Keywords: IMQ; imiquimod; KO; knockout;
مقالات ISI (ترجمه نشده)
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Keywords: SC; subcutaneous; OA-NO2; nitro oleic acid; ACD; allergic contact dermatitis; CHS; contact hypersensitivity; LNO2; nitro linoleic acid; CLA-NO2; conjugated nitro linoleic acid; PPAR-γ; peroxisome proliferator-activated receptor-γ; Nrf2; nuclear factor E
Keywords: CXCL; CXC chemokine ligand; CM; conditioned medium; IMQ; imiquimod; LN; lymph node; WT; wild-type;
Keywords: IMQ; imiquimod; TLR; toll-like receptor;
Keywords: AD; atopic dermatitis; α2HS-GP; alpha-2-HS-glycoprotein; CCL20; C-C motif ligand 20; CCR2; C-C chemokine receptor type 2; CRP; C-reactive protein; CYA; ciclosporin; DC; dendritic cells; Dkk-1; dickkopf-related protein 1; dMVECs; dermal microvascular
Keywords: APC; antigen presenting cell; DLS; dynamic light scattering; PFA; paraformaldehyde; COX; cycloxygenase; LOX; lipoxygenase; LPS; lipo poly saccharide; FBS; fetal bovine serum; IMQ; imiquimod; SOD; superoxide dismutase; MDA; malon di-aldehyde; GSH; glutathi
Keywords: ASC; adipose-derived stromal cell; IMQ; imiquimod; FBs; fibroblasts; MSC; mesenchymal stem cell; BM; bone marrow;
Keywords: Sensory nerves; Transient receptor potential channels; Neuropeptides; Skin inflammation; Peripheral vasculature; ATP; adenosine triphosphate; CFA; Complete Freund's Adjuvant; CGRP; calcitonin gene related peptide; CLR; calcitonin receptor-like receptor; C
Resident and monocyte-derived Langerhans cells are required for imiquimod-induced psoriasis-like dermatitis model
Keywords: DCs; dendritic cells; dDCs; dermal dendritic cells; DT; diphtheria toxin; DTA; diphtheria toxin subunit A; DTR; diphtheria toxin receptor; huLangerin; human Langerin; IMQ; imiquimod; LCs; Langerhans cells; mLCs; monocyte-derived Langerhans cells; rLCs; re
The expression of mCTLA-4 in skin lesion inversely correlates with the severity of psoriasis
Keywords: CTLA4; Cytotoxic T lymphocyte antigen-4; sCTLA-4; soluble Cytotoxic T lymphocyte antigen-4; mCTLA-4; membrane Cytotoxic T lymphocyte antigen-4; IOD; Integrated option density; IMQ; Imiquimod; PASI; psoriasis area and severity index; Treg; regulatory T; CT
How Effective Is Tacrolimus in the Imiquimod-Induced Mouse Model of Psoriasis?
Keywords: IMQ; imiquimod; TAC; tacrolimus;
Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways
Keywords: Resolvin D1; Keratinocyte; Psoriasis; Inflammation; MAPKs; Boc; tert-butoxycarbonyl Met-Leu-Phe peptide; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-17; interleukin-17; IL-22; interleukin-22; IL-23; interleukin-23; IMQ; imiquimod; MAPKs; mitogen-a
Diarylheptanoid from rhizomes of Curcuma kwangsiensis (DCK) inhibited imiquimod-induced dendritic cells activation and Th1/Th17 differentiation
Keywords: APCs; antigen presenting cells; CCL; chemokine (CC motif) ligand; CCR; CC chemokine receptor type; DAPI; 40,6-diamidino-2-phenylindole; DCK; diarylheptanoid from Curcuma kwangsiensis; DCs; dendritic cells; ERK; extracellular signal-regulated kinase; GM-CS
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-α/IFN-γ-induced inflammatory response in keratinocytes and T cell-derived IL-17
Keywords: SAHH; S-adenosyl-l-homocysteine hydrolase; IMQ; imiquimod; KC; keratinocytes; IL; interleukin; ICAM-1; intercellular adhesion molecule-1; EGFR; epidermal growth factor receptor; MAPKs; mitogen activated protein kinases; ERK; extracellular signal-regulated
