Keywords: Ang-1; Angiopoietin1; Ang-2; Angiopoietin-2; BDNF; Brain-Derived Neurotrophic Factor; bFGF; basic Fibroblast Growth Factor; CRP; C-Reactive Protein; DAS-II; Differential Ability Scales-II; EPO; Erythropoietin; ICAM-1; Intercellular Adhesion Molecule â
مقالات ISI (ترجمه نشده)
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Keywords: Asthma; chronic obstructive pulmonary disease; asthma and chronic obstructive pulmonary disease heterogeneity; inflammatory profiles; microbiome abundances; phylum and genus levels; factor and cluster analyses; COPD; Chronic obstructive pulmonary disease
Keywords: 7AAD; 7-aminoactinomycin D; αSMA; alpha smooth muscle actin; AKT; protein kinase B; ALK; activin receptor-like kinase; Ang; angiopoietin; Ang II; angiotensin II; BCRP1; breakpoint cluster region pseudogene; bFGF; basic fibroblast growth factor; C1P; cera
Keywords: Proinflammatory cytokines; Schizophrenia; Lymphocytes; IL-1β; IL-6; TNF-α; IL-1R1; IL-1R2; IL-1RA; IL-6R; Gp130; TNFR1; TNFR2;
Keywords: ECM; extracellular matrix; EGF; epidermal growth factor; EOC; epithelial ovarian cancer; G-CSF; granulocyte colony-stimulating factor; GP130; glycoprotein 130; IL; interleukin; JAK; Janus kinase; LIF; leukemia inhibitory factor; MAPK; mitogen-activated pr
Keywords: Angiogenesis; Antiangiogenic agents; Angiogenic cytokines/peptides; EC; endothelial cells; VEGF; vascular endothelial growth factor; VEGF Receptor; VEGFR; FGF; fibroblast growth factor; EGF; epidermal growth factor; epidermal growth factor receptor; EGFR;
IL-1β/IL-6 network in the tumor microenvironment of human colorectal cancer
Keywords: IL; interleukin; IL-1βR1; IL-1β receptor type 1; IL-6R; IL-6 receptor; IHC; immunohistochemistry; DIF; double immunofluorescence; CRC; colorectal carcinoma; COX2; cyclooxygenase-2; TNM; tumor/node/metastasis; PCR; polymerase chain reaction; Interleukin-
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
Keywords: BALF; bronchoalveolar lavage fluid; CAC; colitis-associated cancer; CAF; cancer associated fibroblast; ccRCC; clear cell renal cell carcinoma; CLC; cardiotrophin-like cytokine; CML; chronic myeloid leukemia; CNTF; ciliary neurotrophic factor; COPD; chroni
Role of the IL-6-Receptor expression in CD14+ monocytes in modulating sleep in patients with bipolar disorder
Keywords: Bipolar disorder; Sleep; IL-6R; Biomarker, Circadian rhythms;
Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review
Keywords: AAV; antineutrophil cytoplasmic antibody associated vasculitis; ACE; angiotensin-converting enzyme; Agt; angiotensin; ANCA; antineutrophil cytoplasmic antibody; AT1R; angiotensin II receptor type 1; AT2R; angiotensin II receptor type 2; CCL2; chemokine C-
Association of genetic variations in IL-6/IL-6R pathway genes with gastric cancer risk in a Chinese population
Keywords: IL-6; Interleukin-6; IL-6R; Interleukin-6 receptor; SNPs; Single nucleotide polymorphisms; H. pylori; Helicobacter pylori; HWE; Hardy-Weinberg equilibrium; OR; odds ratios; CI; confidence intervals; Gastric cancer; Interleukin-6 (IL-6); Interleukin-6 rece
miR-451 inhibits cell growth, migration and angiogenesis in human osteosarcoma via down-regulating IL 6R
Keywords: miR-451; Growth; Migration; Angiogenesis; IL-6R; Osteosarcoma;
Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals
Keywords: Tumor-associated macrophages; Hypoxia; Tumor microenvironment; IL-6R; STAT3;
Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice
