innate lymphoid cells promotes food allergy by blocking regulatory T-cell function
Keywords: Anaphylaxis; food allergy; IL-4; IL-13; IL-33; group 2 innate lymphoid cells; innate lymphoid cells; nuocytes; mast cells; regulatory TÂ cells; oral tolerance; DT; Diphtheria toxin; DTR; Diphtheria toxin receptor; eGFP; Enhanced green fluorescent protein;
Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma
Keywords: Hematopoietic progenitor cells; thymic stromal lymphopoietin; asthma; EoP; Eosinophil lineage-committed progenitor; HPC; Hematopoietic progenitor cell; IL-4R; IL-4 receptor; IL-13R; IL-13 receptor; PE; Phycoerythrin; TSLP; Thymic stromal lymphopoietin;
Differential requirements of MyD88 and TRIF pathways in TLR4-mediated immune responses in murine B cells
Keywords: Aicda; activation-indeced cytidine deaminase; CSR; class switch recombination; IL-4R; IL-4 receptor; MD-2; myeloid differentiation protein-2; MPLA; monophosphoryl lipid A; RP105; radioprotective 105; TI; T cell-independent; TIR; Toll/IL-1R; TNP; trinitrop
100Â Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology
Keywords: Allergens; allergy; function; structure; cross-reactivity; x-ray crystallography; GFP; Green fluorescent protein; IL-4R; IL-4 receptor; IUIS; International Union of Immunological Societies; MBP; Maltose-binding protein; TLR; Toll-like receptor; WHO; World
Significant association of interleukin-4 gene intron 3 VNTR polymorphism with susceptibility to knee osteoarthritis
Keywords: IL-4; interleukin 4; OA; osteoarthritis; PCR; polymerase chain reaction; RFLP; restriction fragment length polymorphism; VNTR; variable number tandem repeat; IL-4R; interleukin-4 receptor; RA; rheumatoid arthritis; ESRD; end-stage renal disease; SLE; syst
Reviews and feature articleA molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease
Keywords: Thymic stromal lymphopoietin; IL-4; IL-13; receptors; cytokines; TH2; allergy; asthma treatment; FNIII; Fibronectin III; IL-4R; IL-4 receptor; IL-7R; IL-7 receptor; IL-13R; IL-13 receptor; JAK; Janus kinase; MMP; Matrix metalloproteinase; STAT; Signal tra
Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: AÂ randomized trial
Keywords: IL-13; IL13Rα1; IL13Rα2; efficacy; safety; pharmacokinetics; pharmacodynamics; ACQ; Asthma Control Questionnaire; ADA; Anti-drug antibody; AE; Adverse event; ECLIA; Electrochemiluminescence immunoassay; Feno; Fraction of exhaled nitric oxide; FPE; Fluti
Research paperEffect of hay dust extract and cyathostomin antigen stimulation on cytokine expression by PBMC in horses with recurrent airway obstruction
Keywords: RAO; Hay dust; Cyathostomins; Warmblood horses; IL-4R; IL-10;
ReviewLinking surfactant protein SP-D and IL-13: Implications in asthma and allergy
Keywords: AHR; airway hyper-responsiveness; Afu; Aspergillus fumigatus; IL; interleukin; SP; surfactant protein; Th; T helper; MCh; methacholine; IgE; immunoglobulin E; LTA; lymphotoxin A; IL-4R; interleukin 4 receptor; KO; knockout, NFAT; MMP; matrix metalloprotei
Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis
Keywords: Food allergy; epicutaneous sensitization; IgE; mast cells; anaphylaxis; AD; Atopic dermatitis; CAE; Chloroacetate esterase; CT; Cholera toxin; CTMC; Connective tissue mast cell; IL-4R; IL-4 receptor; MC; Mast cell; MLN; Mesenteric lymph node; mMCP-1; Mous
Association of IL-4 receptor gene polymorphisms with high density lipoprotein cholesterol
Keywords: BMI; body mass index; BUN; blood urea nitrogen; CRE; creatinine; HDL-C; high density lipoprotein-cholesterol; IL-4; interleukin-4; IL-4R; IL-4 receptor; IL-4Rα; interleukin-4 receptor α chain; LDL; low density lipoproteins; PCR; polymerase chain reactio
Dendritic cells and alveolar macrophages mediate IL-13-induced airway inflammation and chemokine production