Topically applied azaphenothiazines inhibit experimental psoriasis in mice
Keywords: TNF α; tumor necrosis factor α; IL; interleukin; LPS; lipopolysaccharide; IMQ; imiquimod; KERTr; human skin keratinocyte cell line; CXCL; C-X-C motif ligand; poly(I:C); polyinosinic:polycytidylic acid; LF; lipofectamine; Psoriasis; Mice; Azaphenothiazin
Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation
Keywords: CH; contact hypersensitivity; IL-36R; IL-36 receptor; KC; keratinocyte; KD; knock-down; KO; knock-out; IMQ; imiquimod; Reg1; regnase-1;
Lack of Galanin Receptor 3 Alleviates Psoriasis by Altering Vascularization, Immune Cell Infiltration, and Cytokine Expression
Keywords: GAL; galanin; GAL2-KO; GAL2-R knockout mouse; GAL3-KO; GAL3-R knockout mouse; GAL2-R; galanin receptor 2; GAL3-R; galanin receptor 3; IMQ; imiquimod; KO; knockout; MPO; myeloperoxidase; TNF-α; tumor necrosis factor-α; WT; wild-type;
ITK and RLK Inhibitor PRN694 Improves Skin Disease in Two Mouse Models of Psoriasis
Keywords: IMQ; imiquimod; Th; T helper;
TRPA1 Acts in a Protective Manner in Imiquimod-Induced Psoriasiform Dermatitis in Mice
Keywords: IMQ; imiquimod; KO; knockout; RTX; resiniferatoxin; TNF-α; tumor necrosis factor-α; TLR; toll-like receptor; TRPA1; transient receptor potential ankyrin 1; TRPV1; transient receptor potential vanilloid 1; WT; wild type;
Exacerbation and Prolongation of Psoriasiform Inflammation in Diabetic Obese Mice: A Synergistic Role of CXCL5 and Endoplasmic Reticulum Stress
Keywords: ER; endoplasmic reticulum; IMQ; imiquimod; PA; palmitic acid;
Skin-Specific CD301b+ Dermal Dendritic Cells Drive IL-17âMediated Psoriasis-Like Immune Response in Mice
Keywords: BM; bone marrow; cDC; conventional dendritic cell; DC; dendritic cell; DT; diphtheria toxin; DTR; diphtheria toxin receptor; FLT3L; FMS-like tyrosine kinase 3 ligand; IMQ; imiquimod; LC; Langerhans cell;
CD100-Plexin-B2 Promotes the Inflammation in Psoriasis by Activating NF-κB and the Inflammasome in Keratinocytes
Keywords: AD; atopic dermatitis; IMQ; imiquimod; mCD100; membrane-bound CD100; qRT-PCR; quantitative real-time reverse transcriptase-PCR; sCD100; soluble CD100; siRNA; small interfering RNA; Th; TÂ helper;
Effects of Depilation Methods on Imiquimod-Induced Skin Inflammation in Mice
Keywords: HF; hair follicle; IF; infundibulum; IFE; interfollicular epidermis; IMQ; imiquimod;
Hepatitis C virus inhibits CD4 T cell function via binding to Toll-like receptor 7
Keywords: TLR7; CD4; HCV; IRS661; Imiquimod; TLR-7; Toll-like receptor 7; ssRNA; single stranded RNA; DC; dendritic cells; HCVcc; culture-derived hepatitis C virus; IFNγ; interferon gamma; ORNs; RNA oligonucleotides; HCV; hepatitis C virus; IMQ; imiquimod; PBMC; p
Role of thymic B cells in the development of thymus-derived regulatory T cell in vitro
Keywords: Thymic B cells; IMQ; LPS; nTregs; Costimulatory molecules; MHC II;
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase
Keywords: iNOS; inducible nitric oxide synthase; NOX; NADPH oxidase; BSO; Buthionine sulfoximine; NAC; N-acetyl cysteine; DPI; diphenyliodonium; IMQ; imiquimod; Psoriasis; Kidney; NADPH oxidase; iNOS; Oxidative stress;
Formula PSORI-CM01 inhibits the inflammatory cytokine and chemokine release in keratinocytes via NF-κB expression