Keywords: ANOVA; analysis of variance; ACSF; artificial cerebral-spinal fluid; CNS; central nervous system; DNA; deoxyribonucleic acid; ERK; extracellularly regulated kinase; fEPSP; field excitatory postsynaptic potential; HFS; high-frequency stimulation; I/O; inpu
The shedding protease ADAM17: Physiology and pathophysiology
Keywords: ADAM proteases; ADAM17; IL-6R; IL-6 trans-signaling; Shedding; EGF receptor; iPS cell system;
IL-6 Polymorphism and Susceptibility to Keloid Formation in a Japanese Population
Keywords: CI; confidence interval; IL-6R; IL-6 receptor; OR; odds ratio; SNP; single nucleotide polymorphisms;
Research reportThe effect of some immunomodulatory and anti-inflammatory drugs on Li-pilocarpine-induced epileptic disorders in Wistar rats
Keywords: BBB; blood brain barrier; CA; catecholamine; IFN-γ; interferon-gamma; IL; interleukin; IL-1R; interleukin-1 receptor; IL-1Ra; interleukin-1 receptor antagonist; IL-6R; IL-6 receptor; IP; intraperitoneal; NF-kB; nuclear factor kappaB; NMDA; N-methyl-d-asp
Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains
Keywords: CD82; 4F9; VEGF; VGFR2; Angiogenesis; BSA; bovine serum albumin; EC; endothelial cell; HUVEC; human umbilical vein endothelial cell; IL-6; interleukin-6; IL-6R; interleukin-6 receptor; mAb; monoclonal antibody; RTK; receptor tyrosine kinase; shCD82; shRNA
A soluble form of the interleukin-6 family signal transducer gp130 is dimerized via a C-terminal disulfide bridge resulting from alternative mRNA splicing
Keywords: Interleukin-6; IL-6R; Gp130; Sgp130; Trans-signaling;
Integrative proteomics and transcriptomics revealed that activation of the IL-6R/JAK2/STAT3/MMP9 signaling pathway is correlated with invasion of pituitary null cell adenomas
Keywords: Pituitary adenomas; Null cell adenomas; Invasion; IL-6R; JAK2; STAT3;
Baseline serum interleukin-6 to interleukin-2 ratio is associated with the response to seasonal trivalent influenza vaccine in solid organ transplant recipients
Keywords: AE; adverse event; CI; confidence interval; CV; coefficient of variation; GC; germinal center; HA; hemagglutinin; HAI; hemagglutination inhibition; IQR; interquartile range; ID; intradermal; IFN; interferon; IL; interleukin; IL-6R; interleukin-6 receptor;
Systems biology of IL-6, IL-12 family cytokines
Keywords: Systems biology; Mathematical modeling; IL-6-type cytokines; Quantitative analyses; Epo; erythropoietin; gp; glycoprotein; hESC; human embryonic stem cells; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; HGF; hepatocyte growth f
Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation
Keywords: Tocilizumab; MR16-1; sgp130-Fc; eosinophils; neutrophils; IL-17; γδ T cell; allergy; endotype; AHR; Airway hyperreactivity; BALF; Bronchoalveolar lavage fluid; HDM; House dust mite; IL-6R; IL-6 receptor; LTA; Lipoteichoic acid; mIL-6R; Membrane-bound IL
Sex differences in the relationship of IL-6 signaling to cancer cachexia progression
Keywords: IL-6r; STAT3; SOCS3; Skeletal muscle; ApcMin/+;
ReviewTargeting FcRn for the modulation of antibody dynamics
Keywords: Abdeg; antibodies that enhance IgG degradation; CDR; complementarity determining region; Epo; erythropoietin; HMEC; human microvasculature-derived endothelial cells; ITP; idiopathic thrombocytopenic purpura; IC; immune complex; IL-6; interleukin-6; IL-6R;
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases
Keywords: IL-6 trans-signaling; IL-6R; SNP; ADAM17; Limited proteolysis;
A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis
Keywords: Atopic dermatitis; persistent atopic dermatitis; prognosis; inflammation; soluble IL-6 receptor; single nucleotide polymorphism; longitudinal study; population-based cohort; candidate association study; genetic risk factor; AD; Atopic dermatitis; ALSPAC;