Keywords: Asthma; airway; macrophage; chemokines; inflammation; IL-13; IFN-γ; CD11b; dendritic cell; macrophage-derived chemokine; thymus and activation-regulated chemokine; AHR; Airway hyperreactivity; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; DC-SIGN; D
Immune response modifiers in the treatment of asthma: AÂ PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology
Keywords: Immune response modifiers; monoclonal antibodies; asthma; allergic diseases; APC; Antigen-presenting cell; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells (also known as DP2); FDA; US Food and Drug Administration; Feno; Fraction
Mechanisms of allergy and clinical immunologyIgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling
Keywords: Food allergy; IL-4; tolerance; anaphylaxis; IgE; CT; Cholera toxin; DNP; Dinitrophenyl; FITC; Fluorescein isothiocyanate; HRP; Horseradish peroxidase; IL-4R; IL-4 receptor; LPF; Low-power field; mMCP-1; Murine mast cell protease 1; OVA; Ovalbumin; SEB; St
IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
Keywords: ChIP; chromatin immunoprecipitation; CYP; cytochrome P450; Elk1; member of ETS oncogene family; FOXO1; forkhead box protein O1; IL-4; interleukin-4; IL-4R; interleukin-4 receptor; IRS; insulin receptor substrate; JAK; janus protein kinase; MAPK; mitogen-a
Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study
Keywords: IgE; respiratory tract infection; wheeze; asthma; infancy; ARI; Acute respiratory illness; HDM; House dust mite; IL-4R; IL-4 receptor; OR; Odds ratio; SLRI; Severe lower respiratory tract illness;
In vivo regulation of the allergic response by the IL-4 receptor α chain immunoreceptor tyrosine-based inhibitory motif
Keywords: IL-4 receptor; IL-4; IL-13; immunoreceptor tyrosine-based inhibitory motif; Src homology 2 domain-containing protein tyrosine phosphatase 1; IgE; allergic airway inflammation; asthma; AHR; Airway hyperresponsiveness; alum; Aluminum potassium phosphate;
Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides
Keywords: DTT; dithiothreitol; GSH; reduced glutathione; IL-4; interleukin-4; IL-4R; interleukin-4 receptor; LPS; lipopolysaccharide; NAC; N-acetylcysteine; NEM; N-ethylmaleimide; PDI; protein disulfide isomerase; Th; T-helper; Trx1; thioredoxin 1; TR; thioredoxin
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung
Keywords: TH2 cytokines; microarrays; allergic asthma; mouse; AHR; Airway hyperresponsiveness; GTPase; Guanosine triphosphatase; HDM; House dust mite; IL-4R; IL-4 receptor; IL-13R; IL-13 receptor; RWP; Ragweed pollen; STAT; Signal transducer and activator of transc
Enhanced CCL26 production by IL-4 through IFN-γ-induced upregulation of type 1 IL-4 receptor in keratinocytes
Keywords: Keratinocytes; IL-4; IFN-γ; IL-4R; CCL26
Binding characterization of the interleukin-13 signaling complex and development of a ternary time-resolved fluorescence resonance energy transfer assay
Keywords: IL-13; IL-13Rα1; IL-4R; Binary complex; Ternary complex; Signaling complex; Asthma; Surface plasmon resonance; Time-resolved fluorescence resonance energy transfer;
IL-4 induces IL-13–independent allergic airway inflammation
Keywords: Airways hyperresponsiveness; eosinophil; goblet cell; IL-4; IL-4 receptor; IL-13; mouse; mucusAHR, Airways hyperresponsiveness; APF, Ascaris species pseudocoelomic fluid; BAL, Bronchoalveolar lavage; IL-4C, Anti–IL-4 mAb that is saturated with IL-4; IL-4R
Circulating levels of the interleukin (IL)-4 receptor and of IL-18 in patients with Plasmodium falciparum malaria
Keywords: Malaria; Plasmodium falciparum; IL-4R; IL-18;
SHP-1 regulates STAT6 phosphorylation and IL-4-mediated function in a cell type-specific manner
Keywords: IL-4 receptor expression; Signaling; Viable motheaten; IL-4R; IL-4 receptor; SHP-1; SH2 domain-containing protein tyrosine phosphatase-1; mev/mev; Viable motheaten mice; STAT6; Signal transducer and activator of transcription; Jak; Janus kinase;