Keywords: PSORI-CM01; formula PSORI-CM01; PCM01CS; serum contained PSORI-CM01; IMQ; imiquimod; PASI; Psoriasis Area Severity Index; IFN-γ; interferon-γ; HE; Hematoxylin and eosin; IL-6; interleukin 6; IL-8; interleukin 8; IL-12; interleukin 12; IL-17; interleukin
Psoriatic inflammation causes hepatic inflammation with concomitant dysregulation in hepatic metabolism via IL-17A/IL-17 receptor signaling in a murine model
Keywords: IL-17RC; IL-17 receptor C; iNOS; Inducible nitric oxide synthase; NFκB; Nuclear factor-kappa B; IMQ; Imiquimod; Psoriatic inflammation; Nuclear factor-kappa B; IL-17A; Liver; IL-17 receptor;
Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model
Keywords: ILC; innate lymphoid cells; MAIT cell; mucosal associated invariant T cell; IMQ; imiquimod; TLR7; Toll-like receptor; TPA; tumor promoter 12-O-tetradecanoylphorbol-13-acetate; DN αβ T cells; αβ-TCR+ CD4CD8 double negative T cells; RORγt; retinoic aci
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17
Keywords: ARE; antioxidant responsive element; ChIP; chromatin immunoprecipitation; EdU; 5-ethynyl-2â²-deoxyuridine; IMQ; imiquimod; K; keratin; pNrf2; phosphorylated Nrf2; siRNA; small interfering RNA; TNF-α; tumor necrosis factor-α;
Imiquimod induced ApoE-deficient mice might be a composite animal model for the study of psoriasis and dyslipideamia comorbidity
Keywords: ApoE; apolipoprotein E; IMQ; imiquimod; TC; total cholesterol; TG; triglycerides; LDL; low density lipoproteins; HDL; high density lipoproteins; PASI; psoriasis area and severity index; PPARs; peroxisome proliferator activated receptors; IL; interleukin;
A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus
Keywords: CD26KO; CD26/DPPIV knockout; DPPIV; dipeptidyl peptidase IV; DPPIV-Tg; CD26/DPPIV transgenic; i.d.; intradermal; IMQ; imiquimod; i.p.; intraperitoneal; NK-1R; nuerokinin-1 receptor; PSO; psoriasis; rsCD26(DPPIV+); recombinant soluble CD26 protein containi
Quercitrin extracted from Tartary buckwheat alleviates imiquimod-induced psoriasis-like dermatitis in mice by inhibiting the Th17 cell response
Keywords: Quercitrin; Psoriasis; Keratinocyte; Th17 cell; Cyclosporine A; YDHH; quercitrin; IMQ; imiquimod; LPS; lipopolysaccharide; CsA; cyclosporine A; IL; interleukin; TNF; tumor necrosis factor; IFN; interferon gamma; Th1; T-helper 1 cell; Th17; T-helper 17 cel
Complement C3 Exacerbates Imiquimod-Induced Skin Inflammation and Psoriasiform Dermatitis
Keywords: IMQ; imiquimod; WT; wild type;
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses
Keywords: Newborn; dendritic cells; Toll-like receptor 8; polymersome; nanoparticle; BCG; vaccine; Ag85B; Antigen 85B; APC; Antigen-presenting cell; BMDC; Bone marrow-derived dendritic cell; DC; Dendritic cell; FITC; Fluorescein isothiocyanate; HBV; Hepatitis B v
Topically Delivered Tumor Necrosis Factor-α-Targeted Gene Regulation for Psoriasis
Keywords: 3D; three dimensional; IMQ; imiquimod; L-SNA; liposomal-cored spherical nucleic acid; NHEK; normal human epidermal keratinocyte; Scr; scrambled liposomal-cored spherical nucleic acid control sample; SNA; spherical nucleic acid; TNF-α; tumor necrosis fact
Psoriatic inflammation enhances allergic airway inflammation through IL-23/STAT3 signaling in a murine model
Keywords: Psoriasis; Asthma; IL-23; STAT3; Th17; BAL; bronchoalveolar lavage; CE; cockroach extract; i.n.; intranasal; STAT3; signal transducer and activator of transcription 3; RORC; retinoic acid receptor-related orphan receptor C; IMQ; imiquimod;
Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis
Keywords: AD; atopic dermatitis; CCL; CC chemokine ligand; IMQ; imiquimod; KO; knockout; Th; T helper; TLR; toll-like receptor; TNF; tumor necrosis factor; TRIM32; tripartite motif-containing 32; WT; wild type;
Spread of Psoriasiform Inflammation to Remote Tissues Is Restricted by the Atypical Chemokine Receptor ACKR2
Keywords: ACKR2; atypical chemokine receptor 2; IMQ; imiquimod; PASI; Psoriasis Area Severity Index; WT; wild type;
Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans
Keywords: AD; atopic dermatitis; AhR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor nuclear translocator; FICZ; 6-formylindolo(3,2-b)carbazole; IMQ; imiquimod; KO; knockout; Nrf2; nuclear factor-erythroid 2-related factor-2; Th17; T helper type 17;
Increased βTrCP are associated with imiquimod-induced psoriasis-like skin inflammation in mice via NF-κB signaling pathway
Keywords: βTrCP; β-transducin repeat-containing protein; TNF; tumor necrosis factor; IMQ; animal model of imiquimod; IPI; induced psoriasis-like inflammation; ICAM-1; intercellular adhesion molecule 1; IL; interleukin; NF; nuclear factor; Th1; type 1 T; Psoriasis
Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Keywords: Bmp; bone morphogenetic protein; Bu; bulge; DETC; dendritic epidermal T cells; gd T cells; gamma delta T cells; HF; hair follicle; 2°HG; secondary hair germ; HFSC; hair follicle stem cell; IF; infundibulum; IFE; interfollicular epidermis; IMQ; imiquimod;
The Exonuclease Trex2 Shapes Psoriatic Phenotype
Keywords: IMQ; imiquimod; wt; wild type;
Increased Lipocalin-2 Contributes to the Pathogenesis of Psoriasis by Modulating Neutrophil Chemotaxis and Cytokine Secretion
Keywords: dHL-60; differentiated human leukaemia-60; Erk; extracellular signal-regulated kinase; IMQ; imiquimod; Lcn2; lipocalin-2; MAPK; mitogen-activated protein kinase; rmLcn2; recombinant Lcn2; TNF; tumor necrosis factor;
Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation
Keywords: TGP; total glucosides of paeony; PF; paeoniflorin; RA; rheumatoid arthritis; SS; Sjögren's syndrome; SLE; systemic lupus erythematosus; CIA; collagen-induced arthritis; NOD; non-obese diabetic; IMQ; imiquimod; iNOS; inducible nitric oxide synthase; MIP-2
Imiquimod-induced psoriasis-like skin inflammation is suppressed by BET bromodomain inhibitor in mice through RORC/IL-17A pathway modulation
Keywords: IMQ; imiquimod; MPO; myeloperoxidase; RORC; retinoic acid receptor-related orphan receptor C; BET; bromodomain and extraterminal domain; BET bromodomains; Imiquimod; Retinoic acid receptor-related orphan receptor C; IL-17A; Psoriasis;
Topical delivery of anti-TNFα siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo
Keywords: Cap; Capsaicin; C-CyLiPn; Cap encapsulated CyLiPn; CGRP; Calcitonin gene related peptide; CLSM; Confocal laser scanning microscopy; CS-CyLiPn; Cap + siTNFα incorporated CyLiPn; CyLiPn; Lipid-polymer nanocarriers; FACS; Fluorescence-activated cells sort
Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways
Keywords: Toll-like receptor 8; innate immunity; neonate; newborn; alum; adjuvant; adenosine; IL-1β; caspase-1; inflammasome; APC; Antigen-presenting cell; cAMP; Cyclic adenosine monophosphate; CBMC; Cord blood mononuclear cell; db-cAMP; Dibutyryl-cAMP; DC; Dendri