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
Keywords: IL-6; IL-6R; ILK; Osteosarcoma; Migration
Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: Possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes
Keywords: Interleukin-6; IL-6R; Developmental neurotoxicity; Learning; Social behavior; Neuroinflammation; Oligodendroglia; Myelin; Postnatal inflammation
The IL6R variation Asp358Ala is a potential modifier of lung function in subjects with asthma
Keywords: Soluble IL-6 receptor; IL-6; asthma; pulmonary lung function; severe asthma; IL-6 transsignaling; genetic variation; single nucleotide polymorphism rs2228145; ATS; American Thoracic Society; BAL; Bronchoalveolar lavage; CSGA; Collaborative Study on the Ge
The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
Keywords: ADAM17; A Disintegrin And Metalloprotease 17; TNF-α; Tumor Necrosis Factor-α; IL-6R; interleukin-6 receptor; IL-1RII; interleukin-1 receptor type II; EGF; Epidermal Growth Factor; MPD; membrane-proximal domain; PMA; phorbol 12-myristate 13-acetate; GPI;
Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130
Keywords: Fugu; Takifugu rubripes; IL-6R; gp130; IgM; B-cell
Characterisation, expression and ontogeny of interleukin-6 and its receptors in zebrafish (Danio rerio)
Keywords: Interleukin-6; IL-6; Zebrafish; Danio rerio; Inflammation; Ontogeny; IL-6R; Gp130;
Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain
Keywords: ADAM17; a disintegrin and metalloprotease 17; TNFα; tumor necrosis factor α; IL-6R; interleukin-6 receptor; DN-ADAM17; dominate-negative ADAM17; GPI; glycosylphosphatidylinositol; Mef; mouse embryonic fibroblasts; ADAM17; Metalloprotease; Metzincins; EG
Role of Notch and its oncogenic signaling crosstalk in breast cancer
Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-
Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist
Keywords: Pancreatitis; Pain; Mechanisms; Interleukin-6; CGRP; calcitonin gene-related peptide; DBTC; dibutyltin dichloride; DRG; dorsal root ganglia; IL-6R; interleukin-6 receptor; TB-2-081; 3-O-formyl-20R,21-epoxyresibufogenin;
Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice
Keywords: IL-6; interleukin-6; IL-6R; interleukin-6 receptor; TNF-α; tumor necrosis factor-alpha; IL-1β; interleukin-1β; KC; keratinocyte-derived chemokine; TNFR1â/â; TNF receptor type 1 knockout; IL-1ra; IL-1 receptor antagonist; JAK; Janus kinases; MAPK; m
IL-6R distribution in normal human and cynomolgus monkey tissues
Keywords: IL-6R; Normal human and monkey tissues; Immunohistochemistry; Tocilizumab; Tissue cross-reactivity study
The effects of IL-6 on CD4 T cell responses
Keywords: IL-6; IL-6R; CD4 T cell differentiation; T helper response; Th1/Th2/Th17; IL-21; Autoimmune disease; Allergic airway inflammation
Early effects of tocilizumab on bone and bone marrow lesions in a collagen-induced arthritis monkey model
Keywords: Rheumatoid arthritis; Collagen-induced arthritis model; IL-6; IL-6R; Tocilizumab; Osteoclasts; Osteoblast/stromal cells; RANKL; RANK; Reticulum fibers
Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis
Keywords: IL-6; IL-6R; Autoimmune orchitis; Germ cell apoptosis; Testicular macrophages
Colitis in mice lacking the common cytokine receptor γ chain is mediated by IL-6-producing CD4+ T cells
Keywords: CRγ; common cytokine receptor γ chain; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence-activated cell sorter; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IFN; interferon; IL; interleukin; IL-6R; interl