Keywords: سم شناسی in vitro; AOP(s); adverse outcome pathway(s); IATAs; integrated approaches to testing and assessment; KE(s); key event(s); MIE(s); molecular initiating event(s); OECD; Organization for Economic Cooperation and Development; adverse outcome pathway; in vitro toxicolo
مقالات ISI سم شناسی in vitro (ترجمه نشده)
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Keywords: سم شناسی in vitro; Immunotoxicology; Environmental exposures; Contaminant mixtures; Influenza A virus; Susceptibility to disease; In vitro toxicology;
Keywords: سم شناسی in vitro; Clove cigarette; Kretek; Flavor; Ingredient; In vitro toxicology; Smoke chemistry;
Keywords: سم شناسی in vitro; MUTZ-LC; MUTZ-3 derived Langerhans Cells; CMC; cytokine maturation cocktail; MUTZ-3; Migration; Sensitizer; Dendritic cell; In vitro toxicology; Alternative method; Chemokine;
Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment
Keywords: سم شناسی in vitro; In vitro toxicology; Xenobiotic safety; Hepatotoxicity; 3D cell culture models; Liver spheroids;
In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Keywords: سم شناسی in vitro; Drug delivery systems; Liposomes; Micelles; In vitro toxicology; Nanomedicine; Hepatocytes; Lung epithelial cells; Comet assay;
The long and winding road of progress in the use of in vitro data for risk assessment purposes: From “carnation test” to integrated testing strategies
Keywords: سم شناسی in vitro; In vitro toxicology; Biomarkers; Quantitative in vitro-in vivo extrapolation;
PM10 in a background urban site: Chemical characteristics and biological effects
Keywords: سم شناسی in vitro; PM10; Air quality; In vitro toxicology; Genotoxicity; PCA;
The application of 3D cell models to support drug safety assessment: Opportunities & challenges
Keywords: سم شناسی in vitro; Drug safety assessment; Predictive toxicology; In vitro toxicology; Mechanistic toxicology; 3R
NCTC 2544 and IL-18 production: A tool for the identification of contact allergens
Keywords: سم شناسی in vitro; Allergic contact dermatitis; Keratinocytes; Cytokines; Immunotoxicology; In vitro toxicology; Alternative method;
Establishment of an in vitro photoassay using THP-1 cells and IL-8 to discriminate photoirritants from photoallergens
Keywords: سم شناسی in vitro; Photosensitization; In vitro toxicology; Dendritic cells; IL-8;
In vitro nanotoxicity of single-walled carbon nanotube–dendrimer nanocomplexes against murine myoblast cells
Keywords: سم شناسی in vitro; Nanotoxicity; Nanomedicine; In vitro toxicology; C2C12 cell line; SWCNT; PAMAM dendrimer
Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide
Keywords: سم شناسی in vitro; Graphene oxide; Graphene; In vitro toxicology;
Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: Results with model toxicants aflatoxin B1, cyclo
Keywords: سم شناسی in vitro; Animal alternatives; In vitro toxicology; Metabolic activation; Detoxification; Human hepatocytes
Porcine Corneal Ocular Reversibility Assay (PorCORA) predicts ocular damage and recovery for global regulatory agency hazard categories
Keywords: سم شناسی in vitro; In vitro toxicology; Alternative toxicology methods; Ex vivo corneal assay; Long-term mammalian corneal culture; Ocular irritation reversibility; Corneal re-epithelization/healing;
Silver nanoparticles exert a long-lasting antiproliferative effect on human keratinocyte HaCaT cell line
Keywords: سم شناسی in vitro; Silver; Nanoparticles; HaCaT cell line; In vitro toxicology; Dermal toxicity
In vitro detection of contact allergens: Development of an optimized protocol using human peripheral blood monocyte-derived dendritic cells
Keywords: سم شناسی in vitro; In vitro toxicology; Sensitization; Dendritic cell; CD86; Alternative method
Evaluation of a modified comet assay to detect DNA damage in mammalian sperm exposed in vitro to different mutagenic compounds
Keywords: سم شناسی in vitro; Comet assay; ReProComet; Reproductive toxicology; Bull sperm; DNA damage; In vitro toxicology
Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro
Keywords: سم شناسی in vitro; Hpersensitivity; Dndritic cells; Cytokines; In vitro toxicology; Alternative method; Allergen potency
Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity
Keywords: سم شناسی in vitro; Gene Ontology; In vitro toxicology; Microarray; Mouse embryo; Neural tube defects; Teratogen; Toxicogenomics; Valproic acid
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens
Keywords: سم شناسی in vitro; Respiratory allergy; Contact dermatitis; Keratinocytes; Cytokines; In vitro toxicology; Alternative method
Current in vitro methods in nanoparticle risk assessment: Limitations and challenges
Keywords: سم شناسی in vitro; Nanoparticles; Nanoparticle properties; In vitro toxicology; Particle assay interference; New toxicology detection systems
A comparison between the responses of neutral red and acridine orange: Acridine orange should be preferential and alternative to neutral red as a dye for the monitoring of contaminants by means of biological sensors
Keywords: سم شناسی in vitro; Acridine orange; Neutral red; In vitro toxicology
The plasticizer dibutyl phthalate (DBP) potentiates chemical allergen-induced THP-1 activation
Keywords: سم شناسی in vitro; Dibutyl phthalate; Adjuvant effect; Contact dermatitis; Keratinocytes; Dendritic cells; In vitro toxicology;
Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment)
Keywords: سم شناسی in vitro; In vitro toxicology; Alternative methods; Eye irritation; Phototoxicity; Embryotoxicity; Skin irritation; Corrosion; Embryonic stem cell test (EST)
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naïve THP-1 cells
Keywords: سم شناسی in vitro; Respiratory allergy; Contact dermatitis; Dendritic cells; Cytokines; In vitro toxicology; Alternative method
Understanding mechanisms of toxicity: Insights from drug discovery research
Keywords: سم شناسی in vitro; High-throughput screening; High-content screening; In vitro toxicology; Mechanism of toxicity; Systems toxicology; Predictive toxicology
Precision-cut tissue chips as an in vitro toxicology system
Keywords: سم شناسی in vitro; In vitro toxicology; Fluorescent probes; Precision-cut tissue slices; Precision-cut liver slices
Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72 h
Keywords: سم شناسی in vitro; Tissue slices; Lung slices; Cytochromes P450; Conjugation enzymes; In vitro toxicology
Epithelial barrier characteristics and expression of cell adhesion molecules in proximal tubule-derived cell lines commonly used for in vitro toxicity studies
Keywords: سم شناسی in vitro; Proximal tubule; In vitro toxicology; Renal epithelial cell lines; Cell adhesion molecules; E-cadherin; N-cadherin; Claudin-2; Claudin-7; Occludin; ZO-1; LLC-PK1 cells; OK cells; NRK-52E cells; HK-2 cells; Human proximal tubule epithelial cells
In vitro studies: What is their role in toxicology?
Keywords: سم شناسی in vitro; Inhaled environmental pollutants; Particles; In vitro toxicology; Advantages; Limitations; Mechanisms;